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Douglas Joel McDonald, MD, MS

Professor, Orthopedic Surgery

Specialty Areas

Orthopedic Surgery
Musculoskeletal Oncology
Oncological Orthopedic Surgery
Pediatric Orthopedic Surgery

Board Certifications

Orthopedic Surgery

Hospital Affiliations

St. Louis Children's Hospital
Shriners Hospital for Children - St. Louis
Barnes-Jewish Hospital

Areas of Clinical Interest

Orthopedics, diagnosis and treatment of benign and malignant bone tumors; spinal tumors; limb salvage surgery of the extremities; Ewing's sarcoma, orthopedic reconstructive surgery of the hip

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Orthopedic Surgery Center

4921 Parkview Place
St. Louis, MO 63110

Suite: A
Floor: 6
Office Phone: 314-514-3500
Fax: 314-747-2599

Education

Education

Fellowship: Orthopedic Surgery, Istituto Ortopedico Rizzoli, Universita Di Bologna, Italy, 1988
Fellowship: Section of Orthopedic Oncology, Mayo Graduate School of Medicine, Rochester, Minnesota 1987
Residency: Orthopedic Surgery, Mayo Graduate School of Medicine, Rochester, Minnesota 1987
Master of Science: Orthopedic Surgery, Mayo Graduate School of Medicine, Rochester, Minnesota 1982
Medical Degree: University of Minnesota, Rochester, Minnesota 1978

Publication & Research

Publication & Research

Diminished anabolic signaling response to insulin induced by intramuscular lipid accumulation is associated with inflammation in aging but not obesity.
Rivas DA, McDonald DJ, Rice NP, Haran PH, Dolnikowski GG, Fielding RA
Am J Physiol Regul Integr Comp Physiol. 2016 Apr 1; 310(7)R561-9. doi: 10.1152/ajpregu.00198.2015.

PMID:
    26764052
    [PubMed - in process]
Related citations


Productive HIV-1 infection is enriched in CD4(-)CD8(-) double negative (DN) T cells at pleural sites of dual infection with HIV and Mycobacterium tuberculosis.
Meng Q, Canaday DH, McDonald DJ, Mayanja-Kizza H, Baseke J, Toossi Z
Arch Virol. 2016 Jan; 161(1)181-7. doi: 10.1007/s00705-015-2640-7.

PMID:
    26497177
    [PubMed - indexed for MEDLINE]
Related citations


Bacterial Membrane Vesicles Mediate the Release of Mycobacterium tuberculosis Lipoglycans and Lipoproteins from Infected Macrophages.
Athman JJ, Wang Y, McDonald DJ, Boom WH, Harding CV, Wearsch PA
J Immunol. 2015 Aug 1; 195(3)1044-53. doi: 10.4049/jimmunol.1402894.

PMID:
    26109643
    [PubMed - indexed for MEDLINE]
Related citations


Imaging evaluation of treated benign bone tumours.
Dobson MA, McDonald DJ, Wessell DE, Friedman MV
J Med Imaging Radiat Oncol. 2015 Oct; 59(5)599-604. doi: 10.1111/1754-9485.12329.

PMID:
    26108970
    [PubMed - in process]
Related citations


Surface-based chondroblastoma of the tibia: a unique presentation.
Demertzis JL, Kyriakos M, Connolly S, McDonald DJ
Skeletal Radiol. 2015 Jul; 44(7)1045-50. doi: 10.1007/s00256-015-2142-4.

PMID:
    25851832
    [PubMed - indexed for MEDLINE]
Related citations


Mapping the putative G protein-coupled receptor (GPCR) docking site on GPCR kinase 2: insights from intact cell phosphorylation and recruitment assays.
Beautrait A, Michalski KR, Lopez TS, Mannix KM, McDonald DJ, Cutter AR, Medina CB, Hebert AM, Francis CJ, Bouvier M, Tesmer JJ, Sterne-Marr R
J Biol Chem. 2014 Sep 5; 289(36)25262-75. doi: 10.1074/jbc.M114.593178.

PMID:
    25049229
    [PubMed - indexed for MEDLINE]
Related citations


CD4+ memory stem cells are infected by HIV-1 in a manner regulated in part by SAMHD1 expression.
Tabler CO, Lucera MB, Haqqani AA, McDonald DJ, Migueles SA, Connors M, Tilton JC
J Virol. 2014 May; 88(9)4976-86. doi: 10.1128/JVI.00324-14.

PMID:
    24554663
    [PubMed - indexed for MEDLINE]
Related citations


Mycobacterial phosphatidylinositol mannoside 6 (PIM6) up-regulates TCR-triggered HIV-1 replication in CD4+ T cells.
Rodriguez ME, Loyd CM, Ding X, Karim AF, McDonald DJ, Canaday DH, Rojas RE
PLoS One. 2013; 8(11)e80938. doi: 10.1371/journal.pone.0080938.

PMID:
    24282561
    [PubMed - indexed for MEDLINE]
Related citations


Accuracy of acetabular component position in hip arthroplasty.
Barrack RL, Krempec JA, Clohisy JC, McDonald DJ, Ricci WM, Ruh EL, Nunley RM
J Bone Joint Surg Am. 2013 Oct 2; 95(19)1760-8. doi: 10.2106/JBJS.L.01704.

PMID:
    24088968
    [PubMed - indexed for MEDLINE]
Related citations


Synovial hemangioma of the hip joint in a pediatric patient.
Demertzis JL, Kyriakos M, Loomans R, McDonald DJ, Wessell DE
Skeletal Radiol. 2014 Jan; 43(1)107-13. doi: 10.1007/s00256-013-1724-2.

PMID:
    24061493
    [PubMed - indexed for MEDLINE]
Related citations


Perspective on hydroxyapatite-coated collars for bone-bridging: commentary on an article by Melanie Jean Coathup, BSc(Hon), PhD, et al.: "Long-term survival of cemented distal femoral endoprostheses with a hydroxyapatite-coated collar. A histological study and a radiographic follow-up".
McDonald DJ
J Bone Joint Surg Am. 2013 Sep 4; 95(17)e1281-2. doi: 10.2106/JBJS.M.00525.

PMID:
    24005212
    [PubMed - indexed for MEDLINE]
Related citations


Early obstetric simulators in Australia.
Owen H, McDonald DJ
Med J Aust. 2013 May 6; 198(8)449-51.

PMID:
    23641999
    [PubMed - indexed for MEDLINE]
Related citations


Intra-articular synovial sarcoma.
Friedman MV, Kyriakos M, Matava MJ, McDonald DJ, Jennings JW, Wessell DE
Skeletal Radiol. 2013 Jun; 42(6)859-67. doi: 10.1007/s00256-013-1589-4.

PMID:
    23455705
    [PubMed - indexed for MEDLINE]
Related citations


Surgical technique: Iliosacral reconstruction with minimal spinal instrumentation.
Nassif NA, Buchowski JM, Osterman K, McDonald DJ
Clin Orthop Relat Res. 2013 Mar; 471(3)947-55. doi: 10.1007/s11999-012-2643-6.

PMID:
    23065355
    [PubMed - indexed for MEDLINE]
Related citations


Variants of uncertain significance in breast cancer-related genes: real-world implications for a clinical conundrum. Part one: clinical genetics recommendations.
Miller-Samuel S, MacDonald DJ, Weitzel JN, Santiago F, Martino MA, Namey T, Augustyn A, Mueller R, Forman A, Bradbury AR, Morris GJ
Semin Oncol. 2011 Aug; 38(4)469-80. doi: 10.1053/j.seminoncol.2011.04.008.

PMID:
    21810505
    [PubMed - indexed for MEDLINE]
Related citations


Incidence of symptomatic venous thromboembolism in oncologic patients undergoing lower-extremity endoprosthetic arthroplasty.
Ramo BA, Griffin AM, Gill CS, McDonald DJ, Wunder JS, Ferguson P, Bell RS, Phillips SE, Schwartz HS, Holt GE
J Bone Joint Surg Am. 2011 May 4; 93(9)847-54. doi: 10.2106/JBJS.H.01640.

PMID:
    21543674
    [PubMed - indexed for MEDLINE]
Related citations


Estimating beta-mixing coefficients.
McDonald DJ, Shalizi CR, Schervish M
JMLR Workshop Conf Proc. 2011; 15516-524.

PMID:
    26279742
    [PubMed]
Related citations


The effect of low intensity ultraviolet-C light on monoclonal antibodies.
Lorenz CM, Wolk BM, Quan CP, Alcala EW, Eng M, McDonald DJ, Matthews TC
Biotechnol Prog. 2009 Mar-Apr; 25(2)476-82. doi: 10.1002/btpr.157.

PMID:
    19340891
    [PubMed - indexed for MEDLINE]
Related citations


In vivo femoral head damage and its effect on polyethylene wear.
Ito H, Maloney CM, Crowninshield RD, Clohisy JC, McDonald DJ, Maloney WJ
J Arthroplasty. 2010 Feb; 25(2)302-8. doi: 10.1016/j.arth.2009.01.010.

PMID:
    19201153
    [PubMed - indexed for MEDLINE]
Related citations


Detection of occult bone metastases from head and neck squamous cell carcinoma: impact of positron emission tomography computed tomography with fluorodeoxyglucose F 18.
Basu D, Siegel BA, McDonald DJ, Nussenbaum B
Arch Otolaryngol Head Neck Surg. 2007 Aug; 133(8)801-5.

PMID:
    17709620
    [PubMed - indexed for MEDLINE]
Related citations