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Faculty Physicians

Lawrence M. Lewis, MD

Professor, Emergency Medicine and Medicine

Specialty Areas

Emergency Medicine

Board Certifications

Emergency Medicine
Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Emergency medicine, injury prevention

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Barnes-Jewish Hospital

1 Barnes-Jewish Hospital Plaza
St. Louis, MO 63110

Office Phone: 314-758-6787
Fax: 314-362-0478

Education

Education

Residency: Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 1979
Medical Degree: University of Miami Medical School, Miami, Florida 1976
AA: University of Florida, Gainesville, Florida 1972

Publication & Research

Publication & Research

The Million Hearts initiative: Guidelines and best practices.
Melnyk BM, Orsolini L, Gawlik K, Braun LT, Chyun DA, Conn VS, Dunbar-Jacob J, Lewis LM, Melkus GD, Millan A, Rice VH, Wilbur J, Nowlin S, Olin AR
Nurse Pract. 2016 Feb 18; 41(2)46-53. doi: 10.1097/01.NPR.0000476372.04620.7a.

PMID:
    26745737
    [PubMed - in process]
Related citations


Ability of Serum Glial Fibrillary Acidic Protein, Ubiquitin C-Terminal Hydrolase-L1, and S100B To Differentiate Normal and Abnormal Head Computed Tomography Findings in Patients with Suspected Mild or Moderate Traumatic Brain Injury.
Welch RD, Ayaz SI, Lewis LM, Unden J, Chen JY, Mika VH, Saville B, Tyndall JA, Nash M, Buki A, Barzo P, Hack D, Tortella FC, Schmid K, Hayes RL, Vossough A, Sweriduk ST, Bazarian JJ
J Neurotrauma. 2016 Jan 15; 33(2)203-14. doi: 10.1089/neu.2015.4149.

PMID:
    26467555
    [PubMed - in process]
Related citations


Could robots become authentic companions in nursing care?
Metzler TA, Lewis LM, Pope LC
Nurs Philos. 2016 Jan; 17(1)36-48. doi: 10.1111/nup.12101.

PMID:
    26333299
    [PubMed - in process]
Related citations


Efficacy of a new intravenous β2-adrenergic agonist (bedoradrine, MN-221) for patients with an acute exacerbation of asthma.
House SL, Matsuda K, O'Brien G, Makhay M, Iwaki Y, Ferguson I, Lovato LM, Lewis LM
Respir Med. 2015 Oct; 109(10)1268-73. doi: 10.1016/j.rmed.2015.08.003.

PMID:
    26324315
    [PubMed - in process]
Related citations


The Promise and Ambiguity of eHealth Research.
Lewis LM
Nurs Res. 2015 May-Jun; 64(3)157-8. doi: 10.1097/NNR.0000000000000097.

PMID:
    25932695
    [PubMed - indexed for MEDLINE]
Related citations


Application of process analytical technology for monitoring freeze-drying of an amorphous protein formulation: use of complementary tools for real-time product temperature measurements and endpoint detection.
Schneid SC, Johnson RE, Lewis LM, Stärtzel P, Gieseler H
J Pharm Sci. 2015 May; 104(5)1741-9. doi: 10.1002/jps.24389.

PMID:
    25691354
    [PubMed - indexed for MEDLINE]
Related citations


Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7.
Jalan-Sakrikar N, Field JR, Klar R, Mattmann ME, Gregory KJ, Zamorano R, Engers DW, Bollinger SR, Weaver CD, Days EL, Lewis LM, Utley TJ, Hurtado M, Rigault D, Acher F, Walker AG, Melancon BJ, Wood MR, Lindsley CW, Conn PJ, Xiang Z, Hopkins CR, Niswender CM
ACS Chem Neurosci. 2014 Dec 17; 5(12)1221-37. doi: 10.1021/cn500153z.

PMID:
    25225882
    [PubMed - indexed for MEDLINE]
Related citations


Ecallantide for the acute treatment of angiotensin-converting enzyme inhibitor-induced angioedema: a multicenter, randomized, controlled trial.
Lewis LM, Graffeo C, Crosley P, Klausner HA, Clark CL, Frank A, Miner J, Iarrobino R, Chyung Y
Ann Emerg Med. 2015 Feb; 65(2)204-13. doi: 10.1016/j.annemergmed.2014.07.014.

PMID:
    25182544
    [PubMed - indexed for MEDLINE]
Related citations


Repeated dyspnea score and percent FEV1 are modest predictors of hospitalization/relapse in patients with acute asthma exacerbation.
Schneider JE, Lewis LM, Ferguson I, House SL, Liu J, Matsuda K, Johnson K
Respir Med. 2014 Sep; 108(9)1284-91. doi: 10.1016/j.rmed.2014.06.006.

PMID:
    25087835
    [PubMed - indexed for MEDLINE]
Related citations


Response.
Lewis LM, Ferguson I, House SL, Aubuchon K, Schneider J, Johnson K, Matsuda K
Chest. 2014 Jun; 145(6)1436. doi: 10.1378/chest.14-0344.

PMID:
    24889452
    [PubMed - indexed for MEDLINE]
Related citations


Angioedema: etiology, pathophysiology, current and emerging therapies.
Lewis LM
J Emerg Med. 2013 Nov; 45(5)789-96. doi: 10.1016/j.jemermed.2013.03.045.

PMID:
    23992848
    [PubMed - indexed for MEDLINE]
Related citations


Scaffold Hopping Affords a Highly Selective <i>in vitro</i> and <i>in vivo</i> T-Type Calcium Inhibitor Probe Free From IP Issues
Xie X, Brogan JT, Schulte ML, Mi D, Yu H, Dawson ES, Li M, McManus O, Engers J, Lewis LM, Thompson A, Jones CK, Weaver CD, Lindsley CW
. 2010;

PMID:
    23762962
    [PubMed]
Related citations


Development of the First Highly Selective mAChR 5 (M<sub>5</sub>) Positive Allosteric Modulator (PAM)
Bridges TM, Lewis LM, Weaver CD, Wood MR, Daniels JS, Conn PJ, Lindsley CW
. 2010;

PMID:
    23762960
    [PubMed]
Related citations


Discovery of a Highly Selective <i>in vitro</i> and <i>in vivo</i> M<sub>4</sub> Positive Allosteric Modulator (PAM) Series with Greatly Improved Human Receptor Activity
Bridges TM, Niswender CM, Jones CK, Lewis LM, Weaver CD, Wood MR, Daniels JS, Conn PJ, Lindsley CW
. 2010;

PMID:
    23762955
    [PubMed]
Related citations


Enhancing adherence of antihypertensive regimens in hypertensive African-Americans: current and future prospects.
Lewis LM, Ogedegbe C, Ogedegbe G
Expert Rev Cardiovasc Ther. 2012 Nov; 10(11)1375-80. doi: 10.1586/erc.12.138.

PMID:
    23244358
    [PubMed - indexed for MEDLINE]
Related citations


Identification and characterization of a compound that protects cardiac tissue from human Ether-à-go-go-related gene (hERG)-related drug-induced arrhythmias.
Potet F, Lorinc AN, Chaigne S, Hopkins CR, Venkataraman R, Stepanovic SZ, Lewis LM, Days E, Sidorov VY, Engers DW, Zou B, Afshartous D, George AL Jr, Campbell CM, Balser JR, Li M, Baudenbacher FJ, Lindsley CW, Weaver CD, Kupershmidt S
J Biol Chem. 2012 Nov 16; 287(47)39613-25. doi: 10.1074/jbc.M112.380162.

PMID:
    23033485
    [PubMed - indexed for MEDLINE]
Related citations


Racial disparity in emergency department triage.
Schrader CD, Lewis LM
J Emerg Med. 2013 Feb; 44(2)511-8. doi: 10.1016/j.jemermed.2012.05.010.

PMID:
    22818646
    [PubMed - indexed for MEDLINE]
Related citations


Patterns and factors associated with intensive use of ED services: implications for allocating resources.
Ruger JP, Lewis LM, Richter CJ
Am J Emerg Med. 2012 Nov; 30(9)1884-94. doi: 10.1016/j.ajem.2012.04.001.

PMID:
    22795412
    [PubMed - indexed for MEDLINE]
Related citations


Serum levels of ubiquitin C-terminal hydrolase distinguish mild traumatic brain injury from trauma controls and are elevated in mild and moderate traumatic brain injury patients with intracranial lesions and neurosurgical intervention.
Papa L, Lewis LM, Silvestri S, Falk JL, Giordano P, Brophy GM, Demery JA, Liu MC, Mo J, Akinyi L, Mondello S, Schmid K, Robertson CS, Tortella FC, Hayes RL, Wang KK
J Trauma Acute Care Surg. 2012 May; 72(5)1335-44. doi: 10.1097/TA.0b013e3182491e3d.

PMID:
    22673263
    [PubMed - indexed for MEDLINE]
Related citations


Emergency department patients with diabetes have better glycemic control when they have identifiable primary care providers.
Horwitz DA, Schwarz ES, Scott MG, Lewis LM
Acad Emerg Med. 2012 Jun; 19(6)650-5. doi: 10.1111/j.1553-2712.2012.01366.x.

PMID:
    22632540
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Evaluating the utility of specific biomarkers to identify the presence of traumatic brain injury. (Sponsor: Department of Defense.  Biomarkers of Brain Injury: Magnitude, complications, and Outcome of Mild, and Moderate TBI.)

Novel therapies in the treatment of acute exacerbations of asthma (Sponsors: Medicinova; Electrocore)

Emergency Management of Anaphylaxis and Angioedema (Sponsors: Dey; Dyax)

Health Policy and Healthcare Services (Sponsors: none)