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Joshua W. Osbun, MD

Assistant Professor, Neurological Surgery
Assistant Professor, Radiology
Assistant Professor, Neurology

Specialty Areas

Neurosurgery
Neurovascular Disorders
Aneurysms and Vascular Malformations
Aneurysms
Arteriovenus Malformation
Carotid Disease
Cerebrovascular Disease

Hospital Affiliations

Barnes-Jewish Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Open surgical and endovascular treatment of cerebrovascular disease and complex tumors of the skull base. special expertise in clipping, coiling and flow diversion for brain aneurysms, surgical resection and embolization of brain arteriovenous malformations and dural arteriovenous fistulas, the surgical treatment of cavernous malformation, meningioma, and moya-moya disease, carotid stenting and carotid endarterectomy for carotid artery stenosis, and mechanical thrombectomy for acute ischemic stroke

  • Location(s)
  • Education
  • Publication & Research
  • In the News
  • Videos

Location(s)

Location(s)

Center for Advanced Medicine
Neuroscience Center

4921 Parkview Place
St. Louis, MO 63110

Office Phone: 314-362-3577

Education

Education

Fellowship: Cerebrovascular & Interventional Neuroradiology, Emory University, Atlanta, Georgia, 2016
Specialist Registrar in Neurosurgery: Atkinson Morley & St. George’s Hospital, London, United Kingdom, 2011
Residency: Neurological Surgery, University of Washington, Seattle, Washington, 2014
Medical Degree: University of Texas Southwestern Medical Center, Dallas, Texas, 2007
Bachelor of Arts: Texas A & M University, College Station, Texas, 2002

Publication & Research

Publication & Research

Phosphoproteomic and Kinomic Signature of Clinically Aggressive Grade I (1.5) Meningiomas Reveals Rb1 signaling as a Novel Mediator and Biomarker.
Parada CA, Osbun JW, Busald T, Karasozen Y, Kaur S, Shi M, Barber J, Adidharma W, Cimino PJ, Pan C, Gonzalez-Cuyar LF, Rostomily R, Born DE, Zhang J, Ferreira M
Clin Cancer Res. 2019 Oct 15; pii: clincanres.0641.2018. doi: 10.1158/1078-0432.CCR-18-0641.

PMID:
    31615938
    [PubMed - as supplied by publisher]
Related citations


Transradial intraoperative cerebral angiography: a multicenter case series and technical report.
Osbun JW, Patel B, Levitt MR, Yahanda AT, Shah A, Dlouhy KM, Thatcher JP, Chicoine MR, Kim LJ, Zipfel GJ
J Neurointerv Surg. 2019 Sep 4; pii: neurintsurg-2019-015207. doi: 10.1136/neurintsurg-2019-015207.

PMID:
    31484699
    [PubMed - as supplied by publisher]
Related citations


Predictors of preoperative endovascular embolization of meningiomas: subanalysis of anatomic location and arterial supply.
Barros G, Feroze AH, Sen R, Kelly CM, Barber J, Hallam DK, Ghodke B, Osbun JW, Kim LJ, Levitt MR
J Neurointerv Surg. 2019 Jul 15; pii: neurintsurg-2019-015129. doi: 10.1136/neurintsurg-2019-015129.

PMID:
    31308198
    [PubMed - as supplied by publisher]
Related citations


Evidence for a conditioning effect of inhalational anesthetics on angiographic vasospasm after aneurysmal subarachnoid hemorrhage.
Athiraman U, Aum D, Vellimana AK, Osbun JW, Dhar R, Tempelhoff R, Zipfel GJ
J Neurosurg. 2019 Jun 14; 1-7. doi: 10.3171/2019.3.JNS183512.

PMID:
    31200380
    [PubMed - as supplied by publisher]
Related citations


Somatic PDGFRB Activating Variants in Fusiform Cerebral Aneurysms.
Karasozen Y, Osbun JW, Parada CA, Busald T, Tatman P, Gonzalez-Cuyar LF, Hale CJ, Alcantara D, O'Driscoll M, Dobyns WB, Murray M, Kim LJ, Byers P, Dorschner MO, Ferreira M Jr
Am J Hum Genet. 2019 May 2; 104(5)968-976. doi: 10.1016/j.ajhg.2019.03.014.

PMID:
    31031011
    [PubMed - in process]
Related citations


Impact of aneurysm morphology on safety and effectiveness of flow diverter treatment of vertebrobasilar aneurysms.
Wallace AN, CreveCoeur TS, Grossberg JA, Kamran M, Osbun JW, Delgado Almandoz JE, Kayan Y, Cross DT, Moran CJ
J Neuroradiol. 2019 Nov; 46(6)401-410. doi: 10.1016/j.neurad.2019.02.003.

PMID:
    30857898
    [PubMed - in process]
Related citations


Transradial approach for flow diversion treatment of cerebral aneurysms: a multicenter study.
Chen SH, Snelling BM, Shah SS, Sur S, Brunet MC, Starke RM, Yavagal DR, Osbun JW, Peterson EC
J Neurointerv Surg. 2019 Aug; 11(8)796-800. doi: 10.1136/neurintsurg-2018-014620.

PMID:
    30670622
    [PubMed - in process]
Related citations


Pipeline Embolization of Vertebrobasilar Aneurysms-A Multicenter Case Series.
Wallace AN, Madaelil TP, Kamran M, Miller TR, Delgado Almandoz JE, Grossberg JA, Kansagra AP, Gandhi D, Kayan Y, Cawley CM, Moran CJ, Jindal G, CreveCoeur T, Howard BM, Cross DT, Kole MJ, Roy AK, Dion JE, Osbun JW
World Neurosurg. 2019 Jan 3; pii: S1878-8750(18)32939-5. doi: 10.1016/j.wneu.2018.12.116.

PMID:
    30610980
    [PubMed - as supplied by publisher]
Related citations


Treatment of pediatric intracranial aneurysms: case series and meta-analysis.
Yasin JT, Wallace AN, Madaelil TP, Osbun JW, Moran CJ, Cross DT, Limbrick DD, Zipfel GJ, Dacey RG, Kansagra AP
J Neurointerv Surg. 2019 Mar; 11(3)257-264. doi: 10.1136/neurintsurg-2018-014001.

PMID:
    30100557
    [PubMed - indexed for MEDLINE]
Related citations


Endovascular Treatment of Posterior Inferior Cerebellar Artery Aneurysms with Flow Diversion.
Wallace AN, Kamran M, Madaelil TP, Kayan Y, Osbun JW, Roy AK, Almandoz JED, Moran CJ, Howard BM, Yasin J, Grossberg JA
World Neurosurg. 2018 Jun; 114e581-e587. doi: 10.1016/j.wneu.2018.03.036.

PMID:
    29548957
    [PubMed - indexed for MEDLINE]
Related citations


Endovascular Treatment of Posterior Cerebral Artery Aneurysms With Flow Diversion: Case Series and Systematic Review.
Wallace AN, Grossberg JA, Almandoz JED, Kamran M, Roy AK, Kayan Y, Austin MJ, Howard BM, Moran CJ, Cawley CM, Cross DT, Dion JE, Kansagra AP, Osbun JW
Neurosurgery. 2018 Oct 1; 83(4)790-799. doi: 10.1093/neuros/nyx561.

PMID:
    29528441
    [PubMed - indexed for MEDLINE]
Related citations


Direct puncture Onyx embolization of a large calvarial metastasis with intracranial extension: Case report.
Zhou MH, Dunn GP, Osbun JW, Cross DT 3rd, Moran CJ, Dacey RG Jr, Kansagra AP
Interv Neuroradiol. 2018 Apr; 24(2)220-224. doi: 10.1177/1591019917740353.

PMID:
    29119877
    [PubMed - indexed for MEDLINE]
Related citations


Isolated Internal Carotid Artery Thrombus and Cerebral Infarction in a Patient with Necrotizing Pancreatitis: Case Report.
Ludwig DR, Austin MJ, Wallace AN, Kamran M, Kansagra AP, Osbun JW, Cross DT, Moran CJ
J Stroke Cerebrovasc Dis. 2018 Jan; 27(1)e1-e4. doi: 10.1016/j.jstrokecerebrovasdis.2017.08.012.

PMID:
    28893576
    [PubMed - indexed for MEDLINE]
Related citations


Comparative Proteomic Profiling Using Two-Dimensional Gel Electrophoresis and Identification via LC-MS/MS Reveals Novel Protein Biomarkers to Identify Aggressive Subtypes of WHO Grade I Meningioma.
Osbun JW, Tatman PD, Kaur S, Parada C, Busald T, Gonzalez-Cuyar L, Shi M, Born DE, Zhang J, Ferreira M
J Neurol Surg B Skull Base. 2017 Oct; 78(5)371-379. doi: 10.1055/s-0037-1601889.

PMID:
    28875114
    [PubMed]
Related citations


Pipeline embolization of posterior communicating artery aneurysms associated with a fetal origin posterior cerebral artery.
Wallace AN, Kayan Y, Austin MJ, Delgado Almandoz JE, Kamran M, Cross DT 3rd, Moran CJ, Osbun JW, Kansagra AP
Clin Neurol Neurosurg. 2017 Sep; 16083-87. doi: 10.1016/j.clineuro.2017.06.014.

PMID:
    28692909
    [PubMed - indexed for MEDLINE]
Related citations


Arteriovenous malformations: epidemiology, clinical presentation, and diagnostic evaluation.
Osbun JW, Reynolds MR, Barrow DL
Handb Clin Neurol. 2017; 14325-29. doi: 10.1016/B978-0-444-63640-9.00003-5.

PMID:
    28552148
    [PubMed - indexed for MEDLINE]
Related citations


Classification and pathophysiology of spinal vascular malformations.
Abecassis IJ, Osbun JW, Kim L
Handb Clin Neurol. 2017; 143135-143. doi: 10.1016/B978-0-444-63640-9.00013-8.

PMID:
    28552135
    [PubMed - indexed for MEDLINE]
Related citations


Reduced Efficacy of the Pipeline Embolization Device in the Treatment of Posterior Communicating Region Aneurysms with Fetal Posterior Cerebral Artery Configuration.
Roy AK, Howard BM, Haussen DC, Osbun JW, Halani SH, Skukalek SL, Tong F, Nogueira RG, Dion JE, Cawley CM, Grossberg JA
Neurosurgery. 2018 May 1; 82(5)695-700. doi: 10.1093/neuros/nyx293.

PMID:
    28541503
    [PubMed - indexed for MEDLINE]
Related citations


Carotid cavernous fistula after Pipeline placement: a single-center experience and review of the literature.
Roy AK, Grossberg JA, Osbun JW, Skukalek SL, Howard BM, Ahmad FU, Tong F, Dion JE, Cawley CM
J Neurointerv Surg. 2017 Feb; 9(2)152-158. doi: 10.1136/neurintsurg-2016-012586.

PMID:
    27596802
    [PubMed - indexed for MEDLINE]
Related citations


Self-injection of household cleaning detergents into a ventriculoperitoneal shunt reservoir during a suicide attempt: a case report and literature review.
Signorelli JW, Osbun JW, Arias EJ, Reynolds LC, Chyatte D, Reynolds MR
Acta Neurochir (Wien). 2016 Sep; 158(9)1655-60. doi: 10.1007/s00701-016-2888-z.

PMID:
    27395018
    [PubMed - indexed for MEDLINE]
Related citations

In the News

In the News

Joshua Osbun, MD

Videos

Videos

Areas of Research Interest

Clinical outcome measures in the surgical, endovascular and medical treatment of cerebrovascular disease, and new device development and evaluation for use in interventional neuroangiography techniques