Patient Portal

Eric McDade, DO

Associate Professor, Cognitive Neurology/ Dementia

Specialty Areas

Dementia
Memory Disorders and Diagnosis

Board Certifications

Neurology
Behavioral Neurology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Diagnosis and treatment of dementia syndromes in adults including Alzheimer disease, Lewy body dementia, frontotemporal dementia, vascular cognitive and hereditary dementia syndromes. Additional interest in  young-onset dementia syndromes.

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Memory Diagnostic Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: (314) 286-1967
Fax: (314) 286-1985

Education

Education

Fellowship - Cognitive Neurology: Mayo Clinic, Rochester, MN 2010
Residency, Neurology: University of Maryland Medical School, Baltimore, Maryland 2008
Doctor of Osteopathy - General Medicine: Chicago College of Osteopathic Medicine, Downers Grove, IL 2004

Publication & Research

Publication & Research

Tau PET in autosomal dominant Alzheimer's disease: relationship with cognition, dementia and other biomarkers.
Gordon BA, Blazey TM, Christensen J, Dincer A, Flores S, Keefe S, Chen C, Su Y, McDade EM, Wang G, Li Y, Hassenstab J, Aschenbrenner A, Hornbeck R, Jack CR Jr, Ances BM, Berman SB, Brosch JR, Galasko D, Gauthier S, Lah JJ, Masellis M, van Dyck CH, Mintun MA, Klein G, Ristic S, Cairns NJ, Marcus DS, Xiong C, Holtzman DM, Raichle ME, Morris JC, Bateman RJ, Benzinger TLS
Brain. 2019 Feb 11; doi: 10.1093/brain/awz019.

PMID:
    30753379
    [PubMed - as supplied by publisher]
Related citations


Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease.
Preische O, Schultz SA, Apel A, Kuhle J, Kaeser SA, Barro C, Gräber S, Kuder-Buletta E, LaFougere C, Laske C, Vöglein J, Levin J, Masters CL, Martins R, Schofield PR, Rossor MN, Graff-Radford NR, Salloway S, Ghetti B, Ringman JM, Noble JM, Chhatwal J, Goate AM, Benzinger TLS, Morris JC, Bateman RJ, Wang G, Fagan AM, McDade EM, Gordon BA, Jucker M, Dominantly Inherited Alzheimer Network.
Nat Med. 2019 Feb; 25(2)277-283. doi: 10.1038/s41591-018-0304-3.

PMID:
    30664784
    [PubMed - in process]
Related citations


Simultaneously evaluating the effect of baseline levels and longitudinal changes in disease biomarkers on cognition in dominantly inherited Alzheimer's disease.
Wang G, Xiong C, McDade EM, Hassenstab J, Aschenbrenner AJ, Fagan AM, Benzinger TLS, Gordon BA, Morris JC, Li Y, Bateman RJ, Dominantly Inherited Alzheimer Network (DIAN).
Alzheimers Dement (N Y). 2018; 4669-676. doi: 10.1016/j.trci.2018.10.009.

PMID:
    30569014
    [PubMed]
Related citations


A novel cognitive disease progression model for clinical trials in autosomal-dominant Alzheimer's disease.
Wang G, Berry S, Xiong C, Hassenstab J, Quintana M, McDade EM, Delmar P, Vestrucci M, Sethuraman G, Bateman RJ, Dominantly Inherited Alzheimer Network Trials Unit.
Stat Med. 2018 Sep 20; 37(21)3047-3055. doi: 10.1002/sim.7811.

PMID:
    29761523
    [PubMed - in process]
Related citations


Antipsychotics Use in Parkinson Disease: Separating Appropriate Therapies from Treating Inappropriately.
McDade EM
Am J Geriatr Psychiatry. 2017 Jul; 25(7)706-707. doi: 10.1016/j.jagp.2017.03.001.

PMID:
    28416136
    [PubMed - in process]
Related citations


The DIAN-TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model.
Bateman RJ, Benzinger TL, Berry S, Clifford DB, Duggan C, Fagan AM, Fanning K, Farlow MR, Hassenstab J, McDade EM, Mills S, Paumier K, Quintana M, Salloway SP, Santacruz A, Schneider LS, Wang G, Xiong C, DIAN-TU Pharma Consortium for the Dominantly Inherited Alzheimer Network.
Alzheimers Dement. 2017 Jan; 13(1)8-19. doi: 10.1016/j.jalz.2016.07.005.

PMID:
    27583651
    [PubMed - indexed for MEDLINE]
Related citations


Rapidly-progressive catatonia responsive to zolpidem in a patient with ovarian teratoma-associated paraneoplastic encephalitis.
Amorim E, McDade EM
J Clin Neurosci. 2016 Aug; 30136-138. doi: 10.1016/j.jocn.2016.01.028.

PMID:
    26964475
    [PubMed - indexed for MEDLINE]
Related citations


The Dynamic Gait Index in Evaluating Patients with Normal Pressure Hydrocephalus for Cerebrospinal Fluid Diversion.
Chivukula S, Tempel ZJ, Zwagerman NT, Newman WC, Shin SS, Chen CJ, Gardner PA, McDade EM, Ducruet AF
World Neurosurg. 2015 Dec; 84(6)1871-6. doi: 10.1016/j.wneu.2015.08.021.

PMID:
    26320865
    [PubMed - indexed for MEDLINE]
Related citations


Longitudinal assessment of neuroimaging and clinical markers in autosomal dominant Alzheimer's disease: a prospective cohort study.
Yau WW, Tudorascu DL, McDade EM, Ikonomovic S, James JA, Minhas D, Mowrey W, Sheu LK, Snitz BE, Weissfeld L, Gianaros PJ, Aizenstein HJ, Price JC, Mathis CA, Lopez OL, Klunk WE
Lancet Neurol. 2015 Aug; 14(8)804-813. doi: 10.1016/S1474-4422(15)00135-0.

PMID:
    26139022
    [PubMed - indexed for MEDLINE]
Related citations


Factors associated with the onset and persistence of post-lumbar puncture headache.
Monserrate AE, Ryman DC, Ma S, Xiong C, Noble JM, Ringman JM, Morris JC, Danek A, Müller-Sarnowski F, Clifford DB, McDade EM, Brooks WS, Darby DG, Masters CL, Weston PS, Farlow MR, Graff-Radford NR, Salloway SP, Fagan AM, Oliver A, Bateman RJ, Dominantly Inherited Alzheimer Network.
JAMA Neurol. 2015 Mar; 72(3)325-32. doi: 10.1001/jamaneurol.2014.3974.

PMID:
    25622095
    [PubMed - indexed for MEDLINE]
Related citations


Arterial stiffness and β-amyloid progression in nondemented elderly adults.
Hughes TM, Kuller LH, Barinas-Mitchell EJ, McDade EM, Klunk WE, Cohen AD, Mathis CA, Dekosky ST, Price JC, Lopez OL
JAMA Neurol. 2014 May; 71(5)562-8. doi: 10.1001/jamaneurol.2014.186.

PMID:
    24687165
    [PubMed - indexed for MEDLINE]
Related citations


How well do MCI criteria predict progression to severe cognitive impairment and dementia?
Ganguli M, Lee CW, Snitz BE, Hughes TF, McDade EM, Chang CC
Alzheimer Dis Assoc Disord. 2014 Apr-Jun; 28(2)113-21. doi: 10.1097/WAD.0000000000000018.

PMID:
    24521821
    [PubMed - indexed for MEDLINE]
Related citations


Treatment of dementia with lewy bodies.
Boot BP, McDade EM, McGinnis SM, Boeve BF
Curr Treat Options Neurol. 2013 Dec; 15(6)738-64. doi: 10.1007/s11940-013-0261-6.

PMID:
    24222315
    [PubMed]
Related citations


Pulse wave velocity is associated with β-amyloid deposition in the brains of very elderly adults.
Hughes TM, Kuller LH, Barinas-Mitchell EJ, Mackey RH, McDade EM, Klunk WE, Aizenstein HJ, Cohen AD, Snitz BE, Mathis CA, Dekosky ST, Lopez OL
Neurology. 2013 Nov 5; 81(19)1711-8. doi: 10.1212/01.wnl.0000435301.64776.37.

PMID:
    24132374
    [PubMed - indexed for MEDLINE]
Related citations


Subtle gait changes in patients with REM sleep behavior disorder.
McDade EM, Boot BP, Christianson TJ, Pankratz VS, Boeve BF, Ferman TJ, Bieniek K, Hollman JH, Roberts RO, Mielke MM, Knopman DS, Petersen RC
Mov Disord. 2013 Nov; 28(13)1847-53. doi: 10.1002/mds.25653.

PMID:
    24130124
    [PubMed - indexed for MEDLINE]
Related citations


In vivo assessment of amyloid-β deposition in nondemented very elderly subjects.
Mathis CA, Kuller LH, Klunk WE, Snitz BE, Price JC, Weissfeld LA, Rosario BL, Lopresti BJ, Saxton JA, Aizenstein HJ, McDade EM, Kamboh MI, DeKosky ST, Lopez OL
Ann Neurol. 2013 Jun; 73(6)751-61. doi: 10.1002/ana.23797.

PMID:
    23596051
    [PubMed - indexed for MEDLINE]
Related citations


MRS in early and presymptomatic carriers of a novel octapeptide repeat insertion in the prion protein gene.
McDade EM, Boeve BF, Fields JA, Kumar N, Rademakers R, Baker MC, Knopman BD, Petersen RC, Jack CR Jr, Kantarci K
J Neuroimaging. 2013 Jul; 23(3)409-13. doi: 10.1111/j.1552-6569.2012.00717.x.

PMID:
    22612156
    [PubMed - indexed for MEDLINE]
Related citations


Age-related changes in the default mode network are more advanced in Alzheimer disease.
Jones DT, Machulda MM, Vemuri P, McDade EM, Zeng G, Senjem ML, Gunter JL, Przybelski SA, Avula RT, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr
Neurology. 2011 Oct 18; 77(16)1524-31. doi: 10.1212/WNL.0b013e318233b33d.

PMID:
    21975202
    [PubMed - indexed for MEDLINE]
Related citations


Normative spatiotemporal gait parameters in older adults.
Hollman JH, McDade EM, Petersen RC
Gait Posture. 2011 May; 34(1)111-8. doi: 10.1016/j.gaitpost.2011.03.024.

PMID:
    21531139
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Research focus on the use of neuroimaging and cerebrospinal fluid techniques to study the early markers of dementia as it relates to familial dementia syndromes, dementia prevention and clinical trials in dementia.