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Faculty Physicians

Keith M. Rich, MD

Professor, Neurological Surgery, Neurobiology
and Radiology
Medical Director, St. Louis Gamma Knife Center

Specialty Areas

Neurological Surgery
Neuro Oncology
Gamma Knife
Neurovascular Disorders
Brain Tumors

Board Certifications

Neurological Surgery

Hospital Affiliations

Barnes-Jewish Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Neurovascular disorders, stereotactic radiosurgery, stereotactic surgery - Gamma Knife, cerebrovascular surgery including stroke, brain tumors, neuro-oncology, Vagus Nerve Stimulation implantation, trigeminal neuralgia, Pituitary Center

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Neuroscience Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: 314-362-3577
Fax: 314-362-2107

Education

Education

Fellowship: Neurological Surgery, Barnes-Jewish Hospital, St. Louis, Missouri 1984
Chief Residency: Neurological Surgery, Barnes-Jewish Hospital, St. Louis, Missouri 1982
Residency: Neurological Surgery, Barnes-Jewish Hospital, St. Louis, Missouri 1981
Medical Degree: Indiana University School of Medicine, Indianapolis, Indiana 1977
B.A.: Taylor University, Upland, Indiana 1974

Publication & Research

Publication & Research

Endovascular management of internal carotid artery injuries secondary to endonasal surgery: case series and review of the literature.
Sylvester PT, Moran CJ, Derdeyn CP, Cross DT, Dacey RG, Zipfel GJ, Kim AH, Uppaluri R, Haughey BH, Tempelhoff R, Rich KM, Schneider J, Chole RA, Chicoine MR
J Neurosurg. 2016 Jan 15; 1-21.

PMID:
    26771847
    [PubMed - as supplied by publisher]
Related citations


Radiation Therapy for Residual or Recurrent Atypical Meningioma: The Effects of Modality, Timing, and Tumor Pathology on Long-Term Outcomes.
Sun SQ, Cai C, Murphy RK, DeWees T, Dacey RG, Grubb RL, Rich KM, Zipfel GJ, Dowling JL, Leuthardt EC, Simpson JR, Robinson CG, Chicoine MR, Perrin RJ, Huang J, Kim AH
Neurosurgery. 2015 Nov 26;

PMID:
    26645969
    [PubMed - as supplied by publisher]
Related citations


Dural arteriovenous fistula-induced thalamic dementia: report of 4 cases.
Holekamp TF, Mollman ME, Murphy RK, Kolar GR, Kramer NM, Derdeyn CP, Moran CJ, Perrin RJ, Rich KM, Lanzino G, Zipfel GJ
J Neurosurg. 2015 Nov 20; 1-14.

PMID:
    26587655
    [PubMed - as supplied by publisher]
Related citations


Hyperventilation, Sympathetic and Metabolic Derangements After Endoscopic Third Ventriculostomy.
Tran L, Athiraman U, Rich KM, Tempelhoff R
J Neurosurg Anesthesiol. 2015 Nov 17;

PMID:
    26580126
    [PubMed - as supplied by publisher]
Related citations


A Gamma-Knife-Enabled Mouse Model of Cerebral Single-Hemisphere Delayed Radiation Necrosis.
Jiang X, Yuan L, Engelbach JA, Cates J, Perez-Torres CJ, Gao F, Thotala D, Drzymala RE, Schmidt RE, Rich KM, Hallahan DE, Ackerman JJ, Garbow JR
PLoS One. 2015; 10(10)e0139596. doi: 10.1371/journal.pone.0139596.

PMID:
    26440791
    [PubMed - in process]
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Aerobic Glycolysis as a Marker of Tumor Aggressiveness: Preliminary Data in High Grade Human Brain Tumors.
Vlassenko AG, McConathy J, Couture LE, Su Y, Massoumzadeh P, Leeds HS, Chicoine MR, Tran DD, Huang J, Dahiya S, Marcus DS, Fouke SJ, Rich KM, Raichle ME, Benzinger TL
Dis Markers. 2015; 2015874904. doi: 10.1155/2015/874904.

PMID:
    26424903
    [PubMed - in process]
Related citations


Utility of Screening for Cerebral Vasospasm Using Digital Subtraction Angiography.
Arias EJ, Vajapey S, Reynolds MR, Chicoine MR, Rich KM, Dacey RG Jr, Dorward IG, Derdeyn CP, Moran CJ, Cross DT 3rd, Zipfel GJ, Dhar R
Stroke. 2015 Nov; 46(11)3137-41. doi: 10.1161/STROKEAHA.115.010081.

PMID:
    26405204
    [PubMed - in process]
Related citations


Specificity of vascular endothelial growth factor treatment for radiation necrosis.
Perez-Torres CJ, Yuan L, Schmidt RE, Rich KM, Drzymala RE, Hallahan DE, Ackerman JJ, Garbow JR
Radiother Oncol. 2015 Nov; 117(2)382-5. doi: 10.1016/j.radonc.2015.09.004.

PMID:
    26376163
    [PubMed - in process]
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A Phase I proof-of-concept and safety trial of sildenafil to treat cerebral vasospasm following subarachnoid hemorrhage.
Washington CW, Derdeyn CP, Dhar R, Arias EJ, Chicoine MR, Cross DT, Dacey RG Jr, Han BH, Moran CJ, Rich KM, Vellimana AK, Zipfel GJ
J Neurosurg. 2016 Feb; 124(2)318-27. doi: 10.3171/2015.2.JNS142752.

PMID:
    26314998
    [PubMed - in process]
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The economic benefits of disease triggered early harvest: A case study of pancreas disease in farmed Atlantic salmon from Norway.
Pettersen JM, Rich KM, Jensen BB, Aunsmo A
Prev Vet Med. 2015 Oct 1; 121(3-4)314-24. doi: 10.1016/j.prevetmed.2015.08.003.

PMID:
    26297077
    [PubMed - in process]
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A CDC20-APC/SOX2 Signaling Axis Regulates Human Glioblastoma Stem-like Cells.
Mao DD, Gujar AD, Mahlokozera T, Chen I, Pan Y, Luo J, Brost T, Thompson EA, Turski A, Leuthardt EC, Dunn GP, Chicoine MR, Rich KM, Dowling JL, Zipfel GJ, Dacey RG, Achilefu S, Tran DD, Yano H, Kim AH
Cell Rep. 2015 Jun 23; 11(11)1809-21. doi: 10.1016/j.celrep.2015.05.027.

PMID:
    26074073
    [PubMed - in process]
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Synthesis, Radiolabeling, and Biological Evaluation of (R)- and (S)-2-Amino-5-[(18)F]fluoro-2-methylpentanoic Acid ((R)-, (S)-[(18)F]FAMPe) as Potential Positron Emission Tomography Tracers for Brain Tumors.
Bouhlel A, Zhou D, Li A, Yuan L, Rich KM, McConathy J
J Med Chem. 2015 May 14; 58(9)3817-29. doi: 10.1021/jm502023y.

PMID:
    25843369
    [PubMed - indexed for MEDLINE]
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Impact of 1p/19q codeletion and histology on outcomes of anaplastic gliomas treated with radiation therapy and temozolomide.
Speirs CK, Simpson JR, Robinson CG, DeWees TA, Tran DD, Linette G, Chicoine MR, Dacey RG, Rich KM, Dowling JL, Leuthardt EC, Zipfel GJ, Kim AH, Huang J
Int J Radiat Oncol Biol Phys. 2015 Feb 1; 91(2)268-76. doi: 10.1016/j.ijrobp.2014.10.027.

PMID:
    25636755
    [PubMed - indexed for MEDLINE]
Related citations


Perilesional edema in radiation necrosis reflects axonal degeneration.
Perez-Torres CJ, Yuan L, Schmidt RE, Rich KM, Ackerman JJ, Garbow JR
Radiat Oncol. 2015 Jan 31; 1033. doi: 10.1186/s13014-015-0335-6.

PMID:
    25636531
    [PubMed - indexed for MEDLINE]
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Comparing routine versus selective use of intraoperative cerebral angiography in aneurysm surgery: a prospective study.
Washington CW, Derdeyn CP, Chicoine MR, Cross DT, Dacey RG, Moran CJ, Rich KM, Zipfel GJ
J Neurointerv Surg. 2016 Jan; 8(1)75-80. doi: 10.1136/neurintsurg-2014-011515.

PMID:
    25423951
    [PubMed - in process]
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Radiation therapy dose escalation for glioblastoma multiforme in the era of temozolomide.
Badiyan SN, Markovina S, Simpson JR, Robinson CG, DeWees T, Tran DD, Linette G, Jalalizadeh R, Dacey R, Rich KM, Chicoine MR, Dowling JL, Leuthardt EC, Zipfel GJ, Kim AH, Huang J
Int J Radiat Oncol Biol Phys. 2014 Nov 15; 90(4)877-85. doi: 10.1016/j.ijrobp.2014.07.014.

PMID:
    25257812
    [PubMed - indexed for MEDLINE]
Related citations


Toward distinguishing recurrent tumor from radiation necrosis: DWI and MTC in a Gamma Knife--irradiated mouse glioma model.
Perez-Torres CJ, Engelbach JA, Cates J, Thotala D, Yuan L, Schmidt RE, Rich KM, Drzymala RE, Ackerman JJ, Garbow JR
Int J Radiat Oncol Biol Phys. 2014 Oct 1; 90(2)446-53. doi: 10.1016/j.ijrobp.2014.06.015.

PMID:
    25104071
    [PubMed - indexed for MEDLINE]
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Predictors of individual tumor local control after stereotactic radiosurgery for non-small cell lung cancer brain metastases.
Garsa AA, Badiyan SN, DeWees T, Simpson JR, Huang J, Drzymala RE, Barani IJ, Dowling JL, Rich KM, Chicoine MR, Kim AH, Leuthardt EC, Robinson CG
Int J Radiat Oncol Biol Phys. 2014 Oct 1; 90(2)407-13. doi: 10.1016/j.ijrobp.2014.05.047.

PMID:
    25084610
    [PubMed - indexed for MEDLINE]
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A GSK-3β inhibitor protects against radiation necrosis in mouse brain.
Jiang X, Perez-Torres CJ, Thotala D, Engelbach JA, Yuan L, Cates J, Gao F, Drzymala RE, Rich KM, Schmidt RE, Ackerman JJ, Hallahan DE, Garbow JR
Int J Radiat Oncol Biol Phys. 2014 Jul 15; 89(4)714-21. doi: 10.1016/j.ijrobp.2014.04.018.

PMID:
    24969790
    [PubMed - indexed for MEDLINE]
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Management of atypical cranial meningiomas, part 2: predictors of progression and the role of adjuvant radiation after subtotal resection.
Sun SQ, Cai C, Murphy RK, DeWees T, Dacey RG, Grubb RL, Rich KM, Zipfel GJ, Dowling JL, Leuthardt EC, Leonard JR, Evans J, Simpson JR, Robinson CG, Perrin RJ, Huang J, Chicoine MR, Kim AH
Neurosurgery. 2014 Oct; 75(4)356-63; discussion 363. doi: 10.1227/NEU.0000000000000462.

PMID:
    24932708
    [PubMed - indexed for MEDLINE]
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