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David L. Brody, MD, PhD

Norman J. Stupp Professor of Neurology

Specialty Areas

Neurological Rehabilitation
Brain Injury Rehabilitation
Neurology - Adult

Board Certifications

Neurology

Hospital Affiliations

Barnes-Jewish Hospital

Referral Information

Physician Referral Required

Areas of Clinical Interest

Traumatic brain injury, concussion, brain injury rehabilitation, offering second opinions, and advice on rehabilitative strategies.

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Neuroscience Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: 314-362-4503
Fax: 314-362-4566

Education

Education

Residency: Neurology, Washington University School of Medicine, St. Louis, Missouri 2004
Ph.D.: Johns Hopkins School of Medicine, Baltimore, Maryland 2000
Medical Degree: Johns Hopkins School of Medicine, Baltimore, Maryland 2000
B.A.: Stanford University, Stanford, California 1992

Publication & Research

Publication & Research

Quantitative validation of a nonlinear histology-MRI coregistration method using generalized Q-sampling imaging in complex human cortical white matter.
Gangolli M, Holleran L, Hee Kim J, Stein TD, Alvarez V, McKee AC, Brody DL
Neuroimage. 2017 Mar 30; 153152-167. doi: 10.1016/j.neuroimage.2017.03.059.

PMID:
    28365421
    [PubMed - as supplied by publisher]
Related citations


Alzheimer's Toxic Amyloid Beta Oligomers: Unwelcome Visitors to the Na/K ATPase alpha3 Docking Station.
DiChiara T, DiNunno N, Clark J, Bu RL, Cline EN, Rollins MG, Gong Y, Brody DL, Sligar SG, Velasco PT, Viola KL, Klein WL
Yale J Biol Med. 2017 Mar; 90(1)45-61.

PMID:
    28356893
    [PubMed - in process]
Related citations


Astroglial activation and altered amyloid metabolism in human repetitive concussion.
Shahim P, Tegner Y, Marklund N, Höglund K, Portelius E, Brody DL, Blennow K, Zetterberg H
Neurology. 2017 Apr 11; 88(15)1400-1407. doi: 10.1212/WNL.0000000000003816.

PMID:
    28283595
    [PubMed - indexed for MEDLINE]
Related citations


Disease-Modifying Effects of M<sub>1</sub> Muscarinic Acetylcholine Receptor Activation in an Alzheimer's Disease Mouse Model.
Lebois EP, Schroeder JP, Esparza TJ, Bridges TM, Lindsley CW, Conn PJ, Brody DL, Daniels JS, Levey AI
ACS Chem Neurosci. 2017 Mar 7; doi: 10.1021/acschemneuro.6b00278.

PMID:
    28230352
    [PubMed - as supplied by publisher]
Related citations


Axonal disruption in white matter underlying cortical sulcus tau pathology in chronic traumatic encephalopathy.
Holleran L, Kim JH, Gangolli M, Stein T, Alvarez V, McKee A, Brody DL
Acta Neuropathol. 2017 Mar; 133(3)367-380. doi: 10.1007/s00401-017-1686-x.

PMID:
    28214960
    [PubMed - in process]
Related citations


Soluble Amyloid-beta Aggregates from Human Alzheimer's Disease Brains.
Esparza TJ, Wildburger NC, Jiang H, Gangolli M, Cairns NJ, Bateman RJ, Brody DL
Sci Rep. 2016 Dec 5; 638187. doi: 10.1038/srep38187.

PMID:
    27917876
    [PubMed - in process]
Related citations


Traumatic brain injuries.
Blennow K, Brody DL, Kochanek PM, Levin H, McKee A, Ribbers GM, Yaffe K, Zetterberg H
Nat Rev Dis Primers. 2016 Nov 17; 216084. doi: 10.1038/nrdp.2016.84.

PMID:
    27853132
    [PubMed - in process]
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Statements of Agreement From the Targeted Evaluation and Active Management (TEAM) Approaches to Treating Concussion Meeting Held in Pittsburgh, October 15-16, 2015.
Collins MW, Kontos AP, Okonkwo DO, Almquist J, Bailes J, Barisa M, Bazarian J, Bloom OJ, Brody DL, Cantu R, Cardenas J, Clugston J, Cohen R, Echemendia R, Elbin RJ, Ellenbogen R, Fonseca J, Gioia G, Guskiewicz K, Heyer R, Hotz G, Iverson GL, Jordan B, Manley G, Maroon J, McAllister T, McCrea M, Mucha A, Pieroth E, Podell K, Pombo M, Shetty T, Sills A, Solomon G, Thomas DG, Valovich McLeod TC, Yates T, Zafonte R
Neurosurgery. 2016 Dec; 79(6)912-929.

PMID:
    27741219
    [PubMed - in process]
Related citations


L-MYC Expression Maintains Self-Renewal and Prolongs Multipotency of Primary Human Neural Stem Cells.
Li Z, Oganesyan D, Mooney R, Rong X, Christensen MJ, Shahmanyan D, Perrigue PM, Benetatos J, Tsaturyan L, Aramburo S, Annala AJ, Lu Y, Najbauer J, Wu X, Barish ME, Brody DL, Aboody KS, Gutova M
Stem Cell Reports. 2016 Sep 13; 7(3)483-95. doi: 10.1016/j.stemcr.2016.07.013.

PMID:
    27546534
    [PubMed - in process]
Related citations


Delayed Hypoxemia Following Traumatic Brain Injury Exacerbates White Matter Injury.
Parikh U, Williams M, Jacobs A, Pineda JA, Brody DL, Friess SH
J Neuropathol Exp Neurol. 2016 Jun 10; pii: nlw045.

PMID:
    27288907
    [PubMed - as supplied by publisher]
Related citations


Outcome Trends after US Military Concussive Traumatic Brain Injury.
Mac Donald CL, Johnson AM, Wierzechowski L, Kassner E, Stewart T, Nelson EC, Werner NJ, Adam OR, Rivet DJ, Flaherty SF, Oh JS, Zonies D, Fang R, Brody DL
J Neurotrauma. 2016 Jun 27; doi: 10.1089/neu.2016.4434.

PMID:
    27198861
    [PubMed - as supplied by publisher]
Related citations


Experimental subarachnoid haemorrhage results in multifocal axonal injury.
Kummer TT, Magnoni S, MacDonald CL, Dikranian K, Milner E, Sorrell J, Conte V, Benetatos JJ, Zipfel GJ, Brody DL
Brain. 2015 Sep; 138(Pt 9)2608-18. doi: 10.1093/brain/awv180.

PMID:
    26115676
    [PubMed - indexed for MEDLINE]
Related citations


Clinical and imaging assessment of acute combat mild traumatic brain injury in Afghanistan.
Adam O, Mac Donald CL, Rivet D, Ritter J, May T, Barefield M, Duckworth J, LaBarge D, Asher D, Drinkwine B, Woods Y, Connor M, Brody DL
Neurology. 2015 Jul 21; 85(3)219-27. doi: 10.1212/WNL.0000000000001758.

PMID:
    26109715
    [PubMed - indexed for MEDLINE]
Related citations


Quantitative assessments of traumatic axonal injury in human brain: concordance of microdialysis and advanced MRI.
Magnoni S, Mac Donald CL, Esparza TJ, Conte V, Sorrell J, Macrì M, Bertani G, Biffi R, Costa A, Sammons B, Snyder AZ, Shimony JS, Triulzi F, Stocchetti N, Brody DL
Brain. 2015 Aug; 138(Pt 8)2263-77. doi: 10.1093/brain/awv152.

PMID:
    26084657
    [PubMed - indexed for MEDLINE]
Related citations


Acute post-traumatic stress symptoms and age predict outcome in military blast concussion.
Mac Donald CL, Adam OR, Johnson AM, Nelson EC, Werner NJ, Rivet DJ, Brody DL
Brain. 2015 May; 138(Pt 5)1314-26. doi: 10.1093/brain/awv038.

PMID:
    25740219
    [PubMed - indexed for MEDLINE]
Related citations


Current and future diagnostic tools for traumatic brain injury: CT, conventional MRI, and diffusion tensor imaging.
Brody DL, Mac Donald CL, Shimony JS
Handb Clin Neurol. 2015; 127267-75. doi: 10.1016/B978-0-444-52892-6.00017-9.

PMID:
    25702222
    [PubMed - indexed for MEDLINE]
Related citations


Array tomography for the detection of non-dilated, injured axons in traumatic brain injury.
Bennett RE, Brody DL
J Neurosci Methods. 2015 Apr 30; 24525-36. doi: 10.1016/j.jneumeth.2015.02.005.

PMID:
    25687633
    [PubMed - indexed for MEDLINE]
Related citations


The pathophysiology of repetitive concussive traumatic brain injury in experimental models; new developments and open questions.
Brody DL, Benetatos J, Bennett RE, Klemenhagen KC, Mac Donald CL
Mol Cell Neurosci. 2015 May; 66(Pt B)91-8. doi: 10.1016/j.mcn.2015.02.005.

PMID:
    25684677
    [PubMed - indexed for MEDLINE]
Related citations


Decompressive craniectomy reduces white matter injury after controlled cortical impact in mice.
Friess SH, Lapidus JB, Brody DL
J Neurotrauma. 2015 Jun 1; 32(11)791-800. doi: 10.1089/neu.2014.3564.

PMID:
    25557588
    [PubMed - indexed for MEDLINE]
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The remarkable properties of amyloid-β derived from human Alzheimer's disease brain: swinging the streetlight.
Brody DL, Gross ML
Brain. 2014 Nov; 137(Pt 11)2874-5. doi: 10.1093/brain/awu261.

PMID:
    25344080
    [PubMed - indexed for MEDLINE]
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