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John Carl Morris, MD

Harvey A. and Dorismae Hacker Friedman Professor of Neurology
Professor, Pathology and Immunology
Director, Center for Aging
Director, Memory and Aging Project
Director, Alzheimer's Disease Research Center

Specialty Areas

Neurology - Adult
Memory Disorders and Diagnosis
Alzheimer's Disease
Dementia

Board Certifications

Internal Medicine
Neurology

Hospital Affiliations

Barnes-Jewish Hospital

Referral Information

Referred by Self or Referring Physician

Areas of Clinical Interest

Alzheimer's disease, dementia, geriatric neurology, neurodegenerative diseases, mild cognitive impairment, aging, cognitive function

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Memory Diagnostic Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: (314) 286-1967
Fax: (314) 286-1985
Email: morrisj@neuro.wustl.edu

Education

Education

Fellowship: Neuropharmacology, Washington University School of Medicine, St. Louis, Missouri 1985
Residency: Neuropathology, Cleveland Metropolitan General Hospital, Cleveland, Ohio 1982
Chief Residency: Neurology, Cleveland Metropolitan General Hospital, Cleveland, Ohio 1981
Residency: Internal Medicine, Akron General Medical Center, Akron, Ohio 1979
Medical Degree: University Of Rochester School of Medicine and Dentistry, Rochester, New York 1974
B.A.: Ohio Wesleyan University, Delaware, Ohio 1970

Publication & Research

Publication & Research

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.
Kun-Rodrigues C, Ross OA, Orme T, Shepherd C, Parkkinen L, Darwent L, Hernandez D, Ansorge O, Clark LN, Honig LS, Marder K, Lemstra A, Scheltens P, van der Flier W, Louwersheimer E, Holstege H, Rogaeva E, St George-Hyslop P, Londos E, Zetterberg H, Barber I, Braae A, Brown K, Morgan K, Maetzler W, Berg D, Troakes C, Al-Sarraj S, Lashley T, Holton J, Compta Y, Van Deerlin V, Trojanowski JQ, Serrano GE, Beach TG, Clarimon J, Lleó A, Morenas-Rodríguez E, Lesage S, Galasko D, Masliah E, Santana I, Diez M, Pastor P, Tienari PJ, Myllykangas L, Oinas M, Revesz T, Lees A, Boeve BF, Petersen RC, Ferman TJ, Escott-Price V, Graff-Radford N, Cairns NJ, Morris JC, Stone DJ, Pickering-Brown S, Mann D, Dickson DW, Halliday GM, Singleton A, Guerreiro R, Bras J
Neurobiol Aging. 2016 Sep 2; pii: S0197-4580(16)30201-9. doi: 10.1016/j.neurobiolaging.2016.08.023.

PMID:
    27666590
    [PubMed - as supplied by publisher]
Related citations


Correction: Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group.
Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, McDade E, Ringman JM, Thompson PM, Saykin AJ, Ghetti B, Sperling RA, Johnson KA, Salloway SP, Schofield PR, Masters CL, Villemagne VL, Fox NC, Förster S, Chen K, Reiman EM, Xiong C, Marcus DS, Weiner MW, Morris JC, Bateman RJ, Benzinger TL, Dominantly Inherited Alzheimer Network
PLoS One. 2016; 11(9)e0163669. doi: 10.1371/journal.pone.0163669.

PMID:
    27649320
    [PubMed - as supplied by publisher]
Related citations


Drug development in Alzheimer's disease: the path to 2025.
Cummings J, Aisen PS, DuBois B, Frölich L, Jack CR Jr, Jones RW, Morris JC, Raskin J, Dowsett SA, Scheltens P
Alzheimers Res Ther. 2016 Sep 20; 839. doi: 10.1186/s13195-016-0207-9.

PMID:
    27646601
    [PubMed - in process]
Related citations


Morphometricity as a measure of the neuroanatomical signature of a trait.
Sabuncu MR, Ge T, Holmes AJ, Smoller JW, Buckner RL, Fischl B, Alzheimer's Disease Neuroimaging Initiative
Proc Natl Acad Sci U S A. 2016 Sep 9; pii: 201604378.

PMID:
    27613854
    [PubMed - as supplied by publisher]
Related citations


Risk of Malignancy in Thyroid Nodules with Non-diagnostic Fine Needle Aspiration: A Retrospective Cohort Study.
Espinosa De Ycaza AE, Lowe KM, Dean DS, Castro MR, Fatourechi V, Ryder M, Morris JC 3rd, Stan MN
Thyroid. 2016 Aug 22;

PMID:
    27549368
    [PubMed - as supplied by publisher]
Related citations


Longitudinal β-Amyloid Deposition and Hippocampal Volume in Preclinical Alzheimer Disease and Suspected Non-Alzheimer Disease Pathophysiology.
Gordon BA, Blazey T, Su Y, Fagan AM, Holtzman DM, Morris JC, Benzinger TL
JAMA Neurol. 2016 Aug 22; doi: 10.1001/jamaneurol.2016.2642.

PMID:
    27548756
    [PubMed - as supplied by publisher]
Related citations


Ramifications of New Terminology for Encapsulated Follicular Variant of Papillary Thyroid Carcinoma.
Brito JP, Ospina NM, Morris JC
JAMA Oncol. 2016 Aug 1; 2(8)1097. doi: 10.1001/jamaoncol.2016.2208.

PMID:
    27533607
    [PubMed - in process]
Related citations


BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease.
Lim YY, Hassenstab J, Cruchaga C, Goate A, Fagan AM, Benzinger TL, Maruff P, Snyder PJ, Masters CL, Allegri R, Chhatwal J, Farlow MR, Graff-Radford NR, Laske C, Levin J, McDade E, Ringman JM, Rossor M, Salloway S, Schofield PR, Holtzman DM, Morris JC, Bateman RJ, Dominantly Inherited Alzheimer Network
Brain. 2016 Oct; 139(Pt 10)2766-2777.

PMID:
    27521573
    [PubMed - as supplied by publisher]
Related citations


Physical exam in asymptomatic people drivers the detection of thyroid nodules undergoing ultrasound guided fine needle aspiration biopsy.
Singh Ospina N, Maraka S, Espinosa De Ycaza AE, Ahn HS, Castro MR, Morris JC, Montori VM, Brito JP
Endocrine. 2016 Aug 10;

PMID:
    27510173
    [PubMed - as supplied by publisher]
Related citations


Phase II study of alemtuzumab (CAMPATH-1®) in patients with HTLV-1-associated adult T-cell leukemia/lymphoma.
Sharma K, Janik J, O'Mahony D, Stewart D, Pittaluga S, Stetler-Stevenson M, Jaffe ES, Raffeld M, Fleisher T, Lee C, Steinberg SM, Waldmann TA, Morris JC
Clin Cancer Res. 2016 Aug 2; pii: clincanres.1022.2016.

PMID:
    27486175
    [PubMed - as supplied by publisher]
Related citations


Identification of Novel Plasmodium falciparum Hexokinase Inhibitors with Antiparasitic Activity.
Davis MI, Patrick SL, Blanding WM, Dwivedi V, Suryadi J, Golden JE, Coussens NP, Lee OW, Shen M, Boxer MB, Hall MD, Sharlow ER, Drew ME, Morris JC
Antimicrob Agents Chemother. 2016 Oct; 60(10)6023-33. doi: 10.1128/AAC.00914-16.

PMID:
    27458230
    [PubMed - in process]
Related citations


Edgeworth David McIntyre, AM, MB BS, FRCSEd, FRCS, FRACS.
Morris JC
Med J Aust. 2016 Jul 18; 205(2)62.

PMID:
    27456443
    [PubMed - in process]
Related citations


Evaluation of Tau Imaging in Staging Alzheimer Disease and Revealing Interactions Between β-Amyloid and Tauopathy.
Wang L, Benzinger TL, Su Y, Christensen J, Friedrichsen K, Aldea P, McConathy J, Cairns NJ, Fagan AM, Morris JC, Ances BM
JAMA Neurol. 2016 Sep 1; 73(9)1070-7. doi: 10.1001/jamaneurol.2016.2078.

PMID:
    27454922
    [PubMed - in process]
Related citations


Phenotypic Similarities Between Late-Onset Autosomal Dominant and Sporadic Alzheimer Disease: A Single-Family Case-Control Study.
Day GS, Musiek ES, Roe CM, Norton J, Goate AM, Cruchaga C, Cairns NJ, Morris JC
JAMA Neurol. 2016 Sep 1; 73(9)1125-32. doi: 10.1001/jamaneurol.2016.1236.

PMID:
    27454811
    [PubMed - in process]
Related citations


Mood Changes in Cognitively Normal Older Adults are Linked to Alzheimer Disease Biomarker Levels.
Babulal GM, Ghoshal N, Head D, Vernon EK, Holtzman DM, Benzinger TL, Fagan AM, Morris JC, Roe CM
Am J Geriatr Psychiatry. 2016 Apr 19; pii: S1064-7481(16)30082-3. doi: 10.1016/j.jagp.2016.04.004.

PMID:
    27426238
    [PubMed - as supplied by publisher]
Related citations


Imaging and cerebrospinal fluid biomarkers in early preclinical alzheimer disease.
Vlassenko AG, McCue L, Jasielec MS, Su Y, Gordon BA, Xiong C, Holtzman DM, Benzinger TL, Morris JC, Fagan AM
Ann Neurol. 2016 Sep; 80(3)379-87. doi: 10.1002/ana.24719.

PMID:
    27398953
    [PubMed - in process]
Related citations


Polygenic risk of Alzheimer disease is associated with early- and late-life processes.
Mormino EC, Sperling RA, Holmes AJ, Buckner RL, De Jager PL, Smoller JW, Sabuncu MR, Alzheimer's Disease Neuroimaging Initiative
Neurology. 2016 Aug 2; 87(5)481-8. doi: 10.1212/WNL.0000000000002922.

PMID:
    27385740
    [PubMed - in process]
Related citations


Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer's disease.
Muenchhoff J, Poljak A, Thalamuthu A, Gupta VB, Chatterjee P, Raftery M, Masters CL, Morris JC, Bateman RJ, Fagan AM, Martins RN, Sachdev PS
Sci Rep. 2016 Jul 6; 629078. doi: 10.1038/srep29078.

PMID:
    27381087
    [PubMed - in process]
Related citations


NIA-AA staging of preclinical Alzheimer disease: discordance and concordance of CSF and imaging biomarkers.
Vos SJ, Gordon BA, Su Y, Visser PJ, Holtzman DM, Morris JC, Fagan AM, Benzinger TL
Neurobiol Aging. 2016 Aug; 441-8. doi: 10.1016/j.neurobiolaging.2016.03.025.

PMID:
    27318129
    [PubMed - in process]
Related citations


The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging.
Gordon BA, Friedrichsen K, Brier M, Blazey T, Su Y, Christensen J, Aldea P, McConathy J, Holtzman DM, Cairns NJ, Morris JC, Fagan AM, Ances BM, Benzinger TL
Brain. 2016 Aug; 139(Pt 8)2249-60. doi: 10.1093/brain/aww139.

PMID:
    27286736
    [PubMed - in process]
Related citations