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David B. Wilson, MD, PhD

Professor, Pediatrics
Division of Pediatric Hematology and Oncology
Professor, Molecular Biology and Pharmacology

Specialty Areas

Pediatric Hematology
Pediatric Kidney Transplant
Anticoagulation
Pediatric Oncology

Board Certifications

Pediatrics
Pediatric Hematology
Pediatric Oncology

Hospital Affiliations

St. Louis Children's Hospital

Areas of Clinical Interest

Coagulation disorders; Bone marrow failure

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: 9th Floor
Office Phone: 314-454-6018
Fax: 314-454-2780

St. Louis Children's Specialty Care Center

13001 North Outer Forty
St. Louis, MO 63017

Suite: E
Floor: 2
Office Phone: 314-454-6018
Fax: 314-454-2780

Education

Education

Fellowship: Pediatrics, Harvard Medical School, Boston, Massachusetts 1990
Fellowship: Medicine Hematology / Oncology, The Children's Hospital, Boston, Massachusetts 1990
Fellowship: Pediatrics, Hematology / Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 1989
Ph.D: Washington University School of Medicine, St. Louis, Missouri 1986
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 1986
B.A.: Kalamazoo College, Kalamazoo, Michigan 1980

Publication & Research

Publication & Research

Active spanning trees and Schramm-Loewner evolution.
Kassel A, Wilson DB
Phys Rev E. 2016 Jun; 93(6)062121. doi: 10.1103/PhysRevE.93.062121.

PMID:
    27415222
    [PubMed - in process]
Related citations


GATA4 Regulates Blood-Testis Barrier Function and Lactate Metabolism in Mouse Sertoli Cells.
Schrade A, Kyrönlahti A, Akinrinade O, Pihlajoki M, Fischer S, Rodriguez VM, Otte K, Velagapudi V, Toppari J, Wilson DB, Heikinheimo M
Endocrinology. 2016 Jun; 157(6)2416-31. doi: 10.1210/en.2015-1927.

PMID:
    26974005
    [PubMed - in process]
Related citations


Animal models of adrenocortical tumorigenesis.
Galac S, Wilson DB
Endocrinol Metab Clin North Am. 2015 Jun; 44(2)297-310. doi: 10.1016/j.ecl.2015.02.003.

PMID:
    26038202
    [PubMed - indexed for MEDLINE]
Related citations


GATA factors in endocrine neoplasia.
Pihlajoki M, Färkkilä A, Soini T, Heikinheimo M, Wilson DB
Mol Cell Endocrinol. 2016 Feb 5; 4212-17. doi: 10.1016/j.mce.2015.05.027.

PMID:
    26027919
    [PubMed - in process]
Related citations


Testicular steroidogenic cells to the rescue.
Heikinheimo M, Pihlajoki M, Schrade A, Kyrönlahti A, Wilson DB
Endocrinology. 2015 May; 156(5)1616-9. doi: 10.1210/en.2015-1222.

PMID:
    25886071
    [PubMed - indexed for MEDLINE]
Related citations


The maternal-age-associated risk of congenital heart disease is modifiable.
Schulkey CE, Regmi SD, Magnan RA, Danzo MT, Luther H, Hutchinson AK, Panzer AA, Grady MM, Wilson DB, Jay PY
Nature. 2015 Apr 9; 520(7546)230-3. doi: 10.1038/nature14361.

PMID:
    25830876
    [PubMed - indexed for MEDLINE]
Related citations


Adrenocortical zonation, renewal, and remodeling.
Pihlajoki M, Dörner J, Cochran RS, Heikinheimo M, Wilson DB
Front Endocrinol (Lausanne). 2015; 627. doi: 10.3389/fendo.2015.00027.

PMID:
    25798129
    [PubMed]
Related citations


The development and utility of a novel scale that quantifies the glycemic progression toward type 1 diabetes over 6 months.
Sosenko JM, Skyler JS, Beam CA, Boulware D, Mahon JL, Krischer JP, Greenbaum CJ, Rafkin LE, Matheson D, Herold KC, Palmer JP, Type 1 Diabetes TrialNet and Diabetes Prevention Trial–Type 1 Study Groups
Diabetes Care. 2015 May; 38(5)940-2. doi: 10.2337/dc14-2787.

PMID:
    25758770
    [PubMed - indexed for MEDLINE]
Related citations


GATA4 is a key regulator of steroidogenesis and glycolysis in mouse Leydig cells.
Schrade A, Kyrönlahti A, Akinrinade O, Pihlajoki M, Häkkinen M, Fischer S, Alastalo TP, Velagapudi V, Toppari J, Wilson DB, Heikinheimo M
Endocrinology. 2015 May; 156(5)1860-72. doi: 10.1210/en.2014-1931.

PMID:
    25668067
    [PubMed - indexed for MEDLINE]
Related citations


Toying with fate: Redirecting the differentiation of adrenocortical progenitor cells into gonadal-like tissue.
Röhrig T, Pihlajoki M, Ziegler R, Cochran RS, Schrade A, Schillebeeckx M, Mitra RD, Heikinheimo M, Wilson DB
Mol Cell Endocrinol. 2015 Jun 15; 408165-77. doi: 10.1016/j.mce.2014.12.003.

PMID:
    25498963
    [PubMed - indexed for MEDLINE]
Related citations


Novel markers of gonadectomy-induced adrenocortical neoplasia in the mouse and ferret.
Schillebeeckx M, Pihlajoki M, Gretzinger E, Yang W, Thol F, Hiller T, Löbs AK, Röhrig T, Schrade A, Cochran R, Jay PY, Heikinheimo M, Mitra RD, Wilson DB
Mol Cell Endocrinol. 2015 Jan 5; 399122-30. doi: 10.1016/j.mce.2014.09.029.

PMID:
    25289806
    [PubMed - indexed for MEDLINE]
Related citations


Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival.
Gautier EL, Ivanov S, Williams JW, Huang SC, Marcelin G, Fairfax K, Wang PL, Francis JS, Leone P, Wilson DB, Artyomov MN, Pearce EJ, Randolph GJ
J Exp Med. 2014 Jul 28; 211(8)1525-31. doi: 10.1084/jem.20140570.

PMID:
    25024137
    [PubMed - indexed for MEDLINE]
Related citations


Validation is a dish oft served cold.
Wilson DB
Blood. 2014 Jun 12; 123(24)3688-9. doi: 10.1182/blood-2014-05-572925.

PMID:
    24926068
    [PubMed - indexed for MEDLINE]
Related citations


Inherited bone marrow failure syndromes in adolescents and young adults.
Wilson DB, Link DC, Mason PJ, Bessler M
Ann Med. 2014 Sep; 46(6)353-63. doi: 10.3109/07853890.2014.915579.

PMID:
    24888387
    [PubMed - indexed for MEDLINE]
Related citations


Never underestimate the complexity of remodeling.
Pihlajoki M, Heikinheimo M, Wilson DB
Endocrinology. 2013 Dec; 154(12)4446-9. doi: 10.1210/en.2013-1982.

PMID:
    24273232
    [PubMed - indexed for MEDLINE]
Related citations


Laser capture microdissection-reduced representation bisulfite sequencing (LCM-RRBS) maps changes in DNA methylation associated with gonadectomy-induced adrenocortical neoplasia in the mouse.
Schillebeeckx M, Schrade A, Löbs AK, Pihlajoki M, Wilson DB, Mitra RD
Nucleic Acids Res. 2013 Jun; 41(11)e116. doi: 10.1093/nar/gkt230.

PMID:
    23589626
    [PubMed - indexed for MEDLINE]
Related citations


Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice.
Pihlajoki M, Gretzinger E, Cochran R, Kyrönlahti A, Schrade A, Hiller T, Sullivan L, Shoykhet M, Schoeller EL, Brooks MD, Heikinheimo M, Wilson DB
Endocrinology. 2013 May; 154(5)1754-67. doi: 10.1210/en.2012-1892.

PMID:
    23471215
    [PubMed - indexed for MEDLINE]
Related citations


GATA4 is a critical regulator of gonadectomy-induced adrenocortical tumorigenesis in mice.
Krachulec J, Vetter M, Schrade A, Löbs AK, Bielinska M, Cochran R, Kyrönlahti A, Pihlajoki M, Parviainen H, Jay PY, Heikinheimo M, Wilson DB
Endocrinology. 2012 Jun; 153(6)2599-611. doi: 10.1210/en.2011-2135.

PMID:
    22461617
    [PubMed - indexed for MEDLINE]
Related citations


The role of myotubularin-related phosphatases in the control of autophagy and programmed cell death.
Zou J, Majerus PW, Wilson DB, Schrade A, Chang SC, Wilson MP
Adv Biol Regul. 2012 Jan; 52(1)282-9.

PMID:
    22056831
    [PubMed - indexed for MEDLINE]
Related citations


GATA4 deficiency impairs ovarian function in adult mice.
Kyrönlahti A, Vetter M, Euler R, Bielinska M, Jay PY, Anttonen M, Heikinheimo M, Wilson DB
Biol Reprod. 2011 May; 84(5)1033-44. doi: 10.1095/biolreprod.110.086850.

PMID:
    21248289
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Role of transcription factors in the regulation of differentiation, development and oncogenesis