Patient Portal

David L. Brody, MD, PhD

Norman J. Stupp Professor of Neurology

Specialty Areas

Neurological Rehabilitation
Brain Injury Rehabilitation
Neurology - Adult

Board Certifications

Neurology

Hospital Affiliations

Barnes-Jewish Hospital

Referral Information

Physician Referral Required

Areas of Clinical Interest

Traumatic brain injury, concussion, brain injury rehabilitation, offering second opinions, and advice on rehabilitative strategies.

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Neuroscience Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: 314-362-4503
Fax: 314-362-4566

Education

Education

Residency: Neurology, Washington University School of Medicine, St. Louis, Missouri 2004
Ph.D.: Johns Hopkins School of Medicine, Baltimore, Maryland 2000
Medical Degree: Johns Hopkins School of Medicine, Baltimore, Maryland 2000
B.A.: Stanford University, Stanford, California 1992

Publication & Research

Publication & Research

Astrocytic degeneration in chronic traumatic encephalopathy.
Hsu ET, Gangolli M, Su S, Holleran L, Stein TD, Alvarez VE, McKee AC, Schmidt RE, Brody DL
Acta Neuropathol. 2018 Sep 7; doi: 10.1007/s00401-018-1902-3.

PMID:
    30194648
    [PubMed - as supplied by publisher]
Related citations


Soluble amyloid-beta buffering by plaques in Alzheimer disease dementia versus high-pathology controls.
Esparza TJ, Gangolli M, Cairns NJ, Brody DL
PLoS One. 2018; 13(7)e0200251. doi: 10.1371/journal.pone.0200251.

PMID:
    29979775
    [PubMed - in process]
Related citations


modCHIMERA: a novel murine closed-head model of moderate traumatic brain injury.
Sauerbeck AD, Fanizzi C, Kim JH, Gangolli M, Bayly PV, Wellington CL, Brody DL, Kummer TT
Sci Rep. 2018 May 16; 8(1)7677. doi: 10.1038/s41598-018-25737-6.

PMID:
    29769541
    [PubMed - in process]
Related citations


Chief Concern: "I'm Worried I Have Chronic Traumatic Encephalopathy".
Brody DL
Ann Intern Med. 2018 Feb 20; 168(4)285-286. doi: 10.7326/M17-2707.

PMID:
    29310134
    [PubMed - in process]
Related citations


Delayed Hypoxemia after Traumatic Brain Injury Exacerbates Long-Term Behavioral Deficits.
Davies M, Jacobs A, Brody DL, Friess SH
J Neurotrauma. 2018 Mar 1; 35(5)790-801. doi: 10.1089/neu.2017.5354.

PMID:
    29149808
    [PubMed - in process]
Related citations


Traumatic brain injury in the prodromal period of Parkinson's disease: A large epidemiological study using medicare data.
Camacho-Soto A, Warden MN, Searles Nielsen S, Salter A, Brody DL, Prather H, Racette BA
Ann Neurol. 2017 Nov; 82(5)744-754. doi: 10.1002/ana.25074.

PMID:
    29024046
    [PubMed - indexed for MEDLINE]
Related citations


Test-retest reliability of high spatial resolution diffusion tensor and diffusion kurtosis imaging.
Shahim P, Holleran L, Kim JH, Brody DL
Sci Rep. 2017 Sep 11; 7(1)11141. doi: 10.1038/s41598-017-11747-3.

PMID:
    28894296
    [PubMed - in process]
Related citations


Diversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain.
Wildburger NC, Esparza TJ, LeDuc RD, Fellers RT, Thomas PM, Cairns NJ, Kelleher NL, Bateman RJ, Brody DL
Sci Rep. 2017 Aug 25; 7(1)9520. doi: 10.1038/s41598-017-10422-x.

PMID:
    28842697
    [PubMed - in process]
Related citations


Non-canonical soluble amyloid-beta aggregates and plaque buffering: controversies and future directions for target discovery in Alzheimer's disease.
Brody DL, Jiang H, Wildburger N, Esparza TJ
Alzheimers Res Ther. 2017 Aug 17; 9(1)62. doi: 10.1186/s13195-017-0293-3.

PMID:
    28818091
    [PubMed - indexed for MEDLINE]
Related citations


Minimal Long-Term Neurobehavioral Impairments after Endovascular Perforation Subarachnoid Hemorrhage in Mice.
Fanizzi C, Sauerbeck AD, Gangolli M, Zipfel GJ, Brody DL, Kummer TT
Sci Rep. 2017 Aug 8; 7(1)7569. doi: 10.1038/s41598-017-07701-y.

PMID:
    28790425
    [PubMed - in process]
Related citations


Quantitative validation of a nonlinear histology-MRI coregistration method using generalized Q-sampling imaging in complex human cortical white matter.
Gangolli M, Holleran L, Hee Kim J, Stein TD, Alvarez V, McKee AC, Brody DL
Neuroimage. 2017 Jun; 153152-167. doi: 10.1016/j.neuroimage.2017.03.059.

PMID:
    28365421
    [PubMed - indexed for MEDLINE]
Related citations


Alzheimer's Toxic Amyloid Beta Oligomers: Unwelcome Visitors to the Na/K ATPase alpha3 Docking Station.
DiChiara T, DiNunno N, Clark J, Bu RL, Cline EN, Rollins MG, Gong Y, Brody DL, Sligar SG, Velasco PT, Viola KL, Klein WL
Yale J Biol Med. 2017 Mar; 90(1)45-61.

PMID:
    28356893
    [PubMed - indexed for MEDLINE]
Related citations


Astroglial activation and altered amyloid metabolism in human repetitive concussion.
Shahim P, Tegner Y, Marklund N, Höglund K, Portelius E, Brody DL, Blennow K, Zetterberg H
Neurology. 2017 Apr 11; 88(15)1400-1407. doi: 10.1212/WNL.0000000000003816.

PMID:
    28283595
    [PubMed - indexed for MEDLINE]
Related citations


Disease-Modifying Effects of M<sub>1</sub> Muscarinic Acetylcholine Receptor Activation in an Alzheimer's Disease Mouse Model.
Lebois EP, Schroeder JP, Esparza TJ, Bridges TM, Lindsley CW, Conn PJ, Brody DL, Daniels JS, Levey AI
ACS Chem Neurosci. 2017 Jun 21; 8(6)1177-1187. doi: 10.1021/acschemneuro.6b00278.

PMID:
    28230352
    [PubMed - indexed for MEDLINE]
Related citations


Axonal disruption in white matter underlying cortical sulcus tau pathology in chronic traumatic encephalopathy.
Holleran L, Kim JH, Gangolli M, Stein T, Alvarez V, McKee A, Brody DL
Acta Neuropathol. 2017 Mar; 133(3)367-380. doi: 10.1007/s00401-017-1686-x.

PMID:
    28214960
    [PubMed - indexed for MEDLINE]
Related citations


Soluble Amyloid-beta Aggregates from Human Alzheimer's Disease Brains.
Esparza TJ, Wildburger NC, Jiang H, Gangolli M, Cairns NJ, Bateman RJ, Brody DL
Sci Rep. 2016 Dec 5; 638187. doi: 10.1038/srep38187.

PMID:
    27917876
    [PubMed - indexed for MEDLINE]
Related citations


Traumatic brain injuries.
Blennow K, Brody DL, Kochanek PM, Levin H, McKee A, Ribbers GM, Yaffe K, Zetterberg H
Nat Rev Dis Primers. 2016 Nov 17; 216084. doi: 10.1038/nrdp.2016.84.

PMID:
    27853132
    [PubMed - indexed for MEDLINE]
Related citations


Statements of Agreement From the Targeted Evaluation and Active Management (TEAM) Approaches to Treating Concussion Meeting Held in Pittsburgh, October 15-16, 2015.
Collins MW, Kontos AP, Okonkwo DO, Almquist J, Bailes J, Barisa M, Bazarian J, Bloom OJ, Brody DL, Cantu R, Cardenas J, Clugston J, Cohen R, Echemendia R, Elbin RJ, Ellenbogen R, Fonseca J, Gioia G, Guskiewicz K, Heyer R, Hotz G, Iverson GL, Jordan B, Manley G, Maroon J, McAllister T, McCrea M, Mucha A, Pieroth E, Podell K, Pombo M, Shetty T, Sills A, Solomon G, Thomas DG, Valovich McLeod TC, Yates T, Zafonte R
Neurosurgery. 2016 Dec; 79(6)912-929.

PMID:
    27741219
    [PubMed - indexed for MEDLINE]
Related citations


L-MYC Expression Maintains Self-Renewal and Prolongs Multipotency of Primary Human Neural Stem Cells.
Li Z, Oganesyan D, Mooney R, Rong X, Christensen MJ, Shahmanyan D, Perrigue PM, Benetatos J, Tsaturyan L, Aramburo S, Annala AJ, Lu Y, Najbauer J, Wu X, Barish ME, Brody DL, Aboody KS, Gutova M
Stem Cell Reports. 2016 Sep 13; 7(3)483-495. doi: 10.1016/j.stemcr.2016.07.013.

PMID:
    27546534
    [PubMed - indexed for MEDLINE]
Related citations


Delayed Hypoxemia Following Traumatic Brain Injury Exacerbates White Matter Injury.
Parikh U, Williams M, Jacobs A, Pineda JA, Brody DL, Friess SH
J Neuropathol Exp Neurol. 2016 Jun 10; pii: nlw045.

PMID:
    27288907
    [PubMed - as supplied by publisher]
Related citations