Patient Portal

Dineo Khabele, MD

Mitchell & Elaine Yanow Professor and Chair of Obstetrics & Gynecology
Division of Gynecologic Oncology 

Specialty Areas

Gynecologic Oncology

Board Certifications

Obstetrics and Gynecology
Gynecologic Oncology

Hospital Affiliations

Barnes-Jewish Hospital
Missouri Baptist Medical Center
St. Louis Children's Hospital

Areas of Clinical Interest

Gynecologic oncology, ovarian cancer, endometrial cancer, cervical cancer, vulva cancer, adnexal masses, tumors, hysterectomy, lymphadenectomy, endometrial adenocarcinomas, cervical intraepithelial neoplasia, gynecologic malignancies, ob/gyn, women's health

  • Location(s)
  • Education
  • Publication & Research

Location(s)

Location(s)

Center for Advanced Medicine
Gynecologic Treatment Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: `13
Office Phone: 314-362-3181
Fax: 866-282-1113

Missouri Baptist Medical Center
Building D

3023 N. Ballas Road
Fourth Floor, Suite 450
St. Louis, MO 63131

Suite: 450
Floor: 4
Office Phone: 314-996-6075
Fax: 314-996-6074

Education

Education

Research Fellowship: Cancer Biology (Ovarian Cancer): Albert Einstein College of Medicine and Montefiore Medical College, Bronx, NY 2004
Fellowship: Gynecologic Oncology: Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY 2001
Residency: Obstetrics and Gynecology: The New York Presbyterian Hospital, Weill-Cornell University Medical, New York, NY 1998
Medical Degree: College of Physicians and Surgeons, Columbia, University, New York, NY 1994

Publication & Research

Publication & Research

Ascites-induced compression alters the peritoneal microenvironment and promotes metastatic success in ovarian cancer.
Asem M, Young A, Oyama C, ClaureDeLaZerda A, Liu Y, Ravosa MJ, Gupta V, Jewell A, Khabele D, Stack MS
Sci Rep. 2020 Jul 17; 10(1)11913. doi: 10.1038/s41598-020-68639-2.

PMID:
    32681052
    [PubMed - in process]
Related citations


Pharmacological ascorbate induces 'BRCAness' and enhances the effects of Poly(ADP-Ribose) polymerase inhibitors against BRCA1/2 wild-type ovarian cancer.
Ma Y, Chen P, Drisko JA, Khabele D, Godwin AK, Chen Q
Oncol Lett. 2020 Apr; 19(4)2629-2638. doi: 10.3892/ol.2020.11364.

PMID:
    32218813
    [PubMed]
Related citations


A Call to Action: Black/African American Women Surgeon Scientists, Where are They?
Berry C, Khabele D, Johnson-Mann C, Henry-Tillman R, Joseph KA, Turner P, Pugh C, Fayanju OM, Backhus L, Sweeting R, Newman EA, Oseni T, Hasson RM, White C, Cobb A, Johnston FM, Stallion A, Karpeh M, Nwariaku F, Rodriguez LM, Jordan AH
Ann Surg. 2020 Jul; 272(1)24-29. doi: 10.1097/SLA.0000000000003786.

PMID:
    32209893
    [PubMed - in process]
Related citations


CCNE1 and BRD4 co-amplification in high-grade serous ovarian cancer is associated with poor clinical outcomes.
Petersen S, Wilson AJ, Hirst J, Roby KF, Fadare O, Crispens MA, Beeghly-Fadiel A, Khabele D
Gynecol Oncol. 2020 May; 157(2)405-410. doi: 10.1016/j.ygyno.2020.01.038.

PMID:
    32044108
    [PubMed - in process]
Related citations


Discovery of Furanone-Based Radiopharmaceuticals for Diagnostic Targeting of COX-1 in Ovarian Cancer.
Uddin MJ, Wilson AJ, Crews BC, Malerba P, Uddin MI, Kingsley PJ, Ghebreselasie K, Daniel CK, Nickels ML, Tantawy MN, Jashim E, Manning HC, Khabele D, Marnett LJ
ACS Omega. 2019 May 31; 4(5)9251-9261. doi: 10.1021/acsomega.9b01093.

PMID:
    31172046
    [PubMed]
Related citations


Human papillomavirus vaccination completion rates among gynecological providers: an institutional retrospective review.
Elsamadicy EA, Schneiter MK, Hull PC, Khabele D
Hum Vaccin Immunother. 2019; 15(7-8)1851-1855. doi: 10.1080/21645515.2019.1619405.

PMID:
    31091165
    [PubMed - indexed for MEDLINE]
Related citations


Bipolar Tumor-Associated Macrophages in Ovarian Cancer as Targets for Therapy.
Gupta V, Yull F, Khabele D
Cancers (Basel). 2018 Sep 29; 10(10)pii: E366. doi: 10.3390/cancers10100366.

PMID:
    30274280
    [PubMed]
Related citations


Heated Intraperitoneal Chemotherapy in the Management of Advanced Ovarian Cancer.
Jewell A, McMahon M, Khabele D
Cancers (Basel). 2018 Sep 1; 10(9)pii: E296. doi: 10.3390/cancers10090296.

PMID:
    30200420
    [PubMed]
Related citations


The BET inhibitor INCB054329 reduces homologous recombination efficiency and augments PARP inhibitor activity in ovarian cancer.
Wilson AJ, Stubbs M, Liu P, Ruggeri B, Khabele D
Gynecol Oncol. 2018 Jun; 149(3)575-584. doi: 10.1016/j.ygyno.2018.03.049.

PMID:
    29567272
    [PubMed - indexed for MEDLINE]
Related citations


Differential cyclooxygenase expression levels and survival associations in type I and type II ovarian tumors.
Beeghly-Fadiel A, Wilson AJ, Keene S, El Ramahi M, Xu S, Marnett LJ, Fadare O, Crispens MA, Khabele D
J Ovarian Res. 2018 Feb 27; 11(1)17. doi: 10.1186/s13048-018-0389-9.

PMID:
    29482584
    [PubMed - indexed for MEDLINE]
Related citations


BET Bromodomain Inhibition Synergizes with PARP Inhibitor in Epithelial Ovarian Cancer.
Karakashev S, Zhu H, Yokoyama Y, Zhao B, Fatkhutdinov N, Kossenkov AV, Wilson AJ, Simpkins F, Speicher D, Khabele D, Bitler BG, Zhang R
Cell Rep. 2017 Dec 19; 21(12)3398-3405. doi: 10.1016/j.celrep.2017.11.095.

PMID:
    29262321
    [PubMed - indexed for MEDLINE]
Related citations


Cervical Cancer Screening and Follow-Up Procedures in Women Age <21 Years Following New Screening Guidelines.
Foxx AM, Zhu Y, Mitchel E, Nikpay S, Khabele D, Griffin MR
J Adolesc Health. 2018 Feb; 62(2)170-175. doi: 10.1016/j.jadohealth.2017.08.027.

PMID:
    29174874
    [PubMed - indexed for MEDLINE]
Related citations


Augmented Serum Amyloid A1/2 Mediated by TNF-induced NF-κB in Human Serous Ovarian Epithelial Tumors.
Choi H, Ignacio RMC, Lee ES, Wilson AJ, Khabele D, Son DS
Immune Netw. 2017 Apr; 17(2)121-127. doi: 10.4110/in.2017.17.2.121.

PMID:
    28458624
    [PubMed]
Related citations


Blood type, ABO genetic variants, and ovarian cancer survival.
Cozzi GD, Levinson RT, Toole H, Snyder MR, Deng A, Crispens MA, Khabele D, Beeghly-Fadiel A
PLoS One. 2017; 12(4)e0175119. doi: 10.1371/journal.pone.0175119.

PMID:
    28448592
    [PubMed - indexed for MEDLINE]
Related citations


Pragmatic trial of an intervention to increase human papillomavirus vaccination in safety-net clinics.
Sanderson M, Canedo JR, Khabele D, Fadden MK, Harris C, Beard K, Burress M, Pinkerton H, Jackson C, Mayo-Gamble T, Hargreaves MK, Hull PC
BMC Public Health. 2017 Feb 2; 17(1)158. doi: 10.1186/s12889-017-4094-1.

PMID:
    28153042
    [PubMed - indexed for MEDLINE]
Related citations


Thresholds and timing of pre-operative thrombocytosis and ovarian cancer survival: analysis of laboratory measures from electronic medical records.
Cozzi GD, Samuel JM, Fromal JT, Keene S, Crispens MA, Khabele D, Beeghly-Fadiel A
BMC Cancer. 2016 Aug 8; 16612. doi: 10.1186/s12885-016-2660-z.

PMID:
    27502272
    [PubMed - indexed for MEDLINE]
Related citations


Panobinostat sensitizes cyclin E high, homologous recombination-proficient ovarian cancer to olaparib.
Wilson AJ, Sarfo-Kantanka K, Barrack T, Steck A, Saskowski J, Crispens MA, Khabele D
Gynecol Oncol. 2016 Oct; 143(1)143-151. doi: 10.1016/j.ygyno.2016.07.088.

PMID:
    27444036
    [PubMed - indexed for MEDLINE]
Related citations


Early Detection of Treatment-Induced Mitotic Arrest Using Temporal Diffusion Magnetic Resonance Spectroscopy.
Jiang X, Li H, Zhao P, Xie J, Khabele D, Xu J, Gore JC
Neoplasia. 2016 Jun; 18(6)387-97. doi: 10.1016/j.neo.2016.04.006.

PMID:
    27292027
    [PubMed - indexed for MEDLINE]
Related citations


Incidental placenta increta at the time of prophylactic hysterectomy for Lynch syndrome: Insights into individualized decision-making and surgical timing.
Nielsen TA, David SN, Desouki MM, Crispens MA, Khabele D
Gynecol Oncol Rep. 2015 Nov; 1420-2. doi: 10.1016/j.gore.2015.09.003.

PMID:
    26793766
    [PubMed]
Related citations


Microenvironmental effects limit efficacy of thymoquinone treatment in a mouse model of ovarian cancer.
Wilson AJ, Saskowski J, Barham W, Khabele D, Yull F
Mol Cancer. 2015 Nov 9; 14192. doi: 10.1186/s12943-015-0463-5.

PMID:
    26552746
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Ovarian cancer, gynecologic cancer, chemotherapy resistance, DNA repair, epigenetic targets, tumor microenvironment, cancer health disparities