Patient Portal

Kalen R. Dionne, MD, PhD

Instructor, Neurology

Specialty Areas

Neurology - Adult
Neurology - General
Headache Disorders

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Seizures, headaches, paraneoplastic diseases, neurologic complications of cancer

  • Location(s)
  • Education
  • Publication & Research

Location(s)

Location(s)

Center for Advanced Medicine
Neuroscience Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: 314-362-7241
Fax: 314-362-0388

Education

Education

Residency: Neurology: Barnes-Jewish Hospital/Washington University School of Medicine in St. Louis, St. Louis, MO 2019
Medical Degree: University of Colorado Anschutz Medical Campus, Aurora, CO 2015
PhD: Neuroscience: University of Colorado Anschutz Medical Campus, Aurora, CO 2012
Bachelor of Arts: Neuroscience: Colorado College, Colorado Springs, CO 2005

Publication & Research

Publication & Research

Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies.
Fadlullah MZ, Chiang IK, Dionne KR, Yee PS, Gan CP, Sam KK, Tiong KH, Ng AK, Martin D, Lim KP, Kallarakkal TG, Mustafa WM, Lau SH, Abraham MT, Zain RB, Rahman ZA, Molinolo A, Patel V, Gutkind JS, Tan AC, Cheong SC
Oncotarget. 2016 May 10; 7(19)27802-18. doi: 10.18632/oncotarget.8533.

PMID:
    27050151
    [PubMed - indexed for MEDLINE]
Related citations


Potentially malignant disorders of the oral cavity: current practice and future directions in the clinic and laboratory.
Dionne KR, Warnakulasuriya S, Zain RB, Cheong SC
Int J Cancer. 2015 Feb 1; 136(3)503-15. doi: 10.1002/ijc.28754.

PMID:
    24482244
    [PubMed - indexed for MEDLINE]
Related citations


Death receptor-mediated apoptotic signaling is activated in the brain following infection with West Nile virus in the absence of a peripheral immune response.
Clarke P, Leser JS, Quick ED, Dionne KR, Beckham JD, Tyler KL
J Virol. 2014 Jan; 88(2)1080-9. doi: 10.1128/JVI.02944-13.

PMID:
    24198425
    [PubMed - indexed for MEDLINE]
Related citations


Slice culture modeling of central nervous system (CNS) viral infection.
Dionne KR, Tyler KL
Methods Mol Biol. 2013; 107897-117. doi: 10.1007/978-1-62703-640-5_9.

PMID:
    23975824
    [PubMed - indexed for MEDLINE]
Related citations


Gefitinib selectively inhibits tumor cell migration in EGFR-amplified human glioblastoma.
Parker JJ, Dionne KR, Massarwa R, Klaassen M, Foreman NK, Niswander L, Canoll P, Kleinschmidt-Demasters BK, Waziri A
Neuro Oncol. 2013 Aug; 15(8)1048-57. doi: 10.1093/neuonc/not053.

PMID:
    23749785
    [PubMed - indexed for MEDLINE]
Related citations


Daxx upregulation within the cytoplasm of reovirus-infected cells is mediated by interferon and contributes to apoptosis.
Dionne KR, Zhuang Y, Leser JS, Tyler KL, Clarke P
J Virol. 2013 Mar; 87(6)3447-60. doi: 10.1128/JVI.02324-12.

PMID:
    23302889
    [PubMed - indexed for MEDLINE]
Related citations


Activation of innate immune responses in the central nervous system during reovirus myelitis.
Schittone SA, Dionne KR, Tyler KL, Clarke P
J Virol. 2012 Aug; 86(15)8107-18. doi: 10.1128/JVI.00171-12.

PMID:
    22623770
    [PubMed - indexed for MEDLINE]
Related citations


Type I interferon signaling limits reoviral tropism within the brain and prevents lethal systemic infection.
Dionne KR, Galvin JM, Schittone SA, Clarke P, Tyler KL
J Neurovirol. 2011 Aug; 17(4)314-26. doi: 10.1007/s13365-011-0038-1.

PMID:
    21671121
    [PubMed - indexed for MEDLINE]
Related citations


A brain slice culture model of viral encephalitis reveals an innate CNS cytokine response profile and the therapeutic potential of caspase inhibition.
Dionne KR, Leser JS, Lorenzen KA, Beckham JD, Tyler KL
Exp Neurol. 2011 Apr; 228(2)222-31. doi: 10.1016/j.expneurol.2011.01.006.

PMID:
    21241693
    [PubMed - indexed for MEDLINE]
Related citations


Three ubiquitin conjugation sites in the amino terminus of the dopamine transporter mediate protein kinase C-dependent endocytosis of the transporter.
Miranda M, Dionne KR, Sorkina T, Sorkin A
Mol Biol Cell. 2007 Jan; 18(1)313-23.

PMID:
    17079728
    [PubMed - indexed for MEDLINE]
Related citations


RNA interference screen reveals an essential role of Nedd4-2 in dopamine transporter ubiquitination and endocytosis.
Sorkina T, Miranda M, Dionne KR, Hoover BR, Zahniser NR, Sorkin A
J Neurosci. 2006 Aug 2; 26(31)8195-205.

PMID:
    16885233
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Application of nanotechnology to the diagnosis and treatment of neurologic diseases. Development of novel neurodiagnostics and neurotherapeutics.