Patient Portal

David A. Rosen, MD, PhD

Instructor, Pediatrics
Division of Pediatric Infectious Diseases

Specialty Areas

Pediatric Infectious Disease
Infectious Diseases

Board Certifications


Hospital Affiliations

St. Louis Children's Hospital

Referral Information

Physician Referral Required

Areas of Clinical Interest

Pediatric infectious diseases, resistant bacterial infections

  • Location(s)
  • Education
  • Publication & Research



St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: D
Floor: 2
Office Phone: 314-454-6050
Fax: 314-454-2836



Fellowship, Pediatric Infectious Diseases: Washington University School of Medicine, St. Louis, Missouri, 2016
Residency, Pediatrics: Washington University School of Medicine, St. Louis, Missouri, 2012
Medical Degree: Washington University School of Medicine, St. Louis, Missouri, 2010
PhD, Molecular Microbiology: Washington University School of Medicine, St. Louis, Missouri, 2010

Publication & Research

Publication & Research

1. Rosen DA, Hooton TM, Stamm WE, Humphrey PA, Hultgren SJ. Detection of intracellular bacterial communities in human urinary tract infection. PLoS Med. 2007;4(12):e329.PMCID:PMC2140087 PMID:18092884

2. Rosen DA, Pinkner JS, Walker JN, Elam JS, Jones JM, Hultgren SJ. Molecular variations in Klebsiella pneumoniae and Escherichia coli FimH affect function and pathogenesis in the urinary tract. Infect Immun. 2008;76(7):3346-

56.PMCID:PMC2446687 PMID:18474655

3. Rosen DA, Pinkner JS, Jones JM, Walker JN, Clegg S, Hultgren SJ. Utilization of an intracellular bacterial community pathway in Klebsiella pneumoniae urinary tract infection and the effects of FimK on type 1 pilus expression. Infect Immun.

2008;76(7):3337-45.PMCID:PMC2446714 PMID:18411285

4. Rosen DA, Hung CS, Kline KA, Hultgren SJ. Streptozocin-induced diabetic mouse model of urinary tract infection. Infect Immun. 2008;76(9):4290-8.PMCID:PMC2519435 PMID:18644886

5. Rosen DA, Hilliard JK, Tiemann KM, Todd EM, Morley SC, Hunstad DA. 

Klebsiella pneumoniae FimK Promotes Virulence in Murine Pneumonia. J Infect Dis. 2016;213(4):649-58.PMCID:PMC4721909 PMID:26347570

Areas of Research Interest

Pathogenesis of Klebsiella pneumoniae infections. Klebsiella is often resistant to a variety of antimicrobials making it difficult to eradicate.  Our primary goal is to discover novel therapeutic targets for interventions that will prevent and treat Klebsiella infections of the lung, bloodstream and urinary tract.