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John Carl Morris, MD

Harvey A. and Dorismae Hacker Friedman Professor of Neurology
Professor, Pathology and Immunology
Director, Center for Aging
Director, Memory and Aging Project
Director, Alzheimer's Disease Research Center

Specialty Areas

Neurology - Adult
Memory Disorders and Diagnosis
Alzheimer's Disease
Dementia

Board Certifications

Internal Medicine
Neurology

Hospital Affiliations

Barnes-Jewish Hospital

Referral Information

Referred by Self or Referring Physician

Areas of Clinical Interest

Alzheimer's disease, dementia, geriatric neurology, neurodegenerative diseases, mild cognitive impairment, aging, cognitive function

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Memory Diagnostic Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: (314) 286-1967
Fax: (314) 286-1985
Email: morrisj@neuro.wustl.edu

Education

Education

Fellowship: Neuropharmacology, Washington University School of Medicine, St. Louis, Missouri 1985
Residency: Neuropathology, Cleveland Metropolitan General Hospital, Cleveland, Ohio 1982
Chief Residency: Neurology, Cleveland Metropolitan General Hospital, Cleveland, Ohio 1981
Residency: Internal Medicine, Akron General Medical Center, Akron, Ohio 1979
Medical Degree: University Of Rochester School of Medicine and Dentistry, Rochester, New York 1974
B.A.: Ohio Wesleyan University, Delaware, Ohio 1970

Publication & Research

Publication & Research

Distinct cytokine profiles in human brains resilient to Alzheimer's pathology.
Barroeta-Espar I, Weinstock LD, Perez-Nievas BG, Meltzer AC, Tick-Chong MS, Amaral AC, Murray ME, Moulder KL, Morris JC, Cairns NJ, Parisi JE, Lowe VJ, Petersen RC, Kofler J, Ikonomovic MD, López O, Klunk WE, Mayeux RP, Frosch MP, Wood LB, Gomez-Isla T
Neurobiol Dis. 2018 Oct 15; pii: S0969-9961(18)30713-7. doi: 10.1016/j.nbd.2018.10.009.

PMID:
    30336198
    [PubMed - as supplied by publisher]
Related citations


Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative.
Veitch DP, Weiner MW, Aisen PS, Beckett LA, Cairns NJ, Green RC, Harvey D, Jack CR Jr, Jagust W, Morris JC, Petersen RC, Saykin AJ, Shaw LM, Toga AW, Trojanowski JQ, Alzheimer's Disease Neuroimaging Initiative.
Alzheimers Dement. 2018 Oct 12; pii: S1552-5260(18)33514-3. doi: 10.1016/j.jalz.2018.08.005.

PMID:
    30321505
    [PubMed - as supplied by publisher]
Related citations


Patients with BRCA mutations have superior outcomes after intraperitoneal chemotherapy in optimally resected high grade ovarian cancer.
Naumann RW, Morris JC, Tait DL, Higgins RV, Crane EK, Drury LK, Amacker-North L, Templin M, Brown J
Gynecol Oncol. 2018 Oct 8; pii: S0090-8258(18)31282-4. doi: 10.1016/j.ygyno.2018.10.003.

PMID:
    30309722
    [PubMed - as supplied by publisher]
Related citations


Incident cognitive impairment: longitudinal changes in molecular, structural and cognitive biomarkers.
Roe CM, Ances BM, Head D, Babulal GM, Stout SH, Grant EA, Hassenstab J, Xiong C, Holtzman DM, Benzinger TLS, Schindler SE, Fagan AM, Morris JC
Brain. 2018 Oct 9; doi: 10.1093/brain/awy244.

PMID:
    30304397
    [PubMed - as supplied by publisher]
Related citations


Widespread distribution of tauopathy in preclinical Alzheimer's disease.
Schultz SA, Gordon BA, Mishra S, Su Y, Perrin RJ, Cairns NJ, Morris JC, Ances BM, Benzinger TLS
Neurobiol Aging. 2018 Sep 1; 72177-185. doi: 10.1016/j.neurobiolaging.2018.08.022.

PMID:
    30292840
    [PubMed - as supplied by publisher]
Related citations


Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease.
Müller S, Preische O, Sohrabi HR, Gräber S, Jucker M, Ringman JM, Martins RN, McDade E, Schofield PR, Ghetti B, Rossor M, Fox NN, Graff-Radford NR, Levin J, Danek A, Vöglein J, Salloway S, Xiong C, Benzinger T, Buckles V, Masters CL, Sperling R, Bateman RJ, Morris JC, Laske C, Dominantly Inherited Alzheimer Network (DIAN).
Alzheimers Dement. 2018 Sep 21; pii: S1552-5260(18)33248-5. doi: 10.1016/j.jalz.2018.06.3059.

PMID:
    30266303
    [PubMed - as supplied by publisher]
Related citations


Non-beta-amyloid/tau cerebrospinal fluid markers inform staging and progression in Alzheimer's disease.
Gangishetti U, Christina Howell J, Perrin RJ, Louneva N, Watts KD, Kollhoff A, Grossman M, Wolk DA, Shaw LM, Morris JC, Trojanowski JQ, Fagan AM, Arnold SE, Hu WT
Alzheimers Res Ther. 2018 Sep 25; 10(1)98. doi: 10.1186/s13195-018-0426-3.

PMID:
    30253800
    [PubMed - in process]
Related citations


Relative neuron loss in hippocampal sclerosis of aging and Alzheimer disease.
Ihara R, Vincent BD, Baxter MR, Franklin EE, Hassenstab JJ, Xiong C, Morris JC, Cairns NJ
Ann Neurol. 2018 Sep 24; doi: 10.1002/ana.25344.

PMID:
    30246887
    [PubMed - as supplied by publisher]
Related citations


White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease.
Araque Caballero MÁ, Suárez-Calvet M, Duering M, Franzmeier N, Benzinger T, Fagan AM, Bateman RJ, Jack CR, Levin J, Dichgans M, Jucker M, Karch C, Masters CL, Morris JC, Weiner M, Rossor M, Fox NC, Lee JH, Salloway S, Danek A, Goate A, Yakushev I, Hassenstab J, Schofield PR, Haass C, Ewers M
Brain. 2018 Oct 1; 141(10)3065-3080. doi: 10.1093/brain/awy229.

PMID:
    30239611
    [PubMed - in process]
Related citations


Rapidly Progressive Dementia in the Outpatient Clinic: More Than Prions.
Day GS, Musiek ES, Morris JC
Alzheimer Dis Assoc Disord. 2018 Sep 14; doi: 10.1097/WAD.0000000000000276.

PMID:
    30222606
    [PubMed - as supplied by publisher]
Related citations


Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease.
McDade E, Wang G, Gordon BA, Hassenstab J, Benzinger TLS, Buckles V, Fagan AM, Holtzman DM, Cairns NJ, Goate AM, Marcus DS, Morris JC, Paumier K, Xiong C, Allegri R, Berman SB, Klunk W, Noble J, Ringman J, Ghetti B, Farlow M, Sperling RA, Chhatwal J, Salloway S, Graff-Radford NR, Schofield PR, Masters C, Rossor MN, Fox NC, Levin J, Jucker M, Bateman RJ, Dominantly Inherited Alzheimer Network.
Neurology. 2018 Oct 2; 91(14)e1295-e1306. doi: 10.1212/WNL.0000000000006277.

PMID:
    30217935
    [PubMed - in process]
Related citations


In Reply-Radiofrequency Ablation Therapy for Large Benign Thyroid Nodules.
Hamidi O, Callstrom MR, Lee RA, Dean D, Castro MR, Morris JC 3rd, Stan MN
Mayo Clin Proc. 2018 Sep; 93(9)1328-1329. doi: 10.1016/j.mayocp.2018.05.006.

PMID:
    30193678
    [PubMed - in process]
Related citations


A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism.
Turner N, Lim XY, Toop HD, Osborne B, Brandon AE, Taylor EN, Fiveash CE, Govindaraju H, Teo JD, McEwen HP, Couttas TA, Butler SM, Das A, Kowalski GM, Bruce CR, Hoehn KL, Fath T, Schmitz-Peiffer C, Cooney GJ, Montgomery MK, Morris JC, Don AS
Nat Commun. 2018 Aug 21; 9(1)3165. doi: 10.1038/s41467-018-05613-7.

PMID:
    30131496
    [PubMed - in process]
Related citations


AHNS Series: Do you know your guidelines? Optimizing outcomes in reoperative parathyroid surgery: Definitive multidisciplinary joint consensus guidelines of the American Head and Neck Society and the British Association of Endocrine and Thyroid Surgeons.
Stack BC Jr, Tolley NS, Bartel TB, Bilezikian JP, Bodenner D, Camacho P, Cox JPDT, Dralle H, Jackson JE, Morris JC 3rd, Orloff LA, Palazzo F, Ridge JA, Scott-Coombes D, Steward DL, Terris DJ, Thompson G, Randolph GW
Head Neck. 2018 Aug; 40(8)1617-1629. doi: 10.1002/hed.25023.

PMID:
    30070413
    [PubMed - in process]
Related citations


Influence of tau PET, amyloid PET, and hippocampal volume on cognition in Alzheimer disease.
Aschenbrenner AJ, Gordon BA, Benzinger TLS, Morris JC, Hassenstab JJ
Neurology. 2018 Aug 28; 91(9)e859-e866. doi: 10.1212/WNL.0000000000006075.

PMID:
    30068637
    [PubMed - in process]
Related citations


Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network.
Karch CM, Hernández D, Wang JC, Marsh J, Hewitt AW, Hsu S, Norton J, Levitch D, Donahue T, Sigurdson W, Ghetti B, Farlow M, Chhatwal J, Berman S, Cruchaga C, Morris JC, Bateman RJ, Dominantly Inherited Alzheimer Network (DIAN)., Pébay A, Goate AM
Alzheimers Res Ther. 2018 Jul 25; 10(1)69. doi: 10.1186/s13195-018-0400-0.

PMID:
    30045758
    [PubMed - in process]
Related citations


Utilizing the Centiloid scale in cross-sectional and longitudinal PiB PET studies.
Su Y, Flores S, Hornbeck RC, Speidel B, Vlassenko AG, Gordon BA, Koeppe RA, Klunk WE, Xiong C, Morris JC, Benzinger TLS
Neuroimage Clin. 2018; 19406-416. doi: 10.1016/j.nicl.2018.04.022.

PMID:
    30035025
    [PubMed - in process]
Related citations


Discovery and validation of autosomal dominant Alzheimer's disease mutations.
Hsu S, Gordon BA, Hornbeck R, Norton JB, Levitch D, Louden A, Ziegemeier E, Laforce R Jr, Chhatwal J, Day GS, McDade E, Morris JC, Fagan AM, Benzinger TLS, Goate AM, Cruchaga C, Bateman RJ, Dominantly Inherited Alzheimer Network (DIAN)., Karch CM
Alzheimers Res Ther. 2018 Jul 18; 10(1)67. doi: 10.1186/s13195-018-0392-9.

PMID:
    30021643
    [PubMed - in process]
Related citations


Extended dosing with CC-486 (oral azacitidine) in patients with myeloid malignancies.
Savona MR, Kolibaba K, Conkling P, Kingsley EC, Becerra C, Morris JC, Rifkin RM, Laille E, Kellerman A, Ukrainskyj SM, Dong Q, Skikne BS
Am J Hematol. 2018 Oct; 93(10)1199-1206. doi: 10.1002/ajh.25216.

PMID:
    30016552
    [PubMed - in process]
Related citations


Effect of BDNFVal66Met on disease markers in dominantly inherited Alzheimer's disease.
Lim YY, Hassenstab J, Goate A, Fagan AM, Benzinger TLS, Cruchaga C, McDade E, Chhatwal J, Levin J, Farlow MR, Graff-Radford NR, Laske C, Masters CL, Salloway S, Schofield P, Morris JC, Maruff P, Bateman RJ, Dominantly Inherited Alzheimer Network.
Ann Neurol. 2018 Sep; 84(3)424-435. doi: 10.1002/ana.25299.

PMID:
    30014553
    [PubMed - in process]
Related citations