Patient Portal

David D. Limbrick, MD, PhD

Chief, Pediatric Neurosurgery
Professor, Neurological Surgery
Professor, Pediatrics
Neurosurgeon-in-Chief, St. Louis Children's Hospital

Specialty Areas

Pediatric Neurosurgery
Pediatric Epilepsy
Brain Tumors - Pediatric
Spine Surgery - Neurosurgery

Board Certifications

Neurological Surgery

Hospital Affiliations

St. Louis Children's Hospital
Barnes-Jewish Hospital

Areas of Clinical Interest

Pediatric neurosurgery, epilepsy surgery, neuro-endoscopy, hydrocephalus, pediatric brain tumors, deep brain stimulation, radiosurgery, pediatric spine.

  • Maps & Directions
  • Education
  • Publication & Research
  • In the News

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Office Phone: (314) 454-4630
Fax: (314) 454-2818

Education

Education

Residency: Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri 2007
Medical Degree: Medical College of Virginia, Virginia Commonwealth University 2001
Ph.D.: Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University 2000
Fellowship: Pediatric Neurosurgery, St. Louis Children's Hospital, St. Louis, Missouri 2007
B.S.: Biology, College of William and Mary, Williamsburg, Virginia 1992
M.S.: Physiology, Medical College of Virginia, Virginia Commonwealth University 1995

Publication & Research

Publication & Research

Development of best practices to minimize wound complications after complex tethered spinal cord surgery: a modified Delphi study.
Alexiades NG, Ahn ES, Blount JP, Brockmeyer DL, Browd SR, Grant GA, Heuer GG, Hankinson TC, Iskandar BJ, Jea A, Krieger MD, Leonard JR, Limbrick DD Jr, Maher CO, Proctor MR, Sandberg DI, Wellons JC 3rd, Shao B, Feldstein NA, Anderson RCE
J Neurosurg Pediatr. 2018 Sep 14; 1-9. doi: 10.3171/2018.6.PEDS18243.

PMID:
    30215584
    [PubMed - as supplied by publisher]
Related citations


Treatment of pediatric intracranial aneurysms: case series and meta-analysis.
Yasin JT, Wallace AN, Madaelil TP, Osbun JW, Moran CJ, Cross DT, Limbrick DD, Zipfel GJ, Dacey RG, Kansagra AP
J Neurointerv Surg. 2018 Aug 12; pii: neurintsurg-2018-014001. doi: 10.1136/neurintsurg-2018-014001.

PMID:
    30100557
    [PubMed - as supplied by publisher]
Related citations


Widely Metastatic Choroid Plexus Carcinoma Associated with Novel TP53 Somatic Mutation.
Baksh BS, Sinha N, Salehi A, Han RH, Miller BA, Dahiya S, Gauvain KM, Limbrick DD Jr
World Neurosurg. 2018 Nov; 119233-236. doi: 10.1016/j.wneu.2018.07.284.

PMID:
    30099178
    [PubMed - in process]
Related citations


Neonatal brain injury and aberrant connectivity.
Smyser CD, Wheelock MD, Limbrick DD Jr, Neil JJ
Neuroimage. 2018 Jul 27; pii: S1053-8119(18)30672-4. doi: 10.1016/j.neuroimage.2018.07.057.

PMID:
    30059733
    [PubMed - as supplied by publisher]
Related citations


Blood Exposure Causes Ventricular Zone Disruption and Glial Activation In Vitro.
Castaneyra-Ruiz L, Morales DM, McAllister JP, Brody SL, Isaacs AM, Strahle JM, Dahiya SM, Limbrick DD
J Neuropathol Exp Neurol. 2018 Sep 1; 77(9)803-813. doi: 10.1093/jnen/nly058.

PMID:
    30032242
    [PubMed - in process]
Related citations


Predictors of mortality for preterm infants with intraventricular hemorrhage: a population-based study.
Han RH, McKinnon A, CreveCoeur TS, Baksh BS, Mathur AM, Smyser CD, Strahle JM, Olsen MA, Limbrick DD Jr
Childs Nerv Syst. 2018 Jul 9; doi: 10.1007/s00381-018-3897-4.

PMID:
    29987373
    [PubMed - as supplied by publisher]
Related citations


De Novo Mutation in Genes Regulating Neural Stem Cell Fate in Human Congenital Hydrocephalus.
Furey CG, Choi J, Jin SC, Zeng X, Timberlake AT, Nelson-Williams C, Mansuri MS, Lu Q, Duran D, Panchagnula S, Allocco A, Karimy JK, Khanna A, Gaillard JR, DeSpenza T, Antwi P, Loring E, Butler WE, Smith ER, Warf BC, Strahle JM, Limbrick DD, Storm PB, Heuer G, Jackson EM, Iskandar BJ, Johnston JM, Tikhonova I, Castaldi C, López-Giráldez F, Bjornson RD, Knight JR, Bilguvar K, Mane S, Alper SL, Haider S, Guclu B, Bayri Y, Sahin Y, Apuzzo MLJ, Duncan CC, DiLuna ML, Günel M, Lifton RP, Kahle KT
Neuron. 2018 Jul 25; 99(2)302-314.e4. doi: 10.1016/j.neuron.2018.06.019.

PMID:
    29983323
    [PubMed - in process]
Related citations


Development of the CIDSS<sub>2</sub> Score for Children with Mild Head Trauma without Intracranial Injury.
Greenberg JK, Yan Y, Carpenter CR, Lumba-Brown A, Keller MS, Pineda JA, Brownson RC, Limbrick DD
J Neurotrauma. 2018 Nov 15; 35(22)2699-2707. doi: 10.1089/neu.2017.5324.

PMID:
    29882466
    [PubMed - in process]
Related citations


Patient and Treatment Characteristics by Infecting Organism in Cerebrospinal Fluid Shunt Infection.
Simon TD, Kronman MP, Whitlock KB, Browd SR, Holubkov R, Kestle JRW, Kulkarni AV, Langley M, Limbrick DD Jr, Luerssen TG, Oakes J, Riva-Cambrin J, Rozzelle C, Shannon CN, Tamber M, Wellons Iii JC, Whitehead WE, Mayer-Hamblett N, Hydrocephalus Clinical Research Network.
J Pediatric Infect Dis Soc. 2018 May 15; doi: 10.1093/jpids/piy035.

PMID:
    29771360
    [PubMed - as supplied by publisher]
Related citations


Growth and alignment of the pediatric subaxial cervical spine following rigid instrumentation and fusion: a multicenter study of the Pediatric Craniocervical Society.
Goldstein HE, Neira JA, Banu M, Aldana PR, Braga BP, Brockmeyer DL, DiLuna ML, Fulkerson DH, Hankinson TC, Jea AH, Lew SM, Limbrick DD, Martin J, Pahys JM, Rodriguez LF, Rozzelle CJ, Tuite GF, Wetjen NM, Anderson RCE
J Neurosurg Pediatr. 2018 Jul; 22(1)81-88. doi: 10.3171/2018.1.PEDS17551.

PMID:
    29676682
    [PubMed - in process]
Related citations


Opportunities in posthemorrhagic hydrocephalus research: outcomes of the Hydrocephalus Association Posthemorrhagic Hydrocephalus Workshop.
Koschnitzky JE, Keep RF, Limbrick DD Jr, McAllister JP 2nd, Morris JA, Strahle J, Yung YC
Fluids Barriers CNS. 2018 Mar 27; 15(1)11. doi: 10.1186/s12987-018-0096-3.

PMID:
    29587767
    [PubMed - indexed for MEDLINE]
Related citations


Resting state signal latency predicts laterality in pediatric medically refractory temporal lobe epilepsy.
Shah MN, Mitra A, Goyal MS, Snyder AZ, Zhang J, Shimony JS, Limbrick DD, Raichle ME, Smyth MD
Childs Nerv Syst. 2018 May; 34(5)901-910. doi: 10.1007/s00381-018-3770-5.

PMID:
    29511809
    [PubMed - in process]
Related citations


Prevalence, management, and outcome of problem residents among neurosurgical training programs in the United States.
Raman HS, Limbrick DD Jr, Ray WZ, Coble DW, Church S, Dacey RG Jr, Zipfel GJ
J Neurosurg. 2018 Mar 2; 1-5. doi: 10.3171/2017.8.JNS171719.

PMID:
    29498572
    [PubMed - as supplied by publisher]
Related citations


Reinfection after treatment of first cerebrospinal fluid shunt infection: a prospective observational cohort study.
Simon TD, Kronman MP, Whitlock KB, Gove NE, Mayer-Hamblett N, Browd SR, Cochrane DD, Holubkov R, Kulkarni AV, Langley M, Limbrick DD Jr, Luerssen TG, Oakes WJ, Riva-Cambrin J, Rozzelle C, Shannon C, Tamber M, Wellons JC 3rd, Whitehead WE, Kestle JRW, Hydrocephalus Clinical Research Network.
J Neurosurg Pediatr. 2018 Apr; 21(4)346-358. doi: 10.3171/2017.9.PEDS17112.

PMID:
    29393813
    [PubMed - in process]
Related citations


MRI-Guided Interstitial Laser Ablation for Intracranial Lesions: A Large Single-Institution Experience of 133 Cases.
Kamath AA, Friedman DD, Hacker CD, Smyth MD, Limbrick DD Jr, Kim AH, Hawasli AH, Leuthardt EC
Stereotact Funct Neurosurg. 2017; 95(6)417-428. doi: 10.1159/000485387.

PMID:
    29339639
    [PubMed - in process]
Related citations


An 8-Year-Old Girl with A Supratentorial Mass.
Schwetye KE, Gauvain K, Rodriguez D, Cottrell C, Limbrick DD Jr, Schmidt RE, Dahiya S
Brain Pathol. 2018 Jan; 28(1)125-126. doi: 10.1111/bpa.12576.

PMID:
    29265627
    [PubMed - indexed for MEDLINE]
Related citations


Endoscopic third ventriculostomy and choroid plexus cauterization in infant hydrocephalus: a prospective study by the Hydrocephalus Clinical Research Network.
Kulkarni AV, Riva-Cambrin J, Rozzelle CJ, Naftel RP, Alvey JS, Reeder RW, Holubkov R, Browd SR, Cochrane DD, Limbrick DD Jr, Simon TD, Tamber M, Wellons JC 3rd, Whitehead WE, Kestle JRW
J Neurosurg Pediatr. 2018 Mar; 21(3)214-223. doi: 10.3171/2017.8.PEDS17217.

PMID:
    29243972
    [PubMed - in process]
Related citations


Chemokine and cytokine levels in the lumbar cerebrospinal fluid of preterm infants with post-hemorrhagic hydrocephalus.
Habiyaremye G, Morales DM, Morgan CD, McAllister JP, CreveCoeur TS, Han RH, Gabir M, Baksh B, Mercer D, Limbrick DD Jr
Fluids Barriers CNS. 2017 Dec 12; 14(1)35. doi: 10.1186/s12987-017-0083-0.

PMID:
    29228970
    [PubMed - indexed for MEDLINE]
Related citations


On the role of the corpus callosum in interhemispheric functional connectivity in humans.
Roland JL, Snyder AZ, Hacker CD, Mitra A, Shimony JS, Limbrick DD, Raichle ME, Smyth MD, Leuthardt EC
Proc Natl Acad Sci U S A. 2017 Dec 12; 114(50)13278-13283. doi: 10.1073/pnas.1707050114.

PMID:
    29183973
    [PubMed - indexed for MEDLINE]
Related citations


Resting-state functional magnetic resonance imaging for surgical planning in pediatric patients: a preliminary experience.
Roland JL, Griffin N, Hacker CD, Vellimana AK, Akbari SH, Shimony JS, Smyth MD, Leuthardt EC, Limbrick DD Jr
J Neurosurg Pediatr. 2017 Dec; 20(6)583-590. doi: 10.3171/2017.6.PEDS1711.

PMID:
    28960172
    [PubMed - indexed for MEDLINE]
Related citations

In the News

Areas of Research Interest

Cerebrospinal fluid physiology and neonatal hydrocephalus.