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David D. Limbrick, MD, PhD

Chief, Pediatric Neurosurgery
Professor, Neurological Surgery
Professor, Pediatrics
Neurosurgeon-in-Chief, St. Louis Children's Hospital

Specialty Areas

Pediatric Neurosurgery
Pediatric Epilepsy
Brain Tumors - Pediatric
Spine Surgery - Neurosurgery

Board Certifications

Neurological Surgery

Hospital Affiliations

St. Louis Children's Hospital
Barnes-Jewish Hospital

Areas of Clinical Interest

Pediatric neurosurgery, epilepsy surgery, neuro-endoscopy, hydrocephalus, pediatric brain tumors, deep brain stimulation, radiosurgery, pediatric spine.

  • Maps & Directions
  • Education
  • Publication & Research
  • In the News

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Office Phone: (314) 454-4630
Fax: (314) 454-2818

Education

Education

Residency: Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri 2007
Medical Degree: Medical College of Virginia, Virginia Commonwealth University 2001
Ph.D.: Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University 2000
Fellowship: Pediatric Neurosurgery, St. Louis Children's Hospital, St. Louis, Missouri 2007
B.S.: Biology, College of William and Mary, Williamsburg, Virginia 1992
M.S.: Physiology, Medical College of Virginia, Virginia Commonwealth University 1995

Publication & Research

Publication & Research

Growth and alignment of the pediatric subaxial cervical spine following rigid instrumentation and fusion: a multicenter study of the Pediatric Craniocervical Society.
Goldstein HE, Neira JA, Banu M, Aldana PR, Braga BP, Brockmeyer DL, DiLuna ML, Fulkerson DH, Hankinson TC, Jea AH, Lew SM, Limbrick DD, Martin J, Pahys JM, Rodriguez LF, Rozzelle CJ, Tuite GF, Wetjen NM, Anderson RCE
J Neurosurg Pediatr. 2018 Apr 20; 1-8. doi: 10.3171/2018.1.PEDS17551.

PMID:
    29676682
    [PubMed - as supplied by publisher]
Related citations


Resting state signal latency predicts laterality in pediatric medically refractory temporal lobe epilepsy.
Shah MN, Mitra A, Goyal MS, Snyder AZ, Zhang J, Shimony JS, Limbrick DD, Raichle ME, Smyth MD
Childs Nerv Syst. 2018 May; 34(5)901-910. doi: 10.1007/s00381-018-3770-5.

PMID:
    29511809
    [PubMed - in process]
Related citations


MRI-Guided Interstitial Laser Ablation for Intracranial Lesions: A Large Single-Institution Experience of 133 Cases.
Kamath AA, Friedman DD, Hacker CD, Smyth MD, Limbrick DD Jr, Kim AH, Hawasli AH, Leuthardt EC
Stereotact Funct Neurosurg. 2017; 95(6)417-428. doi: 10.1159/000485387.

PMID:
    29339639
    [PubMed - in process]
Related citations


An 8-Year-Old Girl with A Supratentorial Mass.
Schwetye KE, Gauvain K, Rodriguez D, Cottrell C, Limbrick DD Jr, Schmidt RE, Dahiya S
Brain Pathol. 2018 Jan; 28(1)125-126. doi: 10.1111/bpa.12576.

PMID:
    29265627
    [PubMed - in process]
Related citations


Chemokine and cytokine levels in the lumbar cerebrospinal fluid of preterm infants with post-hemorrhagic hydrocephalus.
Habiyaremye G, Morales DM, Morgan CD, McAllister JP, CreveCoeur TS, Han RH, Gabir M, Baksh B, Mercer D, Limbrick DD Jr
Fluids Barriers CNS. 2017 Dec 12; 14(1)35. doi: 10.1186/s12987-017-0083-0.

PMID:
    29228970
    [PubMed - in process]
Related citations


On the role of the corpus callosum in interhemispheric functional connectivity in humans.
Roland JL, Snyder AZ, Hacker CD, Mitra A, Shimony JS, Limbrick DD, Raichle ME, Smyth MD, Leuthardt EC
Proc Natl Acad Sci U S A. 2017 Dec 12; 114(50)13278-13283. doi: 10.1073/pnas.1707050114.

PMID:
    29183973
    [PubMed - in process]
Related citations


Resting-state functional magnetic resonance imaging for surgical planning in pediatric patients: a preliminary experience.
Roland JL, Griffin N, Hacker CD, Vellimana AK, Akbari SH, Shimony JS, Smyth MD, Leuthardt EC, Limbrick DD Jr
J Neurosurg Pediatr. 2017 Dec; 20(6)583-590. doi: 10.3171/2017.6.PEDS1711.

PMID:
    28960172
    [PubMed - indexed for MEDLINE]
Related citations


Abstracts from Hydrocephalus 2016.
Adam A, Robison J, Lu J, Jose R, Badran N, Vivas-Buitrago T, Rigamonti D, Sattar A, Omoush O, Hammad M, Dawood M, Maghaslah M, Belcher T, Carson K, Hoffberger J, Jusué Torres I, Foley S, Yasar S, Thai QA, Wemmer J, Klinge P, Al-Mutawa L, Al-Ghamdi H, Carson KA, Asgari M, de Zélicourt D, Kurtcuoglu V, Garnotel S, Salmon S, Balédent O, Lokossou A, Page G, Balardy L, Czosnyka Z, Payoux P, Schmidt EA, Zitoun M, Sevestre MA, Alperin N, Baudracco I, Craven C, Matloob S, Thompson S, Haylock Vize P, Thorne L, Watkins LD, Toma AK, Bechter K, Pong AC, Jugé L, Bilston LE, Cheng S, Bradley W, Hakim F, Ramón JF, Cárdenas MF, Davidson JS, García C, González D, Bermúdez S, Useche N, Mejía JA, Mayorga P, Cruz F, Martinez C, Matiz MC, Vallejo M, Ghotme K, Soto HA, Riveros D, Buitrago A, Mora M, Murcia L, Bermudez S, Cohen D, Dasgupta D, Curtis C, Domínguez L, Remolina AJ, Grijalba MA, Whitehouse KJ, Edwards RJ, Eleftheriou A, Lundin F, Fountas KN, Kapsalaki EZ, Smisson HF, Robinson JS, Fritsch MJ, Arouk W, Garzon M, Kang M, Sandhu K, Baghawatti D, Aquilina K, James G, Thompson D, Gehlen M, Schmid Daners M, Eklund A, Malm J, Gomez D, Guerra M, Jara M, Flores M, Vío K, Moreno I, Rodríguez S, Ortega E, Rodríguez EM, McAllister JP, Guerra MM, Morales DM, Sival D, Jimenez A, Limbrick DD, Ishikawa M, Yamada S, Yamamoto K, Junkkari A, Häyrinen A, Rauramaa T, Sintonen H, Nerg O, Koivisto AM, Roine RP, Viinamäki H, Soininen H, Luikku A, Jääskeläinen JE, Leinonen V, Kehler U, Lilja-Lund O, Kockum K, Larsson EM, Riklund K, Söderström L, Hellström P, Laurell K, Kojoukhova M, Sutela A, Vanninen R, Vanha KI, Timonen M, Rummukainen J, Korhonen V, Helisalmi S, Solje E, Remes AM, Huovinen J, Paananen J, Hiltunen M, Kurki M, Martin B, Loth F, Luciano M, Luikku AJ, Hall A, Herukka SK, Mattila J, Lötjönen J, Alafuzoff I, Jurjević I, Miyajima M, Nakajima M, Murai H, Shin T, Kawaguchi D, Akiba C, Ogino I, Karagiozov K, Arai H, Reis RC, Teixeira MJ, Valêncio CG, da Vigua D, Almeida-Lopes L, Mancini MW, Pinto FCG, Maykot RH, Calia G, Tornai J, Silvestre SSS, Mendes G, Sousa V, Bezerra B, Dutra P, Modesto P, Oliveira MF, Petitto CE, Pulhorn H, Chandran A, McMahon C, Rao AS, Jumaly M, Solomon D, Moghekar A, Relkin N, Hamilton M, Katzen H, Williams M, Bach T, Zuspan S, Holubkov R, Rigamonti A, Clemens G, Sharkey P, Sanyal A, Sankey E, Rigamonti K, Naqvi S, Hung A, Schmidt E, Ory-Magne F, Gantet P, Guenego A, Januel AC, Tall P, Fabre N, Mahieu L, Cognard C, Gray L, Buttner-Ennever JA, Takagi K, Onouchi K, Thompson SD, Thorne LD, Tully HM, Wenger TL, Kukull WA, Doherty D, Dobyns WB, Moran D, Vakili S, Patel MA, Elder B, Goodwin CR, Crawford JA, Pletnikov MV, Xu J, Blitz A, Herzka DA, Guerrero-Cazares H, Quiñones-Hinojosa A, Mori S, Saavedra P, Treviño H, Maitani K, Ziai WC, Eslami V, Nekoovaght-Tak S, Dlugash R, Yenokyan G, McBee N, Hanley DF
Fluids Barriers CNS. 2017 Jun 7; 14(Suppl 1)15. doi: 10.1186/s12987-017-0054-5.

PMID:
    28929972
    [PubMed - in process]
Related citations


Time-to-event analysis of surgically treated posthemorrhagic hydrocephalus in preterm infants: a single-institution retrospective study.
Han RH, Berger D, Gabir M, Baksh BS, Morales DM, Mathur AM, Smyser CD, Strahle JM, Limbrick DD Jr
Childs Nerv Syst. 2017 Nov; 33(11)1917-1926. doi: 10.1007/s00381-017-3588-6.

PMID:
    28884229
    [PubMed - in process]
Related citations


Endoscopic Third Ventriculostomy in Patients with Neurofibromatosis Type 1: A Multicenter International Experience.
Roth J, Ber R, Wisoff JH, Hidalgo ET, Limbrick DD, Berger DS, Thomale UW, Schulz M, Cinalli G, Santoro C, Constantini S
World Neurosurg. 2017 Nov; 107623-629. doi: 10.1016/j.wneu.2017.08.053.

PMID:
    28842232
    [PubMed - indexed for MEDLINE]
Related citations


Cerebrospinal Fluid Biomarkers of Pediatric Hydrocephalus.
Limbrick DD Jr, Castaneyra-Ruiz L, Han RH, Berger D, McAllister JP, Morales DM
Pediatr Neurosurg. 2017; 52(6)426-435. doi: 10.1159/000477175.

PMID:
    28797007
    [PubMed - in process]
Related citations


Applications of a robotic stereotactic arm for pediatric epilepsy and neurooncology surgery.
Miller BA, Salehi A, Limbrick DD Jr, Smyth MD
J Neurosurg Pediatr. 2017 Oct; 20(4)364-370. doi: 10.3171/2017.5.PEDS1782.

PMID:
    28777037
    [PubMed - indexed for MEDLINE]
Related citations


Analysis and interrater reliability of pB-C2 using MRI and CT: data from the Park-Reeves Syringomyelia Research Consortium on behalf of the Pediatric Craniocervical Society.
Hankinson TC, Tuite GF, Moscoso DI, Robinson LC, Torner JC, Limbrick DD Jr, Park TS, Anderson RCE
J Neurosurg Pediatr. 2017 Aug; 20(2)170-175. doi: 10.3171/2017.3.PEDS16604.

PMID:
    28524792
    [PubMed - indexed for MEDLINE]
Related citations


Ventricular Zone Disruption in Human Neonates With Intraventricular Hemorrhage.
McAllister JP, Guerra MM, Ruiz LC, Jimenez AJ, Dominguez-Pinos D, Sival D, den Dunnen W, Morales DM, Schmidt RE, Rodriguez EM, Limbrick DD
J Neuropathol Exp Neurol. 2017 May 1; 76(5)358-375. doi: 10.1093/jnen/nlx017.

PMID:
    28521038
    [PubMed - indexed for MEDLINE]
Related citations


Shunting outcomes in posthemorrhagic hydrocephalus: results of a Hydrocephalus Clinical Research Network prospective cohort study.
Wellons JC 3rd, Shannon CN, Holubkov R, Riva-Cambrin J, Kulkarni AV, Limbrick DD Jr, Whitehead W, Browd S, Rozzelle C, Simon TD, Tamber MS, Oakes WJ, Drake J, Luerssen TG, Kestle J, Hydrocephalus Clinical Research Network.
J Neurosurg Pediatr. 2017 Jul; 20(1)19-29. doi: 10.3171/2017.1.PEDS16496.

PMID:
    28452657
    [PubMed - indexed for MEDLINE]
Related citations


Electrophysiological Sequelae of Hemispherotomy in Ipsilateral Human Cortex.
Hawasli AH, Chacko R, Szrama NP, Bundy DT, Pahwa M, Yarbrough CK, Dlouhy BJ, Limbrick DD, Barbour DL, Smyth MD, Leuthardt EC
Front Hum Neurosci. 2017; 11149. doi: 10.3389/fnhum.2017.00149.

PMID:
    28424599
    [PubMed]
Related citations


Cerebrospinal fluid biomarkers of infantile congenital hydrocephalus.
Limbrick DD Jr, Baksh B, Morgan CD, Habiyaremye G, McAllister JP 2nd, Inder TE, Mercer D, Holtzman DM, Strahle J, Wallendorf MJ, Morales DM
PLoS One. 2017; 12(2)e0172353. doi: 10.1371/journal.pone.0172353.

PMID:
    28212403
    [PubMed - indexed for MEDLINE]
Related citations


Development and Internal Validation of a Clinical Risk Score for Treating Children With Mild Head Trauma and Intracranial Injury.
Greenberg JK, Yan Y, Carpenter CR, Lumba-Brown A, Keller MS, Pineda JA, Brownson RC, Limbrick DD
JAMA Pediatr. 2017 Apr 1; 171(4)342-349. doi: 10.1001/jamapediatrics.2016.4520.

PMID:
    28192567
    [PubMed - indexed for MEDLINE]
Related citations


Ventricular catheter entry site and not catheter tip location predicts shunt survival: a secondary analysis of 3 large pediatric hydrocephalus studies.
Whitehead WE, Riva-Cambrin J, Kulkarni AV, Wellons JC 3rd, Rozzelle CJ, Tamber MS, Limbrick DD Jr, Browd SR, Naftel RP, Shannon CN, Simon TD, Holubkov R, Illner A, Cochrane DD, Drake JM, Luerssen TG, Oakes WJ, Kestle JR,  for the Hydrocephalus Clinical Research Network.
J Neurosurg Pediatr. 2017 Feb; 19(2)157-167. doi: 10.3171/2016.8.PEDS16229.

PMID:
    27813457
    [PubMed - indexed for MEDLINE]
Related citations


Hemispherotomy in children with electrical status epilepticus of sleep.
Jeong A, Strahle J, Vellimana AK, Limbrick DD Jr, Smyth MD, Bertrand M
J Neurosurg Pediatr. 2017 Jan; 19(1)56-62. doi: 10.3171/2016.8.PEDS16319.

PMID:
    27791702
    [PubMed - indexed for MEDLINE]
Related citations

In the News

Areas of Research Interest

Cerebrospinal fluid physiology and neonatal hydrocephalus.