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Geoffrey L. Uy, MD

Assistant Professor, Medicine
Division of Oncology
Section, Bone Marrow Transplant and Leukemia

Specialty Areas

Bone Marrow Transplant
Oncology
Hematologic Malignancies

Board Certifications

Internal Medicine
Oncology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Bone marrow transplant, oncology, cancer, lymphoma, leukemia, aplastic anemia

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Siteman Cancer Center

4921 Parkview Place
St. Louis, MO 63110
Phone: 314-747-7222

Suite: B
Floor: 7
Office Phone: 314-454-8304
Fax: 314-454-7751

Education

Education

Fellowship: Hematology-Oncology, Washington University School of Medicine, St. Louis, Missouri 2007
Residency: Internal Medicine, Washington University School of Medicine, Barnes-Jewish Hospital, St. Louis, Missouri 2003
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 2001
B.S.: Cornell University, Ithaca, New York 1996

Publication & Research

Publication & Research

Intergroup LEAP trial (S1612): A randomized phase 2/3 platform trial to test novel therapeutics in medically less fit older adults with acute myeloid leukemia.
Walter RB, Michaelis LC, Othus M, Uy GL, Radich JP, Little RF, Hita S, Saini L, Foran JM, Gerds AT, Klepin HD, Hay AE, Assouline S, Lancet JE, Couban S, Litzow MR, Stone RM, Erba HP
Am J Hematol. 2018 Feb; 93(2)E49-E52. doi: 10.1002/ajh.24980.

PMID:
    29164656
    [PubMed - in process]
Related citations


Patterns of infectious complications in acute myeloid leukemia and myelodysplastic syndromes patients treated with 10-day decitabine regimen.
Ali AM, Weisel D, Gao F, Uy GL, Cashen AF, Jacoby MA, Wartman LD, Ghobadi A, Pusic I, Romee R, Fehniger TA, Stockerl-Goldstein KE, Vij R, Oh ST, Abboud CN, Schroeder MA, Westervelt P, DiPersio JF, Welch JS
Cancer Med. 2017 Dec; 6(12)2814-2821. doi: 10.1002/cam4.1231.

PMID:
    29058375
    [PubMed - in process]
Related citations


US Intergroup Study of Chemotherapy Plus Dasatinib and Allogeneic Stem Cell Transplant in Philadelphia Chromosome Positive ALL.
Ravandi F, Othus M, O'Brien SM, Forman SJ, Ha CS, Wong JYC, Tallman MS, Paietta E, Racevskis J, Uy GL, Horowitz M, Takebe N, Little R, Borate U, Kebriaei P, Kingsbury L, Kantarjian HM, Radich JP, Erba HP, Appelbaum FR
Blood Adv. 2016 Dec 27; 1(3)250-259. doi: 10.1182/bloodadvances.2016001495.

PMID:
    29046900
    [PubMed]
Related citations


A phase 2 study incorporating sorafenib into the chemotherapy for older adults with <i>FLT3</i>-mutated acute myeloid leukemia: CALGB 11001.
Uy GL, Mandrekar SJ, Laumann K, Marcucci G, Zhao W, Levis MJ, Klepin HD, Baer MR, Powell BL, Westervelt P, DeAngelo DJ, Stock W, Sanford B, Blum WG, Bloomfield CD, Stone RM, Larson RA
Blood Adv. 2017 Jan 24; 1(5)331-340. doi: 10.1182/bloodadvances.2016003053.

PMID:
    29034366
    [PubMed]
Related citations


Junior investigators: Get engaged in the Alliance for Clinical Trials in Oncology.
Uy GL, Katz MHG, Boughey JC
Bull Am Coll Surg. 2017 Apr; 102(4)62-3.

PMID:
    28920650
    [PubMed - indexed for MEDLINE]
Related citations


NCCN Guidelines Insights: Acute Lymphoblastic Leukemia, Version 1.2017.
Brown PA, Shah B, Fathi A, Wieduwilt M, Advani A, Aoun P, Barta SK, Boyer MW, Bryan T, Burke PW, Cassaday R, Coccia PF, Coutre SE, Damon LE, DeAngelo DJ, Frankfurt O, Greer JP, Kantarjian HM, Klisovic RB, Kupfer G, Litzow M, Liu A, Mattison R, Park J, Rubnitz J, Saad A, Uy GL, Wang ES, Gregory KM, Ogba N
J Natl Compr Canc Netw. 2017 Sep; 15(9)1091-1102. doi: 10.6004/jnccn.2017.0147.

PMID:
    28874594
    [PubMed - in process]
Related citations


Results of a Prospective Randomized, Open-Label, Noninferiority Study of Tbo-Filgrastim (Granix) versus Filgrastim (Neupogen) in Combination with Plerixafor for Autologous Stem Cell Mobilization in Patients with Multiple Myeloma and Non-Hodgkin Lymphoma.
Bhamidipati PK, Fiala MA, Grossman BJ, DiPersio JF, Stockerl-Goldstein K, Gao F, Uy GL, Westervelt P, Schroeder MA, Cashen AF, Abboud CN, Vij R
Biol Blood Marrow Transplant. 2017 Dec; 23(12)2065-2069. doi: 10.1016/j.bbmt.2017.07.023.

PMID:
    28797783
    [PubMed - in process]
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Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia.
Papaioannou D, Nicolet D, Volinia S, Mrózek K, Yan P, Bundschuh R, Carroll AJ, Kohlschmidt J, Blum W, Powell BL, Uy GL, Kolitz JE, Wang ES, Eisfeld AK, Orwick SJ, Lucas DM, Caligiuri MA, Stone RM, Byrd JC, Garzon R, Bloomfield CD
Haematologica. 2017 Aug; 102(8)1391-1400. doi: 10.3324/haematol.2017.166215.

PMID:
    28473620
    [PubMed - in process]
Related citations


Fresh or Cryopreserved CD34<sup>+</sup>-Selected Mobilized Peripheral Blood Stem and Progenitor Cells for the Treatment of Poor Graft Function after Allogeneic Hematopoietic Cell Transplantation.
Ghobadi A, Fiala MA, Ramsingh G, Gao F, Abboud CN, Stockerl-Goldstein K, Uy GL, Grossman BJ, Westervelt P, DiPersio JF
Biol Blood Marrow Transplant. 2017 Jul; 23(7)1072-1077. doi: 10.1016/j.bbmt.2017.03.019.

PMID:
    28323004
    [PubMed - in process]
Related citations


Mobilization of allogeneic peripheral blood stem cell donors with intravenous plerixafor mobilizes a unique graft.
Schroeder MA, Rettig MP, Lopez S, Christ S, Fiala M, Eades W, Mir FA, Shao J, McFarland K, Trinkaus K, Shannon W, Deych E, Yu J, Vij R, Stockerl-Goldstein K, Cashen AF, Uy GL, Abboud CN, Westervelt P, DiPersio JF
Blood. 2017 May 11; 129(19)2680-2692. doi: 10.1182/blood-2016-09-739722.

PMID:
    28292947
    [PubMed - indexed for MEDLINE]
Related citations


A phase 1/2 study of chemosensitization with plerixafor plus G-CSF in relapsed or refractory acute myeloid leukemia.
Uy GL, Rettig MP, Stone RM, Konopleva MY, Andreeff M, McFarland K, Shannon W, Fletcher TR, Reineck T, Eades W, Stockerl-Goldstein K, Abboud CN, Jacoby MA, Westervelt P, DiPersio JF
Blood Cancer J. 2017 Mar 10; 7(3)e542. doi: 10.1038/bcj.2017.21.

PMID:
    28282031
    [PubMed - in process]
Related citations


T Cell-Replete Peripheral Blood Haploidentical Hematopoietic Cell Transplantation with Post-Transplantation Cyclophosphamide Results in Outcomes Similar to Transplantation from Traditionally Matched Donors in Active Disease Acute Myeloid Leukemia.
How J, Slade M, Vu K, DiPersio JF, Westervelt P, Uy GL, Abboud CN, Vij R, Schroeder MA, Fehniger TA, Romee R
Biol Blood Marrow Transplant. 2017 Apr; 23(4)648-653. doi: 10.1016/j.bbmt.2017.01.068.

PMID:
    28087457
    [PubMed - in process]
Related citations


Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy.
Duncavage EJ, Uy GL, Petti AA, Miller CA, Lee YS, Tandon B, Gao F, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Jacoby MA, Cashen AF, Wartman LD, Walter MJ, Westervelt P, Link DC, DiPersio JF, Ley TJ, Welch JS
Blood. 2017 Mar 9; 129(10)1397-1401. doi: 10.1182/blood-2016-10-745273.

PMID:
    28082444
    [PubMed - indexed for MEDLINE]
Related citations


Serum Metabolomic Profiles Identify ER-Positive Early Breast Cancer Patients at Increased Risk of Disease Recurrence in a Multicenter Population.
Hart CD, Vignoli A, Tenori L, Uy GL, Van To T, Adebamowo C, Hossain SM, Biganzoli L, Risi E, Love RR, Luchinat C, Di Leo A
Clin Cancer Res. 2017 Mar 15; 23(6)1422-1431. doi: 10.1158/1078-0432.CCR-16-1153.

PMID:
    28082280
    [PubMed - in process]
Related citations


Single institution experience with G-CSF mobilized T-cell replete haploidentical hematopoietic cell transplantation.
Huselton E, Slade M, DiPersio JF, Westervelt P, Vij R, Uy GL, Fehniger TA, Abboud CN, Gao F, Schroeder MA, Romee R
Bone Marrow Transplant. 2017 May; 52(5)769-771. doi: 10.1038/bmt.2016.354.

PMID:
    28067881
    [PubMed - in process]
Related citations


Epidemiology of infections following haploidentical peripheral blood hematopoietic cell transplantation.
Slade M, Goldsmith S, Romee R, DiPersio JF, Dubberke ER, Westervelt P, Uy GL, Lawrence SJ
Transpl Infect Dis. 2017 Feb; 19(1)doi: 10.1111/tid.12629.

PMID:
    28030755
    [PubMed - indexed for MEDLINE]
Related citations


TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes.
Welch JS, Petti AA, Miller CA, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Baty JD, Duncavage EJ, Tandon B, Lee YS, Wartman LD, Uy GL, Ghobadi A, Tomasson MH, Pusic I, Romee R, Fehniger TA, Stockerl-Goldstein KE, Vij R, Oh ST, Abboud CN, Cashen AF, Schroeder MA, Jacoby MA, Heath SE, Luber K, Janke MR, Hantel A, Khan N, Sukhanova MJ, Knoebel RW, Stock W, Graubert TA, Walter MJ, Westervelt P, Link DC, DiPersio JF, Ley TJ
N Engl J Med. 2016 Nov 24; 375(21)2023-2036. doi: 10.1056/NEJMoa1605949.

PMID:
    27959731
    [PubMed - indexed for MEDLINE]
Related citations


Cytomegalovirus viremia, disease, and impact on relapse in T-cell replete peripheral blood haploidentical hematopoietic cell transplantation with post-transplant cyclophosphamide.
Goldsmith SR, Slade M, DiPersio JF, Westervelt P, Lawrence SJ, Uy GL, Abboud CN, Vij R, Schroeder MA, Fehniger TA, Dubberke ER, Trinkaus K, Romee R
Haematologica. 2016 Nov; 101(11)e465-e468.

PMID:
    27443287
    [PubMed - in process]
Related citations


Dynamic changes in the clonal structure of MDS and AML in response to epigenetic therapy.
Uy GL, Duncavage EJ, Chang GS, Jacoby MA, Miller CA, Shao J, Heath S, Elliott K, Reineck T, Fulton RS, Fronick CC, O'Laughlin M, Ganel L, Abboud CN, Cashen AF, DiPersio JF, Wilson RK, Link DC, Welch JS, Ley TJ, Graubert TA, Westervelt P, Walter MJ
Leukemia. 2017 Apr; 31(4)872-881. doi: 10.1038/leu.2016.282.

PMID:
    27740633
    [PubMed - indexed for MEDLINE]
Related citations


Severe Cytokine-Release Syndrome after T Cell-Replete Peripheral Blood Haploidentical Donor Transplantation Is Associated with Poor Survival and Anti-IL-6 Therapy Is Safe and Well Tolerated.
Abboud R, Keller J, Slade M, DiPersio JF, Westervelt P, Rettig MP, Meier S, Fehniger TA, Abboud CN, Uy GL, Vij R, Trinkaus KM, Schroeder MA, Romee R
Biol Blood Marrow Transplant. 2016 Oct; 22(10)1851-1860. doi: 10.1016/j.bbmt.2016.06.010.

PMID:
    27318038
    [PubMed - in process]
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