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Jeffrey J. Atkinson, MD

Associate Professor, Medicine
Division of Pulmonary and Critical Care Medicine

Specialty Areas

Critical Care Medicine
Pulmonary Disease

Board Certifications

Internal Medicine
Pulmonary and Critical Care
Critical Care

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Cystic fibrosis, ciliary dyskinesia

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Lung Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 8
Office Phone: 314-454-8917

Education

Education

Fellowship: Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, Missouri 2002
Chief Resident: University Hospital of Cleveland, Cleveland, Ohio 1998
Residency: University Hospital of Cleveland, Cleveland, Ohio 1997
Medical Degree: Hahnemann University, Philadelphia, Pennsylvania 1994
B.S.: Biology, Loyola College, Baltimore, Maryland 1990

Publication & Research

Publication & Research

Mechanisms Underlying HIV-Associated Noninfectious Lung Disease.
Presti RM, Flores SC, Palmer BE, Atkinson JJ, Lesko CR, Lau B, Fontenot AP, Roman J, McDyer JF, Twigg HL 3rd
Chest. 2017 Nov; 152(5)1053-1060. doi: 10.1016/j.chest.2017.04.154.

PMID:
    28427967
    [PubMed - in process]
Related citations


PET-based Imaging of Chemokine Receptor 2 in Experimental and Disease-related Lung Inflammation.
Liu Y, Gunsten SP, Sultan DH, Luehmann HP, Zhao Y, Blackwell TS, Bollermann-Nowlis Z, Pan JH, Byers DE, Atkinson JJ, Kreisel D, Holtzman MJ, Gropler RJ, Combadiere C, Brody SL
Radiology. 2017 Jun; 283(3)758-768. doi: 10.1148/radiol.2016161409.

PMID:
    28045644
    [PubMed - indexed for MEDLINE]
Related citations


Significant Interference in Mass Cytometry from Medicinal Iodine in Human Lung.
Keller BC, Presti RM, Byers DE, Atkinson JJ
Am J Respir Cell Mol Biol. 2016 Jul; 55(1)150-1. doi: 10.1165/rcmb.2015-0403LE.

PMID:
    27362453
    [PubMed - in process]
Related citations


PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection.
Zhang Y, Mao D, Roswit WT, Jin X, Patel AC, Patel DA, Agapov E, Wang Z, Tidwell RM, Atkinson JJ, Huang G, McCarthy R, Yu J, Yun NE, Paessler S, Lawson TG, Omattage NS, Brett TJ, Holtzman MJ
Nat Immunol. 2015 Dec; 16(12)1215-27. doi: 10.1038/ni.3279.

PMID:
    26479788
    [PubMed - indexed for MEDLINE]
Related citations


Controversies in choledochal malformation.
Atkinson JJ, Davenport M
S Afr Med J. 2014 Nov; 104(11 Pt 2)816-9.

PMID:
    26038796
    [PubMed - indexed for MEDLINE]
Related citations


Matrix metalloproteinase-9 activates TGF-β and stimulates fibroblast contraction of collagen gels.
Kobayashi T, Kim H, Liu X, Sugiura H, Kohyama T, Fang Q, Wen FQ, Abe S, Wang X, Atkinson JJ, Shipley JM, Senior RM, Rennard SI
Am J Physiol Lung Cell Mol Physiol. 2014 Jun 1; 306(11)L1006-15. doi: 10.1152/ajplung.00015.2014.

PMID:
    24705725
    [PubMed - indexed for MEDLINE]
Related citations


Quantification of human lung structure and physiology using hyperpolarized 129Xe.
Chang YV, Quirk JD, Ruset IC, Atkinson JJ, Hersman FW, Woods JC
Magn Reson Med. 2014 Jan; 71(1)339-44. doi: 10.1002/mrm.24992.

PMID:
    24155277
    [PubMed - indexed for MEDLINE]
Related citations


Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia.
Austin-Tse C, Halbritter J, Zariwala MA, Gilberti RM, Gee HY, Hellman N, Pathak N, Liu Y, Panizzi JR, Patel-King RS, Tritschler D, Bower R, O'Toole E, Porath JD, Hurd TW, Chaki M, Diaz KA, Kohl S, Lovric S, Hwang DY, Braun DA, Schueler M, Airik R, Otto EA, Leigh MW, Noone PG, Carson JL, Davis SD, Pittman JE, Ferkol TW, Atkinson JJ, Olivier KN, Sagel SD, Dell SD, Rosenfeld M, Milla CE, Loges NT, Omran H, Porter ME, King SM, Knowles MR, Drummond IA, Hildebrandt F
Am J Hum Genet. 2013 Oct 3; 93(4)672-86. doi: 10.1016/j.ajhg.2013.08.015.

PMID:
    24094744
    [PubMed - indexed for MEDLINE]
Related citations


FDG PET imaging in cystic fibrosis.
Chen DL, Atkinson JJ, Ferkol TW
Semin Nucl Med. 2013 Nov; 43(6)412-9. doi: 10.1053/j.semnuclmed.2013.06.002.

PMID:
    24094708
    [PubMed - indexed for MEDLINE]
Related citations


Standardizing nasal nitric oxide measurement as a test for primary ciliary dyskinesia.
Leigh MW, Hazucha MJ, Chawla KK, Baker BR, Shapiro AJ, Brown DE, Lavange LM, Horton BJ, Qaqish B, Carson JL, Davis SD, Dell SD, Ferkol TW, Atkinson JJ, Olivier KN, Sagel SD, Rosenfeld M, Milla C, Lee HS, Krischer J, Zariwala MA, Knowles MR
Ann Am Thorac Soc. 2013 Dec; 10(6)574-81. doi: 10.1513/AnnalsATS.201305-110OC.

PMID:
    24024753
    [PubMed - indexed for MEDLINE]
Related citations


Anti-PcrV antibody in cystic fibrosis: a novel approach targeting Pseudomonas aeruginosa airway infection.
Milla CE, Chmiel JF, Accurso FJ, VanDevanter DR, Konstan MW, Yarranton G, Geller DE, KB001 Study Group.
Pediatr Pulmonol. 2014 Jul; 49(7)650-8. doi: 10.1002/ppul.22890.

PMID:
    24019259
    [PubMed - indexed for MEDLINE]
Related citations


Microfibril-associated glycoprotein 2 (MAGP2) loss of function has pleiotropic effects in vivo.
Combs MD, Knutsen RH, Broekelmann TJ, Toennies HM, Brett TJ, Miller CA, Kober DL, Craft CS, Atkinson JJ, Shipley JM, Trask BC, Mecham RP
J Biol Chem. 2013 Oct 4; 288(40)28869-80. doi: 10.1074/jbc.M113.497727.

PMID:
    23963447
    [PubMed - indexed for MEDLINE]
Related citations


Accurate measurement of small airways on low-dose thoracic CT scans in smokers.
Lutey BA, Conradi SH, Atkinson JJ, Zheng J, Schechtman KB, Senior RM, Gierada DS
Chest. 2013 May; 143(5)1321-1329. doi: 10.1378/chest.12-0034.

PMID:
    23172175
    [PubMed - indexed for MEDLINE]
Related citations


MT1-MMP-dependent remodeling of cardiac extracellular matrix structure and function following myocardial infarction.
Koenig GC, Rowe RG, Day SM, Sabeh F, Atkinson JJ, Cooke KR, Weiss SJ
Am J Pathol. 2012 May; 180(5)1863-78. doi: 10.1016/j.ajpath.2012.01.022.

PMID:
    22464947
    [PubMed - indexed for MEDLINE]
Related citations


Imaging lung microstructure in mice with hyperpolarized 3He diffusion MRI.
Wang W, Nguyen NM, Yablonskiy DA, Sukstanskii AL, Osmanagic E, Atkinson JJ, Conradi MS, Woods JC
Magn Reson Med. 2011 Mar; 65(3)620-6. doi: 10.1002/mrm.22737.

PMID:
    21337400
    [PubMed - indexed for MEDLINE]
Related citations


Diagnostic yield of nasal scrape biopsies in primary ciliary dyskinesia: a multicenter experience.
Olin JT, Burns K, Carson JL, Metjian H, Atkinson JJ, Davis SD, Dell SD, Ferkol TW, Milla CE, Olivier KN, Rosenfeld M, Baker B, Leigh MW, Knowles MR, Sagel SD, Genetic Disorders of Mucociliary Clearance Consortium.
Pediatr Pulmonol. 2011 May; 46(5)483-8. doi: 10.1002/ppul.21402.

PMID:
    21284095
    [PubMed - indexed for MEDLINE]
Related citations


The role of matrix metalloproteinase-9 in cigarette smoke-induced emphysema.
Atkinson JJ, Lutey BA, Suzuki Y, Toennies HM, Kelley DG, Kobayashi DK, Ijem WG, Deslee G, Moore CH, Jacobs ME, Conradi SH, Gierada DS, Pierce RA, Betsuyaku T, Senior RM
Am J Respir Crit Care Med. 2011 Apr 1; 183(7)876-84. doi: 10.1164/rccm.201005-0718OC.

PMID:
    21057003
    [PubMed - indexed for MEDLINE]
Related citations


Measuring small airways in transverse CT images correction for partial volume averaging and airway tilt.
Conradi SH, Lutey BA, Atkinson JJ, Wang W, Senior RM, Gierada DS
Acad Radiol. 2010 Dec; 17(12)1525-34. doi: 10.1016/j.acra.2010.08.005.

PMID:
    20947386
    [PubMed - indexed for MEDLINE]
Related citations


Cigarette smoke induces nucleic-acid oxidation in lung fibroblasts.
Deslee G, Adair-Kirk TL, Betsuyaku T, Woods JC, Moore CH, Gierada DS, Conradi SH, Atkinson JJ, Toennies HM, Battaile JT, Kobayashi DK, Patterson GA, Holtzman MJ, Pierce RA
Am J Respir Cell Mol Biol. 2010 Nov; 43(5)576-84. doi: 10.1165/rcmb.2009-0221OC.

PMID:
    20008282
    [PubMed - indexed for MEDLINE]
Related citations


Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production.
Deshmukh HS, McLachlan A, Atkinson JJ, Hardie WD, Korfhagen TR, Dietsch M, Liu Y, Di PY, Wesselkamper SC, Borchers MT, Leikauf GD
Am J Respir Crit Care Med. 2009 Nov 1; 180(9)834-45. doi: 10.1164/rccm.200903-0328OC.

PMID:
    19661247
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Chronic obstructive pulmonary disease and bronchiectasis