Patient Portal

Jeffrey Parker Henderson, MD, PhD

Associate Professor, Medicine and Molecular Biology
Division of Infectious Diseases

Specialty Areas

Infectious Diseases

Board Certifications

Infectious Diseases
Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Infectious diseases

  • Location(s)
  • Education
  • Publication & Research

Location(s)

Location(s)

Taylor Ave. Building Extension

620 South Taylor Ave.
Suite 100
St. Louis, MO 63110

Office Phone: 314-747-1206
Fax: 314-222-6252

Education

Education

Fellowship: Infectious Diseases, Washington University School of Medicine, St. Louis, Missouri 2006
Residency: Barnes-Jewish Hospital at Washington University School of Medicine, St. Louis, Missouri 2004
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 2002
Ph.D.: Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri 2002
B.S.: University of Wisconsin, Madison, Wisconsin 1994

Publication & Research

Publication & Research

Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2.
Case JB, Rothlauf PW, Chen RE, Liu Z, Zhao H, Kim AS, Bloyet LM, Zeng Q, Tahan S, Droit L, Ilagan MXG, Tartell MA, Amarasinghe G, Henderson JP, Miersch S, Ustav M, Sidhu S, Virgin HW, Wang D, Ding S, Corti D, Theel ES, Fremont DH, Diamond MS, Whelan SPJ
bioRxiv. 2020 May 18; pii: 2020.05.18.102038. doi: 10.1101/2020.05.18.102038.

PMID:
    32511401
    [PubMed]
Related citations


Deployment of convalescent plasma for the prevention and treatment of COVID-19.
Bloch EM, Shoham S, Casadevall A, Sachais BS, Shaz B, Winters JL, van Buskirk C, Grossman BJ, Joyner M, Henderson JP, Pekosz A, Lau B, Wesolowski A, Katz L, Shan H, Auwaerter PG, Thomas D, Sullivan DJ, Paneth N, Gehrie E, Spitalnik S, Hod EA, Pollack L, Nicholson WT, Pirofski LA, Bailey JA, Tobian AA
J Clin Invest. 2020 Jun 1; 130(6)2757-2765. doi: 10.1172/JCI138745.

PMID:
    32254064
    [PubMed - indexed for MEDLINE]
Related citations


Site-Specific Siderocalin Binding to Ferric and Ferric-Free Enterobactin As Revealed by Mass Spectrometry.
Guo C, Steinberg LK, Cheng M, Song JH, Henderson JP, Gross ML
ACS Chem Biol. 2020 May 15; 15(5)1154-1160. doi: 10.1021/acschembio.9b00741.

PMID:
    31869199
    [PubMed - in process]
Related citations


Metabolomic networks connect host-microbiome processes to human Clostridioides difficile infections.
Robinson JI, Weir WH, Crowley JR, Hink T, Reske KA, Kwon JH, Burnham CD, Dubberke ER, Mucha PJ, Henderson JP
J Clin Invest. 2019 Aug 12; 129(9)3792-3806. doi: 10.1172/JCI126905.

PMID:
    31403473
    [PubMed - indexed for MEDLINE]
Related citations


A Culture-Independent Analysis of the Microbiota of Female Interstitial Cystitis/Bladder Pain Syndrome Participants in the MAPP Research Network.
Nickel JC, Stephens-Shields AJ, Landis JR, Mullins C, van Bokhoven A, Lucia MS, Henderson JP, Sen B, Krol JE, Ehrlich GD, MAPP Research Network.
J Clin Med. 2019 Mar 26; 8(3)pii: E415. doi: 10.3390/jcm8030415.

PMID:
    30917614
    [PubMed]
Related citations


The Widely Used Antimicrobial Triclosan Induces High Levels of Antibiotic Tolerance <i>In Vitro</i> and Reduces Antibiotic Efficacy up to 100-Fold <i>In Vivo</i>.
Westfall C, Flores-Mireles AL, Robinson JI, Lynch AJL, Hultgren S, Henderson JP, Levin PA
Antimicrob Agents Chemother. 2019 May; 63(5)pii: e02312-18. doi: 10.1128/AAC.02312-18.

PMID:
    30782996
    [PubMed - indexed for MEDLINE]
Related citations


YbtT is a low-specificity type II thioesterase that maintains production of the metallophore yersiniabactin in pathogenic enterobacteria.
Ohlemacher SI, Xu Y, Kober DL, Malik M, Nix JC, Brett TJ, Henderson JP
J Biol Chem. 2018 Dec 21; 293(51)19572-19585. doi: 10.1074/jbc.RA118.005752.

PMID:
    30355735
    [PubMed - indexed for MEDLINE]
Related citations


Clostridium difficile colonization among patients with clinically significant diarrhea and no identifiable cause of diarrhea.
Dubberke ER, Reske KA, Hink T, Kwon JH, Cass C, Bongu J, Burnham CD, Henderson JP
Infect Control Hosp Epidemiol. 2018 Nov; 39(11)1330-1333. doi: 10.1017/ice.2018.225.

PMID:
    30226126
    [PubMed - indexed for MEDLINE]
Related citations


Uropathogenic enterobacteria use the yersiniabactin metallophore system to acquire nickel.
Robinson AE, Lowe JE, Koh EI, Henderson JP
J Biol Chem. 2018 Sep 28; 293(39)14953-14961. doi: 10.1074/jbc.RA118.004483.

PMID:
    30108176
    [PubMed - indexed for MEDLINE]
Related citations


The iron hand of uropathogenic Escherichia coli: the role of transition metal control in virulence.
Robinson AE, Heffernan JR, Henderson JP
Future Microbiol. 2018 Jun 1; 13745-756. doi: 10.2217/fmb-2017-0295.

PMID:
    29870278
    [PubMed - indexed for MEDLINE]
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A mass spectrometry based transport assay for studying EmrE transport of unlabeled substrates.
Robinson AE, Henderson JP, Henzler-Wildman KA
Anal Biochem. 2018 May 15; 549130-135. doi: 10.1016/j.ab.2018.03.017.

PMID:
    29559333
    [PubMed - indexed for MEDLINE]
Related citations


Individualizing Urinary Incontinence Treatment: Research Needs Identified at NIDDK Workshop.
Norton JM, Bradley CS, Brady SS, Brubaker L, Gossett D, Henderson JP, Mazloomdoost D, Musil CM, Rovner E, Bavendam T
J Urol. 2018 Jun; 199(6)1405-1407. doi: 10.1016/j.juro.2017.11.118.

PMID:
    29246733
    [PubMed - indexed for MEDLINE]
Related citations


Enterobacteria secrete an inhibitor of Pseudomonas virulence during clinical bacteriuria.
Ohlemacher SI, Giblin DE, d'Avignon DA, Stapleton AE, Trautner BW, Henderson JP
J Clin Invest. 2017 Nov 1; 127(11)4018-4030. doi: 10.1172/JCI92464.

PMID:
    28945201
    [PubMed - indexed for MEDLINE]
Related citations


Copper import in Escherichia coli by the yersiniabactin metallophore system.
Koh EI, Robinson AE, Bandara N, Rogers BE, Henderson JP
Nat Chem Biol. 2017 Sep; 13(9)1016-1021. doi: 10.1038/nchembio.2441.

PMID:
    28759019
    [PubMed - indexed for MEDLINE]
Related citations


Human Metabolome-derived Cofactors Are Required for the Antibacterial Activity of Siderocalin in Urine.
Shields-Cutler RR, Crowley JR, Miller CD, Stapleton AE, Cui W, Henderson JP
J Biol Chem. 2016 Dec 9; 291(50)25901-25910.

PMID:
    27780864
    [PubMed - indexed for MEDLINE]
Related citations


Symptom Variability and Early Symptom Regression in the MAPP Study: A Prospective Study of Urological Chronic Pelvic Pain Syndrome.
Stephens-Shields AJ, Clemens JQ, Jemielita T, Farrar J, Sutcliffe S, Hou X, Landis JR, MAPP Research Network.
J Urol. 2016 Nov; 196(5)1450-1455. doi: 10.1016/j.juro.2016.04.070.

PMID:
    27131464
    [PubMed - indexed for MEDLINE]
Related citations


Urinary Metabolomics Identifies a Molecular Correlate of Interstitial Cystitis/Bladder Pain Syndrome in a Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network Cohort.
Parker KS, Crowley JR, Stephens-Shields AJ, van Bokhoven A, Lucia MS, Lai HH, Andriole GL, Hooton TM, Mullins C, Henderson JP
EBioMedicine. 2016 May; 7167-74. doi: 10.1016/j.ebiom.2016.03.040.

PMID:
    27322470
    [PubMed - indexed for MEDLINE]
Related citations


Network Analysis Reveals Sex- and Antibiotic Resistance-Associated Antivirulence Targets in Clinical Uropathogens.
Parker KS, Wilson JD, Marschall J, Mucha PJ, Henderson JP
ACS Infect Dis. 2015 Nov 13; 1(11)523-532.

PMID:
    26985454
    [PubMed]
Related citations


Prevalence of Asymptomatic Bacteriuria in Hospitalized Patients.
Trevino SE, Henderson JP, Wu J, Cass C, Marschall J
Infect Control Hosp Epidemiol. 2016 Jun; 37(6)749-51. doi: 10.1017/ice.2016.56.

PMID:
    26984672
    [PubMed - indexed for MEDLINE]
Related citations


The Yersiniabactin-Associated ATP Binding Cassette Proteins YbtP and YbtQ Enhance Escherichia coli Fitness during High-Titer Cystitis.
Koh EI, Hung CS, Henderson JP
Infect Immun. 2016 May; 84(5)1312-1319. doi: 10.1128/IAI.01211-15.

PMID:
    26883590
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Pathophysiology of enteric gram negative infections