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H. Henry Lai, MD

Associate Professor, Surgery
Division of Urologic Surgery

Specialty Areas

Urologic Surgery
Urology
Female Urology

Board Certifications

Urology
Female Pelvic Medicine and Reconstructive Surgery

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital

Areas of Clinical Interest

Dr. Lai’s areas of expertise include: urodynamics, male and female urinary incontinence, vaginal prolapse (cystocele, rectocele, enterocele, vaginal vault prolapse), overactive bladder, neurogenic bladder, prosthetic surgery, neuromodulation, male and female voiding dysfunction, bladder substitution and urinary diversion, urethral diverticulum, urinary fistula, and interstitial cystitis.

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 11
Office Phone: 314-454-8149
Additional Phone: 314-362-8200
Fax: 314-454-5244

Barnes-Jewish West County Hospital
Medical Building One

1040 N. Mason Road
Creve Coeur, MO 63141

Office Phone: 314-362-8200
Fax: 314-361-2203

Education

Education

Fellowship: Neurourology, Urodynamics and Female Urology, Baylor College of Medicine, Houston, TX 2007
Residency: Baylor College of Medicine, Houston, TX, 2005
Medical Degree: Cornell University Medical College, New York, NY 1999

Publication & Research

Publication & Research

Validation of an Expanded Carrier Screen that Optimizes Sensitivity via Full-Exon Sequencing and Panel-wide Copy Number Variant Identification.
Hogan GJ, Vysotskaia VS, Beauchamp KA, Seisenberger S, Grauman PV, Haas KR, Hong SH, Jeon D, Kash S, Lai HH, Melroy LM, Theilmann MR, Chu CS, Iori K, Maguire JR, Evans EA, Haque IS, Mar-Heyming R, Kang HP, Muzzey D
Clin Chem. 2018 May 14; pii: clinchem.2018.286823. doi: 10.1373/clinchem.2018.286823.

PMID:
    29760218
    [PubMed - as supplied by publisher]
Related citations


Mental Health, Sleep, and Physical Function in Treatment-Seeking Women With Urinary Incontinence.
Siddiqui NY, Wiseman JB, Cella D, Bradley CS, Lai HH, Helmuth ME, Smith AR, Griffith JW, Amundsen CL, Kenton KS, Clemens JQ, Kreder KJ, Merion RM, Kirkali Z, Kusek JW, Cameron AP, Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN).
J Urol. 2018 May 3; pii: S0022-5347(18)43079-0. doi: 10.1016/j.juro.2018.04.076.

PMID:
    29730202
    [PubMed - as supplied by publisher]
Related citations


Bowel function, sexual function, and symptoms of pelvic organ prolapse in women with and without urinary incontinence.
Cameron AP, Smith AR, Lai HH, Bradley CS, Liu AB, Merion RM, Gillespie BW, Amundsen CL, Cella D, Griffith JW, Wiseman JB, Kreder KJ, Kenton KS, Helmuth ME, Fraser MO, Clemens JQ, Kirkali Z, Kusek JW, Siddiqui NY, LURN Study Group.
Neurourol Urodyn. 2018 Apr 10; doi: 10.1002/nau.23587.

PMID:
    29635702
    [PubMed - as supplied by publisher]
Related citations


Prevalence and Characteristics of Urinary Incontinence in a Treatment Seeking Male Prospective Cohort: Results from the LURN Study.
Helfand BT, Smith AR, Lai HH, Yang CC, Gore JL, Erickson BA, Kreder KJ, Cameron AP, Weinfurt KP, Griffith JW, Lentz A, Talaty P, Andreev VP, Kirkali Z, LURN.
J Urol. 2018 Mar 1; pii: S0022-5347(18)39382-0. doi: 10.1016/j.juro.2018.02.075.

PMID:
    29477718
    [PubMed - as supplied by publisher]
Related citations


Research Design Characteristics of Published Pharmacologic Randomized Clinical Trials for Irritable Bowel Syndrome and Chronic Pelvic Pain Conditions: An ACTTION Systematic Review.
Gewandter JS, Chaudari J, Iwan KB, Kitt R, As-Sanie S, Bachmann G, Clemens Q, Lai HH, Tu F, Verne GN, Vincent K, Wesselmann U, Zhou Q, Turk DC, Dworkin RH, Smith SM
J Pain. 2018 Feb 2; pii: S1526-5900(18)30055-5. doi: 10.1016/j.jpain.2018.01.007.

PMID:
    29412183
    [PubMed - as supplied by publisher]
Related citations


Correlates of Health Care Seeking Activities in Patients with Urological Chronic Pelvic Pain Syndromes: Findings from the MAPP Cohort.
Clemens JQ, Stephens-Shields A, Naliboff BD, Lai HH, Rodriguez L, Krieger JN, Williams DA, Kusek JW, Landis JR, MAPP Research Network.
J Urol. 2018 Jan 4; pii: S0022-5347(18)30004-1. doi: 10.1016/j.juro.2017.12.055.

PMID:
    29307682
    [PubMed - as supplied by publisher]
Related citations


A Case-Crossover Study of Urological Chronic Pelvic Pain Syndrome Flare Triggers in the MAPP Research Network.
Sutcliffe S, Jemielita T, Lai HH, Andriole GL, Bradley CS, Clemens JQ, Gallop R, Hooton TM, Kreder KJ, Krieger JN, Kusek JW, Labus J, Lucia MS, Mackey S, Naliboff BD, Robinson NA, Rodriguez LV, Stephens-Shields A, van Bokhoven A, Wolin KY, Yan Y, Yang CC, Landis JR, Colditz GA, MAPP Research Network.
J Urol. 2018 May; 199(5)1245-1251. doi: 10.1016/j.juro.2017.12.050.

PMID:
    29288643
    [PubMed - in process]
Related citations


Use of Euclidean length to measure urinary incontinence severity based on the lower urinary tract symptoms tool.
Helmuth ME, Smith AR, Andreev VP, Liu G, LURN Study Group., Lai HH, Cameron AP, Siddiqui NY
Am J Obstet Gynecol. 2018 Mar; 218(3)357-359. doi: 10.1016/j.ajog.2017.12.219.

PMID:
    29288065
    [PubMed - in process]
Related citations


Weyl-Kondo semimetal in heavy-fermion systems.
Lai HH, Grefe SE, Paschen S, Si Q
Proc Natl Acad Sci U S A. 2018 Jan 2; 115(1)93-97. doi: 10.1073/pnas.1715851115.

PMID:
    29255021
    [PubMed - in process]
Related citations


HIF-1α promotes autophagic proteolysis of Dicer and enhances tumor metastasis.
Lai HH, Li JN, Wang MY, Huang HY, Croce CM, Sun HL, Lyu YJ, Kang JW, Chiu CF, Hung MC, Suzuki HI, Chen PS
J Clin Invest. 2018 Feb 1; 128(2)625-643. doi: 10.1172/JCI89212.

PMID:
    29251629
    [PubMed - in process]
Related citations


Differential expression of immune factor between patients with chronic prostatitis/chronic pelvic pain syndrome and the healthy volunteers.
Ye C, Xiao G, Xu J, Qin S, Luo Y, Chen G, Lai HH, Zhou T
Int Urol Nephrol. 2018 Mar; 50(3)395-399. doi: 10.1007/s11255-017-1763-z.

PMID:
    29235061
    [PubMed - in process]
Related citations


Optogenetic silencing of nociceptive primary afferents reduces evoked and ongoing bladder pain.
Samineni VK, Mickle AD, Yoon J, Grajales-Reyes JG, Pullen MY, Crawford KE, Noh KN, Gereau GB, Vogt SK, Lai HH, Rogers JA, Gereau RW 4th
Sci Rep. 2017 Nov 20; 7(1)15865. doi: 10.1038/s41598-017-16129-3.

PMID:
    29158567
    [PubMed - in process]
Related citations


Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN: A Prospective, Observational Cohort Study.
Cameron AP, Lewicky-Gaupp C, Smith AR, Helfand BT, Gore JL, Clemens JQ, Yang CC, Siddiqui NY, Lai HH, Griffith JW, Andreev VP, Liu G, Weinfurt K, Amundsen CL, Bradley CS, Kusek JW, Kirkali Z, Symptoms of Lower Urinary Tract Dysfunction Research Network Study Group.
J Urol. 2018 Apr; 199(4)1023-1031. doi: 10.1016/j.juro.2017.10.035.

PMID:
    29111381
    [PubMed - in process]
Related citations


Non-invasive electromyographic estimation of motor unit number in the external anal sphincter of the rat.
Zhang C, Munoz A, Lai HH, Boone T, Zhang Y
Neurourol Urodyn. 2018 Jan; 37(1)115-122. doi: 10.1002/nau.23313.

PMID:
    28884835
    [PubMed - in process]
Related citations


Sleep Disturbance and Fatigue Are Associated With More Severe Urinary Incontinence and Overactive Bladder Symptoms.
Ge TJ, Vetter J, Lai HH
Urology. 2017 Nov; 10967-73. doi: 10.1016/j.urology.2017.07.039.

PMID:
    28826875
    [PubMed - in process]
Related citations


Brain signature and functional impact of centralized pain: a multidisciplinary approach to the study of chronic pelvic pain (MAPP) network study.
Kutch JJ, Ichesco E, Hampson JP, Labus JS, Farmer MA, Martucci KT, Ness TJ, Deutsch G, Apkarian AV, Mackey SC, Klumpp DJ, Schaeffer AJ, Rodriguez LV, Kreder KJ, Buchwald D, Andriole GL, Lai HH, Mullins C, Kusek JW, Landis JR, Mayer EA, Clemens JQ, Clauw DJ, Harris RE, MAPP Research Network.
Pain. 2017 Oct; 158(10)1979-1991. doi: 10.1097/j.pain.0000000000001001.

PMID:
    28692006
    [PubMed - indexed for MEDLINE]
Related citations


Anti-vascular endothelial growth factor treatment decreases bladder pain in cyclophosphamide cystitis: a Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network animal model study.
Lai HH, Shen B, Vijairania P, Zhang X, Vogt SK, Gereau RW 4th
BJU Int. 2017 Oct; 120(4)576-583. doi: 10.1111/bju.13924.

PMID:
    28581681
    [PubMed - indexed for MEDLINE]
Related citations


Clinical and Psychosocial Predictors of Urological Chronic Pelvic Pain Symptom Change in 1 Year: A Prospective Study from the MAPP Research Network.
Naliboff BD, Stephens AJ, Lai HH, Griffith JW, Clemens JQ, Lutgendorf S, Rodriguez LV, Newcomb C, Sutcliffe S, Guo W, Kusek JW, Landis JR, MAPP Research Network.
J Urol. 2017 Oct; 198(4)848-857. doi: 10.1016/j.juro.2017.05.065.

PMID:
    28528930
    [PubMed - in process]
Related citations


Antiferroquadrupolar Order and Rotational Symmetry Breaking in a Generalized Bilinear-Biquadratic Model on a Square Lattice.
Lai HH, Hu WJ, Nica EM, Yu R, Si Q
Phys Rev Lett. 2017 Apr 28; 118(17)176401. doi: 10.1103/PhysRevLett.118.176401.

PMID:
    28498700
    [PubMed]
Related citations


Evidence of the Impact of Diet, Fluid Intake, Caffeine, Alcohol and Tobacco on Lower Urinary Tract Symptoms: A Systematic Review.
Bradley CS, Erickson BA, Messersmith EE, Pelletier-Cameron A, Lai HH, Kreder KJ, Yang CC, Merion RM, Bavendam TG, Kirkali Z, Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN).
J Urol. 2017 Nov; 198(5)1010-1020. doi: 10.1016/j.juro.2017.04.097.

PMID:
    28479236
    [PubMed - in process]
Related citations