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Karl W. Staser, MD, PhD

Instructor, Medicine
Division of Dermatology

Specialty Areas

Dermatology

Board Certifications

Dermatology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Skin disease in patients with cancer, bone marrow and organ transplantation, cutaneous lymphoma, leukemia and/or graft-versus-host disease.

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Barnes-Jewish Center for Outpatient Health

4901 Forest Park Avenue
St. Louis, MO 63108

Suite: 502
Floor: 5
Office Phone: 314-362-2643
Fax: 314-747-8693

Education

Education

Residency, Dermatology: Barnes-Jewish Hospital, St. Louis, MO 2017
PhD, Biochemistry: Indiana University School of Medicine, Indianapolis, IN 2013
Medical Degree: Indiana University School fo Medicine, Indianapolis, IN 2013
AB, American History and Literature: Harvard College, Cambridge, MA 2002

Publication & Research

Publication & Research

An "off-the-shelf" fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies.
Cooper ML, Choi J, Staser K, Ritchey JK, Devenport JM, Eckardt K, Rettig MP, Wang B, Eissenberg LG, Ghobadi A, Gehrs LN, Prior JL, Achilefu S, Miller CA, Fronick CC, O'Neal J, Gao F, Weinstock DM, Gutierrez A, Fulton RS, DiPersio JF
Leukemia. 2018 Feb 20; doi: 10.1038/s41375-018-0065-5.

PMID:
    29483708
    [PubMed - as supplied by publisher]
Related citations


The Role of Janus Kinase Signaling in Graft-Versus-Host Disease and Graft Versus Leukemia.
Schroeder MA, Choi J, Staser K, DiPersio JF
Biol Blood Marrow Transplant. 2017 Dec 28; pii: S1083-8791(17)31829-3. doi: 10.1016/j.bbmt.2017.12.797.

PMID:
    29289756
    [PubMed - as supplied by publisher]
Related citations


OMIP-042: 21-color flow cytometry to comprehensively immunophenotype major lymphocyte and myeloid subsets in human peripheral blood.
Staser KW, Eades W, Choi J, Karpova D, DiPersio JF
Cytometry A. 2018 Feb; 93(2)186-189. doi: 10.1002/cyto.a.23303.

PMID:
    29288606
    [PubMed - in process]
Related citations


Injection-Site Cutaneous Pseudolymphoma Induced by a GM-CSF-Producing Tumor Cell Vaccine.
Staser K, Abner S, Anadkat M, Musiek A, Schaffer A
JAMA Dermatol. 2017 Apr 1; 153(4)332-334. doi: 10.1001/jamadermatol.2016.4988.

PMID:
    28114617
    [PubMed - in process]
Related citations


Pleomorphic soft tissue sarcoma metastatic to the skin of the scalp and groin.
Staser K, Mount CE 3rd, Solus J, Musiek A
JAAD Case Rep. 2015 Mar; 1(2)96-8. doi: 10.1016/j.jdcr.2015.02.005.

PMID:
    27051696
    [PubMed]
Related citations


Nf1 Haploinsufficiency Alters Myeloid Lineage Commitment and Function, Leading to Deranged Skeletal Homeostasis.
Rhodes SD, Yang H, Dong R, Menon K, He Y, Li Z, Chen S, Staser KW, Jiang L, Wu X, Yang X, Peng X, Mohammad KS, Guise TA, Xu M, Yang FC
J Bone Miner Res. 2015 Oct; 30(10)1840-51. doi: 10.1002/jbmr.2538.

PMID:
    25917016
    [PubMed - indexed for MEDLINE]
Related citations


Pak2 regulates hematopoietic progenitor cell proliferation, survival, and differentiation.
Zeng Y, Broxmeyer HE, Staser K, Chitteti BR, Park SJ, Hahn S, Cooper S, Sun Z, Jiang L, Yang X, Yuan J, Kosoff R, Sandusky G, Srour EF, Chernoff J, Clapp DW
Stem Cells. 2015 May; 33(5)1630-41. doi: 10.1002/stem.1951.

PMID:
    25586960
    [PubMed - indexed for MEDLINE]
Related citations


A murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formation.
Gehlhausen JR, Park SJ, Hickox AE, Shew M, Staser K, Rhodes SD, Menon K, Lajiness JD, Mwanthi M, Yang X, Yuan J, Territo P, Hutchins G, Nalepa G, Yang FC, Conway SJ, Heinz MG, Stemmer-Rachamimov A, Yates CW, Wade Clapp D
Hum Mol Genet. 2015 Jan 1; 24(1)1-8. doi: 10.1093/hmg/ddu414.

PMID:
    25113746
    [PubMed - indexed for MEDLINE]
Related citations


The beak sign: a clinical clue to airborne contact dermatitis.
Staser K, Ezra N, Sheehan MP, Mousdicas N
Dermatitis. 2014 Mar-Apr; 25(2)97-8. doi: 10.1097/DER.0b013e3182a8ada3.

PMID:
    24603523
    [PubMed - indexed for MEDLINE]
Related citations


Hyperactive transforming growth factor-β1 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model.
Rhodes SD, Wu X, He Y, Chen S, Yang H, Staser KW, Wang J, Zhang P, Jiang C, Yokota H, Dong R, Peng X, Yang X, Murthy S, Azhar M, Mohammad KS, Xu M, Guise TA, Yang FC
J Bone Miner Res. 2013 Dec; 28(12)2476-89. doi: 10.1002/jbmr.1992.

PMID:
    23703870
    [PubMed - indexed for MEDLINE]
Related citations


Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk.
Staser K, Park SJ, Rhodes SD, Zeng Y, He YZ, Shew MA, Gehlhausen JR, Cerabona D, Menon K, Chen S, Sun Z, Yuan J, Ingram DA, Nalepa G, Yang FC, Clapp DW
J Clin Invest. 2013 Jan; 123(1)329-34. doi: 10.1172/JCI66167.

PMID:
    23221339
    [PubMed - indexed for MEDLINE]
Related citations


Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial.
Robertson KA, Nalepa G, Yang FC, Bowers DC, Ho CY, Hutchins GD, Croop JM, Vik TA, Denne SC, Parada LF, Hingtgen CM, Walsh LE, Yu M, Pradhan KR, Edwards-Brown MK, Cohen MD, Fletcher JW, Travers JB, Staser KW, Lee MW, Sherman MR, Davis CJ, Miller LC, Ingram DA, Clapp DW
Lancet Oncol. 2012 Dec; 13(12)1218-24. doi: 10.1016/S1470-2045(12)70414-X.

PMID:
    23099009
    [PubMed - indexed for MEDLINE]
Related citations


A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells.
Staser K, Shew MA, Michels EG, Mwanthi MM, Yang FC, Clapp DW, Park SJ
Exp Hematol. 2013 Jan; 41(1)56-66.e2. doi: 10.1016/j.exphem.2012.10.001.

PMID:
    23063725
    [PubMed - indexed for MEDLINE]
Related citations


The plexiform neurofibroma microenvironment.
Yang FC, Staser K, Clapp DW
Cancer Microenviron. 2012 Dec; 5(3)307-10. doi: 10.1007/s12307-012-0115-x.

PMID:
    22821631
    [PubMed]
Related citations


Identification of molecular compartments and genetic circuitry in the developing mammalian kidney.
Yu J, Valerius MT, Duah M, Staser K, Hansard JK, Guo JJ, McMahon J, Vaughan J, Faria D, Georgas K, Rumballe B, Ren Q, Krautzberger AM, Junker JP, Thiagarajan RD, Machanick P, Gray PA, van Oudenaarden A, Rowitch DH, Stiles CD, Ma Q, Grimmond SM, Bailey TL, Little MH, McMahon AP
Development. 2012 May; 139(10)1863-73. doi: 10.1242/dev.074005.

PMID:
    22510988
    [PubMed - indexed for MEDLINE]
Related citations


Pathogenesis of plexiform neurofibroma: tumor-stromal/hematopoietic interactions in tumor progression.
Staser K, Yang FC, Clapp DW
Annu Rev Pathol. 2012; 7469-95. doi: 10.1146/annurev-pathol-011811-132441.

PMID:
    22077553
    [PubMed - indexed for MEDLINE]
Related citations


Erk1 positively regulates osteoclast differentiation and bone resorptive activity.
He Y, Staser K, Rhodes SD, Liu Y, Wu X, Park SJ, Yuan J, Yang X, Li X, Jiang L, Chen S, Yang FC
PLoS One. 2011; 6(9)e24780. doi: 10.1371/journal.pone.0024780.

PMID:
    21961044
    [PubMed - indexed for MEDLINE]
Related citations


Kinase suppressor of Ras (KSR1) modulates multiple kit-ligand-dependent mast cell functions.
Chen M, Burgin S, Staser K, He Y, Li X, Robinson M, Jiang L, Chan RJ, Ingram D, Clapp DW
Exp Hematol. 2011 Oct; 39(10)969-76. doi: 10.1016/j.exphem.2011.06.009.

PMID:
    21726514
    [PubMed - indexed for MEDLINE]
Related citations


Dietary behaviors associated with fruit and vegetable consumption, Marion County, Indiana, 2005.
Staser KW, Zollinger TW, Saywell RM Jr, Kunapareddy S, Gibson PJ, Caine VA
Prev Chronic Dis. 2011 May; 8(3)A66.

PMID:
    21477506
    [PubMed - indexed for MEDLINE]
Related citations


Multiple increased osteoclast functions in individuals with neurofibromatosis type 1.
Stevenson DA, Yan J, He Y, Li H, Liu Y, Zhang Q, Jing Y, Guo Z, Zhang W, Yang D, Wu X, Hanson H, Li X, Staser K, Viskochil DH, Carey JC, Chen S, Miller L, Roberson K, Moyer-Mileur L, Yu M, Schwarz EL, Pasquali M, Yang FC
Am J Med Genet A. 2011 May; 155A(5)1050-9. doi: 10.1002/ajmg.a.33965.

PMID:
    21465658
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Novel therapies for preventing and treating graft-versus-host disease, for improving solid organ transplantation and for treating cutaneous lymphoma.