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Katherine P. Ponder, MD

Professor, Medicine
Division of Hematology
Professor, Biochemistry and Molecular Biophysics

Specialty Areas

Hematology

Board Certifications

Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Hematology, gene therapy, hemophilia, liver function

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Barnes-Jewish Hospital (South)
Barnard Cancer Center

4960 Children's Place
St. Louis, MO 63110

Suite: Wohl Hospital, 4th Floor
Office Phone: 314-362-7578
Fax: 314-362-1608

Education

Education

Postdoctoral Assoc.: Cell Biology, Baylor College of Medicine, Houston, Texas 1990
Postdoctoral Assoc.: Molecular Biophysics, Yale University, New Haven, Connecticut 1988
Residency: Internal Medicine, Parkland Hospital, Dallas, Texas 1985
Medical School: Washington University School of Medicine, St. Louis, Missouri 1983
B.S.: Stanford University, Stanford, California 1979

Publication & Research

Publication & Research

Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII.
Gurda BL, De Guilhem De Lataillade A, Bell P, Zhu Y, Yu H, Wang P, Bagel J, Vite CH, Sikora T, Hinderer C, Calcedo R, Yox AD, Steet RA, Ruane T, O'Donnell P, Gao G, Wilson JM, Casal M, Ponder KP, Haskins ME
Mol Ther. 2016 Feb; 24(2)206-216. doi: 10.1038/mt.2015.189.

PMID:
    26447927
    [PubMed - indexed for MEDLINE]
Related citations


A review of gene therapy in canine and feline models of lysosomal storage disorders.
Bradbury AM, Gurda BL, Casal ML, Ponder KP, Vite CH, Haskins ME
Hum Gene Ther Clin Dev. 2015 Mar; 26(1)27-37. doi: 10.1089/humc.2015.002.

PMID:
    25671613
    [PubMed - indexed for MEDLINE]
Related citations


The effect of Tlr4 and/or C3 deficiency and of neonatal gene therapy on skeletal disease in mucopolysaccharidosis VII mice.
Xing EM, Wu S, Ponder KP
Mol Genet Metab. 2015 Feb; 114(2)209-16. doi: 10.1016/j.ymgme.2014.12.305.

PMID:
    25559179
    [PubMed - indexed for MEDLINE]
Related citations


Effects of neonatal enzyme replacement therapy and simvastatin treatment on cervical spine disease in mucopolysaccharidosis I dogs.
Chiaro JA, O'Donnell P, Shore EM, Malhotra NR, Ponder KP, Haskins ME, Smith LJ
J Bone Miner Res. 2014 Dec; 29(12)2610-7. doi: 10.1002/jbmr.2290.

PMID:
    24898323
    [PubMed - indexed for MEDLINE]
Related citations


The effect of neonatal gene therapy with a gamma retroviral vector on cardiac valve disease in mucopolysaccharidosis VII dogs after a decade.
Bigg PW, Sleeper MM, O'Donnell PA, Liu Y, Wu S, Casal ML, Haskins ME, Ponder KP
Mol Genet Metab. 2013 Nov; 110(3)311-8. doi: 10.1016/j.ymgme.2013.06.015.

PMID:
    23860311
    [PubMed - indexed for MEDLINE]
Related citations


Pathogenesis of mitral valve disease in mucopolysaccharidosis VII dogs.
Bigg PW, Baldo G, Sleeper MM, O'Donnell PA, Bai H, Rokkam VR, Liu Y, Wu S, Giugliani R, Casal ML, Haskins ME, Ponder KP
Mol Genet Metab. 2013 Nov; 110(3)319-28. doi: 10.1016/j.ymgme.2013.06.013.

PMID:
    23856419
    [PubMed - indexed for MEDLINE]
Related citations


The effect of neonatal gene therapy on skeletal manifestations in mucopolysaccharidosis VII dogs after a decade.
Xing EM, Knox VW, O'Donnell PA, Sikura T, Liu Y, Wu S, Casal ML, Haskins ME, Ponder KP
Mol Genet Metab. 2013 Jun; 109(2)183-93. doi: 10.1016/j.ymgme.2013.03.013.

PMID:
    23628461
    [PubMed - indexed for MEDLINE]
Related citations


Their Just Rewards: Acknowledging Key Contributions of Society Members.
Ponder KP
Mol Ther. 2013 May; 21(5)915-916. doi: 10.1038/mt.2013.72.

PMID:
    28178546
    [PubMed]
Related citations


Postnatal progression of bone disease in the cervical spines of mucopolysaccharidosis I dogs.
Chiaro JA, Baron MD, Del Alcazar CM, O'Donnell P, Shore EM, Elliott DM, Ponder KP, Haskins ME, Smith LJ
Bone. 2013 Jul; 55(1)78-83. doi: 10.1016/j.bone.2013.03.014.

PMID:
    23563357
    [PubMed - indexed for MEDLINE]
Related citations


Retroviral-vector-mediated gene therapy to mucopolysaccharidosis I mice improves sensorimotor impairments and other behavioral deficits.
Baldo G, Wozniak DF, Ohlemiller KK, Zhang Y, Giugliani R, Ponder KP
J Inherit Metab Dis. 2013 May; 36(3)499-512. doi: 10.1007/s10545-012-9530-x.

PMID:
    22983812
    [PubMed - indexed for MEDLINE]
Related citations


Evidence of a progressive motor dysfunction in Mucopolysaccharidosis type I mice.
Baldo G, Mayer FQ, Martinelli B, Dilda A, Meyer F, Ponder KP, Giugliani R, Matte U
Behav Brain Res. 2012 Jul 15; 233(1)169-75. doi: 10.1016/j.bbr.2012.04.051.

PMID:
    22580166
    [PubMed - indexed for MEDLINE]
Related citations


Pathogenesis of lumbar spine disease in mucopolysaccharidosis VII.
Smith LJ, Baldo G, Wu S, Liu Y, Whyte MP, Giugliani R, Elliott DM, Haskins ME, Ponder KP
Mol Genet Metab. 2012 Sep; 107(1-2)153-60. doi: 10.1016/j.ymgme.2012.03.014.

PMID:
    22513347
    [PubMed - indexed for MEDLINE]
Related citations


Effect of neonatal gene therapy on lumbar spine disease in mucopolysaccharidosis VII dogs.
Smith LJ, Martin JT, O'Donnell P, Wang P, Elliott DM, Haskins ME, Ponder KP
Mol Genet Metab. 2012 Sep; 107(1-2)145-52. doi: 10.1016/j.ymgme.2012.03.013.

PMID:
    22510705
    [PubMed - indexed for MEDLINE]
Related citations


Neonatal gene therapy with a gamma retroviral vector in mucopolysaccharidosis VI cats.
Ponder KP, O'Malley TM, Wang P, O'Donnell PA, Traas AM, Knox VW, Aguirre GA, Ellinwood NM, Metcalf JA, Wang B, Parkinson-Lawrence EJ, Sleeper MM, Brooks DA, Hopwood JJ, Haskins ME
Mol Ther. 2012 May; 20(5)898-907. doi: 10.1038/mt.2012.9.

PMID:
    22395531
    [PubMed - indexed for MEDLINE]
Related citations


FIXing factor VIII inhibitors.
Ponder KP
Blood. 2012 Jan 12; 119(2)325-6. doi: 10.1182/blood-2011-11-389486.

PMID:
    22247519
    [PubMed - indexed for MEDLINE]
Related citations


Merry christmas for patients with hemophilia B.
Ponder KP
N Engl J Med. 2011 Dec 22; 365(25)2424-5. doi: 10.1056/NEJMe1111138.

PMID:
    22149960
    [PubMed - indexed for MEDLINE]
Related citations


Pathogenesis of aortic dilatation in mucopolysaccharidosis VII mice may involve complement activation.
Baldo G, Wu S, Howe RA, Ramamoothy M, Knutsen RH, Fang J, Mecham RP, Liu Y, Wu X, Atkinson JP, Ponder KP
Mol Genet Metab. 2011 Dec; 104(4)608-19. doi: 10.1016/j.ymgme.2011.08.018.

PMID:
    21944884
    [PubMed - indexed for MEDLINE]
Related citations


Cardiac disease in patients with mucopolysaccharidosis: presentation, diagnosis and management.
Braunlin EA, Harmatz PR, Scarpa M, Furlanetto B, Kampmann C, Loehr JP, Ponder KP, Roberts WC, Rosenfeld HM, Giugliani R
J Inherit Metab Dis. 2011 Dec; 34(6)1183-97. doi: 10.1007/s10545-011-9359-8.

PMID:
    21744090
    [PubMed - indexed for MEDLINE]
Related citations


Status of therapeutic gene transfer to treat cardiovascular disease in dogs and cats.
Sleeper M, Bish LT, Haskins M, Ponder KP, Sweeney HL
J Vet Cardiol. 2011 Jun; 13(2)131-40. doi: 10.1016/j.jvc.2011.04.001.

PMID:
    21640678
    [PubMed - indexed for MEDLINE]
Related citations


Hemophilia gene therapy: a Holy Grail found.
Ponder KP
Mol Ther. 2011 Mar; 19(3)427-8. doi: 10.1038/mt.2011.13.

PMID:
    21358702
    [PubMed - indexed for MEDLINE]
Related citations