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Faculty Physicians

Glenn Lopate, MD

Associate Professor, Neurology
Division of Adult Neurology and Neuromuscular Disease

Specialty Areas

Neuromuscular Disease
Nerve Disorders
Neurology - Adult
Muscle Disorders
Muscular Dystrophy
ALS - Lou Gehrig's Disease
Myasthenia Gravis
Electromyography

Board Certifications

Electrodiagnostic Medicine
Neurology

Areas of Clinical Interest

Neuromuscular diseases, electromyography, post-paralysis paralysis (PPP) syndrome, motor neuropathy syndromes, polyneuropathy syndromes, autoimmune myasthenia gravis, chronic immune demyelinating neuropathies, immune neuropathies, muscular dystrophies, immune myopathies, ALS-Lou Gehrig’s disease

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Neuroscience Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: 314-362-6981
Fax: 314-362-3752

Education

Education

Fellowship: Neuromuscular Disease, Washington University School of Medicine, St. Louis, Missouri 1994
Residency: Neurology, Washington University School of Medicine, St. Louis, Missouri 1991
Medical Degree: Ohio State University College of Medicine, Columbus, Ohio 1987
B.S.: Zoology, Colorado State University, Fort Collins, Colorado 1983

Publication & Research

Publication & Research

Myovascular innervation: axon loss in small-fiber neuropathies.
Dori A, Lopate G, Keeling R, Pestronk A
Muscle Nerve. 2015 Apr; 51(4)514-21. doi: 10.1002/mus.24356.

PMID:
    25091433
    [PubMed - indexed for MEDLINE]
Related citations


Ataluren treatment of patients with nonsense mutation dystrophinopathy.
Bushby K, Finkel R, Wong B, Barohn R, Campbell C, Comi GP, Connolly AM, Day JW, Flanigan KM, Goemans N, Jones KJ, Mercuri E, Quinlivan R, Renfroe JB, Russman B, Ryan MM, Tulinius M, Voit T, Moore SA, Lee Sweeney H, Abresch RT, Coleman KL, Eagle M, Florence J, Gappmaier E, Glanzman AM, Henricson E, Barth J, Elfring GL, Reha A, Spiegel RJ, O'donnell MW, Peltz SW, Mcdonald CM, PTC124-GD-007-DMD STUDY GROUP
Muscle Nerve. 2014 Oct; 50(4)477-87. doi: 10.1002/mus.24332.

PMID:
    25042182
    [PubMed - indexed for MEDLINE]
Related citations


A controlled trial of intravenous immunoglobulin in multifocal motor neuropathy.
Hahn AF, Beydoun SR, Lawson V, IVIG in MMN Study Team, Oh M, Empson VG, Leibl H, Ngo LY, Gelmont D, Koski CL
J Peripher Nerv Syst. 2013 Dec; 18(4)321-30. doi: 10.1111/jns5.12046.

PMID:
    24725024
    [PubMed - indexed for MEDLINE]
Related citations


Cooperative International Neuromuscular Research Group Duchenne Natural History Study demonstrates insufficient diagnosis and treatment of cardiomyopathy in Duchenne muscular dystrophy.
Spurney C, Shimizu R, Morgenroth LP, Kolski H, Gordish-Dressman H, Clemens PR, CINRG Investigators
Muscle Nerve. 2014 Aug; 50(2)250-6. doi: 10.1002/mus.24163.

PMID:
    24395289
    [PubMed - indexed for MEDLINE]
Related citations


Cramps and small-fiber neuropathy.
Lopate G, Streif E, Harms M, Weihl C, Pestronk A
Muscle Nerve. 2013 Aug; 48(2)252-5. doi: 10.1002/mus.23757.

PMID:
    23813593
    [PubMed - indexed for MEDLINE]
Related citations


The cooperative international neuromuscular research group Duchenne natural history study--a longitudinal investigation in the era of glucocorticoid therapy: design of protocol and the methods used.
McDonald CM, Henricson EK, Abresch RT, Han JJ, Escolar DM, Florence JM, Duong T, Arrieta A, Clemens PR, Hoffman EP, Cnaan A, Cinrg Investigators
Muscle Nerve. 2013 Jul; 48(1)32-54. doi: 10.1002/mus.23807.

PMID:
    23677550
    [PubMed - indexed for MEDLINE]
Related citations


The cooperative international neuromuscular research group Duchenne natural history study: glucocorticoid treatment preserves clinically meaningful functional milestones and reduces rate of disease progression as measured by manual muscle testing and other commonly used clinical trial outcome measures.
Henricson EK, Abresch RT, Cnaan A, Hu F, Duong T, Arrieta A, Han J, Escolar DM, Florence JM, Clemens PR, Hoffman EP, McDonald CM, CINRG Investigators
Muscle Nerve. 2013 Jul; 48(1)55-67. doi: 10.1002/mus.23808.

PMID:
    23649481
    [PubMed - indexed for MEDLINE]
Related citations


LTBP4 genotype predicts age of ambulatory loss in Duchenne muscular dystrophy.
Flanigan KM, Ceco E, Lamar KM, Kaminoh Y, Dunn DM, Mendell JR, King WM, Pestronk A, Florence JM, Mathews KD, Finkel RS, Swoboda KJ, Gappmaier E, Howard MT, Day JW, McDonald C, McNally EM, Weiss RB, United Dystrophinopathy Project
Ann Neurol. 2013 Apr; 73(4)481-8. doi: 10.1002/ana.23819.

PMID:
    23440719
    [PubMed - indexed for MEDLINE]
Related citations


Exome sequencing reveals DNAJB6 mutations in dominantly-inherited myopathy.
Harms MB, Sommerville RB, Allred P, Bell S, Ma D, Cooper P, Lopate G, Pestronk A, Weihl CC, Baloh RH
Ann Neurol. 2012 Mar; 71(3)407-16. doi: 10.1002/ana.22683.

PMID:
    22334415
    [PubMed - indexed for MEDLINE]
Related citations


Familial ALS with extreme phenotypic variability due to the I113T SOD1 mutation.
Lopate G, Baloh RH, Al-Lozi MT, Miller TM, Fernandes Filho JA, Ni O, Leston A, Florence J, Schierbecker J, Allred P
Amyotroph Lateral Scler. 2010; 11(1-2)232-6. doi: 10.3109/17482960902898069.

PMID:
    20184521
    [PubMed - indexed for MEDLINE]
Related citations


Mutational spectrum of DMD mutations in dystrophinopathy patients: application of modern diagnostic techniques to a large cohort.
Flanigan KM, Dunn DM, von Niederhausern A, Soltanzadeh P, Gappmaier E, Howard MT, Sampson JB, Mendell JR, Wall C, King WM, Pestronk A, Florence JM, Connolly AM, Mathews KD, Stephan CM, Laubenthal KS, Wong BL, Morehart PJ, Meyer A, Finkel RS, Bonnemann CG, Medne L, Day JW, Dalton JC, Margolis MK, Hinton VJ, United Dystrophinopathy Project Consortium, Weiss RB
Hum Mutat. 2009 Dec; 30(12)1657-66. doi: 10.1002/humu.21114.

PMID:
    19937601
    [PubMed - indexed for MEDLINE]
Related citations


A randomized controlled trial of resistance exercise in individuals with ALS.
Bello-Haas VD, Florence JM, Kloos AD, Scheirbecker J, Lopate G, Hayes SM, Pioro EP, Mitsumoto H
Neurology. 2007 Jun 5; 68(23)2003-7.

PMID:
    17548549
    [PubMed - indexed for MEDLINE]
Related citations


Motor neuron disease associated with copper deficiency.
Weihl CC, Lopate G
Muscle Nerve. 2006 Dec; 34(6)789-93.

PMID:
    16929546
    [PubMed - indexed for MEDLINE]
Related citations


Brachio-cervical inflammatory myopathies: clinical, immune, and myopathologic features.
Pestronk A, Kos K, Lopate G, Al-Lozi MT
Arthritis Rheum. 2006 May; 54(5)1687-96.

PMID:
    16646041
    [PubMed - indexed for MEDLINE]
Related citations


Frequency of spinal arteriovenous malformations in patients with unexplained myelopathy.
Strom RG, Derdeyn CP, Moran CJ, Cross DT, Esper GJ, Mazumdar A, Al-Lozi M, Lopate G, Pestronk A
Neurology. 2006 Mar 28; 66(6)928-31.

PMID:
    16567716
    [PubMed - indexed for MEDLINE]
Related citations


Peripheral neuropathy in an outpatient cohort of patients with Sjögren's syndrome.
Lopate G, Pestronk A, Al-Lozi M, Lynch T, Florence J, Miller T, Levine T, Rampy T, Beson B, Ramneantu I
Muscle Nerve. 2006 May; 33(5)672-6.

PMID:
    16453296
    [PubMed - indexed for MEDLINE]
Related citations


Peripheral neuropathies in Waldenström's macroglobulinaemia.
Levine T, Pestronk A, Florence J, Al-Lozi MT, Lopate G, Miller T, Ramneantu I, Waheed W, Stambuk M, Stone MJ, Choksi R
J Neurol Neurosurg Psychiatry. 2006 Feb; 77(2)224-8.

PMID:
    16421127
    [PubMed - indexed for MEDLINE]
Related citations


Anti-sulfatide antibodies in HIV-infected individuals with sensory neuropathy.
Lopate G, Pestronk A, Evans S, Li L, Clifford D
Neurology. 2005 May 10; 64(9)1632-4.

PMID:
    15883332
    [PubMed - indexed for MEDLINE]
Related citations


Treatment of chronic inflammatory demyelinating polyneuropathy with high-dose intermittent intravenous methylprednisolone.
Lopate G, Pestronk A, Al-Lozi M
Arch Neurol. 2005 Feb; 62(2)249-54.

PMID:
    15710853
    [PubMed - indexed for MEDLINE]
Related citations


Sensory exam with a quantitative tuning fork: rapid, sensitive and predictive of SNAP amplitude.
Pestronk A, Florence J, Levine T, Al-Lozi MT, Lopate G, Miller T, Ramneantu I, Waheed W, Stambuk M
Neurology. 2004 Feb 10; 62(3)461-4.

PMID:
    14872031
    [PubMed - indexed for MEDLINE]
Related citations