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F. Sessions Cole, MD

Park J. White, M.D., Professor of Pediatrics
Professor of Cell Biology and Physiology
Assistant Vice Chancellor for Children’s Health
Vice Chairman, Department of Pediatrics
Director, Division of Newborn Medicine
Chief Medical Officer, St. Louis Children’s Hospital

Specialty Areas

Newborn Medicine - Neonatology
Neonatal/Perinatal Medicine

Board Certifications

Neonatal-Perinatal Medicine
Pediatrics

Hospital Affiliations

Barnes-Jewish Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Inherited lung diseases of infancy, surfactant protein-B deficiency, newborn immunity, newborn infections, complement biosynthesis

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: Neonatal Intensive Care Unit (NICU), 5th Floor
Office Phone: 314-454-6148
Fax: 314-454-4633

Education

Education

Fellowship: Research in Neonatology and Cell Biology, the Joint Program in Neonatology, Brigham and Women's Hosp 1981
Residency: Senior Assistant, The Children's Hospital Medical Center, Boston, Massachusetts 1978
Residency: Junior Assistant, The Children's Hospital Medical Center, Boston, Massachusetts 1977
Medical Officer: General Medical Officer, United States Public Health Service Hospital, Brighton, Massachusetts 1976
Internship: Pediatrics, The Children's Hospital Medical Center, Boston, Massachusetts 1974
MD: Yale University School of Medicine, New Haven, Connecticut 1973
B.A.: Amherst College, Amherst, Massachusetts 1969

Publication & Research

Publication & Research

Functional Characterization of ABCA3 Mutations from Infants with Respiratory Distress Syndrome.
Wambach JA, Yang P, Wegner DJ, Heins HB, Kaliberova LN, Kaliberov SA, Curiel DT, White FV, Hamvas A, Hackett BP, Cole FS
Am J Respir Cell Mol Biol. 2016 Jul 2;

PMID:
    27374344
    [PubMed - as supplied by publisher]
Related citations


Genetic Factors Contribute to Risk for Neonatal Respiratory Distress Syndrome among Moderately Preterm, Late Preterm, and Term Infants.
Shen CL, Zhang Q, Meyer Hudson J, Cole FS, Wambach JA
J Pediatr. 2016 May; 17269-74.e2. doi: 10.1016/j.jpeds.2016.01.031.

PMID:
    26935785
    [PubMed - in process]
Related citations


ALG1-CDG: Clinical and Molecular Characterization of 39 Unreported Patients.
Ng BG, Shiryaev SA, Rymen D, Eklund EA, Raymond K, Kircher M, Abdenur JE, Alehan F, Midro AT, Bamshad MJ, Barone R, Berry GT, Brumbaugh JE, Buckingham KJ, Clarkson K, Cole FS, O'Connor S, Cooper GM, Van Coster R, Demmer LA, Diogo L, Fay AJ, Ficicioglu C, Fiumara A, Gahl WA, Ganetzky R, Goel H, Harshman LA, He M, Jaeken J, James PM, Katz D, Keldermans L, Kibaek M, Kornberg AJ, Lachlan K, Lam C, Yaplito-Lee J, Nickerson DA, Peters HL, Race V, Régal L, Rush JS, Rutledge SL, Shendure J, Souche E, Sparks SE, Trapane P, Sanchez-Valle A, Vilain E, Vøllo A, Waechter CJ, Wang RY, Wolfe LA, Wong DA, Wood T, Yang AC, University of Washington Center for Mendelian Genomics, Matthijs G, Freeze HH
Hum Mutat. 2016 Jul; 37(7)653-60. doi: 10.1002/humu.22983.

PMID:
    26931382
    [PubMed - in process]
Related citations


Population-based frequency of surfactant dysfunction mutations in a native Chinese cohort.
Chen YJ, Wambach JA, DePass K, Wegner DJ, Chen SK, Zhang QY, Heins H, Cole FS, Hamvas A
World J Pediatr. 2016 May; 12(2)190-5. doi: 10.1007/s12519-015-0047-x.

PMID:
    26547207
    [PubMed - in process]
Related citations


Respiratory failure in a term infant with cis and trans mutations in ABCA3.
Jackson T, Wegner DJ, White FV, Hamvas A, Cole FS, Wambach JA
J Perinatol. 2015 Mar; 35(3)231-2. doi: 10.1038/jp.2014.236.

PMID:
    25712598
    [PubMed - indexed for MEDLINE]
Related citations


Sequencing of idiopathic pulmonary fibrosis-related genes reveals independent single gene associations.
Coghlan MA, Shifren A, Huang HJ, Russell TD, Mitra RD, Zhang Q, Wegner DJ, Cole FS, Hamvas A
BMJ Open Respir Res. 2014; 1(1)e000057. doi: 10.1136/bmjresp-2014-000057.

PMID:
    25553246
    [PubMed]
Related citations


Minoxidil-associated anorexia in an infant with refractory hypertension.
Vesoulis ZA, Attarian SJ, Zeller B, Cole FS
Pharmacotherapy. 2014 Dec; 34(12)e341-4. doi: 10.1002/phar.1495.

PMID:
    25280267
    [PubMed - indexed for MEDLINE]
Related citations


Genotype-phenotype correlations for infants and children with ABCA3 deficiency.
Wambach JA, Casey AM, Fishman MP, Wegner DJ, Wert SE, Cole FS, Hamvas A, Nogee LM
Am J Respir Crit Care Med. 2014 Jun 15; 189(12)1538-43. doi: 10.1164/rccm.201402-0342OC.

PMID:
    24871971
    [PubMed - indexed for MEDLINE]
Related citations


Synonymous ABCA3 variants do not increase risk for neonatal respiratory distress syndrome.
Wambach JA, Wegner DJ, Heins HB, Druley TE, Mitra RD, Hamvas A, Cole FS
J Pediatr. 2014 Jun; 164(6)1316-21.e3. doi: 10.1016/j.jpeds.2014.02.021.

PMID:
    24657120
    [PubMed - indexed for MEDLINE]
Related citations


Rare recessive loss-of-function methionyl-tRNA synthetase mutations presenting as a multi-organ phenotype.
van Meel E, Wegner DJ, Cliften P, Willing MC, White FV, Kornfeld S, Cole FS
BMC Med Genet. 2013 Oct 8; 14106. doi: 10.1186/1471-2350-14-106.

PMID:
    24103465
    [PubMed - indexed for MEDLINE]
Related citations


Genetic variation in MKL2 and decreased downstream PCTAIRE1 expression in extreme, fatal primary human microcephaly.
Ramos EI, Bien-Willner GA, Li J, Hughes AE, Giacalone J, Chasnoff S, Kulkarni S, Parmacek M, Cole FS, Druley TE
Clin Genet. 2014 May; 85(5)423-32. doi: 10.1111/cge.12197.

PMID:
    23692340
    [PubMed - indexed for MEDLINE]
Related citations


Congenital lymphocytic choriomeningitis virus: when to consider the diagnosis.
Anderson JL, Levy PT, Leonard KB, Smyser CD, Tychsen L, Cole FS
J Child Neurol. 2014 Jun; 29(6)837-42. doi: 10.1177/0883073813486295.

PMID:
    23666045
    [PubMed - indexed for MEDLINE]
Related citations


Single ABCA3 mutations increase risk for neonatal respiratory distress syndrome.
Wambach JA, Wegner DJ, Depass K, Heins H, Druley TE, Mitra RD, An P, Zhang Q, Nogee LM, Cole FS, Hamvas A
Pediatrics. 2012 Dec; 130(6)e1575-82. doi: 10.1542/peds.2012-0918.

PMID:
    23166334
    [PubMed - indexed for MEDLINE]
Related citations


A method to determine the kinetics of multiple proteins in human infants with respiratory distress syndrome.
Bereman MS, Tomazela DM, Heins HS, Simonato M, Cogo PE, Hamvas A, Patterson BW, Cole FS, MacCoss MJ
Anal Bioanal Chem. 2012 Jun; 403(8)2397-402. doi: 10.1007/s00216-012-5953-3.

PMID:
    22526637
    [PubMed - indexed for MEDLINE]
Related citations


Increased risk for respiratory distress among white, male, late preterm and term infants.
Anadkat JS, Kuzniewicz MW, Chaudhari BP, Cole FS, Hamvas A
J Perinatol. 2012 Oct; 32(10)780-5. doi: 10.1038/jp.2011.191.

PMID:
    22222548
    [PubMed - indexed for MEDLINE]
Related citations


NIH Consensus Development Conference statement: inhaled nitric-oxide therapy for premature infants.
Cole FS, Alleyne C, Barks JD, Boyle RJ, Carroll JL, Dokken D, Edwards WH, Georgieff M, Gregory K, Johnston MV, Kramer M, Mitchell C, Neu J, Pursley DM, Robinson WM, Rowitch DH
Pediatrics. 2011 Feb; 127(2)363-9. doi: 10.1542/peds.2010-3507.

PMID:
    21220405
    [PubMed - indexed for MEDLINE]
Related citations


NIH consensus development conference: Inhaled nitric oxide therapy for premature infants.
Cole FS, Alleyne C, Barks JD, Boyle RJ, Carroll JL, Dokken D, Edwards WH, Georgieff M, Gregory K, Johnston MV, Kramer M, Mitchell C, Neu J, Pursley DM, Robinson W, Rowitch DH
NIH Consens State Sci Statements. 2010 Oct 29; 27(5)1-34.

PMID:
    21042341
    [PubMed - indexed for MEDLINE]
Related citations


Surfactant protein-C promoter variants associated with neonatal respiratory distress syndrome reduce transcription.
Wambach JA, Yang P, Wegner DJ, An P, Hackett BP, Cole FS, Hamvas A
Pediatr Res. 2010 Sep; 68(3)216-20. doi: 10.1203/00006450-201011001-00421.

PMID:
    20539253
    [PubMed - indexed for MEDLINE]
Related citations


Measurement of human surfactant protein-B turnover in vivo from tracheal aspirates using targeted proteomics.
Tomazela DM, Patterson BW, Hanson E, Spence KL, Kanion TB, Salinger DH, Vicini P, Barret H, Heins HB, Cole FS, Hamvas A, MacCoss MJ
Anal Chem. 2010 Mar 15; 82(6)2561-7. doi: 10.1021/ac1001433.

PMID:
    20178338
    [PubMed - indexed for MEDLINE]
Related citations


Inherited surfactant deficiency caused by uniparental disomy of rare mutations in the surfactant protein-B and ATP binding cassette, subfamily a, member 3 genes.
Hamvas A, Nogee LM, Wegner DJ, Depass K, Christodoulou J, Bennetts B, McQuade LR, Gray PH, Deterding RR, Carroll TR, Kammesheidt A, Kasch LM, Kulkarni S, Cole FS
J Pediatr. 2009 Dec; 155(6)854-859.e1. doi: 10.1016/j.jpeds.2009.06.006.

PMID:
    19647838
    [PubMed - indexed for MEDLINE]
Related citations