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John Carl Morris, MD

Harvey A. and Dorismae Hacker Friedman Professor of Neurology
Professor, Pathology and Immunology
Director, Center for Aging
Director, Memory and Aging Project
Director, Alzheimer's Disease Research Center

Specialty Areas

Neurology - Adult
Memory Disorders and Diagnosis
Alzheimer's Disease
Dementia

Board Certifications

Internal Medicine
Neurology

Hospital Affiliations

Barnes-Jewish Hospital

Referral Information

Referred by Self or Referring Physician

Areas of Clinical Interest

Alzheimer's disease, dementia, geriatric neurology, neurodegenerative diseases, mild cognitive impairment, aging, cognitive function

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Memory Diagnostic Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: (314) 286-1967
Fax: (314) 286-1985
Email: morrisj@neuro.wustl.edu

Education

Education

Fellowship: Neuropharmacology, Washington University School of Medicine, St. Louis, Missouri 1985
Residency: Neuropathology, Cleveland Metropolitan General Hospital, Cleveland, Ohio 1982
Chief Residency: Neurology, Cleveland Metropolitan General Hospital, Cleveland, Ohio 1981
Residency: Internal Medicine, Akron General Medical Center, Akron, Ohio 1979
Medical Degree: University Of Rochester School of Medicine and Dentistry, Rochester, New York 1974
B.A.: Ohio Wesleyan University, Delaware, Ohio 1970

Publication & Research

Publication & Research

Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease.
Ng KP, Pascoal TA, Mathotaarachchi S, Chung CO, Benedet AL, Shin M, Kang MS, Li X, Ba M, Kandiah N, Rosa-Neto P, Gauthier S, Alzheimer's Disease Neuroimaging Initiative.
Neurology. 2017 Apr 12; pii: 10.1212/WNL.0000000000003916. doi: 10.1212/WNL.0000000000003916.

PMID:
    28404803
    [PubMed - as supplied by publisher]
Related citations


Tau-PET Binding Distinguishes Patients With Early-stage Posterior Cortical Atrophy From Amnestic Alzheimer Disease Dementia.
Day GS, Gordon BA, Jackson K, Christensen JJ, Rosana Ponisio M, Su Y, Ances BM, Benzinger TL, Morris JC
Alzheimer Dis Assoc Disord. 2017 Apr 7; doi: 10.1097/WAD.0000000000000196.

PMID:
    28394771
    [PubMed - as supplied by publisher]
Related citations


A Naturalistic Study of Driving Behavior in Older Adults and Preclinical Alzheimer Disease.
Babulal GM, Stout SH, Benzinger TL, Ott BR, Carr DB, Webb M, Traub CM, Addison A, Morris JC, Warren DK, Roe CM
J Appl Gerontol. 2017 Jan 1; 733464817690679. doi: 10.1177/0733464817690679.

PMID:
    28380718
    [PubMed - as supplied by publisher]
Related citations


A Phase Ib Study of the Dual PI3K/mTOR Inhibitor Dactolisib (BEZ235) Combined with Everolimus in Patients with Advanced Solid Malignancies.
Wise-Draper TM, Moorthy G, Salkeni MA, Karim NA, Thomas HE, Mercer CA, Beg MS, O'Gara S, Olowokure O, Fathallah H, Kozma SC, Thomas G, Rixe O, Desai P, Morris JC
Target Oncol. 2017 Mar 29; doi: 10.1007/s11523-017-0482-9.

PMID:
    28357727
    [PubMed - as supplied by publisher]
Related citations


pH Regulation in Glycosomes of Procyclic Form <i>Trypanosoma brucei</i>.
Lin S, Voyton C, Morris MT, Ackroyd PC, Morris JC, Christensen KA
J Biol Chem. 2017 Mar 27; pii: jbc.M117.784173. doi: 10.1074/jbc.M117.784173.

PMID:
    28348078
    [PubMed - as supplied by publisher]
Related citations


Adding Recognition Discriminability Index to the Delayed Recall Is Useful to Predict Conversion from Mild Cognitive Impairment to Alzheimer's Disease in the Alzheimer's Disease Neuroimaging Initiative.
Russo MJ, Campos J, Vázquez S, Sevlever G, Allegri RF, Alzheimer's Disease Neuroimaging Initiative.
Front Aging Neurosci. 2017; 946. doi: 10.3389/fnagi.2017.00046.

PMID:
    28344552
    [PubMed - in process]
Related citations


Construction and Analysis of Weighted Brain Networks from SICE for the Study of Alzheimer's Disease.
Munilla J, Ortiz A, Górriz JM, Ramírez J, Alzheimer's Disease Neuroimaging Initiative.
Front Neuroinform. 2017; 1119. doi: 10.3389/fninf.2017.00019.

PMID:
    28344551
    [PubMed - in process]
Related citations


Regulation of the nitric oxide oxidase activity of myeloperoxidase by pharmacological agents.
Maiocchi SL, Morris JC, Rees MD, Thomas SR
Biochem Pharmacol. 2017 Mar 24; pii: S0006-2952(17)30162-4. doi: 10.1016/j.bcp.2017.03.016.

PMID:
    28344126
    [PubMed - as supplied by publisher]
Related citations


Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials.
Weiner MW, Veitch DP, Aisen PS, Beckett LA, Cairns NJ, Green RC, Harvey D, Jack CR Jr, Jagust W, Morris JC, Petersen RC, Saykin AJ, Shaw LM, Toga AW, Trojanowski JQ, Alzheimer's Disease Neuroimaging Initiative.
Alzheimers Dement. 2017 Apr; 13(4)e1-e85. doi: 10.1016/j.jalz.2016.11.007.

PMID:
    28342697
    [PubMed - in process]
Related citations


Expression of PD-1 and PD-L1 in anaplastic thyroid cancer patients treated with multimodal therapy: results from a retrospective study.
Chintakuntlawar AV, Rumilla KM, Smith CY, Jenkins SM, Foote RL, Kasperbauer JL, Morris JC, Ryder M, Alsidawi S, Hilger C, Bible KC
J Clin Endocrinol Metab. 2017 Mar 7; doi: 10.1210/jc.2016-3756.

PMID:
    28324060
    [PubMed - as supplied by publisher]
Related citations


Mining Outcome-relevant Brain Imaging Genetic Associations via Three-way Sparse Canonical Correlation Analysis in Alzheimer's Disease.
Hao X, Li C, Du L, Yao X, Yan J, Risacher SL, Saykin AJ, Shen L, Zhang D, Alzheimer’s Disease Neuroimaging Initiative.
Sci Rep. 2017 Mar 14; 744272. doi: 10.1038/srep44272.

PMID:
    28291242
    [PubMed - in process]
Related citations


Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.
Deming Y, Li Z, Kapoor M, Harari O, Del-Aguila JL, Black K, Carrell D, Cai Y, Fernandez MV, Budde J, Ma S, Saef B, Howells B, Huang KL, Bertelsen S, Fagan AM, Holtzman DM, Morris JC, Kim S, Saykin AJ, De Jager PL, Albert M, Moghekar A, O'Brien R, Riemenschneider M, Petersen RC, Blennow K, Zetterberg H, Minthon L, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Schellenberg G, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Peskind ER, Li G, Di Narzo AF, Alzheimer’s Disease Neuroimaging Initiative (ADNI)., Alzheimer Disease Genetic Consortium (ADGC)., Kauwe JS, Goate AM, Cruchaga C
Acta Neuropathol. 2017 May; 133(5)839-856. doi: 10.1007/s00401-017-1685-y.

PMID:
    28247064
    [PubMed - indexed for MEDLINE]
Related citations


Differentiating cognitive impairment due to corticobasal degeneration and Alzheimer disease.
Day GS, Lim TS, Hassenstab J, Goate AM, Grant EA, Roe CM, Cairns NJ, Morris JC
Neurology. 2017 Mar 28; 88(13)1273-1281. doi: 10.1212/WNL.0000000000003770.

PMID:
    28235814
    [PubMed - in process]
Related citations


The protumorigenic potential of FTY720 by promoting extramedullary hematopoiesis and MDSC accumulation.
Li Y, Zhou T, Wang Y, Ning C, Lv Z, Han G, Morris JC, Taylor EN, Wang R, Xiao H, Hou C, Ma Y, Shen B, Feng J, Guo R, Li Y, Chen G
Oncogene. 2017 Feb 20; doi: 10.1038/onc.2017.2.

PMID:
    28218904
    [PubMed - as supplied by publisher]
Related citations


Pediatric, Adolescent, and Young Adult Thyroid Carcinoma Harbors Frequent and Diverse Targetable Genomic Alterations, Including Kinase Fusions.
Vanden Borre P, Schrock AB, Anderson PM, Morris JC 3rd, Heilmann AM, Holmes O, Wang K, Johnson A, Waguespack SG, Ou SI, Khan S, Fung KM, Stephens PJ, Erlich RL, Miller VA, Ross JS, Ali SM
Oncologist. 2017 Mar; 22(3)255-263. doi: 10.1634/theoncologist.2016-0279.

PMID:
    28209747
    [PubMed - in process]
Related citations


Process Dissociation Analyses of Memory Changes in Healthy Aging, Preclinical, and Very Mild Alzheimer Disease: Evidence for Isolated Recollection Deficits.
Millar PR, Balota DA, Maddox GB, Duchek JM, Aschenbrenner AJ, Fagan AM, Benzinger TL, Morris JC
Neuropsychology. 2017 Feb 16; doi: 10.1037/neu0000352.

PMID:
    28206782
    [PubMed - as supplied by publisher]
Related citations


Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, Foroud TM, Friedland RP, Goate AM, Graff-Radford NR, Hendrie H, Hall KS, Hamilton-Nelson KL, Inzelberg R, Kamboh MI, Kauwe JS, Kukull WA, Kunkle BW, Kuwano R, Larson EB, Logue MW, Manly JJ, Martin ER, Montine TJ, Mukherjee S, Naj A, Reiman EM, Reitz C, Sherva R, St George-Hyslop PH, Thornton T, Younkin SG, Vardarajan BN, Wang LS, Wendlund JR, Winslow AR, Alzheimer's Disease Genetics Consortium., Haines J, Mayeux R, Pericak-Vance MA, Schellenberg G, Lunetta KL, Farrer LA
Alzheimers Dement. 2017 Feb 7; pii: S1552-5260(17)30003-1. doi: 10.1016/j.jalz.2016.12.012.

PMID:
    28183528
    [PubMed - as supplied by publisher]
Related citations


Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.
Batson J, Toop HD, Redondo C, Babaei-Jadidi R, Chaikuad A, Wearmouth SF, Gibbons B, Allen C, Tallant C, Zhang J, Du C, Hancox JC, Hawtrey T, Da Rocha J, Griffith R, Knapp S, Bates DO, Morris JC
ACS Chem Biol. 2017 Mar 17; 12(3)825-832. doi: 10.1021/acschembio.6b01048.

PMID:
    28135068
    [PubMed - in process]
Related citations


Antiparasitic lethality of sulfonamidebenzamides in kinetoplastids.
Hackler A, Patrick SL, Kahney EW, Flaherty DP, Sharlow ER, Morris JC, Golden JE
Bioorg Med Chem Lett. 2017 Feb 15; 27(4)755-758. doi: 10.1016/j.bmcl.2017.01.043.

PMID:
    28119024
    [PubMed - in process]
Related citations


American Thyroid Association Guidelines on the Management of Thyroid Nodules and Differentiated Thyroid Cancer Task Force Review and Recommendation on the Proposed Renaming of Encapsulated Follicular Variant Papillary Thyroid Carcinoma Without Invasion to Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features.
Haugen BR, Sawka AM, Alexander EK, Bible KC, Caturegli P, Doherty GM, Mandel SJ, Morris JC, Nassar A, Pacini F, Schlumberger M, Schuff K, Sherman SI, Somerset H, Sosa JA, Steward DL, Wartofsky L, Williams MD
Thyroid. 2017 Apr; 27(4)481-483. doi: 10.1089/thy.2016.0628.

PMID:
    28114862
    [PubMed - in process]
Related citations