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John Nicholas Constantino, MD

Blanche F. Ittleson Professor of Psychiatry and Pediatrics
Director, William Greenleaf Elliot Division of Child & Adolescent Psychiatry

Specialty Areas

Child Psychiatry
Autism
Child and Adolescent Psychiatry

Board Certifications

Child and Adolescent Psychiatry

Hospital Affiliations

Barnes-Jewish Hospital
St. Louis Children's Hospital

Referral Information

Professional Consultation Only

Areas of Clinical Interest

Disorders of social development in children (infancy through early adulthood) including autism, abnormally aggressive behavior, personality disorder, and psychiatric complications of neurodevelopmental disorders.

  • Education
  • Publication & Research
  • Financial Disclosures

Education

Education

Research Fellow: Psychiatric Epidemiology, Washington University School of Medicine, St. Louis, Missouri 1996
Fellowship: Child Psychiatry, Albert Einstein College of Medicine, Bronx, New York 1993
Residency: Psychiatry, Albert Einstein College of Medicine, Bronx, New York 1992
Residency: Pediatrics, Albert Einstein College of Medicine, Bronx, New York 1990
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 1988
B.A.: Cornell University, Ithaca, New York 1984

Publication & Research

Publication & Research

Taking stock of critical clues to understanding sex differences in the prevalence and recurrence of autism.
Constantino JN
Autism. 2017 Jun 1; 1362361317704414. doi: 10.1177/1362361317704414.

PMID:
    28595452
    [PubMed - as supplied by publisher]
Related citations


Functional neuroimaging of high-risk 6-month-old infants predicts a diagnosis of autism at 24 months of age.
Emerson RW, Adams C, Nishino T, Hazlett HC, Wolff JJ, Zwaigenbaum L, Constantino JN, Shen MD, Swanson MR, Elison JT, Kandala S, Estes AM, Botteron KN, Collins L, Dager SR, Evans AC, Gerig G, Gu H, McKinstry RC, Paterson S, Schultz RT, Styner M, IBIS Network., Schlaggar BL, Pruett JR Jr, Piven J
Sci Transl Med. 2017 Jun 7; 9(393)pii: eaag2882. doi: 10.1126/scitranslmed.aag2882.

PMID:
    28592562
    [PubMed - in process]
Related citations


The Early Origins of Autism.
Constantino JN, Marrus N
Child Adolesc Psychiatr Clin N Am. 2017 Jul; 26(3)555-570. doi: 10.1016/j.chc.2017.02.008.

PMID:
    28577609
    [PubMed - in process]
Related citations


Measurement of Autism Symptomatology in Children With Neurodevelopmental Impairment.
Constantino JN
J Am Acad Child Adolesc Psychiatry. 2017 Apr; 56(4)354-355. doi: 10.1016/j.jaac.2017.01.017.

PMID:
    28335881
    [PubMed - in process]
Related citations


Early brain development in infants at high risk for autism spectrum disorder.
Hazlett HC, Gu H, Munsell BC, Kim SH, Styner M, Wolff JJ, Elison JT, Swanson MR, Zhu H, Botteron KN, Collins DL, Constantino JN, Dager SR, Estes AM, Evans AC, Fonov VS, Gerig G, Kostopoulos P, McKinstry RC, Pandey J, Paterson S, Pruett JR, Schultz RT, Shaw DW, Zwaigenbaum L, Piven J, IBIS Network., Clinical Sites., Data Coordinating Center., Image Processing Core., Statistical Analysis.
Nature. 2017 Feb 15; 542(7641)348-351. doi: 10.1038/nature21369.

PMID:
    28202961
    [PubMed - indexed for MEDLINE]
Related citations


Joint Attention and Brain Functional Connectivity in Infants and Toddlers.
Eggebrecht AT, Elison JT, Feczko E, Todorov A, Wolff JJ, Kandala S, Adams CM, Snyder AZ, Lewis JD, Estes AM, Zwaigenbaum L, Botteron KN, McKinstry RC, Constantino JN, Evans A, Hazlett HC, Dager S, Paterson SJ, Schultz RT, Styner MA, Gerig G, Das S, Kostopoulos P, IBIS Network†., Schlaggar BL, Petersen SE, Piven J, Pruett JR Jr
Cereb Cortex. 2017 Mar 1; 27(3)1709-1720. doi: 10.1093/cercor/bhw403.

PMID:
    28062515
    [PubMed - indexed for MEDLINE]
Related citations


Disease Burden and Symptom Structure of Autism in Neurofibromatosis Type 1: A Study of the International NF1-ASD Consortium Team (INFACT).
Morris SM, Acosta MT, Garg S, Green J, Huson S, Legius E, North KN, Payne JM, Plasschaert E, Frazier TW, Weiss LA, Zhang Y, Gutmann DH, Constantino JN
JAMA Psychiatry. 2016 Dec 1; 73(12)1276-1284. doi: 10.1001/jamapsychiatry.2016.2600.

PMID:
    27760236
    [PubMed - indexed for MEDLINE]
Related citations


Sensory Responsiveness in Siblings of Children with Autism Spectrum Disorders.
Hilton CL, Babb-Keeble A, Westover EE, Zhang Y, Adams C, Collins DM, Karmarkar A, Reistetter TA, Constantino JN
J Autism Dev Disord. 2016 Dec; 46(12)3778-3787.

PMID:
    27704293
    [PubMed - in process]
Related citations


Quantitative autistic trait measurements index background genetic risk for ASD in Hispanic families.
Page J, Constantino JN, Zambrana K, Martin E, Tunc I, Zhang Y, Abbacchi A, Messinger D
Mol Autism. 2016; 7(1)39. doi: 10.1186/s13229-016-0100-1.

PMID:
    27606047
    [PubMed - in process]
Related citations


The social responsiveness scale in relation to DSM IV and DSM5 ASD in Korean children.
Cheon KA, Park JI, Koh YJ, Song J, Hong HJ, Kim YK, Lim EC, Kwon H, Ha M, Lim MH, Paik KC, Constantino JN, Leventhal B, Kim YS
Autism Res. 2016 Sep; 9(9)970-80. doi: 10.1002/aur.1671.

PMID:
    27604989
    [PubMed - in process]
Related citations


Data from the Baby Siblings Research Consortium confirm and specify the nature of the female protective effect in autism: A commentary on Messinger et al.
Constantino JN
Mol Autism. 2016; 732. doi: 10.1186/s13229-016-0092-x.

PMID:
    27358720
    [PubMed]
Related citations


Complexities of X chromosome inactivation status in female human induced pluripotent stem cells-a brief review and scientific update for autism research.
Dandulakis MG, Meganathan K, Kroll KL, Bonni A, Constantino JN
J Neurodev Disord. 2016; 822. doi: 10.1186/s11689-016-9155-8.

PMID:
    27303449
    [PubMed]
Related citations


Two-Generation Psychiatric Intervention in the Prevention of Early Childhood Maltreatment Recidivism.
Constantino JN, Ben-David V, Navsaria N, Spiegel TE, Glowinski AL, Rogers CE, Jonson-Reid M
Am J Psychiatry. 2016 Jun 1; 173(6)566-73. doi: 10.1176/appi.ajp.2015.15070944.

PMID:
    27245189
    [PubMed - in process]
Related citations


Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years--Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2012.
Christensen DL, Baio J, Van Naarden Braun K, Bilder D, Charles J, Constantino JN, Daniels J, Durkin MS, Fitzgerald RT, Kurzius-Spencer M, Lee LC, Pettygrove S, Robinson C, Schulz E, Wells C, Wingate MS, Zahorodny W, Yeargin-Allsopp M, Centers for Disease Control and Prevention (CDC).
MMWR Surveill Summ. 2016 Apr 1; 65(3)1-23. doi: 10.15585/mmwr.ss6503a1.

PMID:
    27031587
    [PubMed - indexed for MEDLINE]
Related citations


Child Maltreatment Prevention and the Scope of Child and Adolescent Psychiatry.
Constantino JN
Child Adolesc Psychiatr Clin N Am. 2016 Apr; 25(2)157-65. doi: 10.1016/j.chc.2015.11.003.

PMID:
    26980121
    [PubMed - indexed for MEDLINE]
Related citations


Symptoms of autism spectrum disorder and anxiety: shared familial transmission and cross-assortative mating.
Duvekot J, van der Ende J, Constantino JN, Verhulst FC, Greaves-Lord K
J Child Psychol Psychiatry. 2016 Jun; 57(6)759-69. doi: 10.1111/jcpp.12508.

PMID:
    26714925
    [PubMed - in process]
Related citations


The Lag Structure of Intrinsic Activity is Focally Altered in High Functioning Adults with Autism.
Mitra A, Snyder AZ, Constantino JN, Raichle ME
Cereb Cortex. 2017 Feb 1; 27(2)1083-1093. doi: 10.1093/cercor/bhv294.

PMID:
    26656726
    [PubMed - in process]
Related citations


Quantitative autism symptom patterns recapitulate differential mechanisms of genetic transmission in single and multiple incidence families.
Frazier TW, Youngstrom EA, Hardan AY, Georgiades S, Constantino JN, Eng C
Mol Autism. 2015; 658. doi: 10.1186/s13229-015-0050-z.

PMID:
    26512313
    [PubMed]
Related citations


Diagnosis of autism spectrum disorder: reconciling the syndrome, its diverse origins, and variation in expression.
Constantino JN, Charman T
Lancet Neurol. 2016 Mar; 15(3)279-91. doi: 10.1016/S1474-4422(15)00151-9.

PMID:
    26497771
    [PubMed - indexed for MEDLINE]
Related citations


Sex and gender differences in autism spectrum disorder: summarizing evidence gaps and identifying emerging areas of priority.
Halladay AK, Bishop S, Constantino JN, Daniels AM, Koenig K, Palmer K, Messinger D, Pelphrey K, Sanders SJ, Singer AT, Taylor JL, Szatmari P
Mol Autism. 2015; 636. doi: 10.1186/s13229-015-0019-y.

PMID:
    26075049
    [PubMed]
Related citations

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following earned financial interests during calendar year 2016.

Company Name: Western Psychological

Royalties: $50,001 - $100,000

Equity: No

Consulting/Advisory Board:

Speaker Fees:

Reporting Date: May 01, 2017