FollowMyHealth Patient Portal

Faculty Physicians

David D. Limbrick, MD, PhD

Assistant Professor, Neurological Surgery
Assistant Professor, Pediatrics

Specialty Areas

Pediatric Neurosurgery
Pediatric Epilepsy
Brain Tumors - Pediatric

Board Certifications

Neurological Surgery

Areas of Clinical Interest

Pediatric neurosurgery, epilepsy surgery, neuro-endoscopy, hydrocephalus, pediatric brain tumors, deep brain stimulation, radiosurgery, pediatric spine.

  • Maps & Directions
  • Education
  • Publication & Research
  • In the News

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Office Phone: (314) 454-4630
Fax: (314) 454-2818

Education

Education

Residency: Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri 2007
Medical Degree: Medical College of Virginia, Virginia Commonwealth University 2001
Ph.D.: Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University 2000
Fellowship: Pediatric Neurosurgery, St. Louis Children's Hospital, St. Louis, Missouri 2007
B.S.: Biology, College of William and Mary, Williamsburg, Virginia 1992
M.S.: Physiology, Medical College of Virginia, Virginia Commonwealth University 1995

Publication & Research

Publication & Research

Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Part 4: Cerebrospinal fluid shunt or endoscopic third ventriculostomy for the treatment of hydrocephalus in children.
Limbrick DD Jr, Baird LC, Klimo P Jr, Riva-Cambrin J, Flannery AM, Pediatric Hydrocephalus Systematic Review and Evidence-Based Guidelines Task Force
J Neurosurg Pediatr. 2014 Nov; 14 Suppl 130-4. doi: 10.3171/2014.7.PEDS14324.

PMID:
    25988780
    [PubMed - indexed for MEDLINE]
Related citations


Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Part 2: Management of posthemorrhagic hydrocephalus in premature infants.
Mazzola CA, Choudhri AF, Auguste KI, Limbrick DD Jr, Rogido M, Mitchell L, Flannery AM, Pediatric Hydrocephalus Systematic Review and Evidence-Based Guidelines Task Force
J Neurosurg Pediatr. 2014 Nov; 14 Suppl 18-23. doi: 10.3171/2014.7.PEDS14322.

PMID:
    25988778
    [PubMed - indexed for MEDLINE]
Related citations


Foreword: Pediatric hydrocephalus: systematic literature review and evidence-based guidelines.
Flannery AM, Mazzola CA, Klimo P Jr, Duhaime AC, Baird LC, Tamber MS, Limbrick DD Jr, Nikas DC, Kemp J, Post AF, Auguste KI, Choudhri AF, Mitchell LS, Buffa D
J Neurosurg Pediatr. 2014 Nov; 14 Suppl 11-2. doi: 10.3171/2014.8.PEDS14426.

PMID:
    25988776
    [PubMed - indexed for MEDLINE]
Related citations


The accuracy of linear indices of ventricular volume in pediatric hydrocephalus: technical note.
Ragan DK, Cerqua J, Nash T, McKinstry RC, Shimony JS, Jones BV, Mangano FT, Holland SK, Yuan W, Limbrick DD Jr
J Neurosurg Pediatr. 2015 Jun; 15(6)547-51. doi: 10.3171/2014.10.PEDS14209.

PMID:
    25745953
    [PubMed - indexed for MEDLINE]
Related citations


Outcome methods used in clinical studies of Chiari malformation Type I: a systematic review.
Greenberg JK, Milner E, Yarbrough CK, Lipsey K, Piccirillo JF, Smyth MD, Park TS, Limbrick DD Jr
J Neurosurg. 2015 Feb; 122(2)262-72. doi: 10.3171/2014.9.JNS14406.

PMID:
    25380104
    [PubMed - indexed for MEDLINE]
Related citations


Endoscopic third ventriculostomy and choroid plexus cauterization in infants with hydrocephalus: a retrospective Hydrocephalus Clinical Research Network study.
Kulkarni AV, Riva-Cambrin J, Browd SR, Drake JM, Holubkov R, Kestle JR, Limbrick DD, Rozzelle CJ, Simon TD, Tamber MS, Wellons JC 3rd, Whitehead WE, Hydrocephalus Clinical Research Network
J Neurosurg Pediatr. 2014 Sep; 14(3)224-9. doi: 10.3171/2014.6.PEDS13492.

PMID:
    24995823
    [PubMed - indexed for MEDLINE]
Related citations


Developing the Pediatric Refractory Epilepsy Questionnaire: a pilot study.
Purusothaman V, Ryther RC, Bertrand M, Harker LA, Jeffe DB, Wallendorf M, Smyth MD, Limbrick DD
Epilepsy Behav. 2014 Aug; 3726-31. doi: 10.1016/j.yebeh.2014.04.025.

PMID:
    24967697
    [PubMed - indexed for MEDLINE]
Related citations


Comparison of posterior fossa decompression with or without duraplasty in children with Type I Chiari malformation.
Lee A, Yarbrough CK, Greenberg JK, Barber J, Limbrick DD, Smyth MD
Childs Nerv Syst. 2014 Aug; 30(8)1419-24. doi: 10.1007/s00381-014-2424-5.

PMID:
    24777296
    [PubMed - indexed for MEDLINE]
Related citations


External validation of the Chicago Chiari Outcome Scale.
Yarbrough CK, Greenberg JK, Smyth MD, Leonard JR, Park TS, Limbrick DD Jr
J Neurosurg Pediatr. 2014 Jun; 13(6)679-84. doi: 10.3171/2014.3.PEDS13503.

PMID:
    24724715
    [PubMed - indexed for MEDLINE]
Related citations


Management of children with mild traumatic brain injury and intracranial hemorrhage.
Greenberg JK, Stoev IT, Park TS, Smyth MD, Leonard JR, Leonard JC, Pineda JA, Limbrick DD
J Trauma Acute Care Surg. 2014 Apr; 76(4)1089-95. doi: 10.1097/TA.0000000000000155.

PMID:
    24662876
    [PubMed - indexed for MEDLINE]
Related citations


Risk factors for first cerebrospinal fluid shunt infection: findings from a multi-center prospective cohort study.
Simon TD, Butler J, Whitlock KB, Browd SR, Holubkov R, Kestle JR, Kulkarni AV, Langley M, Limbrick DD Jr, Mayer-Hamblett N, Tamber M, Wellons JC 3rd, Whitehead WE, Riva-Cambrin J, Hydrocephalus Clinical Research Network
J Pediatr. 2014 Jun; 164(6)1462-8.e2. doi: 10.1016/j.jpeds.2014.02.013.

PMID:
    24661340
    [PubMed - indexed for MEDLINE]
Related citations


Greater extent of resection improves ganglioglioma recurrence-free survival in children: a volumetric analysis.
Haydon DH, Dahiya S, Smyth MD, Limbrick DD, Leonard JR
Neurosurgery. 2014 Jul; 75(1)37-42. doi: 10.1227/NEU.0000000000000349.

PMID:
    24625425
    [PubMed - indexed for MEDLINE]
Related citations


Relationship of syrinx size and tonsillar descent to spinal deformity in Chiari malformation Type I with associated syringomyelia.
Godzik J, Kelly MP, Radmanesh A, Kim D, Holekamp TF, Smyth MD, Lenke LG, Shimony JS, Park TS, Leonard J, Limbrick DD
J Neurosurg Pediatr. 2014 Apr; 13(4)368-74. doi: 10.3171/2014.1.PEDS13105.

PMID:
    24527859
    [PubMed - indexed for MEDLINE]
Related citations


Editorial: neurosurgical winners.
Dacey RG Jr, Zipfel GJ, Limbrick DD Jr
J Neurosurg. 2014 Mar; 120(3)725-6. doi: 10.3171/2013.8.JNS131488.

PMID:
    24359007
    [PubMed - indexed for MEDLINE]
Related citations


Outcomes after anterior or complete corpus callosotomy in children.
Kasasbeh AS, Smyth MD, Steger-May K, Jalilian L, Bertrand M, Limbrick DD
Neurosurgery. 2014 Jan; 74(1)17-28; discussion 28. doi: 10.1227/NEU.0000000000000197.

PMID:
    24089047
    [PubMed - indexed for MEDLINE]
Related citations


White matter microstructural abnormality in children with hydrocephalus detected by probabilistic diffusion tractography.
Rajagopal A, Shimony JS, McKinstry RC, Altaye M, Maloney T, Mangano FT, Limbrick DD, Holland SK, Jones BV, Simpson S, Mercer D, Yuan W
AJNR Am J Neuroradiol. 2013 Dec; 34(12)2379-85. doi: 10.3174/ajnr.A3737.

PMID:
    24072621
    [PubMed - indexed for MEDLINE]
Related citations


Outcomes of CSF shunting in children: comparison of Hydrocephalus Clinical Research Network cohort with historical controls: clinical article.
Kulkarni AV, Riva-Cambrin J, Butler J, Browd SR, Drake JM, Holubkov R, Kestle JR, Limbrick DD, Simon TD, Tamber MS, Wellons JC 3rd, Whitehead WE, Hydrocephalus Clinical Research Network
J Neurosurg Pediatr. 2013 Oct; 12(4)334-8. doi: 10.3171/2013.7.PEDS12637.

PMID:
    23909616
    [PubMed - indexed for MEDLINE]
Related citations


Biopsy of the superficial cortex: predictors of effectiveness and outcomes.
Hawasli AH, Buckley RT, Gao F, Limbrick DD, Smyth MD, Leonard JR, Santiago P, Stewart TJ, Park TS, Grubb RL, Dowling JL, Leuthardt EC, Rich KM, Zipfel GJ, Dacey RG, Chicoine MR
Neurosurgery. 2013 Aug; 73(2)224-31; discussion 231-2; quiz 232. doi: 10.1227/01.neu.0000430310.63702.3e.

PMID:
    23632761
    [PubMed - indexed for MEDLINE]
Related citations


Health-related quality of life before and after pediatric epilepsy surgery: the influence of seizure outcome on changes in physical functioning and social functioning.
Titus JB, Lee A, Kasasbeh A, Thio LL, Stephenson J, Steger-May K, Limbrick DD Jr, Smyth MD
Epilepsy Behav. 2013 Jun; 27(3)477-83. doi: 10.1016/j.yebeh.2013.03.003.

PMID:
    23631952
    [PubMed - indexed for MEDLINE]
Related citations


Authors' reply.
Pineda JA, Leonard JR, Mazotas IG, Noetzel M, Limbrick DD, Keller MS, Gill J, Doctor A
Lancet Neurol. 2013 May; 12(5)427-8. doi: 10.1016/S1474-4422(13)70074-7.

PMID:
    23602159
    [PubMed - indexed for MEDLINE]
Related citations

In the News

Areas of Research Interest

Cerebrospinal fluid physiology and neonatal hydrocephalus.