Patient Portal

David G. Mutch, MD

Ira C. and Judith Gall Professor of Obstetrics and Gynecology
Division of Gynecologic Oncology
Vice Chair, Gynecology

Fellowship Director, Gynecologic Oncology

Specialty Areas

Gynecologic Oncology
Cervical Cancer
Ovarian Cancer
Endometrial Cancer

Board Certifications

Gynecologic Oncology
Obstetrics and Gynecology

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital
Missouri Baptist Medical Center
St. Louis Children's Hospital

Areas of Clinical Interest

Gynecologic oncology, endometrial cancer, vulva carcinoma, ovarian cancer, cervical cancer, adnexal masses, tumors, hysterectomy, lymphadenectomy, endometrial adenocarcinomas, cervical intraepithelial neoplasia, gynecologic malignancies, ob/gyn, women's health

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Missouri Baptist Medical Center
Building D

3023 N. Ballas Road
Fourth Floor, Suite 450
St. Louis, MO 63131

Office Phone: 314-996-6075
Fax: 314-996-6074

Center for Advanced Medicine
Gynecologic Treatment Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 13
Office Phone: 314-362-3181
Fax: 314-362-8644

Education

Education

Fellowship: Gynecologic Oncology, Duke University Medical Center, Durham, North Carolina 1987
Residency: Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri 1984
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 1980
B.A.: Carleton College, Northfield, Minnesota 1976

Publication & Research

Publication & Research

Nomogram for Predicting Individual Survival After Recurrence of Advanced-Stage, High-Grade Ovarian Carcinoma.
Rose PG, Java JJ, Salani R, Geller MA, Secord AA, Tewari KS, Bender DP, Mutch DG, Friedlander ML, Van Le L, Method MW, Hamilton CA, Lee RB, Wenham RM, Guntupalli SR, Markman M, Muggia FM, Armstrong DK, Bookman MA, Burger RA, Copeland LJ
Obstet Gynecol. 2019 Jan 8; doi: 10.1097/AOG.0000000000003086.

PMID:
    30633128
    [PubMed - as supplied by publisher]
Related citations


Postpartum salpingectomy: a procedure whose time has come.
Zamorano AS, Mutch DG
Am J Obstet Gynecol. 2019 Jan; 220(1)8-9. doi: 10.1016/j.ajog.2018.09.041.

PMID:
    30591122
    [PubMed - in process]
Related citations


A randomized phase II study of cabozantinib versus weekly paclitaxel in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer: An NRG Oncology/Gynecologic Oncology Group study.
Matulonis UA, Sill MW, Makker V, Mutch DG, Carlson JW, Darus CJ, Mannel RS, Bender DP, Crane EK, Aghajanian C
Gynecol Oncol. 2018 Dec 23; pii: S0090-8258(18)31460-4. doi: 10.1016/j.ygyno.2018.12.008.

PMID:
    30587441
    [PubMed - as supplied by publisher]
Related citations


Obesity counseling in obstetrics and gynecology: provider perceptions and barriers.
Huepenbecker SP, Wan L, Leon A, Rosen D, Hoff J, Kuroki LM, Fuh KC, Powell MA, Mutch DG, Colditz GA, Hagemann AR
Gynecol Oncol Rep. 2019 Feb; 2731-34. doi: 10.1016/j.gore.2018.12.001.

PMID:
    30582746
    [PubMed]
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Therapeutic Inhibition of the Receptor Tyrosine Kinase AXL Improves Sensitivity to Platinum and Taxane in Ovarian Cancer.
Quinn JM, Greenwade MM, Palisoul ML, Opara G, Massad K, Guo L, Zhao P, Beck-Noia H, Hagemann IS, Hagemann AR, McCourt CK, Thaker PH, Powell MA, Mutch DG, Fuh KC
Mol Cancer Ther. 2018 Nov 26; pii: molcanther.0537.2018. doi: 10.1158/1535-7163.MCT-18-0537.

PMID:
    30478151
    [PubMed - as supplied by publisher]
Related citations


Intensity Modulated Radiation Therapy and Image-Guided Adapted Brachytherapy for Cervix Cancer.
Lin AJ, Kidd E, Dehdashti F, Siegel BA, Mutic S, Thaker PH, Massad LS, Powell MA, Mutch DG, Markovina S, Schwarz J, Grigsby PW
Int J Radiat Oncol Biol Phys. 2018 Nov 14; pii: S0360-3016(18)33998-1. doi: 10.1016/j.ijrobp.2018.11.012.

PMID:
    30445171
    [PubMed - as supplied by publisher]
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Adipokines Deregulate Cellular Communication via Epigenetic Repression of <i>Gap Junction</i> Loci in Obese Endometrial Cancer.
Polusani SR, Huang YW, Huang G, Chen CW, Wang CM, Lin LL, Osmulski P, Lucio ND, Liu L, Hsu YT, Zhou Y, Lin CL, Aguilera-Barrantes I, Valente PT, Kost ER, Chen CL, Shim EY, Lee SE, Ruan J, Gaczynska ME, Yan P, Goodfellow PJ, Mutch DG, Jin VX, Nicholson BJ, Huang TH, Kirma NB
Cancer Res. 2019 Jan 1; 79(1)196-208. doi: 10.1158/0008-5472.CAN-18-1615.

PMID:
    30389702
    [PubMed - in process]
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Corrigendum to "Does adjuvant chemotherapy dose modification have an impact on the outcome of patients diagnosed with advanced stage ovarian cancer? An NRG Oncology/Gynecologic Oncology Group study" [Gynecol. Oncol. 151 (2018) 18-23].
Olawaiye AB, Java JJ, Krivak TC, Friedlander M, Mutch DG, Glaser G, Geller M, O'Malley DM, Wenham RM, Lee RB, Bodurka DC, Herzog TJ, Bookman MA
Gynecol Oncol. 2019 Jan; 152(1)220. doi: 10.1016/j.ygyno.2018.10.022.

PMID:
    30360899
    [PubMed - in process]
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Pathology of cancers of the female genital tract including molecular pathology.
Prat J, Mutch DG
Int J Gynaecol Obstet. 2018 Oct; 143 Suppl 293-108. doi: 10.1002/ijgo.12617.

PMID:
    30306579
    [PubMed - indexed for MEDLINE]
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Evaluation of Ovarian Cancer: Initial Application of Coregistered Photoacoustic Tomography and US.
Nandy S, Mostafa A, Hagemann IS, Powell MA, Amidi E, Robinson K, Mutch DG, Siegel C, Zhu Q
Radiology. 2018 Dec; 289(3)740-747. doi: 10.1148/radiol.2018180666.

PMID:
    30204078
    [PubMed - in process]
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SQ1274, a novel microtubule inhibitor, inhibits ovarian and uterine cancer cell growth.
Mills KA, Roach ST, Quinn JM, Guo L, Beck HM, Lomonosova E, Ilivicky AR, Starks CM, Lawrence JA, Hagemann AR, McCourt C, Thaker PH, Powell MA, Mutch DG, Fuh KC
Gynecol Oncol. 2018 Nov; 151(2)337-344. doi: 10.1016/j.ygyno.2018.08.008.

PMID:
    30190114
    [PubMed - indexed for MEDLINE]
Related citations


Does adjuvant chemotherapy dose modification have an impact on the outcome of patients diagnosed with advanced stage ovarian cancer? An NRG Oncology/Gynecologic Oncology Group study.
Olawaiye AB, Java JJ, Krivak TC, Friedlander M, Mutch DG, Glaser G, Geller M, O'Malley DM, Wenham RM, Lee RB, Bodurka DC, Herzog TJ, Bookman MA
Gynecol Oncol. 2018 Oct; 151(1)18-23. doi: 10.1016/j.ygyno.2018.07.021.

PMID:
    30135020
    [PubMed - indexed for MEDLINE]
Related citations


Gynecologic Oncologists' Perceptions of Palliative Care and Associated Barriers: A Survey of the Society of Gynecologic Oncology.
Cripe JC, Mills KA, Kuroki LK, Wan L, Hagemann AR, Fuh KC, Mutch DG, Powell MA, Thaker PH
Gynecol Obstet Invest. 2018 Aug 10; 1-6. doi: 10.1159/000491089.

PMID:
    30099446
    [PubMed - as supplied by publisher]
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Receipt of adjuvant endometrial cancer treatment according to race: an NRG Oncology/Gynecologic Oncology Group 210 Study.
Felix AS, Cohn DE, Brasky TM, Zaino R, Park K, Mutch DG, Creasman WT, Thaker PH, Walker JL, Moore RG, Lele SB, Guntupalli SR, Downs LS, Nagel CI, Boggess JF, Pearl ML, Ioffe OB, Randall ME, Brinton LA
Am J Obstet Gynecol. 2018 Nov; 219(5)459.e1-459.e11. doi: 10.1016/j.ajog.2018.08.002.

PMID:
    30096321
    [PubMed - in process]
Related citations


Lymphnode staging update in the American Joint Committee on Cancer 8th Edition cancer staging manual.
Olawaiye AB, Mutch DG
Gynecol Oncol. 2018 Jul; 150(1)7-8. doi: 10.1016/j.ygyno.2018.02.021.

PMID:
    29540290
    [PubMed - indexed for MEDLINE]
Related citations


Adenovirus platform enhances transduction efficiency of human mesenchymal stem cells: An opportunity for cellular carriers of targeted TRAIL-based TR3 biologics in ovarian cancer.
Kuroki LM, Jin X, Dmitriev IP, Kashentseva EA, Powell MA, Mutch DG, Dietz AB, Curiel DT, Hawkins WG, Spitzer D
PLoS One. 2017; 12(12)e0190125. doi: 10.1371/journal.pone.0190125.

PMID:
    29267342
    [PubMed - indexed for MEDLINE]
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Clinicopathologic characteristics associated with long-term survival in advanced epithelial ovarian cancer: an NRG Oncology/Gynecologic Oncology Group ancillary data study.
Hamilton CA, Miller A, Casablanca Y, Horowitz NS, Rungruang B, Krivak TC, Richard SD, Rodriguez N, Birrer MJ, Backes FJ, Geller MA, Quinn M, Goodheart MJ, Mutch DG, Kavanagh JJ, Maxwell GL, Bookman MA
Gynecol Oncol. 2018 Feb; 148(2)275-280. doi: 10.1016/j.ygyno.2017.11.018.

PMID:
    29195926
    [PubMed - indexed for MEDLINE]
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Predictive modeling for determination of microscopic residual disease at primary cytoreduction: An NRG Oncology/Gynecologic Oncology Group 182 Study.
Horowitz NS, Larry Maxwell G, Miller A, Hamilton CA, Rungruang B, Rodriguez N, Richard SD, Krivak TC, Fowler JM, Mutch DG, Van Le L, Lee RB, Argenta P, Bender D, Tewari KS, Gershenson D, Java JJ, Bookman MA
Gynecol Oncol. 2018 Jan; 148(1)49-55. doi: 10.1016/j.ygyno.2017.10.011.

PMID:
    29174555
    [PubMed - indexed for MEDLINE]
Related citations


MAX Mutations in Endometrial Cancer: Clinicopathologic Associations and Recurrent MAX p.His28Arg Functional Characterization.
Walker CJ, Rush CM, Dama P, O'Hern MJ, Cosgrove CM, Gillespie JL, Zingarelli RA, Smith B, Stein ME, Mutch DG, Shakya R, Chang CW, Selvendiran K, Song JW, Cohn DE, Goodfellow PJ
J Natl Cancer Inst. 2018 May 1; 110(5)517-526. doi: 10.1093/jnci/djx238.

PMID:
    29155953
    [PubMed - in process]
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Moving forward with actionable therapeutic targets and opportunities in endometrial cancer: NCI clinical trials planning meeting report on identifying key genes and molecular pathways for targeted endometrial cancer trials.
MacKay HJ, Levine DA, Bae-Jump VL, Bell DW, McAlpine JN, Santin A, Fleming GF, Mutch DG, Nephew KP, Wentzensen N, Goodfellow PJ, Dorigo O, Nijman HW, Broaddus R, Kohn EC
Oncotarget. 2017 Oct 13; 8(48)84579-84594. doi: 10.18632/oncotarget.19961.

PMID:
    29137450
    [PubMed]
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