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Ketan J Patel, MD

Clinical Instructor, Emergency Medicine

Specialty Areas

Emergency Medicine

Board Certifications

Internal Medicine

Hospital Affiliations

Barnes-Jewish West County Hospital

Areas of Clinical Interest

Emergency medicine, hypertension, trauma, diabetes

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Barnes-Jewish West County Hospital

12634 Olive Blvd.
Creve Coeur, MO 63141

Office Phone: 314-996-8472
Fax: 314-996-8471

Education

Education

MBBS: University of Bombay, Bombay India 1988
Residency: 1993
Chief Resident: 1993
Research Fellowship: Wayne State University, Detroit, Michigan 1990

Publication & Research

Publication & Research

Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells.
Garaycoechea JI, Crossan GP, Langevin F, Mulderrig L, Louzada S, Yang F, Guilbaud G, Park N, Roerink S, Nik-Zainal S, Stratton MR, Patel KJ
Nature. 2018 Jan 11; 553(7687)171-177. doi: 10.1038/nature25154.

PMID:
    29323295
    [PubMed - in process]
Related citations


Dietary vitamin D3 deficiency exacerbates sinonasal inflammation and alters local 25(OH)D3 metabolism.
Mulligan JK, Pasquini WN, Carroll WW, Williamson T, Reaves N, Patel KJ, Mappus E, Schlosser RJ, Atkinson C
PLoS One. 2017; 12(10)e0186374. doi: 10.1371/journal.pone.0186374.

PMID:
    29045457
    [PubMed - indexed for MEDLINE]
Related citations


Risk Factors for Repeat Debridement, Spacer Retention, Amputation, Arthrodesis, and Mortality After Removal of an Infected Total Knee Arthroplasty With Spacer Placement.
Cancienne JM, Granadillo VA, Patel KJ, Werner BC, Browne JA
J Arthroplasty. 2017 Sep 5; pii: S0883-5403(17)30760-X. doi: 10.1016/j.arth.2017.08.037.

PMID:
    28958659
    [PubMed - as supplied by publisher]
Related citations


Narcotic Use and Total Knee Arthroplasty.
Cancienne JM, Patel KJ, Browne JA, Werner BC
J Arthroplasty. 2018 Jan; 33(1)113-118. doi: 10.1016/j.arth.2017.08.006.

PMID:
    28887020
    [PubMed - in process]
Related citations


Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism.
Burgos-Barragan G, Wit N, Meiser J, Dingler FA, Pietzke M, Mulderrig L, Pontel LB, Rosado IV, Brewer TF, Cordell RL, Monks PS, Chang CJ, Vazquez A, Patel KJ
Nature. 2017 Aug 31; 548(7669)549-554. doi: 10.1038/nature23481.

PMID:
    28813411
    [PubMed - in process]
Related citations


Of sizzling steaks and DNA repair.
Dingler FA, Patel KJ
Science. 2017 Jul 14; 357(6347)130-131. doi: 10.1126/science.aan8293.

PMID:
    28706026
    [PubMed - indexed for MEDLINE]
Related citations


A 2-aza-Cope reactivity-based platform for ratiometric fluorescence imaging of formaldehyde in living cells.
Brewer TF, Burgos-Barragan G, Wit N, Patel KJ, Chang CJ
Chem Sci. 2017 May 1; 8(5)4073-4081. doi: 10.1039/c7sc00748e.

PMID:
    28580121
    [PubMed]
Related citations


Development of a General Aza-Cope Reaction Trigger Applied to Fluorescence Imaging of Formaldehyde in Living Cells.
Bruemmer KJ, Walvoord RR, Brewer TF, Burgos-Barragan G, Wit N, Pontel LB, Patel KJ, Chang CJ
J Am Chem Soc. 2017 Apr 19; 139(15)5338-5350. doi: 10.1021/jacs.6b12460.

PMID:
    28375637
    [PubMed - in process]
Related citations


Evaluation of cardioprotective effect of aqueous extract of <i>Allium cepa</i> Linn. bulb on isoprenaline-induced myocardial injury in Wistar albino rats.
Kharadi GB, Patel KJ, Purohit BM, Baxi SN, Tripathi CB
Res Pharm Sci. 2016 Oct; 11(5)419-427.

PMID:
    27920825
    [PubMed]
Related citations


Xpf suppresses the mutagenic consequences of phagocytosis in Dictyostelium.
Pontel LB, Langenick J, Rosado IV, Zhang XY, Traynor D, Kay RR, Patel KJ
J Cell Sci. 2016 Dec 15; 129(24)4449-4454.

PMID:
    27872153
    [PubMed - indexed for MEDLINE]
Related citations


Can higher end tonometers be used interchangeably in routine clinical practice?
Patel KJ, Jain SP, Kapadia PR, Patel NV, Patel S, Patel V
Indian J Ophthalmol. 2016 Feb; 64(2)132-5. doi: 10.4103/0301-4738.179723.

PMID:
    27050348
    [PubMed - indexed for MEDLINE]
Related citations


Evaluation of cardioprotective effect of aqueous extract of Garcinia indica Linn. fruit rinds on isoprenaline-induced myocardial injury in Wistar albino rats.
Patel KJ, Panchasara AK, Barvaliya MJ, Purohit BM, Baxi SN, Vadgama VK, Tripathi CB
Res Pharm Sci. 2015 Sep-Oct; 10(5)388-96.

PMID:
    26752987
    [PubMed]
Related citations


Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen.
Pontel LB, Rosado IV, Burgos-Barragan G, Garaycoechea JI, Yu R, Arends MJ, Chandrasekaran G, Broecker V, Wei W, Liu L, Swenberg JA, Crossan GP, Patel KJ
Mol Cell. 2015 Oct 1; 60(1)177-88. doi: 10.1016/j.molcel.2015.08.020.

PMID:
    26412304
    [PubMed - indexed for MEDLINE]
Related citations


Do mutational dynamics in stem cells explain the origin of common cancers?
Crossan GP, Garaycoechea JI, Patel KJ
Cell Stem Cell. 2015 Feb 5; 16(2)111-2. doi: 10.1016/j.stem.2015.01.009.

PMID:
    25658366
    [PubMed - indexed for MEDLINE]
Related citations


Ubiquitin-SUMO circuitry controls activated fanconi anemia ID complex dosage in response to DNA damage.
Gibbs-Seymour I, Oka Y, Rajendra E, Weinert BT, Passmore LA, Patel KJ, Olsen JV, Choudhary C, Bekker-Jensen S, Mailand N
Mol Cell. 2015 Jan 8; 57(1)150-64. doi: 10.1016/j.molcel.2014.12.001.

PMID:
    25557546
    [PubMed - indexed for MEDLINE]
Related citations


CRE: a cost effective and rapid approach for PCR-mediated concatenation of KRAS and EGFR exons: Rapid way to detect EGFR and KRAS mutations.
Ramteke MP, Patel KJ, Godbole M, Vyas M, Karve K, Choughule A, Prabhash K, Dutt A
F1000Res. 2015; 4160. doi: 10.12688/f1000research.6663.2.

PMID:
    27127615
    [PubMed]
Related citations


Abundance of the Fanconi anaemia core complex is regulated by the RuvBL1 and RuvBL2 AAA+ ATPases.
Rajendra E, Garaycoechea JI, Patel KJ, Passmore LA
Nucleic Acids Res. 2014 Dec 16; 42(22)13736-48. doi: 10.1093/nar/gku1230.

PMID:
    25428364
    [PubMed - indexed for MEDLINE]
Related citations


Transfecting pDNA to E. coli DH5α using bovine serum albumin nanoparticles as a delivery vehicle.
Wagh J, Patel KJ, Soni P, Desai K, Upadhyay P, Soni HP
Luminescence. 2015 Aug; 30(5)583-91. doi: 10.1002/bio.2789.

PMID:
    25345764
    [PubMed - indexed for MEDLINE]
Related citations


Laparoscopic repair of gastro-duodenal fistula secondary to band erosion.
Patel KJ, Byrne TK, Pullatt RC
J Minim Access Surg. 2014 Oct; 10(4)216-8. doi: 10.4103/0972-9941.141533.

PMID:
    25336826
    [PubMed]
Related citations


Maternal aldehyde elimination during pregnancy preserves the fetal genome.
Oberbeck N, Langevin F, King G, de Wind N, Crossan GP, Patel KJ
Mol Cell. 2014 Sep 18; 55(6)807-817. doi: 10.1016/j.molcel.2014.07.010.

PMID:
    25155611
    [PubMed - indexed for MEDLINE]
Related citations