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David D. Limbrick, MD, PhD

Chief, Pediatric Neurosurgery
Associate Professor, Neurological Surgery
Associate Professor, Pediatrics
Neurosurgeon-in-Chief, St. Louis Children's Hospital

Specialty Areas

Pediatric Neurosurgery
Pediatric Epilepsy
Brain Tumors - Pediatric

Board Certifications

Neurological Surgery

Hospital Affiliations

St. Louis Children's Hospital
Barnes-Jewish Hospital

Areas of Clinical Interest

Pediatric neurosurgery, epilepsy surgery, neuro-endoscopy, hydrocephalus, pediatric brain tumors, deep brain stimulation, radiosurgery, pediatric spine.

  • Maps & Directions
  • Education
  • Publication & Research
  • In the News

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Office Phone: (314) 454-4630
Fax: (314) 454-2818

Education

Education

Residency: Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri 2007
Medical Degree: Medical College of Virginia, Virginia Commonwealth University 2001
Ph.D.: Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University 2000
Fellowship: Pediatric Neurosurgery, St. Louis Children's Hospital, St. Louis, Missouri 2007
B.S.: Biology, College of William and Mary, Williamsburg, Virginia 1992
M.S.: Physiology, Medical College of Virginia, Virginia Commonwealth University 1995

Publication & Research

Publication & Research

Changes of White Matter Diffusion Anisotropy in Response to a 6-Week iPad Application-Based Occupational Therapy Intervention in Children with Surgically Treated Hydrocephalus: A Pilot Study.
Yuan W, Harpster K, Jones BV, Shimony JS, McKinstry RC, Weckherlin N, Powell SS, Barnard H, Engsberg J, Kadis DS, Dodd J, Altaye M, Limbrick DD, Holland SK, Simpson SM, Bidwell S, Mangano FT
Neuropediatrics. 2016 Jul 20;

PMID:
    27438376
    [PubMed - as supplied by publisher]
Related citations


183 A Clinical Risk Score for Managing Children With Glasgow Coma Scale 13 to 15 Head Injuries and Intracranial Injury.
Greenberg JK, Yan Y, Carpenter C, Lumba-Brown A, Keller MS, Pineda JA, Brownson RC, Limbrick DD
Neurosurgery. 2016 Aug; 63 Suppl 1172-3. doi: 10.1227/01.neu.0000489752.67038.e7.

PMID:
    27399462
    [PubMed - in process]
Related citations


Predicting blunt cerebrovascular injury in pediatric trauma: Validation of the "Utah Score".
Ravindra VM, Bollo R, Sivakumar W, Akbari H, Naftel RP, Limbrick DD, Jea A, Gannon SR, Shannon C, Birkas Y, Yang GL, Prather CT, Kestle J, Riva-Cambrin J
J Neurotrauma. 2016 Jun 13;

PMID:
    27297774
    [PubMed - as supplied by publisher]
Related citations


Endoscopic third ventriculostomy in children: prospective, multicenter results from the Hydrocephalus Clinical Research Network.
Kulkarni AV, Riva-Cambrin J, Holubkov R, Browd SR, Cochrane DD, Drake JM, Limbrick DD, Rozzelle CJ, Simon TD, Tamber MS, Wellons JC 3rd, Whitehead WE, Kestle JR, Hydrocephalus Clinical Research Network
J Neurosurg Pediatr. 2016 Jun 3; 1-7.

PMID:
    27258593
    [PubMed - as supplied by publisher]
Related citations


Diffusion tensor imaging study of pediatric patients with congenital hydrocephalus: 1-year postsurgical outcomes.
Mangano FT, Altaye M, McKinstry RC, Shimony JS, Powell SK, Phillips JM, Barnard H, Limbrick DD Jr, Holland SK, Jones BV, Dodd J, Simpson S, Mercer D, Rajagopal A, Bidwell S, Yuan W
J Neurosurg Pediatr. 2016 May 20; 1-14.

PMID:
    27203134
    [PubMed - as supplied by publisher]
Related citations


Natural history of colloid cysts of the third ventricle.
Beaumont TL, Limbrick DD Jr, Rich KM, Wippold FJ 2nd, Dacey RG Jr
J Neurosurg. 2016 Mar 11; 1-11.

PMID:
    26967781
    [PubMed - as supplied by publisher]
Related citations


Chiari malformation Type I surgery in pediatric patients. Part 1: validation of an ICD-9-CM code search algorithm.
Ladner TR, Greenberg JK, Guerrero N, Olsen MA, Shannon CN, Yarbrough CK, Piccirillo JF, Anderson RC, Feldstein NA, Wellons JC 3rd, Smyth MD, Park TS, Limbrick DD Jr
J Neurosurg Pediatr. 2016 May; 17(5)519-24. doi: 10.3171/2015.10.PEDS15370.

PMID:
    26799412
    [PubMed - in process]
Related citations


Chiari malformation Type I surgery in pediatric patients. Part 2: complications and the influence of comorbid disease in California, Florida, and New York.
Greenberg JK, Olsen MA, Yarbrough CK, Ladner TR, Shannon CN, Piccirillo JF, Anderson RC, Wellons JC 3rd, Smyth MD, Park TS, Limbrick DD Jr
J Neurosurg Pediatr. 2016 May; 17(5)525-32. doi: 10.3171/2015.10.PEDS15369.

PMID:
    26799408
    [PubMed - in process]
Related citations


A new Hydrocephalus Clinical Research Network protocol to reduce cerebrospinal fluid shunt infection.
Kestle JR, Holubkov R, Douglas Cochrane D, Kulkarni AV, Limbrick DD Jr, Luerssen TG, Jerry Oakes W, Riva-Cambrin J, Rozzelle C, Simon TD, Walker ML, Wellons JC 3rd, Browd SR, Drake JM, Shannon CN, Tamber MS, Whitehead WE, Hydrocephalus Clinical Research Network
J Neurosurg Pediatr. 2016 Apr; 17(4)391-6. doi: 10.3171/2015.8.PEDS15253.

PMID:
    26684763
    [PubMed - in process]
Related citations


Risk factors for shunt malfunction in pediatric hydrocephalus: a multicenter prospective cohort study.
Riva-Cambrin J, Kestle JR, Holubkov R, Butler J, Kulkarni AV, Drake J, Whitehead WE, Wellons JC 3rd, Shannon CN, Tamber MS, Limbrick DD Jr, Rozzelle C, Browd SR, Simon TD, Hydrocephalus Clinical Research Network
J Neurosurg Pediatr. 2016 Apr; 17(4)382-90. doi: 10.3171/2015.6.PEDS14670.

PMID:
    26636251
    [PubMed - in process]
Related citations


Chiari I Malformation: Adult and Pediatric Considerations.
Leonard JR, Limbrick DD Jr
Neurosurg Clin N Am. 2015 Oct; 26(4)xiii-xiv. doi: 10.1016/j.nec.2015.07.002.

PMID:
    26408069
    [PubMed - in process]
Related citations


In Reply: Chiari Severity Index: A Novel Grading System Intended for Preoperative Counseling.
Greenberg JK, Yarbrough CK, Radmanesh A, Godzik J, Yu M, Jeffe DB, Smyth MD, Park TS, Piccirillo JF, Limbrick DD Jr
Neurosurgery. 2015 Nov; 77(5)E842. doi: 10.1227/NEU.0000000000000936.

PMID:
    26258944
    [PubMed - indexed for MEDLINE]
Related citations


Hydrocephalus in children.
Kahle KT, Kulkarni AV, Limbrick DD Jr, Warf BC
Lancet. 2016 Feb 20; 387(10020)788-99. doi: 10.1016/S0140-6736(15)60694-8.

PMID:
    26256071
    [PubMed - indexed for MEDLINE]
Related citations


Abnormal structural connectivity in the brain networks of children with hydrocephalus.
Yuan W, Holland SK, Shimony JS, Altaye M, Mangano FT, Limbrick DD, Jones BV, Nash T, Rajagopal A, Simpson S, Ragan D, McKinstry RC
Neuroimage Clin. 2015; 8483-92. doi: 10.1016/j.nicl.2015.04.015.

PMID:
    26106573
    [PubMed - indexed for MEDLINE]
Related citations


An update on research priorities in hydrocephalus: overview of the third National Institutes of Health-sponsored symposium "Opportunities for Hydrocephalus Research: Pathways to Better Outcomes".
McAllister JP 2nd, Williams MA, Walker ML, Kestle JR, Relkin NR, Anderson AM, Gross PH, Browd SR, Hydrocephalus Symposium Expert Panel
J Neurosurg. 2015 Dec; 123(6)1427-38. doi: 10.3171/2014.12.JNS132352.

PMID:
    26090833
    [PubMed - indexed for MEDLINE]
Related citations


Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Part 4: Cerebrospinal fluid shunt or endoscopic third ventriculostomy for the treatment of hydrocephalus in children.
Limbrick DD Jr, Baird LC, Klimo P Jr, Riva-Cambrin J, Flannery AM, Pediatric Hydrocephalus Systematic Review and Evidence-Based Guidelines Task Force
J Neurosurg Pediatr. 2014 Nov; 14 Suppl 130-4. doi: 10.3171/2014.7.PEDS14324.

PMID:
    25988780
    [PubMed - indexed for MEDLINE]
Related citations


Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Part 2: Management of posthemorrhagic hydrocephalus in premature infants.
Mazzola CA, Choudhri AF, Auguste KI, Limbrick DD Jr, Rogido M, Mitchell L, Flannery AM, Pediatric Hydrocephalus Systematic Review and Evidence-Based Guidelines Task Force
J Neurosurg Pediatr. 2014 Nov; 14 Suppl 18-23. doi: 10.3171/2014.7.PEDS14322.

PMID:
    25988778
    [PubMed - indexed for MEDLINE]
Related citations


Foreword: Pediatric hydrocephalus: systematic literature review and evidence-based guidelines.
Flannery AM, Mazzola CA, Klimo P Jr, Duhaime AC, Baird LC, Tamber MS, Limbrick DD Jr, Nikas DC, Kemp J, Post AF, Auguste KI, Choudhri AF, Mitchell LS, Buffa D
J Neurosurg Pediatr. 2014 Nov; 14 Suppl 11-2. doi: 10.3171/2014.8.PEDS14426.

PMID:
    25988776
    [PubMed - indexed for MEDLINE]
Related citations


Comparison of spinal deformity in children with Chiari I malformation with and without syringomyelia: matched cohort study.
Godzik J, Dardas A, Kelly MP, Holekamp TF, Lenke LG, Smyth MD, Park TS, Leonard JR, Limbrick DD
Eur Spine J. 2016 Feb; 25(2)619-26. doi: 10.1007/s00586-015-4011-1.

PMID:
    25981206
    [PubMed - in process]
Related citations


Risks and outcomes of spinal deformity surgery in Chiari malformation, Type 1, with syringomyelia versus adolescent idiopathic scoliosis.
Godzik J, Holekamp TF, Limbrick DD, Lenke LG, Park TS, Ray WZ, Bridwell KH, Kelly MP
Spine J. 2015 Sep 1; 15(9)2002-8. doi: 10.1016/j.spinee.2015.04.048.

PMID:
    25959792
    [PubMed - indexed for MEDLINE]
Related citations

In the News

Areas of Research Interest

Cerebrospinal fluid physiology and neonatal hydrocephalus.