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John F. DiPersio, MD, PhD

Virginia E. and Samuel J Golman Endowed Professorship of Medicine, Pathology & Immunology
Professor, Pediatrics
Professor, Pathology
Chief, Division of Oncology
Deputy Director, Siteman Cancer Center

Specialty Areas

Bone Marrow Transplant
Hematology
Leukemia
Hematologic Malignancies
Gene Therapy

Board Certifications

Hematology
Internal Medicine
Oncology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Hematology, oncology, bone marrow transplantation, hematopoietic stem cell transplantation, molecular biology, cellular biology, leukemia, MDS, aplastic anemia

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Siteman Cancer Center

4921 Parkview Place
St. Louis, MO 63110
Phone: 314-747-7222

Suite: B
Floor: 7
Office Phone: 314-454-8304
Fax: 314-454-7551

Education

Education

Fellowship: Hematology & Oncology, UCLA School of Medicine, Los Angeles, CA 1987
Chief Resident: Internal Medicine, Parkland Memorial Hospital, Dallas, TX 1984
Residency: Internal Medicine, Parkland Memorial Hospital, Dallas, TX 1983
Ph.D.: Microbiology, University of Rochester School of Medicine, Rochester, NY 1980
Medical Degree: University Of Rochester School of Medicine, Rochester, NY 1980
B.A.: Biology, Williams College 1973

Publication & Research

Publication & Research

CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression.
Spencer DH, Russler-Germain DA, Ketkar S, Helton NM, Lamprecht TL, Fulton RS, Fronick CC, O'Laughlin M, Heath SE, Shinawi M, Westervelt P, Payton JE, Wartman LD, Welch JS, Wilson RK, Walter MJ, Link DC, DiPersio JF, Ley TJ
Cell. 2017 Feb 13; pii: S0092-8674(17)30106-X. doi: 10.1016/j.cell.2017.01.021.

PMID:
    28215704
    [PubMed - as supplied by publisher]
Related citations


Anti-leukemia efficacy and mechanisms of action of SL-101, a novel anti-CD123 antibody-conjugate, in acute myeloid leukemia.
Han L, Jorgensen JL, Brooks C, Shi C, Zhang Q, Nogueras González GM, Cavazos A, Pan R, Mu H, Wang S, Zhou J, Alatrash G, Ciurea SO, Rettig M, DiPersio JF, Cortes JE, Huang X, Kantarjian H, Andreeff M, Ravandi-Kashani F, Konopleva M
Clin Cancer Res. 2017 Jan 17; pii: clincanres.1904.2016. doi: 10.1158/1078-0432.CCR-16-1904.

PMID:
    28096272
    [PubMed - as supplied by publisher]
Related citations


T Cell-Replete Peripheral Blood Haploidentical Hematopoietic Cell Transplantation with Post-Transplantation Cyclophosphamide Results in Outcomes Similar to Transplantation from Traditionally Matched Donors in Active Disease Acute Myeloid Leukemia.
How J, Slade M, Vu K, DiPersio JF, Westervelt P, Uy GL, Abboud CN, Vij R, Schroeder MA, Fehniger TA, Romee R
Biol Blood Marrow Transplant. 2017 Jan 10; pii: S1083-8791(17)30193-3. doi: 10.1016/j.bbmt.2017.01.068.

PMID:
    28087457
    [PubMed - as supplied by publisher]
Related citations


Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy.
Duncavage EJ, Uy GL, Petti AA, Miller CA, Lee YS, Tandon B, Gao F, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Jacoby MA, Cashen AF, Wartman LD, Walter MJ, Westervelt P, Link DC, DiPersio JF, Ley TJ, Welch JS
Blood. 2017 Jan 12; pii: blood-2016-10-745273. doi: 10.1182/blood-2016-10-745273.

PMID:
    28082444
    [PubMed - as supplied by publisher]
Related citations


Single institution experience with G-CSF mobilized T-cell replete haploidentical hematopoietic cell transplantation.
Huselton E, Slade M, DiPersio JF, Westervelt P, Vij R, Uy GL, Fehniger TA, Abboud CN, Gao F, Schroeder MA, Romee R
Bone Marrow Transplant. 2017 Jan 9; doi: 10.1038/bmt.2016.354.

PMID:
    28067881
    [PubMed - as supplied by publisher]
Related citations


Epidemiology of infections following haploidentical peripheral blood hematopoietic cell transplantation.
Slade M, Goldsmith S, Romee R, DiPersio JF, Dubberke ER, Westervelt P, Uy GL, Lawrence SJ
Transpl Infect Dis. 2017 Feb; 19(1)doi: 10.1111/tid.12629.

PMID:
    28030755
    [PubMed - in process]
Related citations


TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes.
Welch JS, Petti AA, Miller CA, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Baty JD, Duncavage EJ, Tandon B, Lee YS, Wartman LD, Uy GL, Ghobadi A, Tomasson MH, Pusic I, Romee R, Fehniger TA, Stockerl-Goldstein KE, Vij R, Oh ST, Abboud CN, Cashen AF, Schroeder MA, Jacoby MA, Heath SE, Luber K, Janke MR, Hantel A, Khan N, Sukhanova MJ, Knoebel RW, Stock W, Graubert TA, Walter MJ, Westervelt P, Link DC, DiPersio JF, Ley TJ
N Engl J Med. 2016 Nov 24; 375(21)2023-2036.

PMID:
    27959731
    [PubMed - indexed for MEDLINE]
Related citations


A proposed biology- and biomarker-based algorithm for management of acute GvHD.
Ali AM, DiPersio JF, Schroeder MA
Bone Marrow Transplant. 2017 Feb; 52(2)337-340. doi: 10.1038/bmt.2016.289.

PMID:
    27869807
    [PubMed - in process]
Related citations


Tissue polymerase chain reaction for the diagnosis of cytomegalovirus disease after allogeneic hematopoietic cell transplantation.
Rashidi A, Vij KR, Buller RS, Wylie KM, Storch GA, DiPersio JF
Am J Hematol. 2017 Feb; 92(2)E19-E20. doi: 10.1002/ajh.24609.

PMID:
    27859620
    [PubMed - in process]
Related citations


Cytomegalovirus viremia, disease, and impact on relapse in T-cell replete peripheral blood haploidentical hematopoietic cell transplantation with post-transplant cyclophosphamide.
Goldsmith SR, Slade M, DiPersio JF, Westervelt P, Lawrence SJ, Uy GL, Abboud CN, Vij R, Schroeder MA, Fehniger TA, Dubberke ER, Trinkaus K, Romee R
Haematologica. 2016 Nov; 101(11)e465-e468.

PMID:
    27443287
    [PubMed - in process]
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Dynamic changes in the clonal structure of MDS and AML in response to epigenetic therapy.
Uy GL, Duncavage EJ, Chang GS, Jacoby MA, Miller CA, Shao J, Heath S, Elliott K, Reineck T, Fulton RS, Fronick CC, O'Laughlin M, Ganel L, Abboud CN, Cashen AF, DiPersio JF, Wilson RK, Link DC, Welch JS, Ley TJ, Graubert TA, Westervelt P, Walter MJ
Leukemia. 2016 Nov 18; doi: 10.1038/leu.2016.282.

PMID:
    27740633
    [PubMed - as supplied by publisher]
Related citations


Enhanced in utero allogeneic engraftment in mice after mobilizing fetal HSCs by α4β1/7 inhibition.
Kim AG, Vrecenak JD, Boelig MM, Eissenberg L, Rettig MP, Riley JS, Holt MS, Conner MA, Loukogeorgakis SP, Li H, DiPersio JF, Flake AW, Peranteau WH
Blood. 2016 Nov 17; 128(20)2457-2461.

PMID:
    27650329
    [PubMed - in process]
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Acute lymphoblastic leukemia presenting with hypereosinophilia: Case report and review of the literature.
Ali AM, Rashidi A, DiPersio JF
Blood Cells Mol Dis. 2016 Aug 31; pii: S1079-9796(16)30135-8. doi: 10.1016/j.bcmd.2016.08.004.

PMID:
    27634176
    [PubMed - as supplied by publisher]
Related citations


Post-transplant high-dose cyclophosphamide after HLA-matched vs haploidentical hematopoietic cell transplantation for AML.
Rashidi A, Slade M, DiPersio JF, Westervelt P, Vij R, Romee R
Bone Marrow Transplant. 2016 Dec; 51(12)1561-1564. doi: 10.1038/bmt.2016.217.

PMID:
    27526282
    [PubMed - in process]
Related citations


Maintenance therapy in acute myeloid leukemia: an evidence-based review of randomized trials.
Rashidi A, Walter RB, Tallman MS, Appelbaum FR, DiPersio JF
Blood. 2016 Aug 11; 128(6)763-73. doi: 10.1182/blood-2016-03-674127.

PMID:
    27354720
    [PubMed - in process]
Related citations


Divergent viral presentation among human tumors and adjacent normal tissues.
Cao S, Wendl MC, Wyczalkowski MA, Wylie K, Ye K, Jayasinghe R, Xie M, Wu S, Niu B, Grubb R 3rd, Johnson KJ, Gay H, Chen K, Rader JS, Dipersio JF, Chen F, Ding L
Sci Rep. 2016 Jun 24; 628294. doi: 10.1038/srep28294.

PMID:
    27339696
    [PubMed - in process]
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Severe Cytokine-Release Syndrome after T Cell-Replete Peripheral Blood Haploidentical Donor Transplantation Is Associated with Poor Survival and Anti-IL-6 Therapy Is Safe and Well Tolerated.
Abboud R, Keller J, Slade M, DiPersio JF, Westervelt P, Rettig MP, Meier S, Fehniger TA, Abboud CN, Uy GL, Vij R, Trinkaus KM, Schroeder MA, Romee R
Biol Blood Marrow Transplant. 2016 Oct; 22(10)1851-60. doi: 10.1016/j.bbmt.2016.06.010.

PMID:
    27318038
    [PubMed - in process]
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Remobilization of hematopoietic stem cells in healthy donors for allogeneic transplantation.
Fiala MA, Park S, Slade M, DiPersio JF, Stockerl-Goldstein KE
Transfusion. 2016 Sep; 56(9)2331-5. doi: 10.1111/trf.13688.

PMID:
    27311884
    [PubMed - in process]
Related citations


Quality of Life: A Tiebreaker in CEBPA Double-Mutated Acute Myeloid Leukemia.
Rashidi A, DiPersio JF
Biol Blood Marrow Transplant. 2016 Aug; 22(8)1535-6. doi: 10.1016/j.bbmt.2016.06.005.

PMID:
    27288956
    [PubMed - in process]
Related citations


Do adults aged 70 years or older with acute myeloid leukemia benefit from allogeneic hematopoietic cell transplantation?
Rashidi A, DiPersio JF, Westervelt P, Vij R, Abboud CN, Romee R
Leukemia. 2016 Aug; 30(8)1797-9. doi: 10.1038/leu.2016.99.

PMID:
    27230239
    [PubMed - in process]
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