Patient Portal

Jonathan J. Miner, MD, PhD

Assistant Professor, Medicine
Division of Rheumatology

Specialty Areas

Internal Medicine
Rheumatology
Autoimmune Disease

Board Certifications

Internal Medicine
Rheumatology

Hospital Affiliations

Barnes-Jewish Hospital

Languages

Russian

Referral Information

Not Accepting New Patients

Areas of Clinical Interest

Vasculitis

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Medicine Multispecialty Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 5
Office Phone: 314-286-2635
Fax: 314-286-2338

Education

Education

Fellowship, Rheumatology: Washington University School of Medicine, St. Louis, MO 2015
Residency, Internal Medicine: Barnes-Jewish Hospital, St. Louis, MO 2012
Medical Degree: University of Oklahoma College of Medicine, Oklahoma City, OK 2010
PhD, Biochemistry and Molecular Biology: University of Oklahoma College of Medicine, Oklahoma, OK 2010
BA/BS, Russian and Zoology: Brigham Young University, Provo, UT 2002

Publication & Research

Publication & Research

Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling.
Hansen AL, Buchan GJ, Rühl M, Mukai K, Salvatore SR, Ogawa E, Andersen SD, Iversen MB, Thielke AL, Gunderstofte C, Motwani M, Møller CT, Jakobsen AS, Fitzgerald KA, Roos J, Lin R, Maier TJ, Goldbach-Mansky R, Miner CA, Qian W, Miner JJ, Rigby RE, Rehwinkel J, Jakobsen MR, Arai H, Taguchi T, Schopfer FJ, Olagnier D, Holm CK
Proc Natl Acad Sci U S A. 2018 Aug 14; 115(33)E7768-E7775. doi: 10.1073/pnas.1806239115.

PMID:
    30061387
    [PubMed - in process]
Related citations


Zika virus-related neurotropic flaviviruses infect human placental explants and cause fetal demise in mice.
Platt DJ, Smith AM, Arora N, Diamond MS, Coyne CB, Miner JJ
Sci Transl Med. 2018 Jan 31; 10(426)pii: eaao7090. doi: 10.1126/scitranslmed.aao7090.

PMID:
    29386359
    [PubMed - in process]
Related citations


Editorial: Lessons Learned From Chikungunya in the Americas.
Miner JJ, Lenschow DJ
Arthritis Rheumatol. 2018 Apr; 70(4)477-479. doi: 10.1002/art.40421.

PMID:
    29361204
    [PubMed - in process]
Related citations


Consequences of congenital Zika virus infection.
Platt DJ, Miner JJ
Curr Opin Virol. 2017 Dec; 271-7. doi: 10.1016/j.coviro.2017.09.005.

PMID:
    29080429
    [PubMed - in process]
Related citations


STING-associated vasculopathy develops independently of IRF3 in mice.
Warner JD, Irizarry-Caro RA, Bennion BG, Ai TL, Smith AM, Miner CA, Sakai T, Gonugunta VK, Wu J, Platt DJ, Yan N, Miner JJ
J Exp Med. 2017 Nov 6; 214(11)3279-3292. doi: 10.1084/jem.20171351.

PMID:
    28951494
    [PubMed - indexed for MEDLINE]
Related citations


Gestational Stage and IFN-λ Signaling Regulate ZIKV Infection In Utero.
Jagger BW, Miner JJ, Cao B, Arora N, Smith AM, Kovacs A, Mysorekar IU, Coyne CB, Diamond MS
Cell Host Microbe. 2017 Sep 13; 22(3)366-376.e3. doi: 10.1016/j.chom.2017.08.012.

PMID:
    28910635
    [PubMed - indexed for MEDLINE]
Related citations


Congenital Zika virus infection: More than just microcephaly.
Miner JJ
Sci Transl Med. 2017 Jun 7; 9(393)pii: eaan8195. doi: 10.1126/scitranslmed.aan8195.

PMID:
    28592568
    [PubMed - in process]
Related citations


Dengue Antibodies, then Zika: A Fatal Sequence in Mice.
Miner JJ, Diamond MS
Immunity. 2017 May 16; 46(5)771-773. doi: 10.1016/j.immuni.2017.04.023.

PMID:
    28514683
    [PubMed - indexed for MEDLINE]
Related citations


Defeating Zika.
Miner JJ
Sci Transl Med. 2017 Apr 26; 9(387)pii: eaan2785. doi: 10.1126/scitranslmed.aan2785.

PMID:
    28446685
    [PubMed - indexed for MEDLINE]
Related citations


Gamete fusion gone viral.
Miner JJ
Sci Transl Med. 2017 Mar 15; 9(381)pii: eaam9866. doi: 10.1126/scitranslmed.aam9866.

PMID:
    28298425
    [PubMed - in process]
Related citations


Zika Virus Pathogenesis and Tissue Tropism.
Miner JJ, Diamond MS
Cell Host Microbe. 2017 Feb 8; 21(2)134-142. doi: 10.1016/j.chom.2017.01.004.

PMID:
    28182948
    [PubMed - indexed for MEDLINE]
Related citations


Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen.
Burt FJ, Chen W, Miner JJ, Lenschow DJ, Merits A, Schnettler E, Kohl A, Rudd PA, Taylor A, Herrero LJ, Zaid A, Ng LFP, Mahalingam S
Lancet Infect Dis. 2017 Apr; 17(4)e107-e117. doi: 10.1016/S1473-3099(16)30385-1.

PMID:
    28159534
    [PubMed - indexed for MEDLINE]
Related citations


Therapy with CTLA4-Ig and an antiviral monoclonal antibody controls chikungunya virus arthritis.
Miner JJ, Cook LE, Hong JP, Smith AM, Richner JM, Shimak RM, Young AR, Monte K, Poddar S, Crowe JE Jr, Lenschow DJ, Diamond MS
Sci Transl Med. 2017 Feb 1; 9(375)pii: eaah3438. doi: 10.1126/scitranslmed.aah3438.

PMID:
    28148840
    [PubMed - indexed for MEDLINE]
Related citations


Zika Virus Infection in Mice Causes Panuveitis with Shedding of Virus in Tears.
Miner JJ, Sene A, Richner JM, Smith AM, Santeford A, Ban N, Weger-Lucarelli J, Manzella F, Rückert C, Govero J, Noguchi KK, Ebel GD, Diamond MS, Apte RS
Cell Rep. 2016 Sep 20; 16(12)3208-3218. doi: 10.1016/j.celrep.2016.08.079.

PMID:
    27612415
    [PubMed - indexed for MEDLINE]
Related citations


A CRISPR screen defines a signal peptide processing pathway required by flaviviruses.
Zhang R, Miner JJ, Gorman MJ, Rausch K, Ramage H, White JP, Zuiani A, Zhang P, Fernandez E, Zhang Q, Dowd KA, Pierson TC, Cherry S, Diamond MS
Nature. 2016 Jul 7; 535(7610)164-8.

PMID:
    27383988
    [PubMed - indexed for MEDLINE]
Related citations


AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity.
Schmid ET, Pang IK, Carrera Silva EA, Bosurgi L, Miner JJ, Diamond MS, Iwasaki A, Rothlin CV
Elife. 2016 Jun 28; 5pii: e12414. doi: 10.7554/eLife.12414.

PMID:
    27350258
    [PubMed - indexed for MEDLINE]
Related citations


Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise.
Miner JJ, Cao B, Govero J, Smith AM, Fernandez E, Cabrera OH, Garber C, Noll M, Klein RS, Noguchi KK, Mysorekar IU, Diamond MS
Cell. 2016 May 19; 165(5)1081-1091. doi: 10.1016/j.cell.2016.05.008.

PMID:
    27180225
    [PubMed - indexed for MEDLINE]
Related citations


Understanding How Zika Virus Enters and Infects Neural Target Cells.
Miner JJ, Diamond MS
Cell Stem Cell. 2016 May 5; 18(5)559-60. doi: 10.1016/j.stem.2016.04.009.

PMID:
    27152436
    [PubMed - indexed for MEDLINE]
Related citations


A Mouse Model of Zika Virus Pathogenesis.
Lazear HM, Govero J, Smith AM, Platt DJ, Fernandez E, Miner JJ, Diamond MS
Cell Host Microbe. 2016 May 11; 19(5)720-30. doi: 10.1016/j.chom.2016.03.010.

PMID:
    27066744
    [PubMed - indexed for MEDLINE]
Related citations


Mechanisms of restriction of viral neuroinvasion at the blood-brain barrier.
Miner JJ, Diamond MS
Curr Opin Immunol. 2016 Feb; 3818-23. doi: 10.1016/j.coi.2015.10.008.

PMID:
    26590675
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Innate immunity, vasculitis and viral pathogenesis