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Faculty Physicians

Fred L Coste III, DO

Assistant Professor, Pediatrics
Division of Allergy, Immunology and Pulmonary Medicine
Director, Pediatric Pulmonary Fellowship Program

Specialty Areas

Pediatric Allergy
Pediatric Asthma
Pediatric Sleep Disorders
Pediatric Pulmonary Disease
Pediatric Cystic Fibrosis

Board Certifications

Pediatrics
Pediatric Pulmonology

Hospital Affiliations

Barnes-Jewish West County Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Asthma in children, pediatric allergies, lung disease, Prader-Willi syndrome, sleep disorders in infancy and children

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Office Phone: 314-454-2694
Fax: 314-454-2515

Barnes-Jewish West County Hospital
Medical Building Three

1020 N. Mason Road
St. Louis, MO 63141

Office Phone: 314-454-2694
Fax: 314-454-2515

Education

Education

Residency: Pediatrics, Winthrop University Hospital, Mineola, New York 2007
B.S.: Cornell University, Ithaca, New York 1998
Medical Degree: New York College of Osteopathic Medicine, Old Westbury, NY 2004
Fellowship: Pediatric Pulmonology, Washington University School of Medicine, St. Louis MO 63110 2010

Publication & Research

Publication & Research

STREAM: Elucidating How Alcohol Use Disorders are Managed in UK General Practice Today.
Coste F, Rahhali N, Wallace P
Alcohol Alcohol. 2016 Jan 21; pii: agv138.

PMID:
    26801743
    [PubMed - as supplied by publisher]
Related citations


VIRALpro: a tool to identify viral capsid and tail sequences.
Galiez C, Magnan CN, Coste F, Baldi P
Bioinformatics. 2016 Jan 5; pii: btv727.

PMID:
    26733451
    [PubMed - as supplied by publisher]
Related citations


An Update on Healthcare Resource Use and Economic Burden In Alzheimer's Disease In The United States (Us) From A Medicare Sample Analysis.
Coste F, Neumann PJ, Xie L, Sanon M, Bent-Ennakhil N, Wang Y, Kariburyo MF, Fillit H
Value Health. 2015 Nov; 18(7)A754. doi: 10.1016/j.jval.2015.09.2924.

PMID:
    26534224
    [PubMed]
Related citations


The nucleoid-associated protein HU enhances 8-oxoguanine base excision by the formamidopyrimidine-DNA glycosylase.
Le Meur R, Culard F, Nadan V, Goffinont S, Coste F, Guerin M, Loth K, Landon C, Castaing B
Biochem J. 2015 Oct 1; 471(1)13-23. doi: 10.1042/BJ20150387.

PMID:
    26392572
    [PubMed - indexed for MEDLINE]
Related citations


Amplitude spectrum distance: measuring the global shape divergence of protein fragments.
Galiez C, Coste F
BMC Bioinformatics. 2015 Aug 14; 16256. doi: 10.1186/s12859-015-0693-y.

PMID:
    26268224
    [PubMed - indexed for MEDLINE]
Related citations


Behavioral Hyperventilation and Central Sleep Apnea in Two Children.
Johnston TP, Tam-Williams J, Schmandt M, Patel AC, Cleveland C, Coste F, Kemp JS
J Clin Sleep Med. 2015 Apr; 11(4)487-9.

PMID:
    26106657
    [PubMed - in process]
Related citations


Role of Nerve Growth Factor in Development and Persistence of Experimental Pulmonary Hypertension.
Freund-Michel V, Cardoso Dos Santos M, Guignabert C, Montani D, Phan C, Coste F, Tu L, Dubois M, Girerd B, Courtois A, Humbert M, Savineau JP, Marthan R, Muller B
Am J Respir Crit Care Med. 2015 Aug 1; 192(3)342-55. doi: 10.1164/rccm.201410-1851OC.

PMID:
    26039706
    [PubMed - indexed for MEDLINE]
Related citations


ATP-dependent motor activity of the transcription termination factor Rho from Mycobacterium tuberculosis.
D'Heygère F, Schwartz A, Coste F, Castaing B, Boudvillain M
Nucleic Acids Res. 2015 Jul 13; 43(12)6099-111. doi: 10.1093/nar/gkv505.

PMID:
    25999346
    [PubMed - indexed for MEDLINE]
Related citations


Ventilatory control and supplemental oxygen in premature infants with apparent chronic lung disease.
Coste F, Ferkol T, Hamvas A, Cleveland C, Linneman L, Hoffman J, Kemp J
Arch Dis Child Fetal Neonatal Ed. 2015 May; 100(3)F233-7. doi: 10.1136/archdischild-2014-307272.

PMID:
    25716677
    [PubMed - indexed for MEDLINE]
Related citations


Monitoring RNA unwinding by the transcription termination factor Rho from Mycobacterium tuberculosis.
D'Heygère F, Schwartz A, Coste F, Castaing B, Boudvillain M
Methods Mol Biol. 2015; 1259293-311. doi: 10.1007/978-1-4939-2214-7_18.

PMID:
    25579593
    [PubMed - indexed for MEDLINE]
Related citations


Computed tomographic measurement of airway remodeling and emphysema in advanced chronic obstructive pulmonary disease. Correlation with pulmonary hypertension.
Dournes G, Laurent F, Coste F, Dromer C, Blanchard E, Picard F, Baldacci F, Montaudon M, Girodet PO, Marthan R, Berger P
Am J Respir Crit Care Med. 2015 Jan 1; 191(1)63-70. doi: 10.1164/rccm.201408-1423OC.

PMID:
    25393421
    [PubMed - indexed for MEDLINE]
Related citations


Zinc finger oxidation of Fpg/Nei DNA glycosylases by 2-thioxanthine: biochemical and X-ray structural characterization.
Biela A, Coste F, Culard F, Guerin M, Goffinont S, Gasteiger K, Cieśla J, Winczura A, Kazimierczuk Z, Gasparutto D, Carell T, Tudek B, Castaing B
Nucleic Acids Res. 2014; 42(16)10748-61. doi: 10.1093/nar/gku613.

PMID:
    25143530
    [PubMed - indexed for MEDLINE]
Related citations


Bile-mediated activation of the acrAB and tolC multidrug efflux genes occurs mainly through transcriptional derepression of ramA in Salmonella enterica serovar Typhimurium.
Baucheron S, Nishino K, Monchaux I, Canepa S, Maurel MC, Coste F, Roussel A, Cloeckaert A, Giraud E
J Antimicrob Chemother. 2014 Sep; 69(9)2400-6. doi: 10.1093/jac/dku140.

PMID:
    24816212
    [PubMed - indexed for MEDLINE]
Related citations


Ovalbumin-related protein X is a heparin-binding ov-serpin exhibiting antimicrobial activities.
Réhault-Godbert S, Labas V, Helloin E, Hervé-Grépinet V, Slugocki C, Berges M, Bourin MC, Brionne A, Poirier JC, Gautron J, Coste F, Nys Y
J Biol Chem. 2013 Jun 14; 288(24)17285-95. doi: 10.1074/jbc.M113.469759.

PMID:
    23615912
    [PubMed - indexed for MEDLINE]
Related citations


Drinking patterns and their predictive factors in CONTROL: a 12-month prospective study in a sample of alcohol-dependent patients initiating treatment.
Daeppen JB, Faouzi M, Sanglier T, Sanchez N, Coste F, Bertholet N
Alcohol Alcohol. 2013 Mar-Apr; 48(2)189-95. doi: 10.1093/alcalc/ags125.

PMID:
    23221315
    [PubMed - indexed for MEDLINE]
Related citations


CyanoLyase: a database of phycobilin lyase sequences, motifs and functions.
Bretaudeau A, Coste F, Humily F, Garczarek L, Le Corguillé G, Six C, Ratin M, Collin O, Schluchter WM, Partensky F
Nucleic Acids Res. 2013 Jan; 41(Database issue)D396-401. doi: 10.1093/nar/gks1091.

PMID:
    23175607
    [PubMed - indexed for MEDLINE]
Related citations


Methyl donor deficiency affects small-intestinal differentiation and barrier function in rats.
Bressenot A, Pooya S, Bossenmeyer-Pourie C, Gauchotte G, Germain A, Chevaux JB, Coste F, Vignaud JM, Guéant JL, Peyrin-Biroulet L
Br J Nutr. 2013 Feb 28; 109(4)667-77. doi: 10.1017/S0007114512001869.

PMID:
    22794784
    [PubMed - indexed for MEDLINE]
Related citations


Crystal structure of Diedel, a marker of the immune response of Drosophila melanogaster.
Coste F, Kemp C, Bobezeau V, Hetru C, Kellenberger C, Imler JL, Roussel A
PLoS One. 2012; 7(3)e33416. doi: 10.1371/journal.pone.0033416.

PMID:
    22442689
    [PubMed - indexed for MEDLINE]
Related citations


Binding of the RamR repressor to wild-type and mutated promoters of the RamA gene involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium.
Baucheron S, Coste F, Canepa S, Maurel MC, Giraud E, Culard F, Castaing B, Roussel A, Cloeckaert A
Antimicrob Agents Chemother. 2012 Feb; 56(2)942-8. doi: 10.1128/AAC.05444-11.

PMID:
    22123696
    [PubMed - indexed for MEDLINE]
Related citations


5-Hydroxy-5-methylhydantoin DNA lesion, a molecular trap for DNA glycosylases.
Le Bihan YV, Angeles Izquierdo M, Coste F, Aller P, Culard F, Gehrke TH, Essalhi K, Carell T, Castaing B
Nucleic Acids Res. 2011 Aug; 39(14)6277-90. doi: 10.1093/nar/gkr215.

PMID:
    21486746
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Interest in inflammatory markers in children associated with sleep-disordered breathing.  Dr Coste developed an educational model on lung transplantation to improve the hospital experience for these patients and their families