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Faculty Physicians

John F. DiPersio, MD, PhD

Virginia E. and Samuel J Golman Endowed Professorship of Medicine, Pathology & Immunology
Professor, Pediatrics
Professor, Pathology
Chief, Division of Oncology
Deputy Director, Siteman Cancer Center

Specialty Areas

Bone Marrow Transplant
Hematology
Leukemia
Hematologic Malignancies
Gene Therapy

Board Certifications

Hematology
Internal Medicine
Oncology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Hematology, oncology, bone marrow transplantation, hematopoietic stem cell transplantation, molecular biology, cellular biology, leukemia, MDS, aplastic anemia

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Siteman Cancer Center

4921 Parkview Place
St. Louis, MO 63110
Phone: 314-747-7222

Suite: B
Floor: 7
Office Phone: 314-454-8304
Fax: 314-454-7551

Education

Education

Fellowship: Hematology & Oncology, UCLA School of Medicine, Los Angeles, CA 1987
Chief Resident: Internal Medicine, Parkland Memorial Hospital, Dallas, TX 1984
Residency: Internal Medicine, Parkland Memorial Hospital, Dallas, TX 1983
Ph.D.: Microbiology, University of Rochester School of Medicine, Rochester, NY 1980
Medical Degree: University Of Rochester School of Medicine, Rochester, NY 1980
B.A.: Biology, Williams College 1973

Publication & Research

Publication & Research

Targeting the leukemia-stroma interaction in acute myeloid leukemia: rationale and latest evidence.
Rashidi A, DiPersio JF
Ther Adv Hematol. 2016 Feb; 7(1)40-51. doi: 10.1177/2040620715619307.

PMID:
    26834953
    [PubMed]
Related citations


Ex vivo and in vivo evaluation of over-expressed VLA-4 in multiple myeloma using LLP2A imaging agents.
Soodgupta D, Zhou H, Beaino W, Lu L, Snee M, Skeath J, DiPersio JF, Akers WJ, Laforest R, Anderson CJ, Tomasson MH, Shokeen M
J Nucl Med. 2016 Jan 7; pii: jnumed.115.164624.

PMID:
    26742713
    [PubMed - as supplied by publisher]
Related citations


Patterns and functional implications of rare germline variants across 12 cancer types.
Lu C, Xie M, Wendl MC, Wang J, McLellan MD, Leiserson MD, Huang KL, Wyczalkowski MA, Jayasinghe R, Banerjee T, Ning J, Tripathi P, Zhang Q, Niu B, Ye K, Schmidt HK, Fulton RS, McMichael JF, Batra P, Kandoth C, Bharadwaj M, Koboldt DC, Miller CA, Kanchi KL, Eldred JM, Larson DE, Welch JS, You M, Ozenberger BA, Govindan R, Walter MJ, Ellis MJ, Mardis ER, Graubert TA, Dipersio JF, Ley TJ, Wilson RK, Goodfellow PJ, Raphael BJ, Chen F, Johnson KJ, Parvin JD, Ding L
Nat Commun. 2015 Dec 22; 610086. doi: 10.1038/ncomms10086.

PMID:
    26689913
    [PubMed - in process]
Related citations


A phase I study of carfilzomib for relapsed or refractory acute myeloid and acute lymphoblastic leukemia.
Wartman LD, Fiala MA, Fletcher T, Hawkins ER, Cashen A, DiPersio JF, Jacoby MA, Stockerl-Goldstein KE, Pusic I, Uy GL, Westervelt P, Vij R
Leuk Lymphoma. 2015 Oct 5; 1-3.

PMID:
    26674111
    [PubMed - as supplied by publisher]
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Phase-1/-2 study of pomalidomide in chronic GvHD.
Pusic I, Rettig MP, DiPersio JF, Bauer S, McFarland K, Gale RP, Pavletic SZ
Bone Marrow Transplant. 2015 Dec 14; doi: 10.1038/bmt.2015.298.

PMID:
    26657832
    [PubMed - as supplied by publisher]
Related citations


Rapid expansion of pre-existing non-leukemic hematopoietic clones frequently follows induction therapy for de novo AML.
Wong TN, Miller CA, Klco JM, Petti A, Demeter R, Helton NM, Li T, Fulton RS, Heath SE, Mardis ER, Westervelt P, DiPersio JF, Walter MJ, Welch JS, Graubert TA, Wilson RK, Ley TJ, Link DC
Blood. 2015 Dec 2; pii: blood-2015-10-677021.

PMID:
    26631115
    [PubMed - as supplied by publisher]
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NCCN Oncology Research Program's Investigator Steering Committee and NCCN Best Practices Committee Molecular Profiling Surveys.
Kurzrock R, Colevas AD, Olszanski A, Akerley W, Arteaga CL, Carson WE 3rd, Clark JW, DiPersio JF, Ettinger DS, Morgan RJ Jr, Schwartzberg LS, Venook AP, Gocke CD, Tait J, Stewart FM
J Natl Compr Canc Netw. 2015 Nov; 13(11)1337-46.

PMID:
    26553764
    [PubMed - in process]
Related citations


Acute myeloid leukemia presenting with extensive bone marrow necrosis, leukemia cutis and testicular involvement: successful treatment with allogeneic hematopoietic stem cell transplantation.
Rashidi A, DiPersio JF, Westervelt P, Abboud CN, Romee R
Bone Marrow Transplant. 2015 Nov 9; doi: 10.1038/bmt.2015.272.

PMID:
    26551781
    [PubMed - as supplied by publisher]
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Targeting CD123 in acute myeloid leukemia using a T-cell-directed dual-affinity retargeting platform.
Al-Hussaini M, Rettig MP, Ritchey JK, Karpova D, Uy GL, Eissenberg LG, Gao F, Eades WC, Bonvini E, Chichili GR, Moore PA, Johnson S, Collins L, DiPersio JF
Blood. 2016 Jan 7; 127(1)122-31. doi: 10.1182/blood-2014-05-575704.

PMID:
    26531164
    [PubMed - in process]
Related citations


Outcomes of Allogeneic Stem Cell Transplantation in Elderly Patients with Acute Myeloid Leukemia: A Systematic Review and Meta-analysis.
Rashidi A, Ebadi M, Colditz GA, DiPersio JF
Biol Blood Marrow Transplant. 2015 Oct 31; pii: S1083-8791(15)00708-9. doi: 10.1016/j.bbmt.2015.10.019.

PMID:
    26529178
    [PubMed - as supplied by publisher]
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The effect of donor characteristics on survival after unrelated donor transplantation for hematologic malignancy.
Kollman C, Spellman SR, Zhang MJ, Hassebroek A, Anasetti C, Antin JH, Champlin RE, Confer DL, DiPersio JF, Fernandez-Viña M, Hartzman RJ, Horowitz MM, Hurley CK, Karanes C, Maiers M, Mueller CR, Perales MA, Setterholm M, Woolfrey AE, Yu N, Eapen M
Blood. 2016 Jan 14; 127(2)260-7. doi: 10.1182/blood-2015-08-663823.

PMID:
    26527675
    [PubMed - in process]
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Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia.
Churpek JE, Pyrtel K, Kanchi KL, Shao J, Koboldt D, Miller CA, Shen D, Fulton R, O'Laughlin M, Fronick C, Pusic I, Uy GL, Braunstein EM, Levis M, Ross J, Elliott K, Heath S, Jiang A, Westervelt P, DiPersio JF, Link DC, Walter MJ, Welch J, Wilson R, Ley TJ, Godley LA, Graubert TA
Blood. 2015 Nov 26; 126(22)2484-90. doi: 10.1182/blood-2015-04-641100.

PMID:
    26492932
    [PubMed - in process]
Related citations


Targeting bone marrow lymphoid niches in acute lymphoblastic leukemia.
Uy GL, Hsu YM, Schmidt AP, Stock W, Fletcher TR, Trinkaus KM, Westervelt P, DiPersio JF, Link DC
Leuk Res. 2015 Dec; 39(12)1437-42. doi: 10.1016/j.leukres.2015.09.020.

PMID:
    26467815
    [PubMed - in process]
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Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia.
Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Helton NM, Duncavage EJ, Payton JE, Baty J, Heath SE, Griffith OL, Shen D, Hundal J, Chang GS, Fulton R, O'Laughlin M, Fronick C, Magrini V, Demeter RT, Larson DE, Kulkarni S, Ozenberger BA, Welch JS, Walter MJ, Graubert TA, Westervelt P, Radich JP, Link DC, Mardis ER, DiPersio JF, Wilson RK, Ley TJ
JAMA. 2015 Aug 25; 314(8)811-22. doi: 10.1001/jama.2015.9643.

PMID:
    26305651
    [PubMed - indexed for MEDLINE]
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GPR18 Controls Reconstitution of Mouse Small Intestine Intraepithelial Lymphocytes following Bone Marrow Transplantation.
Becker AM, Callahan DJ, Richner JM, Choi J, DiPersio JF, Diamond MS, Bhattacharya D
PLoS One. 2015; 10(7)e0133854. doi: 10.1371/journal.pone.0133854.

PMID:
    26197390
    [PubMed - in process]
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A pooled analysis of overall survival in COMFORT-I and COMFORT-II, 2 randomized phase III trials of ruxolitinib for the treatment of myelofibrosis.
Vannucchi AM, Kantarjian HM, Kiladjian JJ, Gotlib J, Cervantes F, Mesa RA, Sarlis NJ, Peng W, Sandor V, Gopalakrishna P, Hmissi A, Stalbovskaya V, Gupta V, Harrison C, Verstovsek S, COMFORT Investigators
Haematologica. 2015 Sep; 100(9)1139-45. doi: 10.3324/haematol.2014.119545.

PMID:
    26069290
    [PubMed - in process]
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Maintenance Therapy with Decitabine after Allogeneic Stem Cell Transplantation for Acute Myelogenous Leukemia and Myelodysplastic Syndrome.
Pusic I, Choi J, Fiala MA, Gao F, Holt M, Cashen AF, Vij R, Abboud CN, Stockerl-Goldstein KE, Jacoby MA, Uy GL, Westervelt P, DiPersio JF
Biol Blood Marrow Transplant. 2015 Oct; 21(10)1761-9. doi: 10.1016/j.bbmt.2015.05.026.

PMID:
    26055299
    [PubMed - in process]
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Oral Debio1143 (AT406), an antagonist of inhibitor of apoptosis proteins, combined with daunorubicin and cytarabine in patients with poor-risk acute myeloid leukemia--results of a phase I dose-escalation study.
DiPersio JF, Erba HP, Larson RA, Luger SM, Tallman MS, Brill JM, Vuagniaux G, Rouits E, Sorensen JM, Zanna C
Clin Lymphoma Myeloma Leuk. 2015 Jul; 15(7)443-9. doi: 10.1016/j.clml.2015.02.020.

PMID:
    25842225
    [PubMed - in process]
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Hematologic Recovery after Pretransplant Chemotherapy Does Not Influence Survival after Allogeneic Hematopoietic Cell Transplantation in Acute Myeloid Leukemia Patients.
Vu K, Manjappa S, DiPersio JF, Gao F, Westervelt P, Vij R, Stockerl-Goldstein KE, Uy GL, Abboud CN, Schroeder MA, Fehniger TA, Cashen AF, Romee R
Biol Blood Marrow Transplant. 2015 Aug; 21(8)1425-30. doi: 10.1016/j.bbmt.2015.03.022.

PMID:
    25840336
    [PubMed - in process]
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[(18)F]FHBG PET/CT Imaging of CD34-TK75 Transduced Donor T Cells in Relapsed Allogeneic Stem Cell Transplant Patients: Safety and Feasibility.
Eissenberg LG, Rettig MP, Ritchey JK, Prior JL, Schwarz SW, Frye J, White BS, Fulton RS, Ghobadi A, Cooper ML, Couriel DR, Seegulam ME, Piwnica-Worms D, Dehdashti F, Cornetta K, DiPersio JF
Mol Ther. 2015 Jun; 23(6)1110-22. doi: 10.1038/mt.2015.48.

PMID:
    25807290
    [PubMed - in process]
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