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Gregory A. Ewald, MD

Professor, Medicine
Division of Cardiovascular Diseases
Chief of Clinical Cardiology
Director, Section of Heart Failure and Heart Transplantation
Medical Director, Cardiac Transplant Program, Barnes-Jewish Hospital
Medical Director, Mid-America Transplant Service

Specialty Areas

Cardiology
Heart Failure / Transplant
Congestive Heart Failure

Board Certifications

Cardiovascular Disease

Hospital Affiliations

Barnes-Jewish Hospital
Freeman Hospital - Joplin

Areas of Clinical Interest

Congestive heart failure, CHF, cardiac transplant, acute myocardial infarction, pulmonary hypertension, high blood pressure, cardiomyopathy, coronary heart disease, heart attack, endocarditis, angina pectoris

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Barnes-Jewish West County Hospital
Medical Building Three

1020 N. Mason Road
St. Louis, MO 63141

Office Phone: 314-362-1291

Freeman Heart Clinic

1102 W. 32nd Street
Joplin, MO 64804

Office Phone: 314-362-1291
Additional Phone: 888-210-8375

Center for Advanced Medicine
Heart & Vascular Center

4921 Parkview Place
St. Louis, MO 63110

Suite: A
Floor: 8
Office Phone: 314-362-1291
Fax: 314-362-2512

Education

Education

Clinical Fellowship: Cardiology , Washington University School of Medicine, St. Louis, Missouri 1997
Chief Residency: Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 1995
Research Fellow: Cardiology, Washington University School of Medicine, St. Louis, MO 1994
Residency: Internal Medicine, Barnes Hospital at Washington University School of Medicine, St. Louis, Missouri 1992
Medical Degree: Northwestern University, Chicago, Illinois 1989
B.S.: Biology, University of Illinois, Urbana-Champaign, Illinois 1985

Publication & Research

Publication & Research

Hemocompatibility-Related Outcomes in the MOMENTUM 3 Trial at 6 Months: A Randomized Controlled Study of a Fully Magnetically Levitated Pump in Advanced Heart Failure.
Uriel N, Colombo PC, Cleveland JC, Long JW, Salerno C, Goldstein DJ, Patel CB, Ewald GA, Tatooles AJ, Silvestry SC, John R, Caldeira C, Jeevanandam V, Boyle AJ, Sundareswaran KS, Sood P, Mehra MR
Circulation. 2017 May 23; 135(21)2003-2012. doi: 10.1161/CIRCULATIONAHA.117.028303.

PMID:
    28385948
    [PubMed - in process]
Related citations


Left Ventricular Unloading by Impella Device Versus Surgical Vent During Extracorporeal Life Support.
Tepper S, Masood MF, Baltazar Garcia M, Pisani M, Ewald GA, Lasala JM, Bach RG, Singh J, Balsara KR, Itoh A
Ann Thorac Surg. 2017 Mar 24; pii: S0003-4975(17)30039-5. doi: 10.1016/j.athoracsur.2016.12.049.

PMID:
    28347536
    [PubMed - as supplied by publisher]
Related citations


Global Outcome in Patients With Left Ventricular Assist Devices.
Fendler TJ, Nassif ME, Kennedy KF, Joseph SM, Silvestry SC, Ewald GA, LaRue SJ, Vader JM, Spertus JA, Arnold SV
Am J Cardiol. 2017 Apr 1; 119(7)1069-1073. doi: 10.1016/j.amjcard.2016.12.014.

PMID:
    28160976
    [PubMed - indexed for MEDLINE]
Related citations


A Fully Magnetically Levitated Circulatory Pump for Advanced Heart Failure.
Mehra MR, Naka Y, Uriel N, Goldstein DJ, Cleveland JC Jr, Colombo PC, Walsh MN, Milano CA, Patel CB, Jorde UP, Pagani FD, Aaronson KD, Dean DA, McCants K, Itoh A, Ewald GA, Horstmanshof D, Long JW, Salerno C, MOMENTUM 3 Investigators.
N Engl J Med. 2017 Feb 2; 376(5)440-450. doi: 10.1056/NEJMoa1610426.

PMID:
    27959709
    [PubMed - indexed for MEDLINE]
Related citations


Use of adenosine diphosphate receptor inhibitor prior to left ventricular assist device implantation is not associated with increased bleeding.
Tibrewala A, Nassif ME, Andruska A, Shuster JE, Novak E, Vader JM, Ewald GA, LaRue SJ, Silvestry S, Itoh A
J Artif Organs. 2017 Mar; 20(1)42-49. doi: 10.1007/s10047-016-0932-7.

PMID:
    27830349
    [PubMed - indexed for MEDLINE]
Related citations


Left Ventricular Assist Device Inflow Angle and Pump Positional Change Over Time Adverse Impact on Left Ventricular Assist Device Function.
Kazui T, Zhang A, Greenberg J, Itoh A, Tran PL, Keith AD, Ewald GA, Damiano RJ Jr, Silvestry SC
Ann Thorac Surg. 2016 Dec; 102(6)1933-1940. doi: 10.1016/j.athoracsur.2016.05.025.

PMID:
    27469340
    [PubMed - indexed for MEDLINE]
Related citations


A Case Series of Acute Myocardial Infarction in Left Ventricular Assist Device-Supported Patients.
Godishala A, Nassif ME, Raymer DS, Hartupee J, Ewald GA, Larue SJ, Vader JM
ASAIO J. 2017 Mar/Apr; 63(2)e18-e24. doi: 10.1097/MAT.0000000000000401.

PMID:
    27258219
    [PubMed - in process]
Related citations


Relationship Between Anticoagulation Intensity and Thrombotic or Bleeding Outcomes Among Outpatients With Continuous-Flow Left Ventricular Assist Devices.
Nassif ME, LaRue SJ, Raymer DS, Novak E, Vader JM, Ewald GA, Gage BF
Circ Heart Fail. 2016 May; 9(5)pii: e002680. doi: 10.1161/CIRCHEARTFAILURE.115.002680.

PMID:
    27154497
    [PubMed - indexed for MEDLINE]
Related citations


Mitochondrial structure and function are not different between nonfailing donor and end-stage failing human hearts.
Holzem KM, Vinnakota KC, Ravikumar VK, Madden EJ, Ewald GA, Dikranian K, Beard DA, Efimov IR
FASEB J. 2016 Aug; 30(8)2698-707. doi: 10.1096/fj.201500118R.

PMID:
    27075244
    [PubMed - in process]
Related citations


The HVAD Left Ventricular Assist Device: Risk Factors for Neurological Events and Risk Mitigation Strategies.
Teuteberg JJ, Slaughter MS, Rogers JG, McGee EC, Pagani FD, Gordon R, Rame E, Acker M, Kormos RL, Salerno C, Schleeter TP, Goldstein DJ, Shin J, Starling RC, Wozniak T, Malik AS, Silvestry S, Ewald GA, Jorde UP, Naka Y, Birks E, Najarian KB, Hathaway DR, Aaronson KD, ADVANCE Trial Investigators.
JACC Heart Fail. 2015 Oct; 3(10)818-28. doi: 10.1016/j.jchf.2015.05.011.

PMID:
    26450000
    [PubMed - indexed for MEDLINE]
Related citations


Reduced response to IKr blockade and altered hERG1a/1b stoichiometry in human heart failure.
Holzem KM, Gomez JF, Glukhov AV, Madden EJ, Koppel AC, Ewald GA, Trenor B, Efimov IR
J Mol Cell Cardiol. 2016 Jul; 9682-92. doi: 10.1016/j.yjmcc.2015.06.008.

PMID:
    26093152
    [PubMed - indexed for MEDLINE]
Related citations


Heart Failure in Non-Caucasians, Women, and Older Adults: A White Paper on Special Populations From the Heart Failure Society of America Guideline Committee.
Colvin M, Sweitzer NK, Albert NM, Krishnamani R, Rich MW, Stough WG, Walsh MN, Westlake Canary CA, Allen LA, Bonnell MR, Carson PE, Chan MC, Dickinson MG, Dries DL, Ewald GA, Fang JC, Hernandez AF, Hershberger RE, Katz SD, Moore S, Rodgers JE, Rogers JG, Vest AR, Whellan DJ, Givertz MM
J Card Fail. 2015 Aug; 21(8)674-93. doi: 10.1016/j.cardfail.2015.05.013.

PMID:
    26051012
    [PubMed - indexed for MEDLINE]
Related citations


Advanced (stage D) heart failure: a statement from the Heart Failure Society of America Guidelines Committee.
Fang JC, Ewald GA, Allen LA, Butler J, Westlake Canary CA, Colvin-Adams M, Dickinson MG, Levy P, Stough WG, Sweitzer NK, Teerlink JR, Whellan DJ, Albert NM, Krishnamani R, Rich MW, Walsh MN, Bonnell MR, Carson PE, Chan MC, Dries DL, Hernandez AF, Hershberger RE, Katz SD, Moore S, Rodgers JE, Rogers JG, Vest AR, Givertz MM, Heart Failure Society of America Guidelines Committee.
J Card Fail. 2015 Jun; 21(6)519-34. doi: 10.1016/j.cardfail.2015.04.013.

PMID:
    25953697
    [PubMed - indexed for MEDLINE]
Related citations


Gene expression profiling to study racial differences after heart transplantation.
Khush KK, Pham MX, Teuteberg JJ, Kfoury AG, Deng MC, Kao A, Anderson AS, Cotts WG, Ewald GA, Baran DA, Hiller D, Yee J, Valantine HA
J Heart Lung Transplant. 2015 Jul; 34(7)970-7. doi: 10.1016/j.healun.2015.01.987.

PMID:
    25840504
    [PubMed - indexed for MEDLINE]
Related citations


The Heartmate Risk Score predicts morbidity and mortality in unselected left ventricular assist device recipients and risk stratifies INTERMACS class 1 patients.
Adamo L, Nassif M, Tibrewala A, Novak E, Vader J, Silvestry SC, Itoh A, Ewald GA, Mann DL, LaRue SJ
JACC Heart Fail. 2015 Apr; 3(4)283-90. doi: 10.1016/j.jchf.2014.11.005.

PMID:
    25770410
    [PubMed - indexed for MEDLINE]
Related citations


Treatment of secondary pulmonary hypertension with bosentan after left ventricular assist device implantation.
LaRue SJ, Garcia-Cortes R, Nassif ME, Vader JM, Ray S, Ravichandran A, Rasalingham R, Silvestry SC, Ewald GA, Wang IW, Schilling JD
Cardiovasc Ther. 2015 Apr; 33(2)50-5. doi: 10.1111/1755-5922.12111.

PMID:
    25759010
    [PubMed - indexed for MEDLINE]
Related citations


Reduction in driveline infection rates: Results from the HeartMate II Multicenter Driveline Silicone Skin Interface (SSI) Registry.
Dean D, Kallel F, Ewald GA, Tatooles A, Sheridan BC, Brewer RJ, Caldeira C, Farrar DJ, Akhter SA, SSI Registry Investigators.
J Heart Lung Transplant. 2015 Jun; 34(6)781-9. doi: 10.1016/j.healun.2014.11.021.

PMID:
    25735901
    [PubMed - indexed for MEDLINE]
Related citations


Arrhythmogenic remodeling of β2 versus β1 adrenergic signaling in the human failing heart.
Lang D, Holzem K, Kang C, Xiao M, Hwang HJ, Ewald GA, Yamada KA, Efimov IR
Circ Arrhythm Electrophysiol. 2015 Apr; 8(2)409-19. doi: 10.1161/CIRCEP.114.002065.

PMID:
    25673629
    [PubMed - indexed for MEDLINE]
Related citations


Clinical outcomes with use of erythropoiesis stimulating agents in patients with the HeartMate II left ventricular assist device.
Nassif ME, Patel JS, Shuster JE, Raymer DS, Jackups R Jr, Novak E, Gage BF, Prasad S, Silvestry SC, Ewald GA, LaRue SJ
JACC Heart Fail. 2015 Feb; 3(2)146-53. doi: 10.1016/j.jchf.2014.08.005.

PMID:
    25660839
    [PubMed - indexed for MEDLINE]
Related citations


Systolic blood pressure on discharge after left ventricular assist device insertion is associated with subsequent stroke.
Nassif ME, Tibrewala A, Raymer DS, Andruska A, Novak E, Vader JM, Itoh A, Silvestry SC, Ewald GA, LaRue SJ
J Heart Lung Transplant. 2015 Apr; 34(4)503-8. doi: 10.1016/j.healun.2014.09.042.

PMID:
    25540881
    [PubMed - indexed for MEDLINE]
Related citations