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John P. Lynch, MD

Professor, Medicine
Chief Medical Officer
Vice-President, Barnes-Jewish Hospital

Specialty Areas

Lung Transplantation
Pulmonary Fibrosis

Board Certifications

Internal Medicine
Pulmonary Disease
Critical Care

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Lung transplantation, pulmonary disease, pulmonary hypertension, pulmonary fibrosis

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Barnes-Jewish Hospital

1 Barnes-Jewish Hospital Plaza
St. Louis, MO 63110

Office Phone: 314-362-2130

Education

Education

Fellowship: Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, Missouri
Residency: Internal Medicine, Barnes Hospital, St. Louis, Missouri 1991
Medical Degree: Georgetown University, Washington, District of Columbia 1989
B.A.: St. Louis University, St. Louis, Missouri 1983

Publication & Research

Publication & Research

Rightsizing Root Phenotypes for Drought resistance.
Lynch JP
J Exp Bot. 2018 Feb 17; doi: 10.1093/jxb/ery048.

PMID:
    29471525
    [PubMed - as supplied by publisher]
Related citations


Buffered delivery of phosphate to Arabidopsis alters responses to low phosphate.
Hanlon MT, Ray S, Saengwilai P, Luthe D, Lynch JP, Brown KM
J Exp Bot. 2018 Jan 3; doi: 10.1093/jxb/erx454.

PMID:
    29304231
    [PubMed - as supplied by publisher]
Related citations


Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion.
Lynch JP, Werder RB, Loh Z, Sikder MAA, Curren B, Zhang V, Rogers MJ, Lane K, Simpson J, Mazzone SB, Spann K, Hayball J, Diener K, Everard ML, Blyth CC, Forstner C, Dennis PG, Murtaza N, Morrison M, Ó Cuív P, Zhang P, Haque A, Hill GR, Sly PD, Upham JW, Phipps S
J Exp Med. 2018 Feb 5; 215(2)537-557. doi: 10.1084/jem.20170298.

PMID:
    29273643
    [PubMed - in process]
Related citations


GUCY2C maintains intestinal LGR5<sup>+</sup> stem cells by opposing ER stress.
Kraft CL, Rappaport JA, Snook AE, Pattison AM, Lynch JP, Waldman SA
Oncotarget. 2017 Nov 28; 8(61)102923-102933. doi: 10.18632/oncotarget.22084.

PMID:
    29262534
    [PubMed]
Related citations


Gene Expression Profiling of Bronchoalveolar Lavage Cells during Aspergillus Colonization of the Lung Allograft.
Weigt SS, Wang X, Palchevskiy V, Patel N, Derhovanessian A, Shino MY, Sayah DM, Lynch JP 3rd, Saggar R, Ross DJ, Kubak BM, Ardehali A, Palmer S, Husain S, Belperio JA
Transplantation. 2017 Dec 18; doi: 10.1097/TP.0000000000002058.

PMID:
    29256975
    [PubMed - as supplied by publisher]
Related citations


Imipenem-Relebactam and Meropenem-Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations.
Zhanel GG, Lawrence CK, Adam H, Schweizer F, Zelenitsky S, Zhanel M, Lagacé-Wiens PRS, Walkty A, Denisuik A, Golden A, Gin AS, Hoban DJ, Lynch JP 3rd, Karlowsky JA
Drugs. 2018 Jan; 78(1)65-98. doi: 10.1007/s40265-017-0851-9.

PMID:
    29230684
    [PubMed - in process]
Related citations


Critical Role of Plasmacytoid Dendritic Cells in Regulating Gene Expression and Innate Immune Responses to Human Rhinovirus-16.
Xi Y, Troy NM, Anderson D, Pena OM, Lynch JP, Phipps S, Bosco A, Upham JW
Front Immunol. 2017; 81351. doi: 10.3389/fimmu.2017.01351.

PMID:
    29118754
    [PubMed]
Related citations


Reduction in Root Secondary Growth as a Strategy for Phosphorus Acquisition.
Strock CF, Morrow de la Riva L, Lynch JP
Plant Physiol. 2018 Jan; 176(1)691-703. doi: 10.1104/pp.17.01583.

PMID:
    29118249
    [PubMed - in process]
Related citations


Pulmonary Hypertension Complicating Connective Tissue Disease.
Volkmann ER, Chung A, Saggar R, Belperio JA, Lynch JP 3rd
Semin Respir Crit Care Med. 2017 Oct; 38(5)619-635. doi: 10.1055/s-0037-1606203.

PMID:
    29032565
    [PubMed - in process]
Related citations


Chronic IL-33 expression predisposes to virus-induced asthma exacerbations by increasing type 2 inflammation and dampening antiviral immunity.
Werder RB, Zhang V, Lynch JP, Snape N, Upham JW, Spann K, Phipps S
J Allergy Clin Immunol. 2017 Sep 22; pii: S0091-6749(17)31500-2. doi: 10.1016/j.jaci.2017.07.051.

PMID:
    28947081
    [PubMed - as supplied by publisher]
Related citations


Gene Expression Profiling of Bronchoalveolar Lavage Cells Preceding a Clinical Diagnosis of Chronic Lung Allograft Dysfunction.
Weigt SS, Wang X, Palchevskiy V, Patel N, Derhovanessian A, Shino MY, Sayah DM, Gregson AL, Lynch JP 3rd, Saggar R, Ross DJ, Ardehali A, Elashoff D, Belperio JA
Ann Am Thorac Soc. 2017 Sep; 14(Supplement_3)S252. doi: 10.1513/AnnalsATS.201608-618MG.

PMID:
    28945470
    [PubMed - in process]
Related citations


Shaping 3D Root System Architecture.
Morris EC, Griffiths M, Golebiowska A, Mairhofer S, Burr-Hersey J, Goh T, von Wangenheim D, Atkinson B, Sturrock CJ, Lynch JP, Vissenberg K, Ritz K, Wells DM, Mooney SJ, Bennett MJ
Curr Biol. 2017 Sep 11; 27(17)R919-R930. doi: 10.1016/j.cub.2017.06.043.

PMID:
    28898665
    [PubMed - in process]
Related citations


Cardiac Involvement in Sarcoidosis: Evolving Concepts in Diagnosis and Treatment.
Sayah DM, Bradfield JS, Moriarty JM, Belperio JA, Lynch JP 3rd
Semin Respir Crit Care Med. 2017 Aug; 38(4)477-498. doi: 10.1055/s-0037-1602381.

PMID:
    28750462
    [PubMed - in process]
Related citations


Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity.
Yan KS, Gevaert O, Zheng GXY, Anchang B, Probert CS, Larkin KA, Davies PS, Cheng ZF, Kaddis JS, Han A, Roelf K, Calderon RI, Cynn E, Hu X, Mandleywala K, Wilhelmy J, Grimes SM, Corney DC, Boutet SC, Terry JM, Belgrader P, Ziraldo SB, Mikkelsen TS, Wang F, von Furstenberg RJ, Smith NR, Chandrakesan P, May R, Chrissy MAS, Jain R, Cartwright CA, Niland JC, Hong YK, Carrington J, Breault DT, Epstein J, Houchen CW, Lynch JP, Martin MG, Plevritis SK, Curtis C, Ji HP, Li L, Henning SJ, Wong MH, Kuo CJ
Cell Stem Cell. 2017 Jul 6; 21(1)78-90.e6. doi: 10.1016/j.stem.2017.06.014.

PMID:
    28686870
    [PubMed - in process]
Related citations


The prognostic importance of CXCR3 chemokine during organizing pneumonia on the risk of chronic lung allograft dysfunction after lung transplantation.
Shino MY, Weigt SS, Li N, Palchevskiy V, Derhovanessian A, Saggar R, Sayah DM, Huynh RH, Gregson AL, Fishbein MC, Ardehali A, Ross DJ, Lynch JP 3rd, Elashoff RM, Belperio JA
PLoS One. 2017; 12(7)e0180281. doi: 10.1371/journal.pone.0180281.

PMID:
    28686641
    [PubMed - indexed for MEDLINE]
Related citations


Root Cortical Senescence Improves Growth under Suboptimal Availability of N, P, and K.
Schneider HM, Postma JA, Wojciechowski T, Kuppe C, Lynch JP
Plant Physiol. 2017 Aug; 174(4)2333-2347. doi: 10.1104/pp.17.00648.

PMID:
    28667049
    [PubMed - indexed for MEDLINE]
Related citations


Morphological Plant Modeling: Unleashing Geometric and Topological Potential within the Plant Sciences.
Bucksch A, Atta-Boateng A, Azihou AF, Battogtokh D, Baumgartner A, Binder BM, Braybrook SA, Chang C, Coneva V, DeWitt TJ, Fletcher AG, Gehan MA, Diaz-Martinez DH, Hong L, Iyer-Pascuzzi AS, Klein LL, Leiboff S, Li M, Lynch JP, Maizel A, Maloof JN, Markelz RJC, Martinez CC, Miller LA, Mio W, Palubicki W, Poorter H, Pradal C, Price CA, Puttonen E, Reese JB, Rellán-Álvarez R, Spalding EP, Sparks EE, Topp CN, Williams JH, Chitwood DH
Front Plant Sci. 2017; 8900. doi: 10.3389/fpls.2017.00900.

PMID:
    28659934
    [PubMed]
Related citations


OpenSimRoot: widening the scope and application of root architectural models.
Postma JA, Kuppe C, Owen MR, Mellor N, Griffiths M, Bennett MJ, Lynch JP, Watt M
New Phytol. 2017 Aug; 215(3)1274-1286. doi: 10.1111/nph.14641.

PMID:
    28653341
    [PubMed - in process]
Related citations


Modeling Esophagitis Using Human Three-Dimensional Organotypic Culture System.
Laczkó D, Wang F, Johnson FB, Jhala N, Rosztóczy A, Ginsberg GG, Falk GW, Rustgi AK, Lynch JP
Am J Pathol. 2017 Aug; 187(8)1787-1799. doi: 10.1016/j.ajpath.2017.04.013.

PMID:
    28627413
    [PubMed - indexed for MEDLINE]
Related citations


Emergence of Antimicrobial Resistance among Pseudomonas aeruginosa: Implications for Therapy.
Lynch JP 3rd, Zhanel GG, Clark NM
Semin Respir Crit Care Med. 2017 Jun; 38(3)326-345. doi: 10.1055/s-0037-1602583.

PMID:
    28578556
    [PubMed - in process]
Related citations