Patient Portal

John Lawrence Frater Jr., MD

Assistant Professor, Pathology and Immunology

Specialty Areas

Hematopathology
Pathology

Board Certifications

Anatomical and Clinical Pathology
Hematology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Hematopathology, disorders of hemoglobin, automated hematology

  • Education
  • Publication & Research

Education

Education

BS, Chemistry: University of Notre Dame, Notre Dame, IN 1992
Medical Degree: Medical College of Ohio, Toledo, OH 1996
Residency, Anatomical and Clinical Pathology: Cleveland Clinic Foundation, Cleveland, OH 2001
Fellowship, Hematopathology: Northwestern University Medical School, Chicago, IL 2003

Publication & Research

Publication & Research

CD4-positive diffuse large B-cell lymphoma: A variant with aggressive clinical potential.
Hussaini MO, Kreisel FH, Hassan A, Nguyen TT, Frater JL
World J Methodol. 2016 Sep 26; 6(3)181-6. doi: 10.5662/wjm.v6.i3.181.

PMID:
    27679780
    [PubMed]
Related citations


Cutaneous mantle cell lymphoma: a clinicopathologic review of 10 cases.
Gru AA, Hurley MY, Salavaggione AL, Brodell L, Sheinbein D, Anadkat M, Porcu P, Frater JL
J Cutan Pathol. 2016 Dec; 43(12)1112-1120. doi: 10.1111/cup.12802.

PMID:
    27539965
    [PubMed - indexed for MEDLINE]
Related citations


The histiocytoses: as easy as ABC (or LCMRH).
Frater JL
Blood. 2016 Jun 2; 127(22)2655-6. doi: 10.1182/blood-2016-03-706267.

PMID:
    27257174
    [PubMed - indexed for MEDLINE]
Related citations


Congenital Acute Myeloid Leukemia with Unique Translocation t(11;19)(q23;p13.3).
Yarbrough CK, Bandt SK, Hurth K, Wambach JA, Rao R, Kulkarni S, White FV, Frater JL, Leonard JR
Cureus. 2015 Jul; 7(7)e289. doi: 10.7759/cureus.289.

PMID:
    26244121
    [PubMed]
Related citations


Expression of TIA1 and PAX5 in Classical Hodgkin Lymphoma at Initial Diagnosis May Predict Clinical Outcome.
Nguyen TT, Frater JL, Klein J, Chen L, Bartlett NL, Foyil KV, Kreisel FH
Appl Immunohistochem Mol Morphol. 2016 Jul; 24(6)383-91. doi: 10.1097/PAI.0000000000000200.

PMID:
    26067141
    [PubMed - indexed for MEDLINE]
Related citations


Is the band count useful in predicting the presence of septicemia in patients with hematologic malignancies?
Mehrad M, Hudson JB, Frater JL
Int J Lab Hematol. 2015 Oct; 37(5)e112-4. doi: 10.1111/ijlh.12339.

PMID:
    25801655
    [PubMed - indexed for MEDLINE]
Related citations


Clinical presentation, progression, and outcome of patients with clonal B-cell counts of less than 5 × 10(9)/l, 5 to 10 × 10(9)/l, and more than 10 × 10(9)/l and chronic lymphocytic leukemia immunophenotype.
Foster AE, Nguyen TT, Al-Hammadi N, Frater JL, Hassan A, Kreisel F
Am J Clin Pathol. 2015 Jan; 143(1)70-7. doi: 10.1309/AJCPIXUB5MZK8ECI.

PMID:
    25511144
    [PubMed - indexed for MEDLINE]
Related citations


T-cell prolymphocytic leukemia frequently shows cutaneous involvement and is associated with gains of MYC, loss of ATM, and TCL1A rearrangement.
Hsi AC, Robirds DH, Luo J, Kreisel FH, Frater JL, Nguyen TT
Am J Surg Pathol. 2014 Nov; 38(11)1468-83. doi: 10.1097/PAS.0000000000000272.

PMID:
    25310835
    [PubMed - indexed for MEDLINE]
Related citations


Mast cell leukemia with prolonged survival on PKC412/midostaurin.
Xu X, Kreisel FH, Frater JL, Hassan A
Int J Clin Exp Pathol. 2014; 7(6)3439-43.

PMID:
    25031773
    [PubMed - indexed for MEDLINE]
Related citations


A quality improvement assessment of multiple, concurrent flow cytometry analyses at a tertiary care center.
Karnes HE, Frater JL
Int J Lab Hematol. 2015 Feb; 37(1)90-7. doi: 10.1111/ijlh.12244.

PMID:
    24811935
    [PubMed - indexed for MEDLINE]
Related citations


CD163 immunohistochemistry is superior to CD68 in predicting outcome in classical Hodgkin lymphoma.
Klein JL, Nguyen TT, Bien-Willner GA, Chen L, Foyil KV, Bartlett NL, Duncavage EJ, Hassan A, Frater JL, Kreisel F
Am J Clin Pathol. 2014 Mar; 141(3)381-7. doi: 10.1309/AJCP61TLMXLSLJYS.

PMID:
    24515766
    [PubMed - indexed for MEDLINE]
Related citations


Clinicopathologic features of adult T-cell leukemias/lymphomas at a North American tertiary care medical center: infrequent involvement of the central nervous system.
Hsi AC, Kreisel FH, Frater JL, Nguyen TT
Am J Surg Pathol. 2014 Feb; 38(2)245-56. doi: 10.1097/PAS.0000000000000109.

PMID:
    24418858
    [PubMed - indexed for MEDLINE]
Related citations


Utility of flow cytometry of cerebrospinal fluid as a screening tool in the diagnosis of central nervous system lymphoma.
Pittman M, Treese S, Chen L, Frater JL, Nguyen TT, Hassan A, Kreisel F
Arch Pathol Lab Med. 2013 Nov; 137(11)1610-8. doi: 10.5858/arpa.2012-0313-OA.

PMID:
    24168498
    [PubMed - indexed for MEDLINE]
Related citations


Acute EBV infection masquerading as "In-situ Follicular Lymphoma": a pitfall in the differential diagnosis of this entity.
Gru AA, Kreisel F, Duncavage E, Nguyen TT, Hassan A, Frater JL
Diagn Pathol. 2013 Jun 19; 8100. doi: 10.1186/1746-1596-8-100.

PMID:
    23782909
    [PubMed - indexed for MEDLINE]
Related citations


Anaplastic large-cell lymphoma with aberrant expression of multiple cytokeratins masquerading as metastatic carcinoma of unknown primary.
Nguyen TT, Kreisel FH, Frater JL, Bartlett NL
J Clin Oncol. 2013 Nov 20; 31(33)e443-5. doi: 10.1200/JCO.2012.46.7910.

PMID:
    23775969
    [PubMed - indexed for MEDLINE]
Related citations


High prevalence of 1p36 microdeletions in B-cell non-Hodgkin lymphomas (NHL) is associated with PAX7 loss.
Gru AA, Hussaini M, Nguyen T, Frater JL, Kreisel F, Hassan A
Int J Lab Hematol. 2013 Aug; 35(4)e1-5. doi: 10.1111/ijlh.12034.

PMID:
    23205730
    [PubMed - indexed for MEDLINE]
Related citations


Cutaneous myeloid sarcoma: natural history and biology of an uncommon manifestation of acute myeloid leukemia.
Hurley MY, Ghahramani GK, Frisch S, Armbrecht ES, Lind AC, Nguyen TT, Hassan A, Kreisel FH, Frater JL
Acta Derm Venereol. 2013 May; 93(3)319-24. doi: 10.2340/00015555-1458.

PMID:
    23165700
    [PubMed - indexed for MEDLINE]
Related citations


Use of a United States-based laboratory as a hematopathology reference center for a developing country: logistics and results.
Deetz CO, Scott MG, Ladenson JH, Seyoum M, Hassan A, Kreisel FH, Nguyen TT, Frater JL
Int J Lab Hematol. 2013 Feb; 35(1)77-81. doi: 10.1111/ijlh.12001.

PMID:
    22938565
    [PubMed - indexed for MEDLINE]
Related citations


Cover quizlet: recurrent pustules on the scalp of an infant. Eosinophilic pustular folliculitis.
Ghahramani GK, Abraham NF, Burkemper NM, Frater JL, Hurley MY
J Cutan Pathol. 2012 Sep; 39(9)815-6. doi: 10.1111/j.1600-0560.2012.01986.x.

PMID:
    22905683
    [PubMed - indexed for MEDLINE]
Related citations


Gastrointestinal lymphomas in a North American population: clinicopathologic features from one major Central-Midwestern United States tertiary care medical center.
Warrick J, Luo J, Robirds D, Branson J, Frater JL, Kreisel F, Hassan A, Nguyen TT
Diagn Pathol. 2012 Jun 28; 776. doi: 10.1186/1746-1596-7-76.

PMID:
    22742986
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Cutaneous manifestations of hematologic malignancy and the use of new advances in automated hematology to aid patient care.