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David B. Wilson, MD, PhD

Professor, Pediatrics
Division of Pediatric Hematology and Oncology
Professor, Molecular Biology and Pharmacology

Specialty Areas

Pediatric Hematology
Pediatric Kidney Transplant
Anticoagulation
Pediatric Oncology

Board Certifications

Pediatrics
Pediatric Hematology
Pediatric Oncology

Hospital Affiliations

St. Louis Children's Hospital

Areas of Clinical Interest

Coagulation disorders; Bone marrow failure

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: 9th Floor
Office Phone: 314-454-6018
Fax: 314-454-2780

St. Louis Children's Specialty Care Center

13001 North Outer Forty
St. Louis, MO 63017

Suite: E
Floor: 2
Office Phone: 314-454-6018
Fax: 314-454-2780

Education

Education

Fellowship: Pediatrics, Harvard Medical School, Boston, Massachusetts 1990
Fellowship: Medicine Hematology / Oncology, The Children's Hospital, Boston, Massachusetts 1990
Fellowship: Pediatrics, Hematology / Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 1989
Ph.D: Washington University School of Medicine, St. Louis, Missouri 1986
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 1986
B.A.: Kalamazoo College, Kalamazoo, Michigan 1980

Publication & Research

Publication & Research

Probing GATA factor function in mouse Leydig cells via testicular injection of adenoviral vectors.
Penny GM, Cochran RB, Pihlajoki M, Kyrönlahti A, Schrade A, Häkkinen M, Toppari J, Heikinheimo M, Wilson DB
Reproduction. 2017 Jul 14; pii: REP-17-0311. doi: 10.1530/REP-17-0311.

PMID:
    28710293
    [PubMed - as supplied by publisher]
Related citations


Six-vertex model and Schramm-Loewner evolution.
Kenyon R, Miller J, Sheffield S, Wilson DB
Phys Rev E. 2017 May; 95(5-1)052146. doi: 10.1103/PhysRevE.95.052146.

PMID:
    28618540
    [PubMed - in process]
Related citations


Nkx2-5 and Sarcospan genetically interact in the development of the muscular ventricular septum of the heart.
Panzer AA, Regmi SD, Cormier D, Danzo MT, Chen ID, Winston JB, Hutchinson AK, Salm D, Schulkey CE, Cochran RS, Wilson DB, Jay PY
Sci Rep. 2017 Apr 13; 746438. doi: 10.1038/srep46438.

PMID:
    28406175
    [PubMed - in process]
Related citations


Downregulation of transcription factor GATA4 sensitizes human hepatoblastoma cells to doxorubicin-induced apoptosis.
Soini T, Pihlajoki M, Kyrönlahti A, Andersson LC, Wilson DB, Heikinheimo M
Tumour Biol. 2017 Mar; 39(3)1010428317695016. doi: 10.1177/1010428317695016.

PMID:
    28349834
    [PubMed - indexed for MEDLINE]
Related citations


Special issue: Impact of maternal metabolism on newborn heath.
Wilson DB
Mol Cell Endocrinol. 2016 Nov 5; 4351. doi: 10.1016/j.mce.2016.08.038.

PMID:
    27597542
    [PubMed - in process]
Related citations


GLI1<sup>+</sup> progenitor cells in the adrenal capsule of the adult mouse give rise to heterotopic gonadal-like tissue.
Dörner J, Martinez Rodriguez V, Ziegler R, Röhrig T, Cochran RS, Götz RM, Levin MD, Pihlajoki M, Heikinheimo M, Wilson DB
Mol Cell Endocrinol. 2017 Feb 5; 441164-175. doi: 10.1016/j.mce.2016.08.043.

PMID:
    27585489
    [PubMed - in process]
Related citations


Active spanning trees and Schramm-Loewner evolution.
Kassel A, Wilson DB
Phys Rev E. 2016 Jun; 93(6)062121. doi: 10.1103/PhysRevE.93.062121.

PMID:
    27415222
    [PubMed - in process]
Related citations


GATA4 Regulates Blood-Testis Barrier Function and Lactate Metabolism in Mouse Sertoli Cells.
Schrade A, Kyrönlahti A, Akinrinade O, Pihlajoki M, Fischer S, Rodriguez VM, Otte K, Velagapudi V, Toppari J, Wilson DB, Heikinheimo M
Endocrinology. 2016 Jun; 157(6)2416-31. doi: 10.1210/en.2015-1927.

PMID:
    26974005
    [PubMed - indexed for MEDLINE]
Related citations


Animal models of adrenocortical tumorigenesis.
Galac S, Wilson DB
Endocrinol Metab Clin North Am. 2015 Jun; 44(2)297-310. doi: 10.1016/j.ecl.2015.02.003.

PMID:
    26038202
    [PubMed - indexed for MEDLINE]
Related citations


GATA factors in endocrine neoplasia.
Pihlajoki M, Färkkilä A, Soini T, Heikinheimo M, Wilson DB
Mol Cell Endocrinol. 2016 Feb 5; 4212-17. doi: 10.1016/j.mce.2015.05.027.

PMID:
    26027919
    [PubMed - indexed for MEDLINE]
Related citations


Testicular steroidogenic cells to the rescue.
Heikinheimo M, Pihlajoki M, Schrade A, Kyrönlahti A, Wilson DB
Endocrinology. 2015 May; 156(5)1616-9. doi: 10.1210/en.2015-1222.

PMID:
    25886071
    [PubMed - indexed for MEDLINE]
Related citations


The maternal-age-associated risk of congenital heart disease is modifiable.
Schulkey CE, Regmi SD, Magnan RA, Danzo MT, Luther H, Hutchinson AK, Panzer AA, Grady MM, Wilson DB, Jay PY
Nature. 2015 Apr 9; 520(7546)230-3. doi: 10.1038/nature14361.

PMID:
    25830876
    [PubMed - indexed for MEDLINE]
Related citations


Adrenocortical zonation, renewal, and remodeling.
Pihlajoki M, Dörner J, Cochran RS, Heikinheimo M, Wilson DB
Front Endocrinol (Lausanne). 2015; 627. doi: 10.3389/fendo.2015.00027.

PMID:
    25798129
    [PubMed]
Related citations


The development and utility of a novel scale that quantifies the glycemic progression toward type 1 diabetes over 6 months.
Sosenko JM, Skyler JS, Beam CA, Boulware D, Mahon JL, Krischer JP, Greenbaum CJ, Rafkin LE, Matheson D, Herold KC, Palmer JP, Type 1 Diabetes TrialNet and Diabetes Prevention Trial–Type 1 Study Groups.
Diabetes Care. 2015 May; 38(5)940-2. doi: 10.2337/dc14-2787.

PMID:
    25758770
    [PubMed - indexed for MEDLINE]
Related citations


GATA4 is a key regulator of steroidogenesis and glycolysis in mouse Leydig cells.
Schrade A, Kyrönlahti A, Akinrinade O, Pihlajoki M, Häkkinen M, Fischer S, Alastalo TP, Velagapudi V, Toppari J, Wilson DB, Heikinheimo M
Endocrinology. 2015 May; 156(5)1860-72. doi: 10.1210/en.2014-1931.

PMID:
    25668067
    [PubMed - indexed for MEDLINE]
Related citations


Toying with fate: Redirecting the differentiation of adrenocortical progenitor cells into gonadal-like tissue.
Röhrig T, Pihlajoki M, Ziegler R, Cochran RS, Schrade A, Schillebeeckx M, Mitra RD, Heikinheimo M, Wilson DB
Mol Cell Endocrinol. 2015 Jun 15; 408165-77. doi: 10.1016/j.mce.2014.12.003.

PMID:
    25498963
    [PubMed - indexed for MEDLINE]
Related citations


Novel markers of gonadectomy-induced adrenocortical neoplasia in the mouse and ferret.
Schillebeeckx M, Pihlajoki M, Gretzinger E, Yang W, Thol F, Hiller T, Löbs AK, Röhrig T, Schrade A, Cochran R, Jay PY, Heikinheimo M, Mitra RD, Wilson DB
Mol Cell Endocrinol. 2015 Jan 5; 399122-30. doi: 10.1016/j.mce.2014.09.029.

PMID:
    25289806
    [PubMed - indexed for MEDLINE]
Related citations


Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival.
Gautier EL, Ivanov S, Williams JW, Huang SC, Marcelin G, Fairfax K, Wang PL, Francis JS, Leone P, Wilson DB, Artyomov MN, Pearce EJ, Randolph GJ
J Exp Med. 2014 Jul 28; 211(8)1525-31. doi: 10.1084/jem.20140570.

PMID:
    25024137
    [PubMed - indexed for MEDLINE]
Related citations


Validation is a dish oft served cold.
Wilson DB
Blood. 2014 Jun 12; 123(24)3688-9. doi: 10.1182/blood-2014-05-572925.

PMID:
    24926068
    [PubMed - indexed for MEDLINE]
Related citations


Inherited bone marrow failure syndromes in adolescents and young adults.
Wilson DB, Link DC, Mason PJ, Bessler M
Ann Med. 2014 Sep; 46(6)353-63. doi: 10.3109/07853890.2014.915579.

PMID:
    24888387
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Role of transcription factors in the regulation of differentiation, development and oncogenesis