Patient Portal

David G. Mutch, MD

Ira C. and Judith Gall Professor of Obstetrics and Gynecology
Division of Gynecologic Oncology
Vice Chair, Gynecology

Fellowship Director, Gynecologic Oncology

Specialty Areas

Gynecologic Oncology
Cervical Cancer
Ovarian Cancer
Endometrial Cancer

Board Certifications

Gynecologic Oncology
Obstetrics and Gynecology

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital
Missouri Baptist Medical Center
St. Louis Children's Hospital

Areas of Clinical Interest

Gynecologic oncology, endometrial cancer, vulva carcinoma, ovarian cancer, cervical cancer, adnexal masses, tumors, hysterectomy, lymphadenectomy, endometrial adenocarcinomas, cervical intraepithelial neoplasia, gynecologic malignancies, ob/gyn, women's health

  • Location(s)
  • Education
  • Publication & Research
  • Financial Disclosures

Location(s)

Location(s)

Missouri Baptist Medical Center
Building D

3023 N. Ballas Road
Fourth Floor, Suite 450
St. Louis, MO 63131

Office Phone: 314-996-6075
Fax: 314-996-6074

Center for Advanced Medicine
Gynecologic Treatment Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 13
Office Phone: 314-362-3181
Fax: 314-362-8644

Education

Education

Fellowship: Gynecologic Oncology, Duke University Medical Center, Durham, North Carolina 1987
Residency: Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri 1984
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 1980
B.A.: Carleton College, Northfield, Minnesota 1976

Publication & Research

Publication & Research

Treatment Compliance as a Major Barrier to Optimal Cervical Cancer Treatment in Guatemala.
Zamorano AS, Barnoya J, Gharzouzi E, Chrisman Robbins C, Orozco E, Polo Guerra S, Mutch DG
J Glob Oncol. 2019 May; 51-5. doi: 10.1200/JGO.18.00243.

PMID:
    31067142
    [PubMed - in process]
Related citations


Do gynecologic oncology patients with severely diminished renal function and urinary tract obstruction benefit from ureteral stenting or percutaneous nephrostomy?
Liang B, Lange SS, Massad LS, Dick R, Mills KA, Hagemann AR, McCourt CK, Thaker PH, Fuh KC, Mutch DG, Powell MA, Kuroki LM
Gynecol Oncol Rep. 2019 May; 28136-140. doi: 10.1016/j.gore.2019.04.007.

PMID:
    31061871
    [PubMed]
Related citations


SOX11 hypermethylation as a tumor biomarker in endometrial cancer.
Shan T, Uyar DS, Wang LS, Mutch DG, Huang TH, Rader JS, Sheng X, Huang YW
Biochimie. 2019 Mar 29; 1628-14. doi: 10.1016/j.biochi.2019.03.019.

PMID:
    30935961
    [PubMed - as supplied by publisher]
Related citations


Dicer1 Phosphomimetic Promotes Tumor Progression and Dissemination.
Aryal NK, Pant V, Wasylishen AR, Rimel BJ, Baseler L, El-Naggar AK, Mutch DG, Goodfellow PJ, Arur S, Lozano G
Cancer Res. 2019 May 15; 79(10)2662-2668. doi: 10.1158/0008-5472.CAN-18-2460.

PMID:
    30914430
    [PubMed - in process]
Related citations


Clinical outcomes after isolated pelvic failure in cervical cancer patients treated with definitive radiation.
Lin AJ, Ma S, Markovina S, Schwarz J, Mutch DG, Powell MA, Grigsby PW
Gynecol Oncol. 2019 Mar 21; pii: S0090-8258(19)30297-5. doi: 10.1016/j.ygyno.2019.03.104.

PMID:
    30905434
    [PubMed - as supplied by publisher]
Related citations


p5RHH nanoparticle-mediated delivery of AXL siRNA inhibits metastasis of ovarian and uterine cancer cells in mouse xenografts.
Mills KA, Quinn JM, Roach ST, Palisoul M, Nguyen M, Noia H, Guo L, Fazal J, Mutch DG, Wickline SA, Pan H, Fuh KC
Sci Rep. 2019 Mar 18; 9(1)4762. doi: 10.1038/s41598-019-41122-3.

PMID:
    30886159
    [PubMed - in process]
Related citations


Wound Complication Rates After Vulvar Excisions for Premalignant Lesions.
Mullen MM, Merfeld EC, Palisoul ML, Massad LS, Woolfolk C, Powell MA, Mutch DG, Thaker PH, Hagemann AR, Kuroki LM
Obstet Gynecol. 2019 Apr; 133(4)658-665. doi: 10.1097/AOG.0000000000003185.

PMID:
    30870300
    [PubMed - in process]
Related citations


Targeted metabolomic profiling of low and high grade serous epithelial ovarian cancer tissues: a pilot study.
Garg G, Yilmaz A, Kumar P, Turkoglu O, Mutch DG, Powell MA, Rosen B, Bahado-Singh RO, Graham SF
Metabolomics. 2018 Nov 24; 14(12)154. doi: 10.1007/s11306-018-1448-3.

PMID:
    30830441
    [PubMed - in process]
Related citations


GOG 8020/210: Risk stratification of lymph node metastasis, disease progression and survival using single nucleotide polymorphisms in endometrial cancer: An NRG oncology/gynecologic oncology group study.
Brooks RA, Tritchler DS, Darcy KM, Lankes HA, Salani R, Sperduto P, Guntupalli S, DiSilvestro P, Kesterson J, Olawaiye AB, Moxley K, Waggoner S, Santin A, Rader JS, Kizer NT, Thaker PH, Powell MA, Mutch DG, Birrer MJ, Goodfellow PJ
Gynecol Oncol. 2019 May; 153(2)335-342. doi: 10.1016/j.ygyno.2019.02.028.

PMID:
    30827726
    [PubMed - in process]
Related citations


Continuous epidural infusion in gynecologic oncology patients undergoing exploratory laparotomy: The new standard for decreased postoperative pain and opioid use.
Huepenbecker SP, Cusworth SE, Kuroki LM, Lu P, Samen CDK, Woolfolk C, Deterding R, Wan L, Helsten DL, Bottros M, Mutch DG, Powell MA, Massad LS, Thaker PH
Gynecol Oncol. 2019 May; 153(2)356-361. doi: 10.1016/j.ygyno.2019.02.017.

PMID:
    30798950
    [PubMed - in process]
Related citations


Inpatient management of hypercalcemia portends a poor prognosis among gynecologic oncology patients: A trigger to initiate hospice care?
Cripe JC, Buchanan TR Jr, Wan L, Hagemann AR, McCourt CK, Massad LS, Fuh KC, Mutch DG, Powell MA, Thaker PH, Kuroki LM
Gynecol Oncol Rep. 2019 May; 281-5. doi: 10.1016/j.gore.2019.01.005.

PMID:
    30733991
    [PubMed]
Related citations


Endometrial Tumor Immune Response: Predictive Biomarker of Response to Immunotherapy.
Mullen MM, Mutch DG
Clin Cancer Res. 2019 Apr 15; 25(8)2366-2368. doi: 10.1158/1078-0432.CCR-18-4122.

PMID:
    30692101
    [PubMed - in process]
Related citations


Association between body mass index and surgical menopausal symptoms in patients with early stage endometrial cancer.
Cripe JC, Buchanan TR Jr, Kuroki LM, Wan L, Mills KA, Massad L, Hagemann AR, Fuh KC, Mutch DG, Powell MA, Matsuo K, Thaker PH
Gynecol Oncol. 2019 Apr; 153(1)123-126. doi: 10.1016/j.ygyno.2019.01.009.

PMID:
    30651188
    [PubMed - indexed for MEDLINE]
Related citations


Nomogram for Predicting Individual Survival After Recurrence of Advanced-Stage, High-Grade Ovarian Carcinoma.
Rose PG, Java JJ, Salani R, Geller MA, Secord AA, Tewari KS, Bender DP, Mutch DG, Friedlander ML, Van Le L, Method MW, Hamilton CA, Lee RB, Wenham RM, Guntupalli SR, Markman M, Muggia FM, Armstrong DK, Bookman MA, Burger RA, Copeland LJ
Obstet Gynecol. 2019 Feb; 133(2)245-254. doi: 10.1097/AOG.0000000000003086.

PMID:
    30633128
    [PubMed - in process]
Related citations


Postpartum salpingectomy: a procedure whose time has come.
Zamorano AS, Mutch DG
Am J Obstet Gynecol. 2019 Jan; 220(1)8-9. doi: 10.1016/j.ajog.2018.09.041.

PMID:
    30591122
    [PubMed - in process]
Related citations


A randomized phase II study of cabozantinib versus weekly paclitaxel in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer: An NRG Oncology/Gynecologic Oncology Group study.
Matulonis UA, Sill MW, Makker V, Mutch DG, Carlson JW, Darus CJ, Mannel RS, Bender DP, Crane EK, Aghajanian C
Gynecol Oncol. 2019 Mar; 152(3)548-553. doi: 10.1016/j.ygyno.2018.12.008.

PMID:
    30587441
    [PubMed - indexed for MEDLINE]
Related citations


Obesity counseling in obstetrics and gynecology: provider perceptions and barriers.
Huepenbecker SP, Wan L, Leon A, Rosen D, Hoff J, Kuroki LM, Fuh KC, Powell MA, Mutch DG, Colditz GA, Hagemann AR
Gynecol Oncol Rep. 2019 Feb; 2731-34. doi: 10.1016/j.gore.2018.12.001.

PMID:
    30582746
    [PubMed]
Related citations


Therapeutic Inhibition of the Receptor Tyrosine Kinase AXL Improves Sensitivity to Platinum and Taxane in Ovarian Cancer.
Quinn JM, Greenwade MM, Palisoul ML, Opara G, Massad K, Guo L, Zhao P, Beck-Noia H, Hagemann IS, Hagemann AR, McCourt CK, Thaker PH, Powell MA, Mutch DG, Fuh KC
Mol Cancer Ther. 2019 Feb; 18(2)389-398. doi: 10.1158/1535-7163.MCT-18-0537.

PMID:
    30478151
    [PubMed - in process]
Related citations


Intensity Modulated Radiation Therapy and Image-Guided Adapted Brachytherapy for Cervix Cancer.
Lin AJ, Kidd E, Dehdashti F, Siegel BA, Mutic S, Thaker PH, Massad LS, Powell MA, Mutch DG, Markovina S, Schwarz J, Grigsby PW
Int J Radiat Oncol Biol Phys. 2019 Apr 1; 103(5)1088-1097. doi: 10.1016/j.ijrobp.2018.11.012.

PMID:
    30445171
    [PubMed - in process]
Related citations


Adipokines Deregulate Cellular Communication via Epigenetic Repression of <i>Gap Junction</i> Loci in Obese Endometrial Cancer.
Polusani SR, Huang YW, Huang G, Chen CW, Wang CM, Lin LL, Osmulski P, Lucio ND, Liu L, Hsu YT, Zhou Y, Lin CL, Aguilera-Barrantes I, Valente PT, Kost ER, Chen CL, Shim EY, Lee SE, Ruan J, Gaczynska ME, Yan P, Goodfellow PJ, Mutch DG, Jin VX, Nicholson BJ, Huang TH, Kirma NB
Cancer Res. 2019 Jan 1; 79(1)196-208. doi: 10.1158/0008-5472.CAN-18-1615.

PMID:
    30389702
    [PubMed - in process]
Related citations

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians and health professionals are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians and health professionals work collaboratively with pharmaceutical, medical device or other medical care related companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our physicians and health professionals have an ownership or potential ownership interest in a commercial company; and/or are paid by a commercial company to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians or health professionals must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this website, physicians and health professionals earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following financial interests during calendar year 2018:

Company Name: Clovis Oncology

Royalties:

Equity: No

Consulting/Advisory Board:

Speaker Fees: $10,000 - $19,999

Reporting Date: May 01, 2019