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Kristin Guilliams, MD

Assistant Professor, Neurology
Division of Pediatric Neurology
Assistant Professor, Pediatrics
Division of Critical Care Medicine

Specialty Areas

Pediatric Neurology
Pediatric Critical Care Medicine

Board Certifications

Pediatrics
Pediatric Critical Care
Psychiatry and Neurology

Hospital Affiliations

St. Louis Children's Hospital
Barnes-Jewish Hospital

Areas of Clinical Interest

Pediatric stroke, vasculopathy/moyamoya disease, neurologic complications of sickle cell disease, pediatric neurocritical care, delirium, posterior reversible encephalopathy syndrome (PRES)

  • Location(s)
  • Education
  • Publication & Research
  • Videos

Location(s)

Location(s)

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: C/D
Floor: 2

Education

Education

Fellowship: Pediatric Critical Care, Washington University School of Medicine, St. Louis, Missouri 2014
Residency: Pediatric Neurology, Washington University School of Medicine, St. Louis, Missouri 2011
Residency: Pediatrics, Washington University School of Medicine, St. Louis, Missouri 2008
Medical Degree: University of Virginia School of Medicine, Charlottesville, Virginia 2006
Bachelor of Science: Furman University, Greenville, South Carolina 2002

Publication & Research

Publication & Research

Arterial Ischemic Stroke Secondary to Cardiac Disease in Neonates and Children.
Chung MG, Guilliams KP, Wilson JL, Beslow LA, Dowling MM, Friedman NR, Hassanein SMA, Ichord R, Jordan LC, Mackay MT, Rafay MF, Rivkin M, Torres M, Zafeiriou D, deVeber G, Fox CK, International Pediatric Stroke Study Investigators.
Pediatr Neurol. 2019 Jun 27; pii: S0887-8994(19)30447-3. doi: 10.1016/j.pediatrneurol.2019.06.008.

PMID:
    31371125
    [PubMed - as supplied by publisher]
Related citations


Characteristics and Outcome in Children With Craniectomy Following Acute Ischemic Stroke in the International Pediatric Stroke Study.
Lehman LL, DeVeber G, Pergami P, Guilliams KP, Chung M, Felling R, Dowling MM, Rivkin MJ
J Child Neurol. 2019 Jul 8; 883073819855534. doi: 10.1177/0883073819855534.

PMID:
    31282248
    [PubMed - as supplied by publisher]
Related citations


Higher executive abilities following a blood transfusion in children and young adults with sickle cell disease.
Hood AM, King AA, Fields ME, Ford AL, Guilliams KP, Hulbert ML, Lee JM, White DA
Pediatr Blood Cancer. 2019 Oct; 66(10)e27899. doi: 10.1002/pbc.27899.

PMID:
    31267645
    [PubMed - in process]
Related citations


Arteriopathy Influences Pediatric Ischemic Stroke Presentation, but Sickle Cell Disease Influences Stroke Management.
Guilliams KP, Kirkham FJ, Holzhauer S, Pavlakis S, Philbrook B, Amlie-Lefond C, Noetzel MJ, Dlamini N, Sharma M, Carpenter JL, Fox CK, Torres M, Ichord RN, Jordan LC, Dowling MM
Stroke. 2019 May; 50(5)1089-1094. doi: 10.1161/STROKEAHA.118.022800.

PMID:
    31009343
    [PubMed - in process]
Related citations


Hydroxyurea reduces cerebral metabolic stress in patients with sickle cell anemia.
Fields ME, Guilliams KP, Ragan D, Binkley MM, Mirro A, Fellah S, Hulbert ML, Blinder M, Eldeniz C, Vo K, Shimony JS, Chen Y, McKinstry RC, An H, Lee JM, Ford AL
Blood. 2019 May 30; 133(22)2436-2444. doi: 10.1182/blood-2018-09-876318.

PMID:
    30858231
    [PubMed - in process]
Related citations


Advances in Understanding Ischemic Stroke Physiology and the Impact of Vasculopathy in Children With Sickle Cell Disease.
Guilliams KP, Fields ME, Dowling MM
Stroke. 2019 Feb; 50(2)266-273. doi: 10.1161/STROKEAHA.118.020482.

PMID:
    30661504
    [PubMed - in process]
Related citations


Optimizing Neurocritical Care Follow-Up Through the Integration of Neuropsychology.
Dodd JN, Hall TA, Guilliams K, Guerriero RM, Wagner A, Malone S, Williams CN, Hartman ME, Piantino J
Pediatr Neurol. 2018 Dec; 8958-62. doi: 10.1016/j.pediatrneurol.2018.09.007.

PMID:
    30442440
    [PubMed - in process]
Related citations


Silent infarcts in sickle cell disease occur in the border zone region and are associated with low cerebral blood flow.
Ford AL, Ragan DK, Fellah S, Binkley MM, Fields ME, Guilliams KP, An H, Jordan LC, McKinstry RC, Lee JM, DeBaun MR
Blood. 2018 Oct 18; 132(16)1714-1723. doi: 10.1182/blood-2018-04-841247.

PMID:
    30061156
    [PubMed - indexed for MEDLINE]
Related citations


Regional oxygen extraction predicts border zone vulnerability to stroke in sickle cell disease.
Fields ME, Guilliams KP, Ragan DK, Binkley MM, Eldeniz C, Chen Y, Hulbert ML, McKinstry RC, Shimony JS, Vo KD, Doctor A, An H, Ford AL, Lee JM
Neurology. 2018 Mar 27; 90(13)e1134-e1142. doi: 10.1212/WNL.0000000000005194.

PMID:
    29500287
    [PubMed - indexed for MEDLINE]
Related citations


Red cell exchange transfusions lower cerebral blood flow and oxygen extraction fraction in pediatric sickle cell anemia.
Guilliams KP, Fields ME, Ragan DK, Eldeniz C, Binkley MM, Chen Y, Comiskey LS, Doctor A, Hulbert ML, Shimony JS, Vo KD, McKinstry RC, An H, Lee JM, Ford AL
Blood. 2018 Mar 1; 131(9)1012-1021. doi: 10.1182/blood-2017-06-789842.

PMID:
    29255068
    [PubMed - indexed for MEDLINE]
Related citations


Harnessing Neuroimaging Capability in Pediatric Stroke: Proceedings of the Stroke Imaging Laboratory for Children Workshop.
Dlamini N, Wintermark M, Fullerton H, Strother S, Lee W, Bjornson B, Guilliams KP, Miller S, Kirton A, Filippi CG, Linds A, Askalan R, deVeber G
Pediatr Neurol. 2017 Apr; 693-10. doi: 10.1016/j.pediatrneurol.2017.01.006.

PMID:
    28259513
    [PubMed - indexed for MEDLINE]
Related citations


Large-Vessel Vasculopathy in Children With Sickle Cell Disease: A Magnetic Resonance Imaging Study of Infarct Topography and Focal Atrophy.
Guilliams KP, Fields ME, Ragan DK, Chen Y, Eldeniz C, Hulbert ML, Binkley MM, Rhodes JN, Shimony JS, McKinstry RC, Vo KD, An H, Lee JM, Ford AL
Pediatr Neurol. 2017 Apr; 6949-57. doi: 10.1016/j.pediatrneurol.2016.11.005.

PMID:
    28159432
    [PubMed - indexed for MEDLINE]
Related citations


Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children.
Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Browning B, Pemberton VL, Page K, Gildea MR, Scholefield BR, Shankaran S, Hutchison JS, Berger JT, Ofori-Amanfo G, Newth CJ, Topjian A, Bennett KS, Koch JD, Pham N, Chanani NK, Pineda JA, Harrison R, Dalton HJ, Alten J, Schleien CL, Goodman DM, Zimmerman JJ, Bhalala US, Schwarz AJ, Porter MB, Shah S, Fink EL, McQuillen P, Wu T, Skellett S, Thomas NJ, Nowak JE, Baines PB, Pappachan J, Mathur M, Lloyd E, van der Jagt EW, Dobyns EL, Meyer MT, Sanders RC Jr, Clark AE, Dean JM, THAPCA Trial Investigators.
N Engl J Med. 2017 Jan 26; 376(4)318-329. doi: 10.1056/NEJMoa1610493.

PMID:
    28118559
    [PubMed - indexed for MEDLINE]
Related citations


Prolonged or recurrent acute seizures after pediatric arterial ischemic stroke are associated with increasing epilepsy risk.
Fox CK, Mackay MT, Dowling MM, Pergami P, Titomanlio L, Deveber G, SIPS Investigators.
Dev Med Child Neurol. 2017 Jan; 59(1)38-44. doi: 10.1111/dmcn.13198.

PMID:
    27422813
    [PubMed - indexed for MEDLINE]
Related citations


Reduction in Overt and Silent Stroke Recurrence Rate Following Cerebral Revascularization Surgery in Children with Sickle Cell Disease and Severe Cerebral Vasculopathy.
Hall EM, Leonard J, Smith JL, Guilliams KP, Binkley M, Fallon RJ, Hulbert ML
Pediatr Blood Cancer. 2016 Aug; 63(8)1431-7. doi: 10.1002/pbc.26022.

PMID:
    27106860
    [PubMed - indexed for MEDLINE]
Related citations


Emergency Neurological Life Support: Acute Ischemic Stroke.
Gross H, Guilliams KP, Sung G
Neurocrit Care. 2015 Dec; 23 Suppl 2S94-102. doi: 10.1007/s12028-015-0159-0.

PMID:
    26438453
    [PubMed - indexed for MEDLINE]
Related citations


Higher-than-expected prevalence of silent cerebral infarcts in children with hemoglobin SC disease.
Guilliams KP, Fields ME, Hulbert ML
Blood. 2015 Jan 8; 125(2)416-7. doi: 10.1182/blood-2014-10-605964.

PMID:
    25573975
    [PubMed - indexed for MEDLINE]
Related citations


Stroke in children with cardiac disease: report from the International Pediatric Stroke Study Group Symposium.
Sinclair AJ, Fox CK, Ichord RN, Almond CS, Bernard TJ, Beslow LA, Chan AK, Cheung M, deVeber G, Dowling MM, Friedman N, Giglia TM, Guilliams KP, Humpl T, Licht DJ, Mackay MT, Jordan LC
Pediatr Neurol. 2015 Jan; 52(1)5-15. doi: 10.1016/j.pediatrneurol.2014.09.016.

PMID:
    25532775
    [PubMed - indexed for MEDLINE]
Related citations


Pathophysiology and Management of Moderate and Severe Traumatic Brain Injury in Children.
Guilliams K, Wainwright MS
J Child Neurol. 2016 Jan; 31(1)35-45. doi: 10.1177/0883073814562626.

PMID:
    25512361
    [PubMed - indexed for MEDLINE]
Related citations


Hypothermia for pediatric refractory status epilepticus.
Guilliams K, Rosen M, Buttram S, Zempel J, Pineda J, Miller B, Shoykhet M
Epilepsia. 2013 Sep; 54(9)1586-94. doi: 10.1111/epi.12331.

PMID:
    23906244
    [PubMed - indexed for MEDLINE]
Related citations

Videos

Videos

Areas of Research Interest

Pediatric stroke, cerebral blood flow and metabolism, sickle cell disease