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Faculty Physicians

Jeffrey S. Crippin, MD

Marilyn Bornefeld Endowed Chair in GI Research and Treatment
Professor, Medicine
Division of Gastroenterology
Medical Director, Liver Transplantation
Co-Director, GI Center, Clinical Operations

Specialty Areas

Gastroenterology
Liver Diseases
Liver Transplantation

Board Certifications

Gastroenterology
Internal Medicine
Transplant Hepatology Certificate of Added Qualification

Areas of Clinical Interest

Liver transplant, acute/chronic liver disease, hepatitis, cirrhosis, liver transplantation

  • Maps & Directions
  • Education
  • Publication & Research
  • Financial Disclosures

Maps & Directions

Maps & Directions

Barnes-Jewish West County Hospital
Medical Building Two

10 Barnes West Drive
Creve Coeur, MO 63141

Suite: Suite 200
Office Phone: 314-747-2066
Fax: 314-747-1277

Center for Advanced Medicine
Gastrointestinal Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 8
Office Phone: 314-454-8160
Fax: 314-454-5108

Education

Education

Fellowship: Gastroenterology, Mayo Clinic, Rochester, Minnesota 1991
Chief Resident: Internal Medicine, Kansas University Medical Center, Kansas 1988
Residency: Kansas University Medical Center, Kansas City, Kansas 1987
Medical Degree: University of Kansas, Kansas City, Kansas 1984
B.S.: University of Notre Dame, Notre Dame, Indiana 1980

Publication & Research

Publication & Research

Assessment of hepatitis C risk factors and infection prevalence in a jail population.
Wenger PJ, Rottnek F, Parker T, Crippin JS
Am J Public Health. 2014 Sep; 104(9)1722-7. doi: 10.2105/AJPH.2014.301996.

PMID:
    25033142
    [PubMed - indexed for MEDLINE]
Related citations


Liver volume in the cirrhotic patient: does size matter?
Hagan MT, Sayuk GS, Lisker-Melman M, Korenblat KM, Kerr TA, Chapman WC, Crippin JS
Dig Dis Sci. 2014 Apr; 59(4)886-91. doi: 10.1007/s10620-014-3038-1.

PMID:
    24504591
    [PubMed - indexed for MEDLINE]
Related citations


Hepatitis C virus-induced changes in microRNA 107 (miRNA-107) and miRNA-449a modulate CCL2 by targeting the interleukin-6 receptor complex in hepatitis.
Sarma NJ, Tiriveedhi V, Crippin JS, Chapman WC, Mohanakumar T
J Virol. 2014 Apr; 88(7)3733-43. doi: 10.1128/JVI.03060-13.

PMID:
    24429361
    [PubMed - indexed for MEDLINE]
Related citations


Recurrent hepatic epithelioid hemangioendothelioma after orthotopic liver transplantation.
Rude MK, Watson R, Crippin JS
Hepatology. 2014 May; 59(5)2050-2. doi: 10.1002/hep.26891.

PMID:
    24122824
    [PubMed - indexed for MEDLINE]
Related citations


Hepatitis C virus induced miR200c down modulates FAP-1, a negative regulator of Src signaling and promotes hepatic fibrosis.
Ramachandran S, Ilias Basha H, Sarma NJ, Lin Y, Crippin JS, Chapman WC, Mohanakumar T
PLoS One. 2013; 8(8)e70744. doi: 10.1371/journal.pone.0070744.

PMID:
    23950995
    [PubMed - indexed for MEDLINE]
Related citations


Parenchymal alterations in cirrhotic livers in patients with hepatopulmonary syndrome or portopulmonary hypertension.
Ma C, Crippin JS, Chapman WC, Korenblat K, Vachharajani N, Gunter KL, Brunt EM
Liver Transpl. 2013 Jul; 19(7)741-50. doi: 10.1002/lt.23632.

PMID:
    23463612
    [PubMed - indexed for MEDLINE]
Related citations


Once weekly fluconazole for antifungal prophylaxis post-liver transplantation.
Trudeau RE, Bowman LJ, Wills AR, Crippin JS, Chapman WC, Anderson C
HPB (Oxford). 2013 Jul; 15(7)541-7. doi: 10.1111/hpb.12006.

PMID:
    23458063
    [PubMed - indexed for MEDLINE]
Related citations


Hepatitis C virus mediated changes in miRNA-449a modulates inflammatory biomarker YKL40 through components of the NOTCH signaling pathway.
Sarma NJ, Tiriveedhi V, Subramanian V, Shenoy S, Crippin JS, Chapman WC, Mohanakumar T
PLoS One. 2012; 7(11)e50826. doi: 10.1371/journal.pone.0050826.

PMID:
    23226395
    [PubMed - indexed for MEDLINE]
Related citations


A consolidated biovigilance system for blood, tissue and organs: one size does not fit all.
Pruett TL, Blumberg EA, Cohen DJ, Crippin JS, Freeman RB, Hanto DW, Mulligan DC, Green MD
Am J Transplant. 2012 May; 12(5)1099-101. doi: 10.1111/j.1600-6143.2011.03907.x.

PMID:
    22487495
    [PubMed - indexed for MEDLINE]
Related citations


Reduced uptake of FDOPA PET in end-stage liver disease with elevated manganese levels.
Criswell SR, Perlmutter JS, Crippin JS, Videen TO, Moerlein SM, Flores HP, Birke AM, Racette BA
Arch Neurol. 2012 Mar; 69(3)394-7. doi: 10.1001/archneurol.2011.771.

PMID:
    22410448
    [PubMed - indexed for MEDLINE]
Related citations


Temporal association between increased virus-specific Th17 response and spontaneous recovery from recurrent hepatitis C in a liver transplant recipient.
Seetharam AB, Borg BB, Subramanian V, Chapman WC, Crippin JS, Mohanakumar T
Transplantation. 2011 Dec 27; 92(12)1364-70. doi: 10.1097/TP.0b013e31823817f5.

PMID:
    22082818
    [PubMed - indexed for MEDLINE]
Related citations


Donor graft steatosis influences immunity to hepatitis C virus and allograft outcome after liver transplantation.
Subramanian V, Seetharam AB, Vachharajani N, Tiriveedhi V, Angaswamy N, Ramachandran S, Crippin JS, Shenoy S, Chapman WC, Mohanakumar T, Anderson CD
Transplantation. 2011 Dec 15; 92(11)1259-68. doi: 10.1097/TP.0b013e318235a1ab.

PMID:
    22011763
    [PubMed - indexed for MEDLINE]
Related citations


Characterization of HCV-specific CD4+Th17 immunity in recurrent hepatitis C-induced liver allograft fibrosis.
Basha HI, Subramanian V, Seetharam A, Nath DS, Ramachandran S, Anderson CD, Shenoy S, Chapman WC, Crippin JS, Mohanakumar T
Am J Transplant. 2011 Apr; 11(4)775-85. doi: 10.1111/j.1600-6143.2011.03458.x.

PMID:
    21446979
    [PubMed - indexed for MEDLINE]
Related citations


Immune response to extracellular matrix collagen in chronic hepatitis C-induced liver fibrosis.
Borg BB, Seetharam A, Subramanian V, Basha HI, Lisker-Melman M, Korenblat K, Anderson CD, Shenoy S, Chapman WC, Crippin JS, Mohanakumar T
Liver Transpl. 2011 Jul; 17(7)814-23. doi: 10.1002/lt.22303.

PMID:
    21425431
    [PubMed - indexed for MEDLINE]
Related citations


What factors determine the severity of hepatitis A-related acute liver failure?
Ajmera V, Xia G, Vaughan G, Forbi JC, Ganova-Raeva LM, Khudyakov Y, Opio CK, Taylor R, Restrepo R, Munoz S, Fontana RJ, Lee WM, Acute Liver Failure Study Group
J Viral Hepat. 2011 Jul; 18(7)e167-74. doi: 10.1111/j.1365-2893.2010.01410.x.

PMID:
    21143345
    [PubMed - indexed for MEDLINE]
Related citations


The psychiatric diagnosis of alcohol abuse and the medical diagnosis of alcoholic related liver disease: effects on liver transplant survival.
Rowley AA, Hong BA, Chapman W, Crippin JS
J Clin Psychol Med Settings. 2010 Sep; 17(3)195-202. doi: 10.1007/s10880-010-9201-8.

PMID:
    20502950
    [PubMed - indexed for MEDLINE]
Related citations


The role of etiology in the hyperamylasemia of acute liver failure.
Coté GA, Gottstein JH, Daud A, Blei AT, Acute Liver Failure Study Group
Am J Gastroenterol. 2009 Mar; 104(3)592-7. doi: 10.1038/ajg.2008.84.

PMID:
    19223884
    [PubMed - indexed for MEDLINE]
Related citations


Outcomes of neoadjuvant transarterial chemoembolization to downstage hepatocellular carcinoma before liver transplantation.
Chapman WC, Majella Doyle MB, Stuart JE, Vachharajani N, Crippin JS, Anderson CD, Lowell JA, Shenoy S, Darcy MD, Brown DB
Ann Surg. 2008 Oct; 248(4)617-25. doi: 10.1097/SLA.0b013e31818a07d4.

PMID:
    18936575
    [PubMed - indexed for MEDLINE]
Related citations


Screening for Wilson disease in acute liver failure: a comparison of currently available diagnostic tests.
Korman JD, Volenberg I, Balko J, Webster J, Schiodt FV, Squires RH Jr, Fontana RJ, Lee WM, Schilsky ML, Pediatric and Adult Acute Liver Failure Study Groups
Hepatology. 2008 Oct; 48(4)1167-74. doi: 10.1002/hep.22446.

PMID:
    18798336
    [PubMed - indexed for MEDLINE]
Related citations


Liver transplant for hepatitis C virus: effect of using older donor grafts on short- and medium-term survival.
Doyle MB, Anderson CD, Vachharajani N, Lowell JA, Shenoy S, Lisker-Melman M, Korenblat K, Crippin JS, Chapman WC
Arch Surg. 2008 Jul; 143(7)679-85; discussion 685. doi: 10.1001/archsurg.143.7.679.

PMID:
    18645111
    [PubMed - indexed for MEDLINE]
Related citations

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following earned financial interests during calendar year 2014.

Company Name: Genentech

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $25,001 - $50,000

Reporting Date: May 01, 2015


Company Name: Gilead

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $50,001 - $100,000

Reporting Date: May 01, 2015