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Jennifer Strahle, MD

Assistant Professor, Neurosurgery
Assistant Professor, Orthopedic Surgery
Assistant Professor, Pediatrics

Specialty Areas

Pediatric Neurosurgery
Spine Surgery - Neurosurgery

Hospital Affiliations

St. Louis Children's Hospital
Barnes-Jewish Hospital

Areas of Clinical Interest

Pediatric neurosurgery, spinal deformity (scoliosis, kyphosis, spondylolisthesis), pediatric brain tumors, craniocervical junction disorders, spina bifida, Chiari malformations, neuro-endoscopy, pediatric spine trauma, syringomyelia, hydrocephalus, Moyamoya   

  • Location(s)
  • Education
  • Publication & Research

Location(s)

Location(s)

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: 4S20
Office Phone: 314-454-2810

Education

Education

Fellowship: Pediatric Neurosurgery, Washington University School of Medicine, St. Louis, Missouri 2016
Residency: Neurosurgery, University of Michigan, Ann Arbor, Michigan 2015
Medical Degree: University of Minnesota Medical School, Minneapolis, Minnesota 2008
Bachelor's Degree: Bates College, Lewiston, Maine 2002

Publication & Research

Publication & Research

Factors associated with syrinx size in pediatric patients treated for Chiari malformation type I and syringomyelia: a study from the Park-Reeves Syringomyelia Research Consortium.
Hale AT, Adelson PD, Albert GW, Aldana PR, Alden TD, Anderson RCE, Bauer DF, Bonfield CM, Brockmeyer DL, Chern JJ, Couture DE, Daniels DJ, Durham SR, Ellenbogen RG, Eskandari R, George TM, Grant GA, Graupman PC, Greene S, Greenfield JP, Gross NL, Guillaume DJ, Heuer GG, Iantosca M, Iskandar BJ, Jackson EM, Johnston JM, Keating RF, Leonard JR, Maher CO, Mangano FT, McComb JG, Meehan T, Menezes AH, O'Neill B, Olavarria G, Park TS, Ragheb J, Selden NR, Shah MN, Smyth MD, Stone SSD, Strahle JM, Wait SD, Wellons JC, Whitehead WE, Shannon CN, Limbrick DD, Park-Reeves Syringomyelia Research Consortium Investigators.
J Neurosurg Pediatr. 2020 Mar 6; 1-11. doi: 10.3171/2020.1.PEDS19493.

PMID:
    32114543
    [PubMed - as supplied by publisher]
Related citations


Prevalence and Impact of Underlying Diagnosis and Comorbidities on Chiari 1 Malformation.
Sadler B, Kuensting T, Strahle J, Park TS, Smyth M, Limbrick DD, Dobbs MB, Haller G, Gurnett CA
Pediatr Neurol. 2020 Jan 21; pii: S0887-8994(19)30995-6. doi: 10.1016/j.pediatrneurol.2019.12.005.

PMID:
    32113729
    [PubMed - as supplied by publisher]
Related citations


Cerebrovascular Complications of Pediatric Blunt Trauma.
Galardi MM, Strahle JM, Skidmore A, Kansagra AP, Guilliams KP
Pediatr Neurol. 2020 Jan 11; pii: S0887-8994(19)30999-3. doi: 10.1016/j.pediatrneurol.2019.12.009.

PMID:
    32111560
    [PubMed - as supplied by publisher]
Related citations


Syringomyelia in children with closed spinal dysraphism: long-term outcomes after surgical intervention.
Bruzek AK, Starr J, Garton HJL, Muraszko KM, Maher CO, Strahle JM
J Neurosurg Pediatr. 2019 Dec 13; 1-7. doi: 10.3171/2019.9.PEDS1944.

PMID:
    31835253
    [PubMed - as supplied by publisher]
Related citations


Radiological and clinical predictors of scoliosis in patients with Chiari malformation type I and spinal cord syrinx from the Park-Reeves Syringomyelia Research Consortium.
Strahle JM, Taiwo R, Averill C, Torner J, Shannon CN, Bonfield CM, Tuite GF, Bethel-Anderson T, Rutlin J, Brockmeyer DL, Wellons JC, Leonard JR, Mangano FT, Johnston JM, Shah MN, Iskandar BJ, Tyler-Kabara EC, Daniels DJ, Jackson EM, Grant GA, Couture DE, Adelson PD, Alden TD, Aldana PR, Anderson RCE, Selden NR, Baird LC, Bierbrauer K, Chern JJ, Whitehead WE, Ellenbogen RG, Fuchs HE, Guillaume DJ, Hankinson TC, Iantosca MR, Oakes WJ, Keating RF, Khan NR, Muhlbauer MS, McComb JG, Menezes AH, Ragheb J, Smith JL, Maher CO, Greene S, Kelly M, O'Neill BR, Krieger MD, Tamber M, Durham SR, Olavarria G, Stone SSD, Kaufman BA, Heuer GG, Bauer DF, Albert G, Greenfield JP, Wait SD, Van Poppel MD, Eskandari R, Mapstone T, Shimony JS, Dacey RG, Smyth MD, Park TS, Limbrick DD
J Neurosurg Pediatr. 2019 Aug 16; 1-8. doi: 10.3171/2019.5.PEDS18527.

PMID:
    31419800
    [PubMed - as supplied by publisher]
Related citations


Feasibility of fast brain diffusion MRI to quantify white matter injury in pediatric hydrocephalus.
Isaacs AM, Shimony JS, Morales DM, Castaneyra-Ruiz L, Hartman A, Cook M, Smyser CD, Strahle J, Smyth MD, Yan Y, McAllister JP, McKinstry RC, Limbrick DD
J Neurosurg Pediatr. 2019 Jul 19; 1-8. doi: 10.3171/2019.5.PEDS18596.

PMID:
    31323624
    [PubMed - as supplied by publisher]
Related citations


Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma.
Henrik Heiland D, Ravi VM, Behringer SP, Frenking JH, Wurm J, Joseph K, Garrelfs NWC, Strähle J, Heynckes S, Grauvogel J, Franco P, Mader I, Schneider M, Potthoff AL, Delev D, Hofmann UG, Fung C, Beck J, Sankowski R, Prinz M, Schnell O
Nat Commun. 2019 Jun 11; 10(1)2541. doi: 10.1038/s41467-019-10493-6.

PMID:
    31186414
    [PubMed - indexed for MEDLINE]
Related citations


Impaired hippocampal development and outcomes in very preterm infants with perinatal brain injury.
Strahle JM, Triplett RL, Alexopoulos D, Smyser TA, Rogers CE, Limbrick DD Jr, Smyser CD
Neuroimage Clin. 2019; 22101787. doi: 10.1016/j.nicl.2019.101787.

PMID:
    30991622
    [PubMed - indexed for MEDLINE]
Related citations


Evaluation of pediatric glioma outcomes using intraoperative MRI: a multicenter cohort study.
Karsy M, Akbari SH, Limbrick D, Leuthardt EC, Evans J, Smyth MD, Strahle J, Leonard J, Cheshier S, Brockmeyer DL, Bollo RJ, Kestle JR, Honeycutt J, Donahue DJ, Roberts RA, Hansen DR, Riva-Cambrin J, Sutherland G, Gallagher C, Hader W, Starreveld Y, Hamilton M, Duhaime AC, Jensen RL, Chicoine MR
J Neurooncol. 2019 Jun; 143(2)271-280. doi: 10.1007/s11060-019-03154-7.

PMID:
    30977059
    [PubMed - indexed for MEDLINE]
Related citations


Blood Exposure Causes Ventricular Zone Disruption and Glial Activation In Vitro.
Castaneyra-Ruiz L, Morales DM, McAllister JP, Brody SL, Isaacs AM, Strahle JM, Dahiya SM, Limbrick DD
J Neuropathol Exp Neurol. 2018 Sep 1; 77(9)803-813. doi: 10.1093/jnen/nly058.

PMID:
    30032242
    [PubMed - indexed for MEDLINE]
Related citations


Predictors of mortality for preterm infants with intraventricular hemorrhage: a population-based study.
Han RH, McKinnon A, CreveCoeur TS, Baksh BS, Mathur AM, Smyser CD, Strahle JM, Olsen MA, Limbrick DD Jr
Childs Nerv Syst. 2018 Nov; 34(11)2203-2213. doi: 10.1007/s00381-018-3897-4.

PMID:
    29987373
    [PubMed - indexed for MEDLINE]
Related citations


De Novo Mutation in Genes Regulating Neural Stem Cell Fate in Human Congenital Hydrocephalus.
Furey CG, Choi J, Jin SC, Zeng X, Timberlake AT, Nelson-Williams C, Mansuri MS, Lu Q, Duran D, Panchagnula S, Allocco A, Karimy JK, Khanna A, Gaillard JR, DeSpenza T, Antwi P, Loring E, Butler WE, Smith ER, Warf BC, Strahle JM, Limbrick DD, Storm PB, Heuer G, Jackson EM, Iskandar BJ, Johnston JM, Tikhonova I, Castaldi C, López-Giráldez F, Bjornson RD, Knight JR, Bilguvar K, Mane S, Alper SL, Haider S, Guclu B, Bayri Y, Sahin Y, Apuzzo MLJ, Duncan CC, DiLuna ML, Günel M, Lifton RP, Kahle KT
Neuron. 2018 Jul 25; 99(2)302-314.e4. doi: 10.1016/j.neuron.2018.06.019.

PMID:
    29983323
    [PubMed - indexed for MEDLINE]
Related citations


Focal traumatic rupture of a dermoid cyst in a pediatric patient: case report and literature review.
Akbari SHA, Somasundaram A, Ferguson CJ, Roland JL, Smyth MD, Strahle JM
Childs Nerv Syst. 2018 Dec; 34(12)2485-2490. doi: 10.1007/s00381-018-3879-6.

PMID:
    29961083
    [PubMed - indexed for MEDLINE]
Related citations


Bartonella henselae infection presenting as cervical spine osteomyelitis: case report.
Akbari SHA, Averill CE, Roland JL, Orscheln R, Strahle J
J Neurosurg Pediatr. 2018 Aug; 22(2)189-194. doi: 10.3171/2018.2.PEDS17600.

PMID:
    29799351
    [PubMed - indexed for MEDLINE]
Related citations


Opportunities in posthemorrhagic hydrocephalus research: outcomes of the Hydrocephalus Association Posthemorrhagic Hydrocephalus Workshop.
Koschnitzky JE, Keep RF, Limbrick DD Jr, McAllister JP 2nd, Morris JA, Strahle J, Yung YC
Fluids Barriers CNS. 2018 Mar 27; 15(1)11. doi: 10.1186/s12987-018-0096-3.

PMID:
    29587767
    [PubMed - indexed for MEDLINE]
Related citations


Morphometric and volumetric comparison of 102 children with symptomatic and asymptomatic Chiari malformation Type I.
Khalsa SSS, Geh N, Martin BA, Allen PA, Strahle J, Loth F, Habtzghi D, Urbizu Serrano A, McQuaide D, Garton HJL, Muraszko KM, Maher CO
J Neurosurg Pediatr. 2018 Jan; 21(1)65-71. doi: 10.3171/2017.8.PEDS17345.

PMID:
    29125445
    [PubMed - indexed for MEDLINE]
Related citations


The Role of Preoperative Imaging in the Management of Nonsyndromic Lambdoid Craniosynostosis.
Ranganathan K, Rampazzo A, Hashmi A, Muraszko K, Strahle J, Vercler CJ, Buchman SR
J Craniofac Surg. 2018 Jan; 29(1)36-39. doi: 10.1097/SCS.0000000000004026.

PMID:
    29040146
    [PubMed - indexed for MEDLINE]
Related citations


Time-to-event analysis of surgically treated posthemorrhagic hydrocephalus in preterm infants: a single-institution retrospective study.
Han RH, Berger D, Gabir M, Baksh BS, Morales DM, Mathur AM, Smyser CD, Strahle JM, Limbrick DD Jr
Childs Nerv Syst. 2017 Nov; 33(11)1917-1926. doi: 10.1007/s00381-017-3588-6.

PMID:
    28884229
    [PubMed - indexed for MEDLINE]
Related citations


Cerebrospinal fluid biomarkers of infantile congenital hydrocephalus.
Limbrick DD Jr, Baksh B, Morgan CD, Habiyaremye G, McAllister JP 2nd, Inder TE, Mercer D, Holtzman DM, Strahle J, Wallendorf MJ, Morales DM
PLoS One. 2017; 12(2)e0172353. doi: 10.1371/journal.pone.0172353.

PMID:
    28212403
    [PubMed - indexed for MEDLINE]
Related citations


Letter to the Editor: Are arachnoid cysts and Chiari malformation Type I more common in those with postconcussion syndrome?
Strahle J, Maher CO
J Neurosurg. 2016 Nov; 125(5)1320-1322.

PMID:
    27611207
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Mechanisms of hydrocephalus and brain injury after neonatal intraventricular hemorrhage; Chiari, syrinx and scoliosis in the pediatric population