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Gregory J. Zipfel, MD

Professor, Neurosurgery
Professor, Neurology

Specialty Areas

Cerebrovascular Disease
Brain Tumors
Skull Base Tumors
Aneurysms and Vascular Malformations
Stroke
Carotid Disease
Pituitary Tumors
Moyamoya Disease
Neuro Oncology
Neurovascular Disorders
Aneurysms
Arteriovenus Malformation
Gamma Knife
Neurosurgery

Board Certifications

Neurological Surgery

Hospital Affiliations

St. Louis Children's Hospital
Barnes-Jewish Hospital

Areas of Clinical Interest

Cerebrovascular disease including aneurysms, arteriovenous malformations, cavernous malformations, carotid stenosis, Moyamoya disease and arterial bypass surgery, skull base tumors including meningiomas, acoustic neuromas, craniofacial tumors and pituitary brain tumors, Pituitary Center

  • Maps & Directions
  • Education
  • Publication & Research
  • Videos

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Neuroscience Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: 314-362-3577
Fax: 314-362-2107

Center for Advanced Medicine - South County

5201 Midamerica Plaza
St. Louis, MO 63129

Office Phone: 314-362-3577
Fax: 314-362-2107

Education

Education

Fellowship: Neurological Surgery, University of Miami, Miami, Florida 2003
Residency: Neurological Surgery, University of Miami, Gainesville, Florida 2003
Medical Degree: Northwestern University Medical School, Chicago, Illinois 1995
B.S.: Biology, University of Illinois College of Liberal Arts and Sciences, Champaign-Urbana, Illinois 1991

Publication & Research

Publication & Research

In Reply: Neurosurgical Education in a Changing Healthcare and Regulatory Environment: A Consensus Statement From 6 Programs.
Kim DH, Dacey RG, Zipfel GJ, Berger MS, McDermott M, Barbaro NM, Shapiro SA, Solomon RA, Harbaugh R, Day AL
Neurosurgery. 2017 Oct 1; 81(4)E47. doi: 10.1093/neuros/nyx348.

PMID:
    28934443
    [PubMed - in process]
Related citations


A Randomized Trial of Brief Versus Extended Seizure Prophylaxis After Aneurysmal Subarachnoid Hemorrhage.
Human T, Diringer MN, Allen M, Zipfel GJ, Chicoine M, Dacey R, Dhar R
Neurocrit Care. 2017 Aug 22; doi: 10.1007/s12028-017-0440-5.

PMID:
    28831717
    [PubMed - as supplied by publisher]
Related citations


A novel fluorescent imaging technique for assessment of cerebral vasospasm after experimental subarachnoid hemorrhage.
Aum DJ, Vellimana AK, Singh I, Milner E, Nelson JW, Han BH, Zipfel GJ
Sci Rep. 2017 Aug 22; 7(1)9126. doi: 10.1038/s41598-017-09070-y.

PMID:
    28831103
    [PubMed - in process]
Related citations


Minimal Long-Term Neurobehavioral Impairments after Endovascular Perforation Subarachnoid Hemorrhage in Mice.
Fanizzi C, Sauerbeck AD, Gangolli M, Zipfel GJ, Brody DL, Kummer TT
Sci Rep. 2017 Aug 8; 7(1)7569. doi: 10.1038/s41598-017-07701-y.

PMID:
    28790425
    [PubMed - in process]
Related citations


Management of Brain Arteriovenous Malformations: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association.
Derdeyn CP, Zipfel GJ, Albuquerque FC, Cooke DL, Feldmann E, Sheehan JP, Torner JC, American Heart Association Stroke Council.
Stroke. 2017 Aug; 48(8)e200-e224. doi: 10.1161/STR.0000000000000134.

PMID:
    28642352
    [PubMed - indexed for MEDLINE]
Related citations


Intracranial Dural Arteriovenous Fistulae.
Reynolds MR, Lanzino G, Zipfel GJ
Stroke. 2017 May; 48(5)1424-1431. doi: 10.1161/STROKEAHA.116.012784.

PMID:
    28432263
    [PubMed - in process]
Related citations


Baseline Hemodynamic Impairment and Future Stroke Risk in Adult Idiopathic Moyamoya Phenomenon: Results of a Prospective Natural History Study.
Derdeyn CP, Zipfel GJ, Zazulia AR, Davis PH, Prabhakaran S, Ivan CS, Aiyagari V, Sagar JR, Hantler N, Shinawi L, Lee JJ, Jafri H, Grubb RL Jr, Miller JP, Dacey RG Jr
Stroke. 2017 Apr; 48(4)894-899. doi: 10.1161/STROKEAHA.116.014538.

PMID:
    28283605
    [PubMed - indexed for MEDLINE]
Related citations


Comparing External Ventricular Drains-Related Ventriculitis Surveillance Definitions.
Reyes MM, Munigala S, Church EL, Kulik TB, Keyrouz SG, Zipfel GJ, Warren DK
Infect Control Hosp Epidemiol. 2017 May; 38(5)574-579. doi: 10.1017/ice.2017.21.

PMID:
    28219470
    [PubMed - in process]
Related citations


Neurosurgical Education in a Changing Healthcare and Regulatory Environment: A Consensus Statement from 6 Programs.
Kim DH, Dacey RG, Zipfel GJ, Berger MS, McDermott M, Barbaro NM, Shapiro SA, Solomon RA, Harbaugh R, Day AL
Neurosurgery. 2017 Apr 1; 80(4S)S75-S82. doi: 10.1093/neuros/nyw146.

PMID:
    28204661
    [PubMed - indexed for MEDLINE]
Related citations


Higher Stroke Risk with Lower Blood Pressure in Hemodynamic Vertebrobasilar Disease: Analysis from the VERiTAS Study.
Amin-Hanjani S, Turan TN, Du X, Pandey DK, Rose-Finnell L, Richardson D, Elkind MS, Zipfel GJ, Liebeskind DS, Silver FL, Kasner SE, Gorelick PB, Charbel FT, Derdeyn CP, VERiTAS Study Group.
J Stroke Cerebrovasc Dis. 2017 Feb; 26(2)403-410. doi: 10.1016/j.jstrokecerebrovasdis.2016.09.044.

PMID:
    28029608
    [PubMed - indexed for MEDLINE]
Related citations


The relationship of cortical folding and brain arteriovenous malformations.
Shah MN, Smith SE, Dierker DL, Herbert JP, Coalson TS, Bruck BS, Zipfel GJ, Van Essen DC, Dacey RG Jr
Neurovasc Imaging. 2016; 2pii: 13. doi: 10.1186/s40809-016-0024-3.

PMID:
    28009020
    [PubMed]
Related citations


Double Monoclonal Immunoassay for Quantifying Human Visinin-Like Protein-1 in CSF.
Crimmins DL, Herries EM, Ohlendorf MF, Brada NA, Garbett NC, Zipfel GJ, Schindler SE, Ladenson JH
Clin Chem. 2017 Feb; 63(2)603-604. doi: 10.1373/clinchem.2016.263236.

PMID:
    27986783
    [PubMed - in process]
Related citations


Endovascular management of internal carotid artery injuries secondary to endonasal surgery: case series and review of the literature.
Sylvester PT, Moran CJ, Derdeyn CP, Cross DT, Dacey RG, Zipfel GJ, Kim AH, Uppaluri R, Haughey BH, Tempelhoff R, Rich KM, Schneider J, Chole RA, Chicoine MR
J Neurosurg. 2016 Nov; 125(5)1256-1276.

PMID:
    26771847
    [PubMed - in process]
Related citations


Predictors of 30-day readmission after aneurysmal subarachnoid hemorrhage: a case-control study.
Greenberg JK, Guniganti R, Arias EJ, Desai K, Washington CW, Yan Y, Weng H, Xiong C, Fondahn E, Cross DT, Moran CJ, Rich KM, Chicoine MR, Dhar R, Dacey RG Jr, Derdeyn CP, Zipfel GJ
J Neurosurg. 2017 Jun; 126(6)1847-1854. doi: 10.3171/2016.5.JNS152644.

PMID:
    27494820
    [PubMed - in process]
Related citations


Endovascular parent vessel sacrifice in ruptured dissecting vertebral and posterior inferior cerebellar artery aneurysms: clinical outcomes and review of the literature.
Madaelil TP, Wallace AN, Chatterjee AN, Zipfel GJ, Dacey RG Jr, Cross DT 3rd, Moran CJ, Derdeyn CP
J Neurointerv Surg. 2016 Aug; 8(8)796-801. doi: 10.1136/neurintsurg-2015-011732.

PMID:
    27417905
    [PubMed - indexed for MEDLINE]
Related citations


Spontaneous Subarachnoid Hemorrhage: A Systematic Review and Meta-analysis Describing the Diagnostic Accuracy of History, Physical Examination, Imaging, and Lumbar Puncture With an Exploration of Test Thresholds.
Carpenter CR, Hussain AM, Ward MJ, Zipfel GJ, Fowler S, Pines JM, Sivilotti ML
Acad Emerg Med. 2016 Sep; 23(9)963-1003. doi: 10.1111/acem.12984.

PMID:
    27306497
    [PubMed - indexed for MEDLINE]
Related citations


Diagnostic and Prognostic Utility of the Synaptic Marker Neurogranin in Alzheimer Disease.
Tarawneh R, D'Angelo G, Crimmins D, Herries E, Griest T, Fagan AM, Zipfel GJ, Ladenson JH, Morris JC, Holtzman DM
JAMA Neurol. 2016 May 1; 73(5)561-71. doi: 10.1001/jamaneurol.2016.0086.

PMID:
    27018940
    [PubMed - indexed for MEDLINE]
Related citations


Heparan sulfate proteoglycans mediate Aβ-induced oxidative stress and hypercontractility in cultured vascular smooth muscle cells.
Reynolds MR, Singh I, Azad TD, Holmes BB, Verghese PB, Dietrich HH, Diamond M, Bu G, Han BH, Zipfel GJ
Mol Neurodegener. 2016 Jan 22; 119. doi: 10.1186/s13024-016-0073-8.

PMID:
    26801396
    [PubMed - indexed for MEDLINE]
Related citations


Effect of Hemodynamics on Stroke Risk in Symptomatic Atherosclerotic Vertebrobasilar Occlusive Disease.
Amin-Hanjani S, Pandey DK, Rose-Finnell L, Du X, Richardson D, Thulborn KR, Elkind MS, Zipfel GJ, Liebeskind DS, Silver FL, Kasner SE, Aletich VA, Caplan LR, Derdeyn CP, Gorelick PB, Charbel FT, Vertebrobasilar Flow Evaluation and Risk of Transient Ischemic Attack and Stroke Study Group.
JAMA Neurol. 2016 Feb; 73(2)178-85. doi: 10.1001/jamaneurol.2015.3772.

PMID:
    26720181
    [PubMed - indexed for MEDLINE]
Related citations


Radiation Therapy for Residual or Recurrent Atypical Meningioma: The Effects of Modality, Timing, and Tumor Pathology on Long-Term Outcomes.
Sun SQ, Cai C, Murphy RK, DeWees T, Dacey RG, Grubb RL, Rich KM, Zipfel GJ, Dowling JL, Leuthardt EC, Simpson JR, Robinson CG, Chicoine MR, Perrin RJ, Huang J, Kim AH
Neurosurgery. 2016 Jul; 79(1)23-32. doi: 10.1227/NEU.0000000000001160.

PMID:
    26645969
    [PubMed - in process]
Related citations

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