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John P. Lynch, MD

Professor, Medicine
Chief Medical Officer
Vice-President, Barnes-Jewish Hospital

Specialty Areas

Lung Transplantation
Pulmonary Fibrosis

Board Certifications

Internal Medicine
Pulmonary Disease
Critical Care

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Lung transplantation, pulmonary disease, pulmonary hypertension, pulmonary fibrosis

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Barnes-Jewish Hospital

1 Barnes-Jewish Hospital Plaza
St. Louis, MO 63110

Office Phone: 314-362-2130

Education

Education

Fellowship: Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, Missouri
Residency: Internal Medicine, Barnes Hospital, St. Louis, Missouri 1991
Medical Degree: Georgetown University, Washington, District of Columbia 1989
B.A.: St. Louis University, St. Louis, Missouri 1983

Publication & Research

Publication & Research

Correction to: Imipenem-Relebactam and Meropenem-Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations.
Zhanel GG, Lawrence CK, Adam H, Schweizer F, Zelenitsky S, Zhanel M, Lagacé-Wiens PRS, Walkty A, Denisuik A, Golden A, Gin AS, Hoban DJ, Lynch JP 3rd, Karlowsky JA
Drugs. 2018 May 10; doi: 10.1007/s40265-018-0910-x.

PMID:
    29748749
    [PubMed - as supplied by publisher]
Related citations


PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-<b>λ</b> production.
Werder RB, Lynch JP, Simpson JC, Zhang V, Hodge NH, Poh M, Forbes-Blom E, Kulis C, Smythe ML, Upham JW, Spann K, Everard ML, Phipps S
Sci Transl Med. 2018 May 9; 10(440)pii: eaao0052. doi: 10.1126/scitranslmed.aao0052.

PMID:
    29743346
    [PubMed - in process]
Related citations


Author Correction: A mechanistic framework for auxin dependent Arabidopsis root hair elongation to low external phosphate.
Bhosale R, Giri J, Pandey BK, Giehl RFH, Hartmann A, Traini R, Truskina J, Leftley N, Hanlon M, Swarup K, Rashed A, Voß U, Alonso J, Stepanova A, Yun J, Ljung K, Brown KM, Lynch JP, Dolan L, Vernoux T, Bishopp A, Wells D, von Wirén N, Bennett MJ, Swarup R
Nat Commun. 2018 May 2; 9(1)1818. doi: 10.1038/s41467-018-04281-x.

PMID:
    29720582
    [PubMed - in process]
Related citations


A mechanistic framework for auxin dependent Arabidopsis root hair elongation to low external phosphate.
Bhosale R, Giri J, Pandey BK, Giehl RFH, Hartmann A, Traini R, Truskina J, Leftley N, Hanlon M, Swarup K, Rashed A, Voß U, Alonso J, Stepanova A, Yun J, Ljung K, Brown KM, Lynch JP, Dolan L, Vernoux T, Bishopp A, Wells D, von Wirén N, Bennett MJ, Swarup R
Nat Commun. 2018 Apr 12; 9(1)1409. doi: 10.1038/s41467-018-03851-3.

PMID:
    29651114
    [PubMed - in process]
Related citations


Large Crown Root Number Improves Topsoil Foraging and Phosphorus Acquisition.
Sun B, Gao Y, Lynch JP
Plant Physiol. 2018 May; 177(1)90-104. doi: 10.1104/pp.18.00234.

PMID:
    29618638
    [PubMed - in process]
Related citations


Fungal Infections Complicating Lung Transplantation.
Clark NM, Weigt SS, Fishbein MC, Kubak B, Belperio JA, Lynch JP 3rd
Semin Respir Crit Care Med. 2018 Apr; 39(2)227-254. doi: 10.1055/s-0037-1617443.

PMID:
    29579774
    [PubMed - in process]
Related citations


Chronic Lung Allograft Dysfunction: Evolving Concepts and Therapies.
DerHovanessian A, Wallace WD, Lynch JP 3rd, Belperio JA, Weigt SS
Semin Respir Crit Care Med. 2018 Apr; 39(2)155-171. doi: 10.1055/s-0037-1618567.

PMID:
    29579768
    [PubMed - in process]
Related citations


Reduced root cortical burden improves growth and grain yield under low phosphorus availability in maize.
Galindo-Castañeda T, Brown KM, Lynch JP
Plant Cell Environ. 2018 Mar 25; doi: 10.1111/pce.13197.

PMID:
    29574982
    [PubMed - as supplied by publisher]
Related citations


Pulmonary Allograft Versus Host Disease.
Dai DW, Garber B, Weigt SS, Worswick S, Kubak BM, Lynch JP 3rd, Shino MY, DerHovanessian A, Saggar R, Ross DJ, Sayah DM
Transplant Direct. 2017 Dec; 3(12)e333. doi: 10.1097/TXD.0000000000000749.

PMID:
    29536034
    [PubMed]
Related citations


Rightsizing Root Phenotypes for Drought resistance.
Lynch JP
J Exp Bot. 2018 Feb 17; doi: 10.1093/jxb/ery048.

PMID:
    29471525
    [PubMed - as supplied by publisher]
Related citations


Buffered delivery of phosphate to Arabidopsis alters responses to low phosphate.
Hanlon MT, Ray S, Saengwilai P, Luthe D, Lynch JP, Brown KM
J Exp Bot. 2018 Jan 3; doi: 10.1093/jxb/erx454.

PMID:
    29304231
    [PubMed - as supplied by publisher]
Related citations


Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion.
Lynch JP, Werder RB, Loh Z, Sikder MAA, Curren B, Zhang V, Rogers MJ, Lane K, Simpson J, Mazzone SB, Spann K, Hayball J, Diener K, Everard ML, Blyth CC, Forstner C, Dennis PG, Murtaza N, Morrison M, Ó Cuív P, Zhang P, Haque A, Hill GR, Sly PD, Upham JW, Phipps S
J Exp Med. 2018 Feb 5; 215(2)537-557. doi: 10.1084/jem.20170298.

PMID:
    29273643
    [PubMed - in process]
Related citations


GUCY2C maintains intestinal LGR5<sup>+</sup> stem cells by opposing ER stress.
Kraft CL, Rappaport JA, Snook AE, Pattison AM, Lynch JP, Waldman SA
Oncotarget. 2017 Nov 28; 8(61)102923-102933. doi: 10.18632/oncotarget.22084.

PMID:
    29262534
    [PubMed]
Related citations


Gene Expression Profiling of Bronchoalveolar Lavage Cells During Aspergillus Colonization of the Lung Allograft.
Weigt SS, Wang X, Palchevskiy V, Patel N, Derhovanessian A, Shino MY, Sayah DM, Lynch JP 3rd, Saggar R, Ross DJ, Kubak BM, Ardehali A, Palmer S, Husain S, Belperio JA
Transplantation. 2018 Jun; 102(6)986-993. doi: 10.1097/TP.0000000000002058.

PMID:
    29256975
    [PubMed - in process]
Related citations


Imipenem-Relebactam and Meropenem-Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations.
Zhanel GG, Lawrence CK, Adam H, Schweizer F, Zelenitsky S, Zhanel M, Lagacé-Wiens PRS, Walkty A, Denisuik A, Golden A, Gin AS, Hoban DJ, Lynch JP 3rd, Karlowsky JA
Drugs. 2018 Jan; 78(1)65-98. doi: 10.1007/s40265-017-0851-9.

PMID:
    29230684
    [PubMed - in process]
Related citations


Critical Role of Plasmacytoid Dendritic Cells in Regulating Gene Expression and Innate Immune Responses to Human Rhinovirus-16.
Xi Y, Troy NM, Anderson D, Pena OM, Lynch JP, Phipps S, Bosco A, Upham JW
Front Immunol. 2017; 81351. doi: 10.3389/fimmu.2017.01351.

PMID:
    29118754
    [PubMed]
Related citations


Reduction in Root Secondary Growth as a Strategy for Phosphorus Acquisition.
Strock CF, Morrow de la Riva L, Lynch JP
Plant Physiol. 2018 Jan; 176(1)691-703. doi: 10.1104/pp.17.01583.

PMID:
    29118249
    [PubMed - in process]
Related citations


Pulmonary Hypertension Complicating Connective Tissue Disease.
Volkmann ER, Chung A, Saggar R, Belperio JA, Lynch JP 3rd
Semin Respir Crit Care Med. 2017 Oct; 38(5)619-635. doi: 10.1055/s-0037-1606203.

PMID:
    29032565
    [PubMed - in process]
Related citations


Chronic IL-33 expression predisposes to virus-induced asthma exacerbations by increasing type 2 inflammation and dampening antiviral immunity.
Werder RB, Zhang V, Lynch JP, Snape N, Upham JW, Spann K, Phipps S
J Allergy Clin Immunol. 2018 May; 141(5)1607-1619.e9. doi: 10.1016/j.jaci.2017.07.051.

PMID:
    28947081
    [PubMed - in process]
Related citations


Gene Expression Profiling of Bronchoalveolar Lavage Cells Preceding a Clinical Diagnosis of Chronic Lung Allograft Dysfunction.
Weigt SS, Wang X, Palchevskiy V, Patel N, Derhovanessian A, Shino MY, Sayah DM, Gregson AL, Lynch JP 3rd, Saggar R, Ross DJ, Ardehali A, Elashoff D, Belperio JA
Ann Am Thorac Soc. 2017 Sep; 14(Supplement_3)S252. doi: 10.1513/AnnalsATS.201608-618MG.

PMID:
    28945470
    [PubMed - in process]
Related citations