Patient Portal

John S. Daniels, MD

Associate Professor, Clinical Medicine
Washington University Clinical Associates
University Internal Medicine and Diabetes Associates

Specialty Areas

Endocrinology
Diabetes
Internal Medicine
Primary Care

Board Certifications

Internal Medicine
Endocrinology and Metabolism

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Endocrinology, diabetes, metabolism

  • Location(s)
  • Education
  • Publication & Research

Location(s)

Location(s)

Center for Advanced Medicine
University Internal Medicine and Diabetes Associates

4921 Parkview Place
St. Louis, MO 63110

Suite: A
Floor: 13
Office Phone: 314-333-4100
Fax: 314-333-4115

Education

Education

Fellowship: Endocrinology and Metabolism, Washington University School of Medicine, St. Louis, Missouri 1979
Residency: Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 1977
Medical Degree: University of Arkansas School of Medicine, Little Rock, Arkansas 1974
B.A.: Washington University, St. Louis, Missouri 1970

Publication & Research

Publication & Research

Supratherapeutic Psychotropic Drug Levels in the Emergency Department and Their Association with Delirium Duration: A Preliminary Study.
Han JH, Chen A, Vasilevskis EE, Schnelle JF, Ely EW, Chandrasekhar R, Morrison RD, Ryan TP, Daniels JS, Sutherland JJ, Simmons SF
J Am Geriatr Soc. 2019 Sep 10; doi: 10.1111/jgs.16156.

PMID:
    31503339
    [PubMed - as supplied by publisher]
Related citations


The effect of the EP3 antagonist DG-041 on male mice with diet-induced obesity.
Ceddia RP, Downey JD, Morrison RD, Kraemer MP, Davis SE, Wu J, Lindsley CW, Yin H, Daniels JS, Breyer RM
Prostaglandins Other Lipid Mediat. 2019 Oct; 144106353. doi: 10.1016/j.prostaglandins.2019.106353.

PMID:
    31276827
    [PubMed - in process]
Related citations


Multi-immersion open-top light-sheet microscope for high-throughput imaging of cleared tissues.
Glaser AK, Reder NP, Chen Y, Yin C, Wei L, Kang S, Barner LA, Xie W, McCarty EF, Mao C, Halpern AR, Stoltzfus CR, Daniels JS, Gerner MY, Nicovich PR, Vaughan JC, True LD, Liu JTC
Nat Commun. 2019 Jul 4; 10(1)2781. doi: 10.1038/s41467-019-10534-0.

PMID:
    31273194
    [PubMed - indexed for MEDLINE]
Related citations


SAR inspired by aldehyde oxidase (AO) metabolism: Discovery of novel, CNS penetrant tricyclic M<sub>4</sub> PAMs.
Chopko TC, Han C, Gregro AR, Engers DW, Felts AS, Poslusney MS, Bollinger KA, Morrison RD, Bubser M, Lamsal A, Luscombe VB, Cho HP, Schnetz-Boutaud NC, Rodriguez AL, Chang S, Daniels JS, Stec DF, Niswender CM, Jones CK, Wood MR, Wood MW, Duggan ME, Brandon NJ, Conn PJ, Bridges TM, Lindsley CW, Melancon BJ
Bioorg Med Chem Lett. 2019 Aug 15; 29(16)2224-2228. doi: 10.1016/j.bmcl.2019.06.032.

PMID:
    31248774
    [PubMed - in process]
Related citations


VU0810464, a non-urea G protein-gated inwardly rectifying K<sup>+</sup> (K<sub>ir</sub> 3/GIRK) channel activator, exhibits enhanced selectivity for neuronal K<sub>ir</sub> 3 channels and reduces stress-induced hyperthermia in mice.
Vo BN, Abney KK, Anderson A, Marron Fernandez de Velasco E, Benneyworth MA, Daniels JS, Morrison RD, Hopkins CR, Weaver CD, Wickman K
Br J Pharmacol. 2019 Jul; 176(13)2238-2249. doi: 10.1111/bph.14671.

PMID:
    30924523
    [PubMed - in process]
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Correction to Analgesic Effects of the GIRK Activator, VU0466551, Alone and in Combination with Morphine in Acute and Persistent Pain Models.
Abney KK, Bubser M, Du Y, Kozek KA, Bridges TM, Lindsley CW, Daniels JS, Morrison RD, Wickman K, Hopkins CR, Jones CK, Weaver CD
ACS Chem Neurosci. 2019 May 15; 10(5)2621. doi: 10.1021/acschemneuro.9b00165.

PMID:
    30912639
    [PubMed]
Related citations


Assessment of Patient Medication Adherence, Medical Record Accuracy, and Medication Blood Concentrations for Prescription and Over-the-Counter Medications.
Sutherland JJ, Morrison RD, McNaughton CD, Daly TM, Milne SB, Daniels JS, Ryan TP
JAMA Netw Open. 2018 Nov 2; 1(7)e184196. doi: 10.1001/jamanetworkopen.2018.4196.

PMID:
    30646345
    [PubMed - indexed for MEDLINE]
Related citations


First-in-human study assessing safety, tolerability, and pharmacokinetics of 2-hydroxybenzylamine acetate, a selective dicarbonyl electrophile scavenger, in healthy volunteers.
Pitchford LM, Rathmacher JA, Fuller JC Jr, Daniels JS, Morrison RD, Akers WS, Abumrad NN, Amarnath V, Currey PM, Roberts LJ, Oates JA, Boutaud O
BMC Pharmacol Toxicol. 2019 Jan 5; 20(1)1. doi: 10.1186/s40360-018-0281-7.

PMID:
    30611293
    [PubMed - indexed for MEDLINE]
Related citations


Analgesic Effects of the GIRK Activator, VU0466551, Alone and in Combination with Morphine in Acute and Persistent Pain Models.
Abney KK, Bubser M, Du Y, Kozek KA, Bridges TM, Linsdley CW, Daniels JS, Morrison RD, Wickman K, Hopkins CR, Jones CK, Weaver CD
ACS Chem Neurosci. 2019 Mar 20; 10(3)1294-1299. doi: 10.1021/acschemneuro.8b00370.

PMID:
    30474955
    [PubMed - in process]
Related citations


In vitro safety pharmacology evaluation of 2-hydroxybenzylamine acetate.
Fuller JC Jr, Pitchford LM, Morrison RD, Daniels JS, Flynn CR, Abumrad NN, Oates JA, Boutaud O, Rathmacher JA
Food Chem Toxicol. 2018 Nov; 121541-548. doi: 10.1016/j.fct.2018.09.047.

PMID:
    30253245
    [PubMed - indexed for MEDLINE]
Related citations


Scalable Nanogap Sensors for Non-Redox Enzyme Assays.
Su X, Tayebi N, Credo GM, Wu K, Elibol OH, Liu DJ, Daniels JS, Li H, Hall DA, Varma M
ACS Sens. 2018 Sep 28; 3(9)1773-1781. doi: 10.1021/acssensors.8b00500.

PMID:
    30156096
    [PubMed - indexed for MEDLINE]
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Discovery of 6-(pyrimidin-5-ylmethyl)quinoline-8-carboxamide negative allosteric modulators of metabotropic glutamate receptor subtype 5.
Felts AS, Rodriguez AL, Morrison RD, Blobaum AL, Byers FW, Daniels JS, Niswender CM, Conn PJ, Lindsley CW, Emmitte KA
Bioorg Med Chem Lett. 2018 Jun 1; 28(10)1679-1685. doi: 10.1016/j.bmcl.2018.04.053.

PMID:
    29705142
    [PubMed - indexed for MEDLINE]
Related citations


Medication Exposure in Highly Adherent Psychiatry Patients.
Sutherland JJ, Daly TM, Jacobs K, Khawam EA, Pozuelo L, Morrison RD, Milne SB, Daniels JS, Ryan TP
ACS Chem Neurosci. 2018 Mar 21; 9(3)555-562. doi: 10.1021/acschemneuro.7b00375.

PMID:
    29155555
    [PubMed - indexed for MEDLINE]
Related citations


Discovery of imidazo[1,2-a]-, [1,2,4]triazolo[4,3-a]-, and [1,2,4]triazolo[1,5-a]pyridine-8-carboxamide negative allosteric modulators of metabotropic glutamate receptor subtype 5.
Felts AS, Rodriguez AL, Morrison RD, Bollinger KA, Venable DF, Blobaum AL, Byers FW, Thompson Gray A, Daniels JS, Niswender CM, Jones CK, Conn PJ, Lindsley CW, Emmitte KA
Bioorg Med Chem Lett. 2017 Nov 1; 27(21)4858-4866. doi: 10.1016/j.bmcl.2017.09.042.

PMID:
    28958625
    [PubMed - indexed for MEDLINE]
Related citations


Medication adherence, medical record accuracy, and medication exposure in real-world patients using comprehensive medication monitoring.
Ryan TP, Morrison RD, Sutherland JJ, Milne SB, Ryan KA, Daniels JS, Misra-Hebert A, Hicks JK, Vogan E, Teng K, Daly TM
PLoS One. 2017; 12(9)e0185471. doi: 10.1371/journal.pone.0185471.

PMID:
    28957369
    [PubMed - indexed for MEDLINE]
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mGlu<sub>7</sub> potentiation rescues cognitive, social, and respiratory phenotypes in a mouse model of Rett syndrome.
Gogliotti RG, Senter RK, Fisher NM, Adams J, Zamorano R, Walker AG, Blobaum AL, Engers DW, Hopkins CR, Daniels JS, Jones CK, Lindsley CW, Xiang Z, Conn PJ, Niswender CM
Sci Transl Med. 2017 Aug 16; 9(403)pii: eaai7459. doi: 10.1126/scitranslmed.aai7459.

PMID:
    28814546
    [PubMed - indexed for MEDLINE]
Related citations


Discovery and Characterization of 1H-Pyrazol-5-yl-2-phenylacetamides as Novel, Non-Urea-Containing GIRK1/2 Potassium Channel Activators.
Wieting JM, Vadukoot AK, Sharma S, Abney KK, Bridges TM, Daniels JS, Morrison RD, Wickman K, Weaver CD, Hopkins CR
ACS Chem Neurosci. 2017 Sep 20; 8(9)1873-1879. doi: 10.1021/acschemneuro.7b00217.

PMID:
    28697302
    [PubMed - indexed for MEDLINE]
Related citations


Managing Psychotropic Medications in Complex, Real-World Patients Using Comprehensive Therapeutic Drug Monitoring.
Sutherland JJ, Morrison RD, Daniels JS, Milne SB, Ryan TP
ACS Chem Neurosci. 2017 Aug 16; 8(8)1641-1644. doi: 10.1021/acschemneuro.7b00209.

PMID:
    28640591
    [PubMed - indexed for MEDLINE]
Related citations


Discovery of N-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide (VU0424238): A Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Selected for Clinical Evaluation.
Felts AS, Rodriguez AL, Blobaum AL, Morrison RD, Bates BS, Thompson Gray A, Rook JM, Tantawy MN, Byers FW, Chang S, Venable DF, Luscombe VB, Tamagnan GD, Niswender CM, Daniels JS, Jones CK, Conn PJ, Lindsley CW, Emmitte KA
J Med Chem. 2017 Jun 22; 60(12)5072-5085. doi: 10.1021/acs.jmedchem.7b00410.

PMID:
    28530802
    [PubMed - indexed for MEDLINE]
Related citations


Visualizing Calcium Flux in Freely Moving Nematode Embryos.
Ardiel EL, Kumar A, Marbach J, Christensen R, Gupta R, Duncan W, Daniels JS, Stuurman N, Colón-Ramos D, Shroff H
Biophys J. 2017 May 9; 112(9)1975-1983. doi: 10.1016/j.bpj.2017.02.035.

PMID:
    28494967
    [PubMed - indexed for MEDLINE]
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