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John Carl Morris, MD

Harvey A. and Dorismae Hacker Friedman Professor of Neurology
Professor, Pathology and Immunology
Director, Center for Aging
Director, Memory and Aging Project
Director, Alzheimer's Disease Research Center

Specialty Areas

Neurology - Adult
Memory Disorders and Diagnosis
Alzheimer's Disease
Dementia

Board Certifications

Internal Medicine
Neurology

Hospital Affiliations

Barnes-Jewish Hospital

Referral Information

Referred by Self or Referring Physician

Areas of Clinical Interest

Alzheimer's disease, dementia, geriatric neurology, neurodegenerative diseases, mild cognitive impairment, aging, cognitive function

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Memory Diagnostic Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: (314) 286-1967
Fax: (314) 286-1985
Email: morrisj@neuro.wustl.edu

Education

Education

Fellowship: Neuropharmacology, Washington University School of Medicine, St. Louis, Missouri 1985
Residency: Neuropathology, Cleveland Metropolitan General Hospital, Cleveland, Ohio 1982
Chief Residency: Neurology, Cleveland Metropolitan General Hospital, Cleveland, Ohio 1981
Residency: Internal Medicine, Akron General Medical Center, Akron, Ohio 1979
Medical Degree: University Of Rochester School of Medicine and Dentistry, Rochester, New York 1974
B.A.: Ohio Wesleyan University, Delaware, Ohio 1970

Publication & Research

Publication & Research

Expression of PD-1 and PD-L1 in anaplastic thyroid cancer patients treated with multimodal therapy: results from a retrospective study.
Chintakuntlawar AV, Rumilla KM, Smith CY, Jenkins SM, Foote RL, Kasperbauer JL, Morris JC, Ryder M, Alsidawi S, Hilger C, Bible KC
J Clin Endocrinol Metab. 2017 Mar 7; doi: 10.1210/jc.2016-3756.

PMID:
    28324060
    [PubMed - as supplied by publisher]
Related citations


Mining Outcome-relevant Brain Imaging Genetic Associations via Three-way Sparse Canonical Correlation Analysis in Alzheimer's Disease.
Hao X, Li C, Du L, Yao X, Yan J, Risacher SL, Saykin AJ, Shen L, Zhang D, Alzheimer’s Disease Neuroimaging Initiative.
Sci Rep. 2017 Mar 14; 744272. doi: 10.1038/srep44272.

PMID:
    28291242
    [PubMed - in process]
Related citations


Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.
Deming Y, Li Z, Kapoor M, Harari O, Del-Aguila JL, Black K, Carrell D, Cai Y, Fernandez MV, Budde J, Ma S, Saef B, Howells B, Huang KL, Bertelsen S, Fagan AM, Holtzman DM, Morris JC, Kim S, Saykin AJ, De Jager PL, Albert M, Moghekar A, O'Brien R, Riemenschneider M, Petersen RC, Blennow K, Zetterberg H, Minthon L, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Schellenberg G, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Peskind ER, Li G, Di Narzo AF, Alzheimer’s Disease Neuroimaging Initiative (ADNI)., Alzheimer Disease Genetic Consortium (ADGC)., Kauwe JS, Goate AM, Cruchaga C
Acta Neuropathol. 2017 Feb 28; doi: 10.1007/s00401-017-1685-y.

PMID:
    28247064
    [PubMed - as supplied by publisher]
Related citations


Differentiating cognitive impairment due to corticobasal degeneration and Alzheimer disease.
Day GS, Lim TS, Hassenstab J, Goate AM, Grant EA, Roe CM, Cairns NJ, Morris JC
Neurology. 2017 Feb 24; pii: 10.1212/WNL.0000000000003770. doi: 10.1212/WNL.0000000000003770.

PMID:
    28235814
    [PubMed - as supplied by publisher]
Related citations


The protumorigenic potential of FTY720 by promoting extramedullary hematopoiesis and MDSC accumulation.
Li Y, Zhou T, Wang Y, Ning C, Lv Z, Han G, Morris JC, Taylor EN, Wang R, Xiao H, Hou C, Ma Y, Shen B, Feng J, Guo R, Li Y, Chen G
Oncogene. 2017 Feb 20; doi: 10.1038/onc.2017.2.

PMID:
    28218904
    [PubMed - as supplied by publisher]
Related citations


Pediatric, Adolescent, and Young Adult Thyroid Carcinoma Harbors Frequent and Diverse Targetable Genomic Alterations, Including Kinase Fusions.
Vanden Borre P, Schrock AB, Anderson PM, Morris JC 3rd, Heilmann AM, Holmes O, Wang K, Johnson A, Waguespack SG, Ou SI, Khan S, Fung KM, Stephens PJ, Erlich RL, Miller VA, Ross JS, Ali SM
Oncologist. 2017 Mar; 22(3)255-263. doi: 10.1634/theoncologist.2016-0279.

PMID:
    28209747
    [PubMed - in process]
Related citations


Process Dissociation Analyses of Memory Changes in Healthy Aging, Preclinical, and Very Mild Alzheimer Disease: Evidence for Isolated Recollection Deficits.
Millar PR, Balota DA, Maddox GB, Duchek JM, Aschenbrenner AJ, Fagan AM, Benzinger TL, Morris JC
Neuropsychology. 2017 Feb 16; doi: 10.1037/neu0000352.

PMID:
    28206782
    [PubMed - as supplied by publisher]
Related citations


Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, Foroud TM, Friedland RP, Goate AM, Graff-Radford NR, Hendrie H, Hall KS, Hamilton-Nelson KL, Inzelberg R, Kamboh MI, Kauwe JS, Kukull WA, Kunkle BW, Kuwano R, Larson EB, Logue MW, Manly JJ, Martin ER, Montine TJ, Mukherjee S, Naj A, Reiman EM, Reitz C, Sherva R, St George-Hyslop PH, Thornton T, Younkin SG, Vardarajan BN, Wang LS, Wendlund JR, Winslow AR, Alzheimer's Disease Genetics Consortium., Haines J, Mayeux R, Pericak-Vance MA, Schellenberg G, Lunetta KL, Farrer LA
Alzheimers Dement. 2017 Feb 7; pii: S1552-5260(17)30003-1. doi: 10.1016/j.jalz.2016.12.012.

PMID:
    28183528
    [PubMed - as supplied by publisher]
Related citations


Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.
Batson J, Toop HD, Redondo C, Babaei-Jadidi R, Chaikuad A, Wearmouth SF, Gibbons B, Allen C, Tallant C, Zhang J, Du C, Hancox JC, Hawtrey T, Da Rocha J, Griffith R, Knapp S, Bates DO, Morris JC
ACS Chem Biol. 2017 Mar 17; 12(3)825-832. doi: 10.1021/acschembio.6b01048.

PMID:
    28135068
    [PubMed - in process]
Related citations


Antiparasitic lethality of sulfonamidebenzamides in kinetoplastids.
Hackler A, Patrick SL, Kahney EW, Flaherty DP, Sharlow ER, Morris JC, Golden JE
Bioorg Med Chem Lett. 2017 Feb 15; 27(4)755-758. doi: 10.1016/j.bmcl.2017.01.043.

PMID:
    28119024
    [PubMed - in process]
Related citations


The ATA Guidelines on Management of Thyroid Nodules and Differentiated Thyroid Cancer Task Force Review and Recommendation on the Proposed Renaming of eFVPTC without Invasion to NIFTP.
Haugen BR Md, Sawka AM, Alexander EK, Bible KC, Caturegli P Dr, Doherty G, Mandel SJ, Morris JC 3rd, Nassar A, Pacini F, Schlumberger M, Schuff KG, Sherman SI, Somerset H, Sosa JA, Steward DL, Wartofsky L, Williams MD
Thyroid. 2017 Jan 23; doi: 10.1089/thy.2016.0628.

PMID:
    28114862
    [PubMed - as supplied by publisher]
Related citations


Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease.
Huang M, Yang W, Feng Q, Chen W, Alzheimer’s Disease Neuroimaging Initiative.
Sci Rep. 2017 Jan 12; 739880. doi: 10.1038/srep39880.

PMID:
    28079104
    [PubMed - in process]
Related citations


Multimodal characterization of older APOE2 carriers reveals selective reduction of amyloid load.
Grothe MJ, Villeneuve S, Dyrba M, Bartrés-Faz D, Wirth M, Alzheimer's Disease Neuroimaging Initiative.
Neurology. 2017 Feb 7; 88(6)569-576. doi: 10.1212/WNL.0000000000003585.

PMID:
    28062720
    [PubMed - in process]
Related citations


Safety and pharmacokinetics of cabazitaxel in patients with hepatic impairment: a phase I dose-escalation study.
Sarantopoulos J, Mita AC, He A, Wade JL, Hsueh CT, Morris JC, Lockhart AC, Quinn DI, Hwang J, Mier J, Zhang W, Wack C, Yin J, Clot PF, Rixe O
Cancer Chemother Pharmacol. 2017 Feb; 79(2)339-351. doi: 10.1007/s00280-016-3210-8.

PMID:
    28058445
    [PubMed - in process]
Related citations


Evaluation of substituted ebselen derivatives as potential trypanocidal agents.
Gordhan HM, Patrick SL, Swasy MI, Hackler AL, Anayee M, Golden JE, Morris JC, Whitehead DC
Bioorg Med Chem Lett. 2017 Feb 1; 27(3)537-541. doi: 10.1016/j.bmcl.2016.12.021.

PMID:
    28043795
    [PubMed - in process]
Related citations


Pharmacology of Modulators of Alternative Splicing.
Bates DO, Morris JC, Oltean S, Donaldson LF
Pharmacol Rev. 2017 Jan; 69(1)63-79. doi: 10.1124/pr.115.011239.

PMID:
    28034912
    [PubMed - in process]
Related citations


Association of Functional Impairments and Co-Morbid Conditions with Driving Performance among Cognitively Normal Older Adults.
Carr DB, Barco PP, Babulal GM, Stout SH, Johnson AM, Xiong C, Morris JC, Roe CM
PLoS One. 2016 Dec 22; 11(12)e0167751. doi: 10.1371/journal.pone.0167751.

PMID:
    28005921
    [PubMed - in process]
Related citations


Creating a driving profile for older adults using GPS devices and naturalistic driving methodology.
Babulal GM, Traub CM, Webb M, Stout SH, Addison A, Carr DB, Ott BR, Morris JC, Roe CM
F1000Res. 2016 Sep 26; 52376.

PMID:
    27990264
    [PubMed]
Related citations


Associations Between β-Amyloid Kinetics and the β-Amyloid Diurnal Pattern in the Central Nervous System.
Lucey BP, Mawuenyega KG, Patterson BW, Elbert DL, Ovod V, Kasten T, Morris JC, Bateman RJ
JAMA Neurol. 2017 Feb 1; 74(2)207-215. doi: 10.1001/jamaneurol.2016.4202.

PMID:
    27992627
    [PubMed - in process]
Related citations


Rho GTPases: Anti- or pro-neoplastic targets?
Zandvakili I, Lin Y, Morris JC, Zheng Y
Oncogene. 2016 Dec 19; doi: 10.1038/onc.2016.473.

PMID:
    27991930
    [PubMed - as supplied by publisher]
Related citations