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Faculty Physicians

Joan L. Rosenbaum, MD

Professor, Pediatrics
Division of Newborn Medicine

Specialty Areas

Newborn Medicine - Neonatology
Neonatal/Perinatal Medicine

Board Certifications

Neonatal-Perinatal Medicine
Pediatrics

Hospital Affiliations

Barnes-Jewish Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Pediatric medicine, pulmonary hypertension, cerebral glucose transport, metabolism, neonatal disease. low birthweight, prematurity

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: Neonatal Intensive Care Unit (NICU), 5th Floor
Office Phone: 314-454-6148
Fax: 314-454-4633

Education

Education

Fellowship: Neonatal-Perinatal Medicine, Washington University School of Medicine, St. Louis, MO 1989
Residency: St. Louis Children's Hospital, St. Louis, MO 1986
Medical School: University Of Texas Medical School, Houston, TX 1983
M.A.: University of California, Los Angeles, CA 1980
B.A.: Rice University, Houston, TX 1978

Publication & Research

Publication & Research

Ciliary ectosomes: transmissions from the cell's antenna.
Wood CR, Rosenbaum JL
Trends Cell Biol. 2015 May; 25(5)276-85. doi: 10.1016/j.tcb.2014.12.008.

PMID:
    25618328
    [PubMed - indexed for MEDLINE]
Related citations


Proteomic analysis of isolated ciliary transition zones reveals the presence of ESCRT proteins.
Diener DR, Lupetti P, Rosenbaum JL
Curr Biol. 2015 Feb 2; 25(3)379-84. doi: 10.1016/j.cub.2014.11.066.

PMID:
    25578910
    [PubMed - indexed for MEDLINE]
Related citations


Impact of a Neonatal-Bereavement-Support DVD on Parental Grief: A Randomized Controlled Trial.
Rosenbaum JL, Smith JR, Yan Y, Abram N, Jeffe DB
Death Stud. 2015 Jan-Jun; 39(1-5)191-200. doi: 10.1080/07481187.2014.946628.

PMID:
    25530502
    [PubMed - indexed for MEDLINE]
Related citations


Proteins of the ciliary axoneme are found on cytoplasmic membrane vesicles during growth of cilia.
Wood CR, Rosenbaum JL
Curr Biol. 2014 May 19; 24(10)1114-20. doi: 10.1016/j.cub.2014.03.047.

PMID:
    24814148
    [PubMed - indexed for MEDLINE]
Related citations


Results of the two incidence screenings in the National Lung Screening Trial.
Aberle DR, DeMello S, Berg CD, Black WC, Brewer B, Church TR, Clingan KL, Duan F, Fagerstrom RM, Gareen IF, Gatsonis CA, Gierada DS, Jain A, Jones GC, Mahon I, Marcus PM, Rathmell JM, Sicks J, National Lung Screening Trial Research Team
N Engl J Med. 2013 Sep 5; 369(10)920-31. doi: 10.1056/NEJMoa1208962.

PMID:
    24004119
    [PubMed - indexed for MEDLINE]
Related citations


The cilium secretes bioactive ectosomes.
Wood CR, Huang K, Diener DR, Rosenbaum JL
Curr Biol. 2013 May 20; 23(10)906-11. doi: 10.1016/j.cub.2013.04.019.

PMID:
    23623554
    [PubMed - indexed for MEDLINE]
Related citations


The versatile molecular complex component LC8 promotes several distinct steps of flagellar assembly.
Gupta A, Diener DR, Sivadas P, Rosenbaum JL, Yang P
J Cell Biol. 2012 Jul 9; 198(1)115-26. doi: 10.1083/jcb.201111041.

PMID:
    22753897
    [PubMed - indexed for MEDLINE]
Related citations


Target-of-rapamycin complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation.
Yuan S, Li J, Diener DR, Choma MA, Rosenbaum JL, Sun Z
Proc Natl Acad Sci U S A. 2012 Feb 7; 109(6)2021-6. doi: 10.1073/pnas.1112834109.

PMID:
    22308353
    [PubMed - indexed for MEDLINE]
Related citations


Reduced lung-cancer mortality with low-dose computed tomographic screening.
National Lung Screening Trial Research Team, Aberle DR, Adams AM, Berg CD, Black WC, Clapp JD, Fagerstrom RM, Gareen IF, Gatsonis C, Marcus PM, Sicks JD
N Engl J Med. 2011 Aug 4; 365(5)395-409. doi: 10.1056/NEJMoa1102873.

PMID:
    21714641
    [PubMed - indexed for MEDLINE]
Related citations


Sequential assembly of flagellar radial spokes.
Diener DR, Yang P, Geimer S, Cole DG, Sale WS, Rosenbaum JL
Cytoskeleton (Hoboken). 2011 Jul; 68(7)389-400. doi: 10.1002/cm.20520.

PMID:
    21692193
    [PubMed - indexed for MEDLINE]
Related citations


Subunit interactions within the Chlamydomonas flagellar spokehead.
Kohno T, Wakabayashi K, Diener DR, Rosenbaum JL, Kamiya R
Cytoskeleton (Hoboken). 2011 Apr; 68(4)237-46. doi: 10.1002/cm.20507.

PMID:
    21391306
    [PubMed - indexed for MEDLINE]
Related citations


Neonatal end-of-life spiritual support care.
Rosenbaum JL, Smith JR, Zollfrank R
J Perinat Neonatal Nurs. 2011 Jan-Mar; 25(1)61-9; quiz 70-1. doi: 10.1097/JPN.0b013e318209e1d2.

PMID:
    21311271
    [PubMed - indexed for MEDLINE]
Related citations


Nickel and low CO₂-controlled motility in Chlamydomonas through complementation of a paralyzed flagella mutant with chemically regulated promoters.
Ferrante P, Diener DR, Rosenbaum JL, Giuliano G
BMC Plant Biol. 2011 Jan 25; 1122. doi: 10.1186/1471-2229-11-22.

PMID:
    21266063
    [PubMed - indexed for MEDLINE]
Related citations


The National Lung Screening Trial: overview and study design.
National Lung Screening Trial Research Team, Aberle DR, Berg CD, Black WC, Church TR, Fagerstrom RM, Galen B, Gareen IF, Gatsonis C, Goldin J, Gohagan JK, Hillman B, Jaffe C, Kramer BS, Lynch D, Marcus PM, Schnall M, Sullivan DC, Sullivan D, Zylak CJ
Radiology. 2011 Jan; 258(1)243-53. doi: 10.1148/radiol.10091808.

PMID:
    21045183
    [PubMed - indexed for MEDLINE]
Related citations


CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content.
Craige B, Tsao CC, Diener DR, Hou Y, Lechtreck KF, Rosenbaum JL, Witman GB
J Cell Biol. 2010 Sep 6; 190(5)927-40. doi: 10.1083/jcb.201006105.

PMID:
    20819941
    [PubMed - indexed for MEDLINE]
Related citations


Centrioles are freed from cilia by severing prior to mitosis.
Parker JD, Hilton LK, Diener DR, Rasi MQ, Mahjoub MR, Rosenbaum JL, Quarmby LM
Cytoskeleton (Hoboken). 2010 Jul; 67(7)425-30. doi: 10.1002/cm.20454.

PMID:
    20506243
    [PubMed - indexed for MEDLINE]
Related citations


Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse.
Finetti F, Paccani SR, Riparbelli MG, Giacomello E, Perinetti G, Pazour GJ, Rosenbaum JL, Baldari CT
Nat Cell Biol. 2009 Nov; 11(11)1332-9. doi: 10.1038/ncb1977.

PMID:
    19855387
    [PubMed - indexed for MEDLINE]
Related citations


Electron-tomographic analysis of intraflagellar transport particle trains in situ.
Pigino G, Geimer S, Lanzavecchia S, Paccagnini E, Cantele F, Diener DR, Rosenbaum JL, Lupetti P
J Cell Biol. 2009 Oct 5; 187(1)135-48. doi: 10.1083/jcb.200905103.

PMID:
    19805633
    [PubMed - indexed for MEDLINE]
Related citations


The ubiquitin conjugation system is involved in the disassembly of cilia and flagella.
Huang K, Diener DR, Rosenbaum JL
J Cell Biol. 2009 Aug 24; 186(4)601-13. doi: 10.1083/jcb.200903066.

PMID:
    19704024
    [PubMed - indexed for MEDLINE]
Related citations


Intraflagellar transport (IFT) role in ciliary assembly, resorption and signalling.
Pedersen LB, Rosenbaum JL
Curr Top Dev Biol. 2008; 8523-61. doi: 10.1016/S0070-2153(08)00802-8.

PMID:
    19147001
    [PubMed - indexed for MEDLINE]
Related citations