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Faculty Physicians

John F. DiPersio, MD, PhD

Virginia E. and Samuel J Golman Endowed Professorship of Medicine, Pathology & Immunology
Professor, Pediatrics
Professor, Pathology
Chief, Division of Oncology
Deputy Director, Siteman Cancer Center

Specialty Areas

Bone Marrow Transplant
Hematology
Leukemia
Hematologic Malignancies
Gene Therapy

Board Certifications

Hematology
Internal Medicine
Oncology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Hematology, oncology, bone marrow transplantation, hematopoietic stem cell transplantation, molecular biology, cellular biology, leukemia, MDS, aplastic anemia

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Siteman Cancer Center

4921 Parkview Place
St. Louis, MO 63110
Phone: 314-747-7222

Suite: B
Floor: 7
Office Phone: 314-454-8304
Fax: 314-454-7551

Education

Education

Fellowship: Hematology & Oncology, UCLA School of Medicine, Los Angeles, CA 1987
Chief Resident: Internal Medicine, Parkland Memorial Hospital, Dallas, TX 1984
Residency: Internal Medicine, Parkland Memorial Hospital, Dallas, TX 1983
Ph.D.: Microbiology, University of Rochester School of Medicine, Rochester, NY 1980
Medical Degree: University Of Rochester School of Medicine, Rochester, NY 1980
B.A.: Biology, Williams College 1973

Publication & Research

Publication & Research

A study of high-dose lenalidomide induction and low-dose lenalidomide maintenance therapy for patients with hypomethylating agent refractory myelodysplastic syndrome.
Cherian MA, Tibes R, Gao F, Fletcher T, Fiala M, Uy GL, Westervelt P, Jacoby MA, Cashen AF, Stockerl-Goldstein K, DiPersio JF, Vij R
Leuk Lymphoma. 2016 Apr 27; 1-6.

PMID:
    27122296
    [PubMed - as supplied by publisher]
Related citations


Chemotherapy versus Hypomethylating Agents for the Treatment of Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndrome after Allogeneic Stem Cell Transplant.
Motabi IH, Ghobadi A, Liu J, Schroeder M, Abboud CN, Cashen AF, Stockler-Goldstein KE, Uy GL, Vij R, Westervelt P, DiPersio JF
Biol Blood Marrow Transplant. 2016 Mar 26; pii: S1083-8791(16)00192-0. doi: 10.1016/j.bbmt.2016.03.023.

PMID:
    27026249
    [PubMed - as supplied by publisher]
Related citations


The effect of FLT3-ITD and NPM1 mutation on survival in intensively treated elderly patients with cytogenetically normal acute myeloid leukemia.
Rashidi A, Wolach O, El-Jawahri A, Ho VT, DiPersio JF, Soiffer R, Stone RM, Chen YB
Leuk Lymphoma. 2016 Mar 22; 1-3.

PMID:
    27003236
    [PubMed - as supplied by publisher]
Related citations


Peritransplant Serum Albumin Decline Predicts Subsequent Severe Acute Graft-versus-Host Disease after Mucotoxic Myeloablative Conditioning.
Rashidi A, DiPersio JF, Westervelt P, Abboud CN, Schroeder MA, Cashen AF, Pusic I, Romee R
Biol Blood Marrow Transplant. 2016 Mar 14; pii: S1083-8791(16)00159-2. doi: 10.1016/j.bbmt.2016.03.010.

PMID:
    26988741
    [PubMed - as supplied by publisher]
Related citations


Steroids Versus Steroids Plus Additional Agent in Frontline Treatment of Acute Graft-versus-Host Disease: A Systematic Review and Meta-Analysis of Randomized Trials.
Rashidi A, DiPersio JF, Sandmaier BM, Colditz GA, Weisdorf DJ
Biol Blood Marrow Transplant. 2016 Mar 10; pii: S1083-8791(16)00150-6. doi: 10.1016/j.bbmt.2016.02.021.

PMID:
    26970383
    [PubMed - as supplied by publisher]
Related citations


High-throughput sequencing of cerebrospinal fluid for diagnosis of chronic Propionibacterium acnes meningitis in an allogeneic stem cell transplant recipient.
Wylie KM, Blanco-Guzman M, Wylie TN, Lawrence SJ, Ghobadi A, DiPersio JF, Storch GA
Transpl Infect Dis. 2016 Apr; 18(2)227-33. doi: 10.1111/tid.12512.

PMID:
    26895706
    [PubMed - in process]
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Targeting the leukemia-stroma interaction in acute myeloid leukemia: rationale and latest evidence.
Rashidi A, DiPersio JF
Ther Adv Hematol. 2016 Feb; 7(1)40-51. doi: 10.1177/2040620715619307.

PMID:
    26834953
    [PubMed]
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Ex Vivo and In Vivo Evaluation of Overexpressed VLA-4 in Multiple Myeloma Using LLP2A Imaging Agents.
Soodgupta D, Zhou H, Beaino W, Lu L, Rettig M, Snee M, Skeath J, DiPersio JF, Akers WJ, Laforest R, Anderson CJ, Tomasson MH, Shokeen M
J Nucl Med. 2016 Apr; 57(4)640-5. doi: 10.2967/jnumed.115.164624.

PMID:
    26742713
    [PubMed - in process]
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Patterns and functional implications of rare germline variants across 12 cancer types.
Lu C, Xie M, Wendl MC, Wang J, McLellan MD, Leiserson MD, Huang KL, Wyczalkowski MA, Jayasinghe R, Banerjee T, Ning J, Tripathi P, Zhang Q, Niu B, Ye K, Schmidt HK, Fulton RS, McMichael JF, Batra P, Kandoth C, Bharadwaj M, Koboldt DC, Miller CA, Kanchi KL, Eldred JM, Larson DE, Welch JS, You M, Ozenberger BA, Govindan R, Walter MJ, Ellis MJ, Mardis ER, Graubert TA, Dipersio JF, Ley TJ, Wilson RK, Goodfellow PJ, Raphael BJ, Chen F, Johnson KJ, Parvin JD, Ding L
Nat Commun. 2015 Dec 22; 610086. doi: 10.1038/ncomms10086.

PMID:
    26689913
    [PubMed - indexed for MEDLINE]
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A phase I study of carfilzomib for relapsed or refractory acute myeloid and acute lymphoblastic leukemia.
Wartman LD, Fiala MA, Fletcher T, Hawkins ER, Cashen A, DiPersio JF, Jacoby MA, Stockerl-Goldstein KE, Pusic I, Uy GL, Westervelt P, Vij R
Leuk Lymphoma. 2016 Mar; 57(3)728-30. doi: 10.3109/10428194.2015.1076930.

PMID:
    26674111
    [PubMed - in process]
Related citations


Phase-1/-2 study of pomalidomide in chronic GvHD.
Pusic I, Rettig MP, DiPersio JF, Bauer S, McFarland K, Gale RP, Pavletic SZ
Bone Marrow Transplant. 2016 Apr; 51(4)612-4. doi: 10.1038/bmt.2015.298.

PMID:
    26657832
    [PubMed - in process]
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Rapid expansion of preexisting nonleukemic hematopoietic clones frequently follows induction therapy for de novo AML.
Wong TN, Miller CA, Klco JM, Petti A, Demeter R, Helton NM, Li T, Fulton RS, Heath SE, Mardis ER, Westervelt P, DiPersio JF, Walter MJ, Welch JS, Graubert TA, Wilson RK, Ley TJ, Link DC
Blood. 2016 Feb 18; 127(7)893-7. doi: 10.1182/blood-2015-10-677021.

PMID:
    26631115
    [PubMed - in process]
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NCCN Oncology Research Program's Investigator Steering Committee and NCCN Best Practices Committee Molecular Profiling Surveys.
Kurzrock R, Colevas AD, Olszanski A, Akerley W, Arteaga CL, Carson WE 3rd, Clark JW, DiPersio JF, Ettinger DS, Morgan RJ Jr, Schwartzberg LS, Venook AP, Gocke CD, Tait J, Stewart FM
J Natl Compr Canc Netw. 2015 Nov; 13(11)1337-46.

PMID:
    26553764
    [PubMed - in process]
Related citations


Acute myeloid leukemia presenting with extensive bone marrow necrosis, leukemia cutis and testicular involvement: successful treatment with allogeneic hematopoietic stem cell transplantation.
Rashidi A, DiPersio JF, Westervelt P, Abboud CN, Romee R
Bone Marrow Transplant. 2016 Mar; 51(3)454-5. doi: 10.1038/bmt.2015.272.

PMID:
    26551781
    [PubMed - in process]
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Targeting CD123 in acute myeloid leukemia using a T-cell-directed dual-affinity retargeting platform.
Al-Hussaini M, Rettig MP, Ritchey JK, Karpova D, Uy GL, Eissenberg LG, Gao F, Eades WC, Bonvini E, Chichili GR, Moore PA, Johnson S, Collins L, DiPersio JF
Blood. 2016 Jan 7; 127(1)122-31. doi: 10.1182/blood-2014-05-575704.

PMID:
    26531164
    [PubMed - in process]
Related citations


Outcomes of Allogeneic Stem Cell Transplantation in Elderly Patients with Acute Myeloid Leukemia: A Systematic Review and Meta-analysis.
Rashidi A, Ebadi M, Colditz GA, DiPersio JF
Biol Blood Marrow Transplant. 2016 Apr; 22(4)651-7. doi: 10.1016/j.bbmt.2015.10.019.

PMID:
    26529178
    [PubMed - in process]
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The effect of donor characteristics on survival after unrelated donor transplantation for hematologic malignancy.
Kollman C, Spellman SR, Zhang MJ, Hassebroek A, Anasetti C, Antin JH, Champlin RE, Confer DL, DiPersio JF, Fernandez-Viña M, Hartzman RJ, Horowitz MM, Hurley CK, Karanes C, Maiers M, Mueller CR, Perales MA, Setterholm M, Woolfrey AE, Yu N, Eapen M
Blood. 2016 Jan 14; 127(2)260-7. doi: 10.1182/blood-2015-08-663823.

PMID:
    26527675
    [PubMed - in process]
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Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia.
Churpek JE, Pyrtel K, Kanchi KL, Shao J, Koboldt D, Miller CA, Shen D, Fulton R, O'Laughlin M, Fronick C, Pusic I, Uy GL, Braunstein EM, Levis M, Ross J, Elliott K, Heath S, Jiang A, Westervelt P, DiPersio JF, Link DC, Walter MJ, Welch J, Wilson R, Ley TJ, Godley LA, Graubert TA
Blood. 2015 Nov 26; 126(22)2484-90. doi: 10.1182/blood-2015-04-641100.

PMID:
    26492932
    [PubMed - indexed for MEDLINE]
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Targeting bone marrow lymphoid niches in acute lymphoblastic leukemia.
Uy GL, Hsu YM, Schmidt AP, Stock W, Fletcher TR, Trinkaus KM, Westervelt P, DiPersio JF, Link DC
Leuk Res. 2015 Dec; 39(12)1437-42. doi: 10.1016/j.leukres.2015.09.020.

PMID:
    26467815
    [PubMed - indexed for MEDLINE]
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Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia.
Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Helton NM, Duncavage EJ, Payton JE, Baty J, Heath SE, Griffith OL, Shen D, Hundal J, Chang GS, Fulton R, O'Laughlin M, Fronick C, Magrini V, Demeter RT, Larson DE, Kulkarni S, Ozenberger BA, Welch JS, Walter MJ, Graubert TA, Westervelt P, Radich JP, Link DC, Mardis ER, DiPersio JF, Wilson RK, Ley TJ
JAMA. 2015 Aug 25; 314(8)811-22. doi: 10.1001/jama.2015.9643.

PMID:
    26305651
    [PubMed - indexed for MEDLINE]
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