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H. Henry Lai, MD

Associate Professor, Surgery
Division of Urologic Surgery

Specialty Areas

Urologic Surgery
Urology
Female Urology

Board Certifications

Urology
Female Pelvic Medicine and Reconstructive Surgery

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital

Areas of Clinical Interest

Dr. Lai’s areas of expertise include: urodynamics, male and female urinary incontinence, vaginal prolapse (cystocele, rectocele, enterocele, vaginal vault prolapse), overactive bladder, neurogenic bladder, prosthetic surgery, neuromodulation, male and female voiding dysfunction, bladder substitution and urinary diversion, urethral diverticulum, urinary fistula, and interstitial cystitis.

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 11
Office Phone: 314-454-8149
Additional Phone: 314-362-8200
Fax: 314-454-5244

Barnes-Jewish West County Hospital
Medical Building One

1040 N. Mason Road
Creve Coeur, MO 63141

Office Phone: 314-362-8200
Fax: 314-361-2203

Education

Education

Fellowship: Neurourology, Urodynamics and Female Urology, Baylor College of Medicine, Houston, TX 2007
Residency: Baylor College of Medicine, Houston, TX, 2005
Medical Degree: Cornell University Medical College, New York, NY 1999

Publication & Research

Publication & Research

Research Design Characteristics of Published Pharmacologic Randomized Clinical Trials for Irritable Bowel Syndrome and Chronic Pelvic Pain Conditions: an Acttion Systemic Review.
Gewandter JS, Chaudari J, Iwan KB, Kitt R, As-Sanie S, Bachmann G, Clemens Q, Lai HH, Tu F, Verne GN, Vincent K, Wesselmann U, Zhou Q, Turk DC, Dworkin RH, Smith SM
J Pain. 2018 Feb 2; pii: S1526-5900(18)30055-5. doi: 10.1016/j.jpain.2018.01.007.

PMID:
    29412183
    [PubMed - as supplied by publisher]
Related citations


Correlates of Health-Care Seeking Activities in Patients with Urological Chronic Pelvic Pain Syndromes: Findings from the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Cohort.
Clemens JQ, Stephens-Shields A, Naliboff BD, Lai HH, Rodriguez L, Krieger JN, Williams DA, Kusek JW, Landis JR, MAPP Research Network.
J Urol. 2018 Jan 4; pii: S0022-5347(18)30004-1. doi: 10.1016/j.juro.2017.12.055.

PMID:
    29307682
    [PubMed - as supplied by publisher]
Related citations


A Case-Crossover Study of Urological Chronic Pelvic Pain Syndrome Flare Triggers in the MAPP Research Network.
Sutcliffe S, Jemielita T, Lai HH, Andriole GL, Bradley CS, Clemens JQ, Gallop R, Hooton TM, Kreder KJ, Krieger JN, Kusek JW, Labus J, Lucia MS, Mackey S, Naliboff BD, Robinson NA, Rodriguez LV, Stephens-Shields A, van Bokhoven A, Wolin KY, Yan Y, Yang CC, Landis JR, Colditz GA, MAPP Research Network.
J Urol. 2017 Dec 27; pii: S0022-5347(17)78185-2. doi: 10.1016/j.juro.2017.12.050.

PMID:
    29288643
    [PubMed - as supplied by publisher]
Related citations


Use of Euclidean length to measure urinary incontinence severity based on the lower urinary tract symptoms tool.
Helmuth ME, Smith AR, Andreev VP, Liu G, LURN Study Group., Lai HH, Cameron AP, Siddiqui NY
Am J Obstet Gynecol. 2017 Dec 26; pii: S0002-9378(17)32718-7. doi: 10.1016/j.ajog.2017.12.219.

PMID:
    29288065
    [PubMed - as supplied by publisher]
Related citations


Weyl-Kondo semimetal in heavy-fermion systems.
Lai HH, Grefe SE, Paschen S, Si Q
Proc Natl Acad Sci U S A. 2018 Jan 2; 115(1)93-97. doi: 10.1073/pnas.1715851115.

PMID:
    29255021
    [PubMed - in process]
Related citations


HIF-1α promotes autophagic proteolysis of Dicer and enhances tumor metastasis.
Lai HH, Li JN, Wang MY, Huang HY, Croce CM, Sun HL, Lyu YJ, Kang JW, Chiu CF, Hung MC, Suzuki HI, Chen PS
J Clin Invest. 2018 Feb 1; 128(2)625-643. doi: 10.1172/JCI89212.

PMID:
    29251629
    [PubMed - in process]
Related citations


Differential expression of immune factor between patients with chronic prostatitis/chronic pelvic pain syndrome and the healthy volunteers.
Ye C, Xiao G, Xu J, Qin S, Luo Y, Chen G, Lai HH, Zhou T
Int Urol Nephrol. 2017 Dec 12; doi: 10.1007/s11255-017-1763-z.

PMID:
    29235061
    [PubMed - as supplied by publisher]
Related citations


Optogenetic silencing of nociceptive primary afferents reduces evoked and ongoing bladder pain.
Samineni VK, Mickle AD, Yoon J, Grajales-Reyes JG, Pullen MY, Crawford KE, Noh KN, Gereau GB, Vogt SK, Lai HH, Rogers JA, Gereau RW 4th
Sci Rep. 2017 Nov 20; 7(1)15865. doi: 10.1038/s41598-017-16129-3.

PMID:
    29158567
    [PubMed - in process]
Related citations


Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN: A Prospective, Observational Cohort Study.
Cameron AP, Lewicky-Gaupp C, Smith AR, Helfand BT, Gore JL, Clemens JQ, Yang CC, Siddiqui NY, Lai HH, Griffith JW, Andreev VP, Liu G, Weinfurt K, Amundsen CL, Bradley CS, Kusek JW, Kirkali Z, Symptoms of Lower Urinary Tract Dysfunction Research Network Study Group.
J Urol. 2017 Oct 28; pii: S0022-5347(17)77802-0. doi: 10.1016/j.juro.2017.10.035.

PMID:
    29111381
    [PubMed - as supplied by publisher]
Related citations


Non-invasive electromyographic estimation of motor unit number in the external anal sphincter of the rat.
Zhang C, Munoz A, Lai HH, Boone T, Zhang Y
Neurourol Urodyn. 2018 Jan; 37(1)115-122. doi: 10.1002/nau.23313.

PMID:
    28884835
    [PubMed - in process]
Related citations


Sleep Disturbance and Fatigue Are Associated With More Severe Urinary Incontinence and Overactive Bladder Symptoms.
Ge TJ, Vetter J, Lai HH
Urology. 2017 Nov; 10967-73. doi: 10.1016/j.urology.2017.07.039.

PMID:
    28826875
    [PubMed - in process]
Related citations


Brain signature and functional impact of centralized pain: a multidisciplinary approach to the study of chronic pelvic pain (MAPP) network study.
Kutch JJ, Ichesco E, Hampson JP, Labus JS, Farmer MA, Martucci KT, Ness TJ, Deutsch G, Apkarian AV, Mackey SC, Klumpp DJ, Schaeffer AJ, Rodriguez LV, Kreder KJ, Buchwald D, Andriole GL, Lai HH, Mullins C, Kusek JW, Landis JR, Mayer EA, Clemens JQ, Clauw DJ, Harris RE, MAPP Research Network.
Pain. 2017 Oct; 158(10)1979-1991. doi: 10.1097/j.pain.0000000000001001.

PMID:
    28692006
    [PubMed - in process]
Related citations


Anti-vascular endothelial growth factor treatment decreases bladder pain in cyclophosphamide cystitis: a Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network animal model study.
Lai HH, Shen B, Vijairania P, Zhang X, Vogt SK, Gereau RW 4th
BJU Int. 2017 Oct; 120(4)576-583. doi: 10.1111/bju.13924.

PMID:
    28581681
    [PubMed - indexed for MEDLINE]
Related citations


Clinical and Psychosocial Predictors of Urological Chronic Pelvic Pain Symptom Change in 1 Year: A Prospective Study from the MAPP Research Network.
Naliboff BD, Stephens AJ, Lai HH, Griffith JW, Clemens JQ, Lutgendorf S, Rodriguez LV, Newcomb C, Sutcliffe S, Guo W, Kusek JW, Landis JR, MAPP Research Network.
J Urol. 2017 Oct; 198(4)848-857. doi: 10.1016/j.juro.2017.05.065.

PMID:
    28528930
    [PubMed - in process]
Related citations


Antiferroquadrupolar Order and Rotational Symmetry Breaking in a Generalized Bilinear-Biquadratic Model on a Square Lattice.
Lai HH, Hu WJ, Nica EM, Yu R, Si Q
Phys Rev Lett. 2017 Apr 28; 118(17)176401. doi: 10.1103/PhysRevLett.118.176401.

PMID:
    28498700
    [PubMed]
Related citations


Evidence of the Impact of Diet, Fluid Intake, Caffeine, Alcohol and Tobacco on Lower Urinary Tract Symptoms: A Systematic Review.
Bradley CS, Erickson BA, Messersmith EE, Pelletier-Cameron A, Lai HH, Kreder KJ, Yang CC, Merion RM, Bavendam TG, Kirkali Z, Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN).
J Urol. 2017 Nov; 198(5)1010-1020. doi: 10.1016/j.juro.2017.04.097.

PMID:
    28479236
    [PubMed - in process]
Related citations


Identification of mosaic and segmental aneuploidies by next-generation sequencing in preimplantation genetic screening can improve clinical outcomes compared to array-comparative genomic hybridization.
Lai HH, Chuang TH, Wong LK, Lee MJ, Hsieh CL, Wang HL, Chen SU
Mol Cytogenet. 2017; 1014. doi: 10.1186/s13039-017-0315-7.

PMID:
    28450889
    [PubMed]
Related citations


Characterization of Whole Body Pain in Urological Chronic Pelvic Pain Syndrome at Baseline: A MAPP Research Network Study.
Lai HH, Jemielita T, Sutcliffe S, Bradley CS, Naliboff B, Williams DA, Gereau RW 4th, Kreder K, Clemens JQ, Rodriguez LV, Krieger JN, Farrar JT, Robinson N, Landis JR, MAPP Research Network.
J Urol. 2017 Sep; 198(3)622-631. doi: 10.1016/j.juro.2017.03.132.

PMID:
    28373134
    [PubMed - in process]
Related citations


Development and validation of a 36-gene sequencing assay for hereditary cancer risk assessment.
Vysotskaia VS, Hogan GJ, Gould GM, Wang X, Robertson AD, Haas KR, Theilmann MR, Spurka L, Grauman PV, Lai HH, Jeon D, Haliburton G, Leggett M, Chu CS, Iori K, Maguire JR, Ready K, Evans EA, Kang HP, Haque IS
PeerJ. 2017; 5e3046. doi: 10.7717/peerj.3046.

PMID:
    28243543
    [PubMed]
Related citations


Association of Body Mass Index with Timing of Death during Tuberculosis Treatment.
Lai HH, Lai YJ, Yen YF
PLoS One. 2017; 12(1)e0170104. doi: 10.1371/journal.pone.0170104.

PMID:
    28085951
    [PubMed - indexed for MEDLINE]
Related citations