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Jeffrey Parker Henderson, MD, PhD

Associate Professor, Medicine and Molecular Biology
Division of Infectious Diseases

Specialty Areas

Infectious Diseases

Board Certifications

Infectious Diseases
Internal Medicine

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Infectious diseases

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Taylor Ave. Building Extension

620 South Taylor Ave.
Suite 100
St. Louis, MO 63110

Office Phone: 314-747-1206
Fax: 314-222-6252

Education

Education

Fellowship: Infectious Diseases, Washington University School of Medicine, St. Louis, Missouri 2006
Residency: Barnes-Jewish Hospital at Washington University School of Medicine, St. Louis, Missouri 2004
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 2002
Ph.D.: Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri 2002
B.S.: University of Wisconsin, Madison, Wisconsin 1994

Publication & Research

Publication & Research

Enterobacteria secrete an inhibitor of Pseudomonas virulence during clinical bacteriuria.
Ohlemacher SI, Giblin DE, d'Avignon DA, Stapleton AE, Trautner BW, Henderson JP
J Clin Invest. 2017 Nov 1; 127(11)4018-4030. doi: 10.1172/JCI92464.

PMID:
    28945201
    [PubMed - in process]
Related citations


Copper import in Escherichia coli by the yersiniabactin metallophore system.
Koh EI, Robinson AE, Bandara N, Rogers BE, Henderson JP
Nat Chem Biol. 2017 Sep; 13(9)1016-1021. doi: 10.1038/nchembio.2441.

PMID:
    28759019
    [PubMed - indexed for MEDLINE]
Related citations


Human Metabolome-derived Cofactors Are Required for the Antibacterial Activity of Siderocalin in Urine.
Shields-Cutler RR, Crowley JR, Miller CD, Stapleton AE, Cui W, Henderson JP
J Biol Chem. 2016 Dec 9; 291(50)25901-25910.

PMID:
    27780864
    [PubMed - indexed for MEDLINE]
Related citations


Symptom Variability and Early Symptom Regression in the MAPP Study: A Prospective Study of Urological Chronic Pelvic Pain Syndrome.
Stephens-Shields AJ, Clemens JQ, Jemielita T, Farrar J, Sutcliffe S, Hou X, Landis JR, MAPP Research Network.
J Urol. 2016 Nov; 196(5)1450-1455. doi: 10.1016/j.juro.2016.04.070.

PMID:
    27131464
    [PubMed - in process]
Related citations


Urinary Metabolomics Identifies a Molecular Correlate of Interstitial Cystitis/Bladder Pain Syndrome in a Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network Cohort.
Parker KS, Crowley JR, Stephens-Shields AJ, van Bokhoven A, Lucia MS, Lai HH, Andriole GL, Hooton TM, Mullins C, Henderson JP
EBioMedicine. 2016 May; 7167-74. doi: 10.1016/j.ebiom.2016.03.040.

PMID:
    27322470
    [PubMed - indexed for MEDLINE]
Related citations


Network Analysis Reveals Sex- and Antibiotic Resistance-Associated Antivirulence Targets in Clinical Uropathogens.
Parker KS, Wilson JD, Marschall J, Mucha PJ, Henderson JP
ACS Infect Dis. 2015 Nov 13; 1(11)523-532.

PMID:
    26985454
    [PubMed]
Related citations


Prevalence of Asymptomatic Bacteriuria in Hospitalized Patients.
Trevino SE, Henderson JP, Wu J, Cass C, Marschall J
Infect Control Hosp Epidemiol. 2016 Jun; 37(6)749-51. doi: 10.1017/ice.2016.56.

PMID:
    26984672
    [PubMed - in process]
Related citations


The Yersiniabactin-Associated ATP Binding Cassette Proteins YbtP and YbtQ Enhance Escherichia coli Fitness during High-Titer Cystitis.
Koh EI, Hung CS, Henderson JP
Infect Immun. 2016 May; 84(5)1312-9. doi: 10.1128/IAI.01211-15.

PMID:
    26883590
    [PubMed - indexed for MEDLINE]
Related citations


Perceptions and behaviours of infectious diseases physicians when managing urinary tract infections due to MDR organisms.
Trevino SE, Babcock HM, Henderson JP, Lane MA, Beekmann SE, Polgreen PM, Marschall J
J Antimicrob Chemother. 2015 Dec; 70(12)3397-400. doi: 10.1093/jac/dkv271.

PMID:
    26349519
    [PubMed - indexed for MEDLINE]
Related citations


Deconvoluting heme biosynthesis to target blood-stage malaria parasites.
Sigala PA, Crowley JR, Henderson JP, Goldberg DE
Elife. 2015 Jul 14; 4doi: 10.7554/eLife.09143.

PMID:
    26173178
    [PubMed - indexed for MEDLINE]
Related citations


Low correlation between self-report and medical record documentation of urinary tract infection symptoms.
Echaiz JF, Cass C, Henderson JP, Babcock HM, Marschall J
Am J Infect Control. 2015 Sep 1; 43(9)983-6. doi: 10.1016/j.ajic.2015.04.208.

PMID:
    26088770
    [PubMed - in process]
Related citations


Microbial Copper-binding Siderophores at the Host-Pathogen Interface.
Koh EI, Henderson JP
J Biol Chem. 2015 Jul 31; 290(31)18967-74. doi: 10.1074/jbc.R115.644328.

PMID:
    26055720
    [PubMed - indexed for MEDLINE]
Related citations


Human Urinary Composition Controls Antibacterial Activity of Siderocalin.
Shields-Cutler RR, Crowley JR, Hung CS, Stapleton AE, Aldrich CC, Marschall J, Henderson JP
J Biol Chem. 2015 Jun 26; 290(26)15949-60. doi: 10.1074/jbc.M115.645812.

PMID:
    25861985
    [PubMed - indexed for MEDLINE]
Related citations


Metal selectivity by the virulence-associated yersiniabactin metallophore system.
Koh EI, Hung CS, Parker KS, Crowley JR, Giblin DE, Henderson JP
Metallomics. 2015 Jun; 7(6)1011-22. doi: 10.1039/c4mt00341a.

PMID:
    25824627
    [PubMed - indexed for MEDLINE]
Related citations


Relationship between chronic nonurological associated somatic syndromes and symptom severity in urological chronic pelvic pain syndromes: baseline evaluation of the MAPP study.
Krieger JN, Stephens AJ, Landis JR, Clemens JQ, Kreder K, Lai HH, Afari N, Rodríguez L, Schaeffer A, Mackey S, Andriole GL, Williams DA, MAPP Research Network.
J Urol. 2015 Apr; 193(4)1254-62. doi: 10.1016/j.juro.2014.10.086.

PMID:
    25444992
    [PubMed - indexed for MEDLINE]
Related citations


The heme biosynthesis pathway is essential for Plasmodium falciparum development in mosquito stage but not in blood stages.
Ke H, Sigala PA, Miura K, Morrisey JM, Mather MW, Crowley JR, Henderson JP, Goldberg DE, Long CA, Vaidya AB
J Biol Chem. 2014 Dec 12; 289(50)34827-37. doi: 10.1074/jbc.M114.615831.

PMID:
    25352601
    [PubMed - indexed for MEDLINE]
Related citations


The MAPP research network: design, patient characterization and operations.
Landis JR, Williams DA, Lucia MS, Clauw DJ, Naliboff BD, Robinson NA, van Bokhoven A, Sutcliffe S, Schaeffer AJ, Rodriguez LV, Mayer EA, Lai HH, Krieger JN, Kreder KJ, Afari N, Andriole GL, Bradley CS, Griffith JW, Klumpp DJ, Hong BA, Lutgendorf SK, Buchwald D, Yang CC, Mackey S, Pontari MA, Hanno P, Kusek JW, Mullins C, Clemens JQ, MAPP Research Network Study Group.
BMC Urol. 2014 Aug 1; 1458. doi: 10.1186/1471-2490-14-58.

PMID:
    25085119
    [PubMed - indexed for MEDLINE]
Related citations


The MAPP research network: a novel study of urologic chronic pelvic pain syndromes.
Clemens JQ, Mullins C, Kusek JW, Kirkali Z, Mayer EA, Rodríguez LV, Klumpp DJ, Schaeffer AJ, Kreder KJ, Buchwald D, Andriole GL, Lucia MS, Landis JR, Clauw DJ, MAPP Research Network Study Group.
BMC Urol. 2014 Aug 1; 1457. doi: 10.1186/1471-2490-14-57.

PMID:
    25085007
    [PubMed - indexed for MEDLINE]
Related citations


Pathogenic adaptations to host-derived antibacterial copper.
Chaturvedi KS, Henderson JP
Front Cell Infect Microbiol. 2014; 43. doi: 10.3389/fcimb.2014.00003.

PMID:
    24551598
    [PubMed - indexed for MEDLINE]
Related citations


Metabolomic analysis of siderophore cheater mutants reveals metabolic costs of expression in uropathogenic Escherichia coli.
Lv H, Hung CS, Henderson JP
J Proteome Res. 2014 Mar 7; 13(3)1397-404. doi: 10.1021/pr4009749.

PMID:
    24476533
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Pathophysiology of enteric gram negative infections