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Joan L. Luby, MD

Samuel and Mae S. Ludwig Professor of Child Psychiatry
Director, Early Emotional Development Program

Specialty Areas

Child and Adolescent Psychiatry
Infant/Preschool Mental Disorders
Forensic Psychiatry

Board Certifications

Child Psychiatry

Hospital Affiliations

Barnes-Jewish Hospital
Missouri Baptist Medical Center
St. Louis Children's Hospital

Areas of Clinical Interest

Mood disorders in preschool children: diagnosis and treatment, developmental psychopathology, mental disorders in preschool children, Dyadic Play Therapy for preschool mood disorders, and preschool psychiatry.

  • Education
  • Publication & Research



Fellowship: Child Psychiatry, Stanford University School of Medicine, Stanford, California 1990
Residency: Psychiatry, Stanford University School of Medicine, Stanford, California 1988
Medical Degree: Wayne State University School of Medicine, Detroit, Michigan 1985
A.B.: Brown University, Providence, Rhode Island 1981

Publication & Research

Publication & Research

Luby JL, Barch D, Whalen D, Tillman R, Belden A, (2017 Dec). Association Between Early Life Adversity and Risk for Poor Emotional and Physical Health in Adolescence: A Putative Mechanistic Neurodevelopmental Pathway. JAMA Pediatr. 171(12): 1168-1175.  

Gaffrey MS, Barch DM, Bogdan R, Farris K, Petersen SE, Luby JL, (2018 Jan). Amygdala Reward Reactivity Mediates the Association Between Preschool Stress Response and Depression Severity. Biol. Psychiatry. 83(2): 128-136.  

Luby JL, Agrawal A, Belden A, Whalen D, Tillman R, Barch DM, (2018 Mar). Developmental Trajectories of the Orbitofrontal Cortex and Anhedonia in Middle Childhood and Risk for Substance Use in Adolescence in a Longitudinal Sample of Depressed and Healthy Preschoolers. Am J Psychiatry. appiajp201817070777.  

Barch DM, Belden AC, Tillman R, Whalen D, Luby JL, (2018 Mar). Early Childhood Adverse Experiences, Inferior Frontal Gyrus Connectivity, and the Trajectory of Externalizing Psychopathology. J Am Acad Child Adolesc Psychiatry. 57(3): 183-190.  

Lopez KC, Luby JL, Belden AC, Barch DM, (2018 Apr). Emotion dysregulation and functional connectivity in children with and without a history of major depressive disorder. Cogn Affect Behav Neurosci. 18(2): 232-248.  

Pagliaccio D, Pine DS, Barch DM, Luby JL, Leibenluft E, (2018 May). Irritability Trajectories, Cortical Thickness, and Clinical Outcomes in a Sample Enriched for Preschool Depression. J Am Acad Child Adolesc Psychiatry. 57(5): 336-342.e6.  

Areas of Research Interest

Studies of early onset depression, validators, clinical characteristics, biological markers and alterations in brain structure and function related to early onset depression; Psychotherapeutic treatments for early onset depression focusing on emotion development; Studies of early experience and brain development; Studies of alterations in emotion development in early onset mood disorders; Novel treatments for early onset depression focused on attention bias; and sensitive periods in emotion development.