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Faculty Physicians

John Carl Morris, MD

Harvey A. and Dorismae Hacker Friedman Professor of Neurology
Professor, Pathology and Immunology
Director, Center for Aging
Director, Memory and Aging Project
Director, Alzheimer's Disease Research Center

Specialty Areas

Neurology - Adult
Memory Disorders and Diagnosis
Alzheimer's Disease
Dementia

Board Certifications

Internal Medicine
Neurology

Hospital Affiliations

Barnes-Jewish Hospital

Referral Information

Referred by Self or Referring Physician

Areas of Clinical Interest

Alzheimer's disease, dementia, geriatric neurology, neurodegenerative diseases, mild cognitive impairment, aging, cognitive function

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Memory Diagnostic Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: (314) 286-1967
Fax: (314) 286-1985
Email: morrisj@neuro.wustl.edu

Education

Education

Fellowship: Neuropharmacology, Washington University School of Medicine, St. Louis, Missouri 1985
Residency: Neuropathology, Cleveland Metropolitan General Hospital, Cleveland, Ohio 1982
Chief Residency: Neurology, Cleveland Metropolitan General Hospital, Cleveland, Ohio 1981
Residency: Internal Medicine, Akron General Medical Center, Akron, Ohio 1979
Medical Degree: University Of Rochester School of Medicine and Dentistry, Rochester, New York 1974
B.A.: Ohio Wesleyan University, Delaware, Ohio 1970

Publication & Research

Publication & Research

Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study.
Chatterjee P, Lim WL, Shui G, Gupta VB, James I, Fagan AM, Xiong C, Sohrabi HR, Taddei K, Brown BM, Benzinger T, Masters C, Snowden SG, Wenk MR, Bateman RJ, Morris JC, Martins RN
J Alzheimers Dis. 2016 Jan 21;

PMID:
    26836186
    [PubMed - as supplied by publisher]
Related citations


Local and distributed PiB accumulation associated with development of preclinical Alzheimer's disease.
Brier MR, McCarthy JE, Benzinger TL, Stern A, Su Y, Friedrichsen KA, Morris JC, Ances BM, Vlassenko AG
Neurobiol Aging. 2016 Feb; 38104-11. doi: 10.1016/j.neurobiolaging.2015.10.025.

PMID:
    26827648
    [PubMed - in process]
Related citations


Activating protein phosphatase 2A (PP2A) enhances tristetraprolin (TTP) anti-inflammatory function in A549 lung epithelial cells.
Rahman MM, Rumzhum NN, Hansbro PM, Morris JC, Clark AR, Verrills NM, Ammit AJ
Cell Signal. 2016 Jan 26; 28(4)325-334. doi: 10.1016/j.cellsig.2016.01.009.

PMID:
    26820662
    [PubMed - as supplied by publisher]
Related citations


Partisan Politics or Public-Health Need? An empirical analysis of state choice during initial implementation of the Affordable Care Act.
Mayer M, Kenter R, Morris JC
Politics Life Sci. 2015 Fall; 34(2)44-51.

PMID:
    26742593
    [PubMed - in process]
Related citations


Synthesis of highly enantio-enriched stereoisomers of hydroxy-GR24.
Morris JC, McErlean CS
Org Biomol Chem. 2016 Jan 28; 14(4)1236-8. doi: 10.1039/c5ob02349a.

PMID:
    26691225
    [PubMed - in process]
Related citations


Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss.
Benitez BA, Cairns NJ, Schmidt RE, Morris JC, Norton JB, Cruchaga C, Sands MS
Acta Neuropathol Commun. 2015 Nov 26; 3(1)73. doi: 10.1186/s40478-015-0256-5.

PMID:
    26610600
    [PubMed - in process]
Related citations


A Century of Hyperthyroidism at Mayo Clinic.
Smallridge RC, Morris JC
Mayo Clin Proc. 2016 Jan; 91(1)e7-e12. doi: 10.1016/j.mayocp.2015.09.016.

PMID:
    26602598
    [PubMed - in process]
Related citations


Diagnostic accuracy of thyroid nodule growth to predict malignancy in thyroid nodules with benign cytology: Systematic review and meta-analysis.
Singh Ospina N, Maraka S, Espinosa De Ycaza A, O'Keeffe D, Brito JP, Gionfriddo MR, Castro MR, Morris JC, Erwin P, Montori VM
Clin Endocrinol (Oxf). 2015 Nov 12; doi: 10.1111/cen.12975.

PMID:
    26562828
    [PubMed - as supplied by publisher]
Related citations


A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin.
Deming Y, Xia J, Cai Y, Lord J, Holmans P, Bertelsen S, Holtzman D, Morris JC, Bales K, Pickering EH, Kauwe J, Goate A, Cruchaga C, Alzheimer's Disease Neuroimaging Initiative (ADNI)
Neurobiol Aging. 2016 Jan; 37208.e1-9. doi: 10.1016/j.neurobiolaging.2015.09.009.

PMID:
    26545630
    [PubMed - in process]
Related citations


Synthesis and biological evaluation of analogs of AAL(S) for use as ceramide synthase 1 inhibitors.
Toop HD, Don AS, Morris JC
Org Biomol Chem. 2015 Dec 28; 13(48)11593-6. doi: 10.1039/c5ob01931a.

PMID:
    26535908
    [PubMed - in process]
Related citations


Attitudes of Research Participants and the General Public Regarding Disclosure of Alzheimer Disease Research Results.
Gooblar J, Roe CM, Selsor NJ, Gabel MJ, Morris JC
JAMA Neurol. 2015 Dec 1; 72(12)1484-90. doi: 10.1001/jamaneurol.2015.2875.

PMID:
    26501506
    [PubMed - in process]
Related citations


Neuropsychological Markers of Cognitive Decline in Persons With Alzheimer Disease Neuropathology.
Hassenstab J, Monsell SE, Mock C, Roe CM, Cairns NJ, Morris JC, Kukull W
J Neuropathol Exp Neurol. 2015 Nov; 74(11)1086-92. doi: 10.1097/NEN.0000000000000254.

PMID:
    26469250
    [PubMed - indexed for MEDLINE]
Related citations


90Y-daclizumab, an anti-CD25 monoclonal antibody, provided responses in 50% of patients with relapsed Hodgkin's lymphoma.
Janik JE, Morris JC, O'Mahony D, Pittaluga S, Jaffe ES, Redon CE, Bonner WM, Brechbiel MW, Paik CH, Whatley M, Chen C, Lee JH, Fleisher TA, Brown M, White JD, Stewart DM, Fioravanti S, Lee CC, Goldman CK, Bryant BR, Junghans RP, Carrasquillo JA, Worthy T, Corcoran E, Conlon KC, Waldmann TA
Proc Natl Acad Sci U S A. 2015 Oct 20; 112(42)13045-50. doi: 10.1073/pnas.1516107112.

PMID:
    26438866
    [PubMed - in process]
Related citations


CAP-advancing the evaluation of preclinical Alzheimer disease treatments.
Reiman EM, Langbaum JB, Tariot PN, Lopera F, Bateman RJ, Morris JC, Sperling RA, Aisen PS, Roses AD, Welsh-Bohmer KA, Carrillo MC, Weninger S
Nat Rev Neurol. 2016 Jan; 12(1)56-61. doi: 10.1038/nrneurol.2015.177.

PMID:
    26416539
    [PubMed - in process]
Related citations


Alzheimer Disease Cerebrospinal Fluid Biomarkers Moderate Baseline Differences and Predict Longitudinal Change in Attentional Control and Episodic Memory Composites in the Adult Children Study.
Aschenbrenner AJ, Balota DA, Fagan AM, Duchek JM, Benzinger TL, Morris JC
J Int Neuropsychol Soc. 2015 Sep; 21(8)573-83. doi: 10.1017/S1355617715000776.

PMID:
    26416094
    [PubMed - in process]
Related citations


Study of amyloid-β peptide functional brain networks in AD, MCI and HC.
Jiang J, Duan H, Huang Z, Yu Z, Alzheimer's Disease Neuroimaging Initiative
Biomed Mater Eng. 2015; 26 Suppl 1S2197-205. doi: 10.3233/BME-151525.

PMID:
    26405999
    [PubMed - in process]
Related citations


Common Variants in PLD3 and Correlation to Amyloid-Related Phenotypes in Alzheimer's Disease.
Wang C, Tan L, Wang HF, Yu WJ, Liu Y, Jiang T, Tan MS, Hao XK, Zhang DQ, Yu JT, Alzheimer's Disease Neuroimaging Initiative
J Alzheimers Dis. 2015; 46(2)491-5. doi: 10.3233/JAD-150110.

PMID:
    26402410
    [PubMed - in process]
Related citations


Identification of Conversion from Normal Elderly Cognition to Alzheimer's Disease using Multimodal Support Vector Machine.
Zhan Y, Chen K, Wu X, Zhang D, Zhang J, Yao L, Guo X, Alzheimer’s Disease Neuroimaging Initiative
J Alzheimers Dis. 2015; 47(4)1057-67. doi: 10.3233/JAD-142820.

PMID:
    26401783
    [PubMed - in process]
Related citations


Tau and Amyloid-β Cerebrospinal Fluid Biomarkers have Differential Relationships with Cognition in Mild Cognitive Impairment.
Malpas CB, Saling MM, Velakoulis D, Desmond P, O'Brien TJ, Alzheimer's Disease Neuroimaging Initiative
J Alzheimers Dis. 2015; 47(4)965-75. doi: 10.3233/JAD-142643.

PMID:
    26401775
    [PubMed - in process]
Related citations


Applying Automated MR-Based Diagnostic Methods to the Memory Clinic: A Prospective Study.
Klöppel S, Peter J, Ludl A, Pilatus A, Maier S, Mader I, Heimbach B, Frings L, Egger K, Dukart J, Schroeter ML, Perneczky R, Häussermann P, Vach W, Urbach H, Teipel S, Hüll M, Abdulkadir A, Alzheimer’s Disease Neuroimaging Initiative
J Alzheimers Dis. 2015; 47(4)939-54. doi: 10.3233/JAD-150334.

PMID:
    26401773
    [PubMed - in process]
Related citations