Patient Portal

Keiko Hirose, MD

Professor, Otolaryngology - Head and Neck Surgery
Division Director, Pediatric Otolaryngology

Specialty Areas

Pediatric Otolaryngology
Hearing Loss
Cochlear Implants - Pediatric
Ear, Nose and Throat
Cleft Lip and Palate
Craniofacial Reconstructive Surgery

Board Certifications

Otolaryngology

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Pediatric hearing loss, cochlear implantation, chronic ear surgery, cholesteatoma, conductive hearing loss, aural atresia, BAHA, ear infections, speech disorders, velopharyngeal insufficiency, cleft palate, craniofacial disorders

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Floor: Third Floor
Office Phone: 314-454-6162
Fax: 314-454-2174

Education

Education

Fellowship: Pediatric Otolaryngology, Children's Hospital of Boston, Boston, Massachusetts 2000
Residency: Otolaryngology, University of Washington Medical Center, Seattle, Washington 1999
Medical Degree: Harvard Medical School, Boston, Massachusetts 1993
B.A.: Columbia College, Columbia University, New York 1989

Publication & Research

Publication & Research

Communication pathways to and from the inner ear and their contributions to drug delivery.
Salt AN, Hirose K
Hear Res. 2018 May; 36225-37. doi: 10.1016/j.heares.2017.12.010.

PMID:
    29277248
    [PubMed - in process]
Related citations


Benign Rolandic epilepsy presenting like paradoxical vocal fold motion.
Gross JH, Bertrand M, Hirose K
Int J Pediatr Otorhinolaryngol. 2017 Nov; 102154-156. doi: 10.1016/j.ijporl.2017.09.021.

PMID:
    29106865
    [PubMed - indexed for MEDLINE]
Related citations


Two cell populations participate in clearance of damaged hair cells from the sensory epithelia of the inner ear.
Hirose K, Rutherford MA, Warchol ME
Hear Res. 2017 Sep; 35270-81. doi: 10.1016/j.heares.2017.04.006.

PMID:
    28526177
    [PubMed - indexed for MEDLINE]
Related citations


Infectious complications of pediatric cochlear implants are highly influenced by otitis media.
Vila PM, Ghogomu NT, Odom-John AR, Hullar TE, Hirose K
Int J Pediatr Otorhinolaryngol. 2017 Jun; 9776-82. doi: 10.1016/j.ijporl.2017.02.026.

PMID:
    28483256
    [PubMed - indexed for MEDLINE]
Related citations


Support for the Diagnosis of CHARGE Syndrome-Reply.
Hirose K, Shinawi M
JAMA Otolaryngol Head Neck Surg. 2017 Jun 1; 143(6)635. doi: 10.1001/jamaoto.2016.4765.

PMID:
    28241177
    [PubMed - in process]
Related citations


Prevalence of Semicircular Canal Hypoplasia in Patients With CHARGE Syndrome: 3C Syndrome.
Wineland A, Menezes MD, Shimony JS, Shinawi MS, Hullar TE, Hirose K
JAMA Otolaryngol Head Neck Surg. 2017 Feb 1; 143(2)168-177. doi: 10.1001/jamaoto.2016.3175.

PMID:
    27832265
    [PubMed - indexed for MEDLINE]
Related citations


Fractalkine Signaling Regulates Macrophage Recruitment into the Cochlea and Promotes the Survival of Spiral Ganglion Neurons after Selective Hair Cell Lesion.
Kaur T, Zamani D, Tong L, Rubel EW, Ohlemiller KK, Hirose K, Warchol ME
J Neurosci. 2015 Nov 11; 35(45)15050-61. doi: 10.1523/JNEUROSCI.2325-15.2015.

PMID:
    26558776
    [PubMed - indexed for MEDLINE]
Related citations


Macrophage recruitment and epithelial repair following hair cell injury in the mouse utricle.
Kaur T, Hirose K, Rubel EW, Warchol ME
Front Cell Neurosci. 2015; 9150. doi: 10.3389/fncel.2015.00150.

PMID:
    25954156
    [PubMed]
Related citations


Systemic lipopolysaccharide compromises the blood-labyrinth barrier and increases entry of serum fluorescein into the perilymph.
Hirose K, Hartsock JJ, Johnson S, Santi P, Salt AN
J Assoc Res Otolaryngol. 2014 Oct; 15(5)707-19. doi: 10.1007/s10162-014-0476-6.

PMID:
    24952083
    [PubMed - indexed for MEDLINE]
Related citations


Systemic lipopolysaccharide induces cochlear inflammation and exacerbates the synergistic ototoxicity of kanamycin and furosemide.
Hirose K, Li SZ, Ohlemiller KK, Ransohoff RM
J Assoc Res Otolaryngol. 2014 Aug; 15(4)555-70. doi: 10.1007/s10162-014-0458-8.

PMID:
    24845404
    [PubMed - indexed for MEDLINE]
Related citations


Tolosa-Hunt syndrome masquerading as Gradenigo syndrome in a teenager.
Slattery E, White AJ, Gauthier M, Linscott L, Hirose K
Int J Pediatr Otorhinolaryngol. 2013 Jul; 77(7)1219-21. doi: 10.1016/j.ijporl.2013.04.023.

PMID:
    23684166
    [PubMed - indexed for MEDLINE]
Related citations


Depletion of resident macrophages does not alter sensory regeneration in the avian cochlea.
Warchol ME, Schwendener RA, Hirose K
PLoS One. 2012; 7(12)e51574. doi: 10.1371/journal.pone.0051574.

PMID:
    23240046
    [PubMed - indexed for MEDLINE]
Related citations


Comparative analysis of combination kanamycin-furosemide versus kanamycin alone in the mouse cochlea.
Hirose K, Sato E
Hear Res. 2011 Feb; 272(1-2)108-16. doi: 10.1016/j.heares.2010.10.011.

PMID:
    21044672
    [PubMed - indexed for MEDLINE]
Related citations


Expression of fractalkine receptor CX3CR1 on cochlear macrophages influences survival of hair cells following ototoxic injury.
Sato E, Shick HE, Ransohoff RM, Hirose K
J Assoc Res Otolaryngol. 2010 Jun; 11(2)223-34. doi: 10.1007/s10162-009-0198-3.

PMID:
    19936834
    [PubMed - indexed for MEDLINE]
Related citations


Nonsteroidal anti-inflammatory drugs and postoperative bleeding following adenotonsillectomy in pediatric patients.
Jeyakumar A, Brickman TM, Williamson ME, Hirose K, Krakovitz P, Whittemore K, Discolo C
Arch Otolaryngol Head Neck Surg. 2008 Jan; 134(1)24-7. doi: 10.1001/archoto.2007.11.

PMID:
    18209131
    [PubMed - indexed for MEDLINE]
Related citations


Safety and efficacy of powered intracapsular tonsillectomy in children: a multi-center retrospective case series.
Solares CA, Koempel JA, Hirose K, Abelson TI, Reilly JS, Cook SP, April MM, Ward RF, Bent JP 3rd, Xu M, Koltai PJ
Int J Pediatr Otorhinolaryngol. 2005 Jan; 69(1)21-6.

PMID:
    15627442
    [PubMed - indexed for MEDLINE]
Related citations


Starplasty: revisiting a pediatric tracheostomy technique.
Solares CA, Krakovitz P, Hirose K, Koltai PJ
Otolaryngol Head Neck Surg. 2004 Nov; 131(5)717-22.

PMID:
    15523453
    [PubMed - indexed for MEDLINE]
Related citations


Electron microscopy of degenerative changes in the chick basilar papilla after gentamicin exposure.
Hirose K, Westrum LE, Cunningham DE, Rubel EW
J Comp Neurol. 2004 Mar 1; 470(2)164-80.

PMID:
    14750159
    [PubMed - indexed for MEDLINE]
Related citations


Lateral wall histopathology and endocochlear potential in the noise-damaged mouse cochlea.
Hirose K, Liberman MC
J Assoc Res Otolaryngol. 2003 Sep; 4(3)339-52.

PMID:
    14690052
    [PubMed - indexed for MEDLINE]
Related citations


Intracapsular tonsillar reduction (partial tonsillectomy): reviving a historical procedure for obstructive sleep disordered breathing in children.
Koltai PJ, Solares CA, Koempel JA, Hirose K, Abelson TI, Krakovitz PR, Chan J, Xu M, Mascha EJ
Otolaryngol Head Neck Surg. 2003 Nov; 129(5)532-8.

PMID:
    14595276
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Cochlear inflammation and mononuclear phagocytes in repair of the damaged cochlea.