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John Carl Morris, MD

Harvey A. and Dorismae Hacker Friedman Professor of Neurology
Professor, Pathology and Immunology
Director, Center for Aging
Director, Memory and Aging Project
Director, Alzheimer's Disease Research Center

Specialty Areas

Neurology - Adult
Memory Disorders and Diagnosis
Alzheimer's Disease
Dementia

Board Certifications

Internal Medicine
Neurology

Hospital Affiliations

Barnes-Jewish Hospital

Referral Information

Referred by Self or Referring Physician

Areas of Clinical Interest

Alzheimer's disease, dementia, geriatric neurology, neurodegenerative diseases, mild cognitive impairment, aging, cognitive function

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Memory Diagnostic Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: (314) 286-1967
Fax: (314) 286-1985
Email: morrisj@neuro.wustl.edu

Education

Education

Fellowship: Neuropharmacology, Washington University School of Medicine, St. Louis, Missouri 1985
Residency: Neuropathology, Cleveland Metropolitan General Hospital, Cleveland, Ohio 1982
Chief Residency: Neurology, Cleveland Metropolitan General Hospital, Cleveland, Ohio 1981
Residency: Internal Medicine, Akron General Medical Center, Akron, Ohio 1979
Medical Degree: University Of Rochester School of Medicine and Dentistry, Rochester, New York 1974
B.A.: Ohio Wesleyan University, Delaware, Ohio 1970

Publication & Research

Publication & Research

Mood Changes in Cognitively Normal Older Adults are Linked to Alzheimer Disease Biomarker Levels.
Babulal GM, Ghoshal N, Head D, Vernon EK, Holtzman DM, Benzinger TL, Fagan AM, Morris JC, Roe CM
Am J Geriatr Psychiatry. 2016 Apr 19; pii: S1064-7481(16)30082-3. doi: 10.1016/j.jagp.2016.04.004.

PMID:
    27426238
    [PubMed - as supplied by publisher]
Related citations


Imaging and cerebrospinal fluid biomarkers in early preclinical Alzheimer disease.
Vlassenko AG, McCue L, Jasielec MS, Su Y, Gordon BA, Xiong C, Holtzman DM, Benzinger TL, Morris JC, Fagan AM
Ann Neurol. 2016 Jul 11; doi: 10.1002/ana.24719.

PMID:
    27398953
    [PubMed - as supplied by publisher]
Related citations


Type 2 diabetes mellitus is associated with brain atrophy and hypometabolism in the ADNI cohort.
Li W, Risacher SL, Huang E, Saykin AJ, Alzheimer's Disease Neuroimaging Initiative
Neurology. 2016 Jul 6; pii: 10.1212/WNL.0000000000002950.

PMID:
    27385744
    [PubMed - as supplied by publisher]
Related citations


Polygenic risk of Alzheimer disease is associated with early- and late-life processes.
Mormino EC, Sperling RA, Holmes AJ, Buckner RL, De Jager PL, Smoller JW, Sabuncu MR, Alzheimer's Disease Neuroimaging Initiative
Neurology. 2016 Jul 6; pii: 10.1212/WNL.0000000000002922.

PMID:
    27385740
    [PubMed - as supplied by publisher]
Related citations


Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer's disease.
Muenchhoff J, Poljak A, Thalamuthu A, Gupta VB, Chatterjee P, Raftery M, Masters CL, Morris JC, Bateman RJ, Fagan AM, Martins RN, Sachdev PS
Sci Rep. 2016 Jul 6; 629078. doi: 10.1038/srep29078.

PMID:
    27381087
    [PubMed - in process]
Related citations


NIA-AA staging of preclinical Alzheimer disease: discordance and concordance of CSF and imaging biomarkers.
Vos SJ, Gordon BA, Su Y, Visser PJ, Holtzman DM, Morris JC, Fagan AM, Benzinger TL
Neurobiol Aging. 2016 Aug; 441-8. doi: 10.1016/j.neurobiolaging.2016.03.025.

PMID:
    27318129
    [PubMed - in process]
Related citations


The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging.
Gordon BA, Friedrichsen K, Brier M, Blazey T, Su Y, Christensen J, Aldea P, McConathy J, Holtzman DM, Cairns NJ, Morris JC, Fagan AM, Ances BM, Benzinger TL
Brain. 2016 Jun 10; pii: aww139.

PMID:
    27286736
    [PubMed - as supplied by publisher]
Related citations


Development of Simplified Heterocyclic Acetogenin Analogues as Potent and Selective Trypanosoma brucei Inhibitors.
Florence GJ, Fraser AL, Gould ER, King EF, Menzies SK, Morris JC, Thomson MI, Tulloch LB, Zacharova MK, Smith TK
ChemMedChem. 2016 Jul 19; 11(14)1503-6. doi: 10.1002/cmdc.201600210.

PMID:
    27283448
    [PubMed - in process]
Related citations


Certified normal: Alzheimer's disease biomarkers and normative estimates of cognitive functioning.
Hassenstab J, Chasse R, Grabow P, Benzinger TL, Fagan AM, Xiong C, Jasielec M, Grant E, Morris JC
Neurobiol Aging. 2016 Jul; 4323-33. doi: 10.1016/j.neurobiolaging.2016.03.014.

PMID:
    27255812
    [PubMed - in process]
Related citations


Comparison of a single-channel EEG sleep study to polysomnography.
Lucey BP, Mcleland JS, Toedebusch CD, Boyd J, Morris JC, Landsness EC, Yamada K, Holtzman DM
J Sleep Res. 2016 Jun 2; doi: 10.1111/jsr.12417.

PMID:
    27252090
    [PubMed - as supplied by publisher]
Related citations


Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer's disease cohorts.
Tan L, Wang HF, Tan MS, Tan CC, Zhu XC, Miao D, Yu WJ, Jiang T, Tan L, Yu JT, Alzheimer’s Disease Neuroimaging Initiative
Sci Rep. 2016 May 27; 626027. doi: 10.1038/srep26027.

PMID:
    27229352
    [PubMed - in process]
Related citations


New drugs for medullary thyroid cancer: new promises?
Spitzweg C, Morris JC, Bible KC
Endocr Relat Cancer. 2016 Jun; 23(6)R287-97. doi: 10.1530/ERC-16-0104.

PMID:
    27185870
    [PubMed - in process]
Related citations


Tau and Aβ imaging, CSF measures, and cognition in Alzheimer's disease.
Brier MR, Gordon B, Friedrichsen K, McCarthy J, Stern A, Christensen J, Owen C, Aldea P, Su Y, Hassenstab J, Cairns NJ, Holtzman DM, Fagan AM, Morris JC, Benzinger TL, Ances BM
Sci Transl Med. 2016 May 11; 8(338)338ra66. doi: 10.1126/scitranslmed.aaf2362.

PMID:
    27169802
    [PubMed - in process]
Related citations


Accelerating rates of cognitive decline and imaging markers associated with β-amyloid pathology.
Insel PS, Mattsson N, Mackin RS, Schöll M, Nosheny RL, Tosun D, Donohue MC, Aisen PS, Jagust WJ, Weiner MW, Alzheimer's Disease Neuroimaging Initiative
Neurology. 2016 May 17; 86(20)1887-96. doi: 10.1212/WNL.0000000000002683.

PMID:
    27164667
    [PubMed - in process]
Related citations


Prognosis of patients with benign thyroid nodules: a population-based study.
Singh Ospina N, Maraka S, Espinosa de Ycaza AE, Brito JP, Castro MR, Morris JC, Montori VM
Endocrine. 2016 May 3;

PMID:
    27142412
    [PubMed - as supplied by publisher]
Related citations


Amyloid Imaging, Cerebrospinal Fluid Biomarkers Predict Driving Performance Among Cognitively Normal Individuals.
Roe CM, Barco PP, Head DM, Ghoshal N, Selsor N, Babulal GM, Fierberg R, Vernon EK, Shulman N, Johnson A, Fague S, Xiong C, Grant EA, Campbell A, Ott BR, Holtzman DM, Benzinger TL, Fagan AM, Carr DB, Morris JC
Alzheimer Dis Assoc Disord. 2016 Apr 28;

PMID:
    27128959
    [PubMed - as supplied by publisher]
Related citations


The impact of PICALM genetic variations on reserve capacity of posterior cingulate in AD continuum.
Xu W, Wang HF, Tan L, Tan MS, Tan CC, Zhu XC, Miao D, Yu WJ, Jiang T, Tan L, Yu JT, Alzheimer’s Disease Neuroimaging Initiative Group
Sci Rep. 2016 Apr 27; 624480. doi: 10.1038/srep24480.

PMID:
    27117083
    [PubMed - in process]
Related citations


Cerebrospinal Fluid Biomarkers and Reserve Variables as Predictors of Future "Non-Cognitive" Outcomes of Alzheimer's Disease.
Ingber AP, Hassenstab J, Fagan AM, Benzinger TL, Grant EA, Holtzman DM, Morris JC, Roe CM
J Alzheimers Dis. 2016 Apr 16; 52(3)1055-64. doi: 10.3233/JAD-150478.

PMID:
    27104893
    [PubMed - in process]
Related citations


Development of novel PP2A activators for use in the treatment of acute myeloid leukaemia.
Toop HD, Dun MD, Ross BK, Flanagan HM, Verrills NM, Morris JC
Org Biomol Chem. 2016 May 18; 14(20)4605-16. doi: 10.1039/c6ob00556j.

PMID:
    27102578
    [PubMed - in process]
Related citations


Diagnostic accuracy of ultrasound-guided fine needle aspiration biopsy for thyroid malignancy: systematic review and meta-analysis.
Singh Ospina N, Brito JP, Maraka S, Espinosa de Ycaza AE, Rodriguez-Gutierrez R, Gionfriddo MR, Castaneda-Guarderas A, Benkhadra K, Al Nofal A, Erwin P, Morris JC, Castro MR, Montori VM
Endocrine. 2016 Apr 12;

PMID:
    27071659
    [PubMed - as supplied by publisher]
Related citations