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Joseph P. Gaut, MD, PhD

Assistant Professor, Pathology & Immunology

Specialty Areas

Pathology - Anatomic
Surgical Pathology
Nephropathology

Board Certifications

Pathology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Medical kidney disease

  • Education
  • Publication & Research

Education

Education

Medical Degree: Washington University School of Medicine, St. Louis, MO 2004
AB, Chemistry: Washington University, St. Louis, MO 1996
Residency, Anatomic Pathology: Massachusetts General Hospital, Boston, MA 2009
Residency, Anatomic & Clinical Pathology: Barnes Jewish Hospital, St. Louis, MO 2011
Fellowship, Surgical Pathology: Washington University School of Medicine, St. Louis, MO 2012

Publication & Research

Publication & Research

The utility of surveillance biopsies in pediatric kidney transplantation.
Dharnidharka VR, Vyas N, Gaut JP, Walther L, Hmiel SP
Pediatr Nephrol. 2017 Dec 19; doi: 10.1007/s00467-017-3864-4.

PMID:
    29260318
    [PubMed - as supplied by publisher]
Related citations


Glomerular Diseases in Children.
Wenderfer SE, Gaut JP
Adv Chronic Kidney Dis. 2017 Nov; 24(6)364-371. doi: 10.1053/j.ackd.2017.09.005.

PMID:
    29229167
    [PubMed - in process]
Related citations


Evans Syndrome Complicated by Intratubular Hemoglobin Cast Nephropathy.
González I, Rais R, Gaut JP, Dehner LP
Case Rep Pediatr. 2017; 20175184587. doi: 10.1155/2017/5184587.

PMID:
    29163997
    [PubMed]
Related citations


Quantification of vascular damage in acute kidney injury with fluorine magnetic resonance imaging and spectroscopy.
Moore JK, Chen J, Pan H, Gaut JP, Jain S, Wickline SA
Magn Reson Med. 2017 Nov 16; doi: 10.1002/mrm.26985.

PMID:
    29148253
    [PubMed - as supplied by publisher]
Related citations


Anti-CD47 monoclonal antibody therapy reduces ischemia-reperfusion injury of renal allografts in a porcine model of donation after cardiac death.
Xu M, Wang X, Banan B, Chirumbole DL, Garcia-Aroz S, Balakrishnan A, Nayak DK, Zhang Z, Jia J, Upadhya GA, Gaut JP, Hiebsch R, Manning PT, Wu N, Lin Y, Chapman WC
Am J Transplant. 2017 Oct 31; doi: 10.1111/ajt.14567.

PMID:
    29087049
    [PubMed - as supplied by publisher]
Related citations


Accelerated humoral renal allograft rejection due to HLA-C14 mediated allosensitization to HLA-Bw6.
Persaud SP, Duffy B, Phelan DL, Mohanakumar T, Delos Santos R, Gaut JP, Liu C
Hum Immunol. 2017 Nov; 78(11-12)692-698. doi: 10.1016/j.humimm.2017.09.004.

PMID:
    29024716
    [PubMed - in process]
Related citations


CD47 blockade reduces ischemia/reperfusion injury in donation after cardiac death rat kidney transplantation.
Wang X, Xu M, Jia J, Zhang Z, Gaut JP, Upadhya GA, Manning PT, Lin Y, Chapman WC
Am J Transplant. 2017 Oct 4; doi: 10.1111/ajt.14523.

PMID:
    28975767
    [PubMed - as supplied by publisher]
Related citations


The activin receptor is stimulated in the skeleton, vasculature, heart, and kidney during chronic kidney disease.
Williams MJ, Sugatani T, Agapova OA, Fang Y, Gaut JP, Faugere MC, Malluche HH, Hruska KA
Kidney Int. 2018 Jan; 93(1)147-158. doi: 10.1016/j.kint.2017.06.016.

PMID:
    28843411
    [PubMed - in process]
Related citations


Routine use of clinical exome-based next-generation sequencing for evaluation of patients with thrombotic microangiopathies.
Gaut JP, Jain S, Pfeifer JD, Vigh-Conrad KA, Corliss M, Sharma MK, Heusel JW, Cottrell CE
Mod Pathol. 2017 Dec; 30(12)1739-1747. doi: 10.1038/modpathol.2017.90.

PMID:
    28752844
    [PubMed - in process]
Related citations


Case 5: Autoantibodies and an Elevated Creatinine in a 14-year-old Girl.
Charron A, Hesemann L, Gaut JP, Davis TK
Pediatr Rev. 2017 Jul; 38(7)337. doi: 10.1542/pir.2016-0192.

PMID:
    28667239
    [PubMed - in process]
Related citations


Development of immune response to tissue-restricted self-antigens in simultaneous kidney-pancreas transplant recipients with acute rejection.
Gunasekaran M, Vachharajani N, Gaut JP, Maw TT, Delos Santos R, Shenoy S, Chapman WC, Wellen J, Mohanakumar T
Clin Transplant. 2017 Aug; 31(8)doi: 10.1111/ctr.13009.

PMID:
    28639386
    [PubMed - in process]
Related citations


Smooth-Muscle Myopathy in Systemic Lupus Erythematosus Presenting With Intestinal Pseudo-Obstruction.
Yang C, Chen S, Gaut JP, Dehner LP
Am J Gastroenterol. 2016 Oct; 111(10)1501-1502. doi: 10.1038/ajg.2016.328.

PMID:
    27694873
    [PubMed - indexed for MEDLINE]
Related citations


Banff Histopathological Consensus Criteria for Preimplantation Kidney Biopsies.
Liapis H, Gaut JP, Klein C, Bagnasco S, Kraus E, Farris AB 3rd, Honsova E, Perkowska-Ptasinska A, David D, Goldberg J, Smith M, Mengel M, Haas M, Seshan S, Pegas KL, Horwedel T, Paliwa Y, Gao X, Landsittel D, Randhawa P, Banff Working Group.
Am J Transplant. 2017 Jan; 17(1)140-150. doi: 10.1111/ajt.13929.

PMID:
    27333454
    [PubMed - indexed for MEDLINE]
Related citations


ABO incompatible renal transplants and decreased likelihood for developing immune responses to HLA and kidney self-antigens.
Subramanian V, Gunasekaran M, Gaut JP, Phelan D, Vachharajani N, Santos RD, Wellen J, Shenoy S, Mohanakumar T
Hum Immunol. 2016 Jan; 77(1)76-83. doi: 10.1016/j.humimm.2015.10.014.

PMID:
    26476207
    [PubMed - indexed for MEDLINE]
Related citations


The Case | Diarrhea, weight loss, electrolyte abnormalities, and renal failure.
Kohler GD, Gaut JP, Morrison AR
Kidney Int. 2015 Aug; 88(2)421-2. doi: 10.1038/ki.2014.344.

PMID:
    26230210
    [PubMed - indexed for MEDLINE]
Related citations


Antithrombin nanoparticles improve kidney reperfusion and protect kidney function after ischemia-reperfusion injury.
Chen J, Vemuri C, Palekar RU, Gaut JP, Goette M, Hu L, Cui G, Zhang H, Wickline SA
Am J Physiol Renal Physiol. 2015 Apr 1; 308(7)F765-73. doi: 10.1152/ajprenal.00457.2014.

PMID:
    25651565
    [PubMed - indexed for MEDLINE]
Related citations


Nephrectomy for Non-neoplastic Kidney Diseases.
Gaut JP
Surg Pathol Clin. 2014 Sep; 7(3)307-19. doi: 10.1016/j.path.2014.04.010.

PMID:
    26837442
    [PubMed]
Related citations


CD47 blockade reduces ischemia-reperfusion injury and improves outcomes in a rat kidney transplant model.
Lin Y, Manning PT, Jia J, Gaut JP, Xiao Z, Capoccia BJ, Chen CC, Hiebsch RR, Upadhya G, Mohanakumar T, Frazier WA, Chapman WC
Transplantation. 2014 Aug 27; 98(4)394-401. doi: 10.1097/TP.0000000000000252.

PMID:
    24983310
    [PubMed - indexed for MEDLINE]
Related citations


Claudin 1 and nephrin label cellular crescents in diabetic glomerulosclerosis.
Gaut JP, Hoshi M, Jain S, Liapis H
Hum Pathol. 2014 Mar; 45(3)628-35. doi: 10.1016/j.humpath.2013.10.030.

PMID:
    24529330
    [PubMed - indexed for MEDLINE]
Related citations


Development of an immunoassay for the kidney-specific protein myo-inositol oxygenase, a potential biomarker of acute kidney injury.
Gaut JP, Crimmins DL, Ohlendorf MF, Lockwood CM, Griest TA, Brada NA, Hoshi M, Sato B, Hotchkiss RS, Jain S, Ladenson JH
Clin Chem. 2014 May; 60(5)747-57. doi: 10.1373/clinchem.2013.212993.

PMID:
    24486646
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Research focuses on acute kidney injury and the development of novel biomarkers to specifically and sensitively detect kidney injury in critically ill human patients. Other research interests include the pathophysiology of acute kidney injury and various types of glomerular disease.