Patient Portal

Jeffrey W. Brown, MD, PhD

Instructor, Medicine
Division of Gastroenterology

Specialty Areas


Board Certifications

Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital

Referral Information

Professional Consultation Only

Areas of Clinical Interest

General gastroenterology

  • Location(s)
  • Education
  • Publication & Research



Barnes-Jewish Hospital

1 Barnes-Jewish Hospital Plaza
St. Louis, MO 63110

Barnes-Jewish West County Hospital

12634 Olive Blvd.
Creve Coeur, MO 63141



Medical Degree: Boston University School of Medicine, Boston, MA 2012
PhD: Boston University School of Medicine, Boston, MA 2012

Publication & Research

Publication & Research

Das KK, Geng X, Brown JW, Morales-Oyarvide V, Huynh T, Pergolini I, Pitman MB, Ferrone C, Al Efishat M, Haviland D, Thompson E, Wolfgang C, Lennon AM, Allen P, Lillemoe KD, Fields RC, Hawkins WG, Liu J, Castillo CF, Das KM, Mino-Kenudson M. Cross Validation of the Monoclonal Antibody Das-1 in Identification of High-Risk Mucinous Pancreatic Cystic Lesions. Gastroenterology. 2019 Sep;157(3):720-730.e2. doi: 10.1053/j.gastro.2019.05.014. Epub 2019 Jun 5. PubMed PMID: 31175863; PubMed Central PMCID: PMC6707850.
Brown JW, Badahdah A, Iticovici M, Vickers TJ, Alvarado DM, Helmerhorst EJ, Oppenheim FG, Mills JC, Ciorba MA, Fleckenstein JM, Bullitt E. A Role for Salivary Peptides in the Innate Defense Against Enterotoxigenic Escherichia coli. J Infect Dis. 2018 Apr 11;217(9):1435-1441. doi: 10.1093/infdis/jiy032. PubMed PMID: 29528423; PubMed Central PMCID: PMC5894089.
Brown JW, Mills JC. Implantable synthetic organoid matrices for intestinal regeneration. Nat Cell Biol. 2017 Oct 31;19(11):1307-1308. doi: 10.1038/ncb3635. PubMed PMID: 29087385.
Cassell BE, Walker T, Alghamdi S, Bill J, Blais P, Boutté H, Brown JW, Sayuk GS, Gyawali CP. Do Consultants Follow Up on Tests They Recommend? Insights from an Academic Inpatient Gastrointestinal Consult Service. Dig Dis Sci. 2017 Jun;62(6):1448-1454. doi: 10.1007/s10620-017-4563-5. Epub 2017 Apr 8. PubMed PMID: 28391419; PubMed Central PMCID: PMC5890923.
Brown JW, Vipperla K, Vattikuti S, Kancherla D. An Unusual Case of Dyspnea in a Patient with Rheumatoid Arthritis. JSM Clinical Case Reports. 2016 April; 4(2):1098.
Brown JW, Bullitt E, Sriswasdi S, Harper S, Speicher DW, McKnight CJ. The Physiological Molecular Shape of Spectrin: A Compact Supercoil Resembling a Chinese Finger Trap. PLoS Comput Biol. 2015 Jun;11(6):e1004302. doi: 10.1371/journal.pcbi.1004302. eCollection 2015 Jun. PubMed PMID: 26067675; PubMed Central PMCID: PMC4466138.
Brown JW. Thwarting Antibiotic Resistance by Concealing the Host. Postdoc journal : a journal of postdoctoral research and postdoctoral affairs. 2014 May; 2(5):37-40.
Mitsche MA, Packer LE, Brown JW, Jiang ZG, Small DM, McKnight CJ. Surface tensiometry of apolipoprotein B domains at lipid interfaces suggests a new model for the initial steps in triglyceride-rich lipoprotein assembly. J Biol Chem. 2014 Mar 28;289(13):9000-12. doi: 10.1074/jbc.M113.540955. Epub 2014 Feb 10. PubMed PMID: 24515109; PubMed Central PMCID: PMC3979410.
Chen L, Brown JW, Mok YF, Hatters DM, McKnight CJ. The allosteric mechanism induced by protein kinase A (PKA) phosphorylation of dematin (band 4.9). J Biol Chem. 2013 Mar 22;288(12):8313-20. doi: 10.1074/jbc.M112.438861. Epub 2013 Jan 25. PubMed PMID: 23355471; PubMed Central PMCID: PMC3605649.
Dworkis DA, Brown SS, Gaeta JM, Brown JW, Gonzalez MH. Barriers to outpatient respiratory therapy among adult residents of emergency shelters. Ann Intern Med. 2012 Nov 6;157(9):679-80. doi: 10.7326/0003-4819-157-9-201211060-00025. PubMed PMID: 23128875.
Brown JW, Farelli JD, McKnight CJ. On the unyielding hydrophobic core of villin headpiece. Protein Sci. 2012 May;21(5):647-54. doi: 10.1002/pro.2048. Epub 2012 Mar 30. PubMed PMID: 22467489; PubMed Central PMCID: PMC3403462.
Brown JW, Farelli JD, McKnight CJ. On unsatisfied hydrogen bonds in the N-terminal subdomain of villin headpiece. J Mol Biol. 2011 Oct 28;413(3):543-7. doi: 10.1016/j.jmb.2011.08.024. Epub 2011 Aug 31. PubMed PMID: 21903098; PubMed Central PMCID: PMC3196028.
Brown JW, McKnight CJ. Identifying competitive protein antagonists for F-actin with reverse-phase high-performance liquid chromatography. Anal Biochem. 2010 Mar 1;398(1):117-9. doi: 10.1016/j.ab.2009.11.023. Epub 2009 Nov 20. PubMed PMID: 19932072; PubMed Central PMCID: PMC2812587.
Brown JW, McKnight CJ. Molecular model of the microvillar cytoskeleton and organization of the brush border. PLoS One2010 Feb 24;5(2):e9406doi: 10.1371/journal.pone.0009406. PubMed PMID: 20195380; PubMed Central PMCID: PMC2827561.
Brown JW, Vardar-Ulu D, McKnight CJ. How to arm a supervillin: designing F-actin binding activity into supervillin headpiece. J Mol Biol. 2009 Oct 30;393(3):608-18. doi: 10.1016/j.jmb.2009.08.018. Epub 2009 Aug 14. PubMed PMID: 19683541; PubMed Central PMCID: PMC2760644.
Grasko JM, Hooper AJ, Brown JW, McKnight CJ, Burnett JR. A novel missense HGD gene mutation, K57N, in a patient with alkaptonuria. Clin Chim Acta. 2009 May;403(1-2):254-6. doi: 10.1016/j.cca.2009.03.032. Epub 2009 Mar 21. PubMed PMID: 19306858.
Shen Q, Brown JW, Richardson A, Hagen K. The Molecular Structure and Conformational of Trichloronitromethane as Determined by Gas-Phase Electron Diffraction and Theoretical Calculations. Journal of Molecular Structure. 2007; 830:204-7.
Shen Q, Brown JW, Malona JA, Cochran JC, Richardson AD. Molecular structure and conformation of chloronitromethane as determined by gas-phase electron diffraction and theoretical calculations. J Phys Chem A. 2006 Jun 15;110(23):7491-5. doi: 10.1021/jp061100f. PubMed PMID: 16759140.

Areas of Research Interest

Metaplasia and cancer biology