Patient Portal

Jennifer A. Wambach, MD, MS

Assistant Professor, Pediatrics
Division of Newborn Medicine

Specialty Areas

Neonatal/Perinatal Medicine

Board Certifications

Pediatrics
Neonatal / Perinatal Medicine

Hospital Affiliations

St. Louis Children's Hospital

Areas of Clinical Interest

newborn medicine

  • Location(s)
  • Education
  • Publication & Research

Location(s)

Location(s)

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Office Phone: 314-454-6148
Fax: 314-454-4633

Education

Education

BS: Pediatrics, Vanderbilt University, Nashville, TN 1997
Medical Degree: Vanderbilt University School of Medicine, Nashville TN 2001
Residency: Pediatrics, Northwestern University School of Medicine, Chicago, IL 2004
MS: Washington University School of Medicine, St Louis, MO 2010
Chief Resident: Pediatrics, Northwestern University School of Medicine, Chicago, IL 2005
Fellowship: Newborn Medicine, Washington University School of Medicine, St. Louis, MO 2008

Publication & Research

Publication & Research

Functional Genomics of ATP-Binding Cassette Transporter A3 (ABCA3) Variants.
Wambach JA, Yang P, Wegner DJ, Heins HB, Luke C, Li F, White FV, Cole FS
Am J Respir Cell Mol Biol. 2020 Jul 21; doi: 10.1165/rcmb.2020-0034MA.

PMID:
    32692933
    [PubMed - as supplied by publisher]
Related citations


Childhood rare lung disease in the 21st century: "-omics" technology advances accelerating discovery.
Vece TJ, Wambach JA, Hagood JS
Pediatr Pulmonol. 2020 Jul; 55(7)1828-1837. doi: 10.1002/ppul.24809.

PMID:
    32533908
    [PubMed - in process]
Related citations


Functional characterization of four ATP-binding cassette transporter A3 gene (ABCA3) variants.
Hu JY, Yang P, Wegner DJ, Heins HB, Luke CJ, Li F, White FV, Silverman GA, Sessions Cole F, Wambach JA
Hum Mutat. 2020 Jul; 41(7)1298-1307. doi: 10.1002/humu.24014.

PMID:
    32196812
    [PubMed - in process]
Related citations


Phenotypic expansion of KMT2D-related disorder: Beyond Kabuki syndrome.
Baldridge D, Spillmann RC, Wegner DJ, Wambach JA, White FV, Sisco K, Toler TL, Dickson PI, Cole FS, Shashi V, Grange DK
Am J Med Genet A. 2020 May; 182(5)1053-1065. doi: 10.1002/ajmg.a.61518.

PMID:
    32083401
    [PubMed - in process]
Related citations


A Step toward Treating a Lethal Neonatal Lung Disease. STAT3 and Alveolar Capillary Dysplasia.
Wambach JA, Nogee LM
Am J Respir Crit Care Med. 2019 Oct 15; 200(8)961-962. doi: 10.1164/rccm.201906-1102ED.

PMID:
    31343895
    [PubMed - indexed for MEDLINE]
Related citations


Novel parent-of-origin-specific differentially methylated loci on chromosome 16.
Schulze KV, Szafranski P, Lesmana H, Hopkin RJ, Hamvas A, Wambach JA, Shinawi M, Zapata G, Carvalho CMB, Liu Q, Karolak JA, Lupski JR, Hanchard NA, Stankiewicz P
Clin Epigenetics. 2019 Apr 8; 11(1)60. doi: 10.1186/s13148-019-0655-8.

PMID:
    30961659
    [PubMed - indexed for MEDLINE]
Related citations


Phenotype and response to growth hormone therapy in siblings with B4GALT7 deficiency.
Sandler-Wilson C, Wambach JA, Marshall BA, Wegner DJ, McAlister W, Cole FS, Shinawi M
Bone. 2019 Jul; 12414-21. doi: 10.1016/j.bone.2019.03.029.

PMID:
    30914273
    [PubMed - indexed for MEDLINE]
Related citations


CemOrange2 fusions facilitate multifluorophore subcellular imaging in C. elegans.
Thomas BJ, Wight IE, Chou WYY, Moreno M, Dawson Z, Homayouni A, Huang H, Kim H, Jia H, Buland JR, Wambach JA, Cole FS, Pak SC, Silverman GA, Luke CJ
PLoS One. 2019; 14(3)e0214257. doi: 10.1371/journal.pone.0214257.

PMID:
    30913273
    [PubMed - indexed for MEDLINE]
Related citations


Bi-allelic POLR3A Loss-of-Function Variants Cause Autosomal-Recessive Wiedemann-Rautenstrauch Syndrome.
Wambach JA, Wegner DJ, Patni N, Kircher M, Willing MC, Baldridge D, Xing C, Agarwal AK, Vergano SAS, Patel C, Grange DK, Kenney A, Najaf T, Nickerson DA, Bamshad MJ, Cole FS, Garg A
Am J Hum Genet. 2018 Dec 6; 103(6)968-975. doi: 10.1016/j.ajhg.2018.10.010.

PMID:
    30414627
    [PubMed - indexed for MEDLINE]
Related citations


Functional characterization of biallelic RTTN variants identified in an infant with microcephaly, simplified gyral pattern, pontocerebellar hypoplasia, and seizures.
Wambach JA, Wegner DJ, Yang P, Shinawi M, Baldridge D, Betleja E, Shimony JS, Spencer D, Hackett BP, Andrews MV, Ferkol T, Dutcher SK, Mahjoub MR, Cole FS
Pediatr Res. 2018 Sep; 84(3)435-441. doi: 10.1038/s41390-018-0083-z.

PMID:
    29967526
    [PubMed - indexed for MEDLINE]
Related citations


Gene variants of the phosphatidylcholine synthesis pathway do not contribute to RDS in the Chinese population.
Chen YJ, Meyer J, Wambach JA, DePass K, Wegner DJ, Fan X, Zhang QY, Hillary H, Cole FS, Hamvas A
World J Pediatr. 2018 Feb; 14(1)52-56. doi: 10.1007/s12519-017-0109-3.

PMID:
    29411327
    [PubMed - indexed for MEDLINE]
Related citations


Infants with Atypical Presentations of Alveolar Capillary Dysplasia with Misalignment of the Pulmonary Veins Who Underwent Bilateral Lung Transplantation.
Towe CT, White FV, Grady RM, Sweet SC, Eghtesady P, Wegner DJ, Sen P, Szafranski P, Stankiewicz P, Hamvas A, Cole FS, Wambach JA
J Pediatr. 2018 Mar; 194158-164.e1. doi: 10.1016/j.jpeds.2017.10.026.

PMID:
    29198536
    [PubMed - indexed for MEDLINE]
Related citations


Neonatal Outcomes Differ after Spontaneous and Indicated Preterm Birth.
Stout MJ, Demaree D, Merfeld E, Tuuli MG, Wambach JA, Cole FS, Cahill AG
Am J Perinatol. 2018 Apr; 35(5)494-502. doi: 10.1055/s-0037-1608804.

PMID:
    29183099
    [PubMed - indexed for MEDLINE]
Related citations


Survival among children with "Lethal" congenital contracture syndrome 11 caused by novel mutations in the gliomedin gene (GLDN).
Wambach JA, Stettner GM, Haack TB, Writzl K, Škofljanec A, Maver A, Munell F, Ossowski S, Bosio M, Wegner DJ, Shinawi M, Baldridge D, Alhaddad B, Strom TM, Grange DK, Wilichowski E, Troxell R, Collins J, Warner BB, Schmidt RE, Pestronk A, Cole FS, Steinfeld R
Hum Mutat. 2017 Nov; 38(11)1477-1484. doi: 10.1002/humu.23297.

PMID:
    28726266
    [PubMed - indexed for MEDLINE]
Related citations


Outcomes of Lung Transplantation for Infants and Children with Genetic Disorders of Surfactant Metabolism.
Eldridge WB, Zhang Q, Faro A, Sweet SC, Eghtesady P, Hamvas A, Cole FS, Wambach JA
J Pediatr. 2017 May; 184157-164.e2. doi: 10.1016/j.jpeds.2017.01.017.

PMID:
    28215425
    [PubMed - indexed for MEDLINE]
Related citations


Accelerating Scientific Advancement for Pediatric Rare Lung Disease Research. Report from a National Institutes of Health-NHLBI Workshop, September 3 and 4, 2015.
Young LR, Trapnell BC, Mandl KD, Swarr DT, Wambach JA, Blaisdell CJ
Ann Am Thorac Soc. 2016 Dec; 13(12)385-393.

PMID:
    27925785
    [PubMed - indexed for MEDLINE]
Related citations


Functional Characterization of ATP-Binding Cassette Transporter A3 Mutations from Infants with Respiratory Distress Syndrome.
Wambach JA, Yang P, Wegner DJ, Heins HB, Kaliberova LN, Kaliberov SA, Curiel DT, White FV, Hamvas A, Hackett BP, Cole FS
Am J Respir Cell Mol Biol. 2016 Nov; 55(5)716-721.

PMID:
    27374344
    [PubMed - indexed for MEDLINE]
Related citations


Genetic Factors Contribute to Risk for Neonatal Respiratory Distress Syndrome among Moderately Preterm, Late Preterm, and Term Infants.
Shen CL, Zhang Q, Meyer Hudson J, Cole FS, Wambach JA
J Pediatr. 2016 May; 17269-74.e2. doi: 10.1016/j.jpeds.2016.01.031.

PMID:
    26935785
    [PubMed - indexed for MEDLINE]
Related citations


De novo 9q gain in an infant with tetralogy of Fallot with absent pulmonary valve: Patient report and review of congenital heart disease in 9q duplication syndrome.
Amarillo IE, O'Connor S, Lee CK, Willing M, Wambach JA
Am J Med Genet A. 2015 Dec; 167A(12)2966-74. doi: 10.1002/ajmg.a.37296.

PMID:
    26768185
    [PubMed - indexed for MEDLINE]
Related citations


Population-based frequency of surfactant dysfunction mutations in a native Chinese cohort.
Chen YJ, Wambach JA, DePass K, Wegner DJ, Chen SK, Zhang QY, Heins H, Cole FS, Hamvas A
World J Pediatr. 2016 May; 12(2)190-5. doi: 10.1007/s12519-015-0047-x.

PMID:
    26547207
    [PubMed - indexed for MEDLINE]
Related citations