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Douglas L. Mann, MD

Professor, Internal Medicine
Lewin Professor and Chief, Cardiovascular Division
Cardiologist-in-Chief, Barnes Jewish Hospital, St. Louis, MO

Specialty Areas

Cardiology
Heart Failure / Transplant
Cardiovascular Disease

Board Certifications

Cardiology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Management of heart failure, transplant

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Heart & Vascular Center

4921 Parkview Place
St. Louis, MO 63110

Suite: A
Floor: 8
Office Phone: 314-362-1291
Fax: 314 362-8908

Education

Education

Fellowship- Clinical and Research: Cardiology, Massachusetts General Hospital, Boston, MA 1985
BA, Biology: Lafayette College, Easton, Pennsylvania 1974
Medical Degree: Temple University School of Medicine, Philadelphia, Pennsylvania 1979
Residency: Internal Medicine, Temple University Hospital, Philadelphia, Pennsylvania 1982
Fellowship - Research: Research Fellow in Cardiology, Temple University, Hospital, Philadelphia, Pennsylvania 1986
Fellowship: Cardiology, University of California at San Diego, San Diego, California 1984

Publication & Research

Publication & Research

Modified perceptual training in sport: A new classification framework.
Hadlow SM, Panchuk D, Mann DL, Portus MR, Abernethy B
J Sci Med Sport. 2018 Feb 3; pii: S1440-2440(18)30029-X. doi: 10.1016/j.jsams.2018.01.011.

PMID:
    29433921
    [PubMed - as supplied by publisher]
Related citations


TNF receptor-activated factor 2 mediates cardiac protection through noncanonical NF-κB signaling.
Evans S, Tzeng HP, Veis DJ, Matkovich S, Weinheimer C, Kovacs A, Barger PM, Mann DL
JCI Insight. 2018 Feb 8; 3(3)pii: 98278. doi: 10.1172/jci.insight.98278.

PMID:
    29415884
    [PubMed - as supplied by publisher]
Related citations


Beta-blockers for the treatment of heart failure with a mid-range ejection fraction: deja-vu all over again?
Wilcox JE, Mann DL
Eur Heart J. 2018 Jan 1; 39(1)36-38. doi: 10.1093/eurheartj/ehx663.

PMID:
    29237005
    [PubMed - in process]
Related citations


Targeting Myocardial Energetics in the Failing Heart: Are We There Yet?
Mann DL
Circ Heart Fail. 2017 Dec; 10(12)pii: e004658. doi: 10.1161/CIRCHEARTFAILURE.117.004658.

PMID:
    29217758
    [PubMed - in process]
Related citations


Recognition of self-DNA drives cardiac inflammation: why broken hearts fail.
Lavine KJ, Mann DL
Nat Med. 2017 Dec 7; 23(12)1400-1401. doi: 10.1038/nm.4455.

PMID:
    29216037
    [PubMed - in process]
Related citations


Impaired Protein Quality Control During Left Ventricular Remodeling in Mice With Cardiac Restricted Overexpression of Tumor Necrosis Factor.
Hartupee J, Szalai GD, Wang W, Ma X, Diwan A, Mann DL
Circ Heart Fail. 2017 Dec; 10(12)pii: e004252. doi: 10.1161/CIRCHEARTFAILURE.117.004252.

PMID:
    29203562
    [PubMed - indexed for MEDLINE]
Related citations


Structural and Functional Phenotyping of the Failing Heart: Is the Left Ventricular Ejection Fraction Obsolete?
Bristow MR, Kao DP, Breathett KK, Altman NL, Gorcsan J 3rd, Gill EA, Lowes BD, Gilbert EM, Quaife RA, Mann DL
JACC Heart Fail. 2017 Nov; 5(11)772-781. doi: 10.1016/j.jchf.2017.09.009.

PMID:
    29096787
    [PubMed - in process]
Related citations


Diagnostic accuracy of damage-associated molecular patterns (DAMPs) in patients with heart failure with a reduced ejection fraction.
Hartupee J, Patel R, Staloch L, Dávila-Román VG, de Las Fuentes L, Novak E, Mann DL
J Clin Transl Sci. 2017 Jun; 1(3)208-209. doi: 10.1017/cts.2017.11.

PMID:
    29082034
    [PubMed]
Related citations


Status of Early-Career Academic Cardiology: A Global Perspective.
Tong CW, Madhur MS, Rzeszut AK, Abdalla M, Abudayyeh I, Alexanderson E, Buber J, Feldman DN, Gopinathannair R, Hira RS, Kates AM, Kessler T, Leung S, Raj SR, Spatz ES, Turner MB, Valente AM, West K, Sivaram CA, Hill JA, Mann DL, Freeman AM
J Am Coll Cardiol. 2017 Oct 31; 70(18)2290-2303. doi: 10.1016/j.jacc.2017.09.030.

PMID:
    29073958
    [PubMed - indexed for MEDLINE]
Related citations


The Success of Sinister Right-Handers in Baseball.
Mann DL, Loffing F, Allen PM
N Engl J Med. 2017 Oct 26; 377(17)1688-1690. doi: 10.1056/NEJMc1711659.

PMID:
    29069559
    [PubMed - indexed for MEDLINE]
Related citations


High-Resolution Chromatin Mapping in Heart Failure: Some Answers, but More Questions.
Mann DL
Circulation. 2017 Oct 24; 136(17)1626-1628. doi: 10.1161/CIRCULATIONAHA.117.030938.

PMID:
    29061575
    [PubMed - in process]
Related citations


Epidemiology, pathophysiology and clinical outcomes for heart failure patients with a mid-range ejection fraction.
Rastogi A, Novak E, Platts AE, Mann DL
Eur J Heart Fail. 2017 Dec; 19(12)1597-1605. doi: 10.1002/ejhf.879.

PMID:
    29024350
    [PubMed - in process]
Related citations


Visual strategies underpinning the development of visual-motor expertise when hitting a ball.
Sarpeshkar V, Abernethy B, Mann DL
J Exp Psychol Hum Percept Perform. 2017 Oct; 43(10)1744-1772. doi: 10.1037/xhp0000465.

PMID:
    28967781
    [PubMed - indexed for MEDLINE]
Related citations


Searching for the elusive gift: advances in talent identification in sport.
Mann DL, Dehghansai N, Baker J
Curr Opin Psychol. 2017 Aug; 16128-133. doi: 10.1016/j.copsyc.2017.04.016.

PMID:
    28813336
    [PubMed]
Related citations


Aspirin Does Not Increase Heart Failure Events in Heart Failure Patients: From the WARCEF Trial.
Teerlink JR, Qian M, Bello NA, Freudenberger RS, Levin B, Di Tullio MR, Graham S, Mann DL, Sacco RL, Mohr JP, Lip GYH, Labovitz AJ, Lee SC, Ponikowski P, Lok DJ, Anker SD, Thompson JLP, Homma S, WARCEF Investigators.
JACC Heart Fail. 2017 Aug; 5(8)603-610. doi: 10.1016/j.jchf.2017.04.011.

PMID:
    28774396
    [PubMed - in process]
Related citations


Efficacy and Safety of Spironolactone in Acute Heart Failure: The ATHENA-HF Randomized Clinical Trial.
Butler J, Anstrom KJ, Felker GM, Givertz MM, Kalogeropoulos AP, Konstam MA, Mann DL, Margulies KB, McNulty SE, Mentz RJ, Redfield MM, Tang WHW, Whellan DJ, Shah M, Desvigne-Nickens P, Hernandez AF, Braunwald E, National Heart Lung and Blood Institute Heart Failure Clinical Research Network.
JAMA Cardiol. 2017 Sep 1; 2(9)950-958. doi: 10.1001/jamacardio.2017.2198.

PMID:
    28700781
    [PubMed - in process]
Related citations


The relationship between partial upper-airway obstruction and inter-breath transition period during sleep.
Mann DL, Edwards BA, Joosten SA, Hamilton GS, Landry S, Sands SA, Wilson SJ, Terrill PI
Respir Physiol Neurobiol. 2017 Oct; 24432-40. doi: 10.1016/j.resp.2017.06.006.

PMID:
    28676331
    [PubMed - indexed for MEDLINE]
Related citations


Impact of Preeclampsia on Clinical and Functional Outcomes in Women With Peripartum Cardiomyopathy.
Lindley KJ, Conner SN, Cahill AG, Novak E, Mann DL
Circ Heart Fail. 2017 Jun; 10(6)pii: e003797. doi: 10.1161/CIRCHEARTFAILURE.116.003797.

PMID:
    28572214
    [PubMed - indexed for MEDLINE]
Related citations


Abnormal Global Longitudinal Strain Predicts Future Deterioration of Left Ventricular Function in Heart Failure Patients With a Recovered Left Ventricular Ejection Fraction.
Adamo L, Perry A, Novak E, Makan M, Lindman BR, Mann DL
Circ Heart Fail. 2017 Jun; 10(6)pii: e003788. doi: 10.1161/CIRCHEARTFAILURE.116.003788.

PMID:
    28559418
    [PubMed - indexed for MEDLINE]
Related citations


CYP3A4 genotype is associated with sildenafil concentrations in patients with heart failure with preserved ejection fraction.
de Denus S, Rouleau JL, Mann DL, Huggins GS, Pereira NL, Shah SH, Cappola TP, Fouodjio R, Mongrain I, Dubé MP
Pharmacogenomics J. 2017 Apr 25; doi: 10.1038/tpj.2017.8.

PMID:
    28440343
    [PubMed - as supplied by publisher]
Related citations

Areas of Research Interest

Dr. Mann's primary area of research is in the molecular and cellular basis of heart failure, with a particular emphasis on the role of inflammatory mediators in disease progression in the failing heart.