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Faculty Physicians

David A. Hunstad, MD

Associate Professor, Pediatrics
Chief, Division of Infectious Diseases
Associate Professor, Molecular Microbiology

Specialty Areas

Infectious Diseases
Pediatric Diagnostics
Pediatric Infectious Disease

Board Certifications

Pediatric Infectious Diseases
Pediatrics

Areas of Clinical Interest

Pediatric infectious diseases, urinary tract infections, diagnostic medicine  

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Office Phone: 314-454-6050
Fax: 314-454-2836

Education

Education

Residency, Pediatrics: St. Louis Children's Hospital, St. Louis, MO 1998
Chief Resident, Pediatrics: St. Louis Children's Hospital, St Louis, MO 1999
Fellowship: Pediatric Infectious Diseases, Washington University School of Medicine, St. Louis MO 63110 2003
B.A.: Carleton College, Northfield, Minnesota 1991
Medical Degree: Washington University School of Medicine, St. Louis, MO 1995

Publication & Research

Publication & Research

Cathelicidin augments epithelial receptivity and pathogenesis in experimental Escherichia coli cystitis.
Danka ES, Hunstad DA
J Infect Dis. 2015 Apr 1; 211(7)1164-73. doi: 10.1093/infdis/jiu577.

PMID:
    25336727
    [PubMed - indexed for MEDLINE]
Related citations


Bacterial lysis liberates the neutrophil migration suppressor YbcL from the periplasm of uropathogenic Escherichia coli.
Lau ME, Danka ES, Tiemann KM, Hunstad DA
Infect Immun. 2014 Dec; 82(12)4921-30. doi: 10.1128/IAI.01838-14.

PMID:
    25183735
    [PubMed - indexed for MEDLINE]
Related citations


Scurvy revealed by difficulty walking: three cases in young children.
Kitcharoensakkul M, Schulz CG, Kassel R, Khanna G, Liang S, Ngwube A, Baszis KW, Hunstad DA, White AJ
J Clin Rheumatol. 2014 Jun; 20(4)224-8. doi: 10.1097/RHU.0000000000000101.

PMID:
    24847751
    [PubMed - indexed for MEDLINE]
Related citations


Quantitative assessment of human neutrophil migration across a cultured bladder epithelium.
Lau ME, Hunstad DA
J Vis Exp. 2013 Nov 7; (81)e50919. doi: 10.3791/50919.

PMID:
    24300797
    [PubMed - indexed for MEDLINE]
Related citations


Vancomycin trough concentrations in overweight or obese pediatric patients.
Heble DE Jr, McPherson C, Nelson MP, Hunstad DA
Pharmacotherapy. 2013 Dec; 33(12)1273-7. doi: 10.1002/phar.1321.

PMID:
    23798327
    [PubMed - indexed for MEDLINE]
Related citations


A serologic correlate of protective immunity against community-onset Staphylococcus aureus infection.
Fritz SA, Tiemann KM, Hogan PG, Epplin EK, Rodriguez M, Al-Zubeidi DN, Bubeck Wardenburg J, Hunstad DA
Clin Infect Dis. 2013 Jun; 56(11)1554-61. doi: 10.1093/cid/cit123.

PMID:
    23446627
    [PubMed - indexed for MEDLINE]
Related citations


YbcL of uropathogenic Escherichia coli suppresses transepithelial neutrophil migration.
Lau ME, Loughman JA, Hunstad DA
Infect Immun. 2012 Dec; 80(12)4123-32. doi: 10.1128/IAI.00801-12.

PMID:
    22966043
    [PubMed - indexed for MEDLINE]
Related citations


Oseltamivir dosing in premature infants.
McPherson C, Warner B, Hunstad DA, Elward A, Acosta EP
J Infect Dis. 2012 Sep 15; 206(6)847-50. doi: 10.1093/infdis/jis471.

PMID:
    22807525
    [PubMed - indexed for MEDLINE]
Related citations


Induction of indoleamine 2,3-dioxygenase by uropathogenic bacteria attenuates innate responses to epithelial infection.
Loughman JA, Hunstad DA
J Infect Dis. 2012 Jun 15; 205(12)1830-9. doi: 10.1093/infdis/jis280.

PMID:
    22474038
    [PubMed - indexed for MEDLINE]
Related citations


UPEC hemolysin: more than just for making holes.
Justice SS, Hunstad DA
Cell Host Microbe. 2012 Jan 19; 11(1)4-5. doi: 10.1016/j.chom.2012.01.001.

PMID:
    22264508
    [PubMed - indexed for MEDLINE]
Related citations


The natural history of contemporary Staphylococcus aureus nasal colonization in community children.
Fritz SA, Krauss MJ, Epplin EK, Burnham CA, Garbutt J, Dunne WM, Hunstad DA, Storch GA
Pediatr Infect Dis J. 2011 Apr; 30(4)349-51. doi: 10.1097/INF.0b013e3181fe075e.

PMID:
    21412205
    [PubMed - indexed for MEDLINE]
Related citations


Attenuation of human neutrophil migration and function by uropathogenic bacteria.
Loughman JA, Hunstad DA
Microbes Infect. 2011 Jun; 13(6)555-65. doi: 10.1016/j.micinf.2011.01.017.

PMID:
    21315174
    [PubMed - indexed for MEDLINE]
Related citations


Morphological plasticity promotes resistance to phagocyte killing of uropathogenic Escherichia coli.
Horvath DJ Jr, Li B, Casper T, Partida-Sanchez S, Hunstad DA, Hultgren SJ, Justice SS
Microbes Infect. 2011 May; 13(5)426-37. doi: 10.1016/j.micinf.2010.12.004.

PMID:
    21182979
    [PubMed - indexed for MEDLINE]
Related citations


Intracellular lifestyles and immune evasion strategies of uropathogenic Escherichia coli.
Hunstad DA, Justice SS
Annu Rev Microbiol. 2010; 64203-21. doi: 10.1146/annurev.micro.112408.134258.

PMID:
    20825346
    [PubMed - indexed for MEDLINE]
Related citations


contribution of genetically restricted, methicillin-susceptible strains to the ongoing epidemic of community-acquired Staphylococcus aureus infections.
Orscheln RC, Hunstad DA, Fritz SA, Loughman JA, Mitchell K, Storch EK, Gaudreault M, Sellenriek PL, Armstrong JR, Mardis ER, Storch GA
Clin Infect Dis. 2009 Aug 15; 49(4)536-42. doi: 10.1086/600881.

PMID:
    19589082
    [PubMed - indexed for MEDLINE]
Related citations


Virulence gene expression in human community-acquired Staphylococcus aureus infection.
Loughman JA, Fritz SA, Storch GA, Hunstad DA
J Infect Dis. 2009 Feb 1; 199(3)294-301. doi: 10.1086/595982.

PMID:
    19115951
    [PubMed - indexed for MEDLINE]
Related citations


Morphological plasticity as a bacterial survival strategy.
Justice SS, Hunstad DA, Cegelski L, Hultgren SJ
Nat Rev Microbiol. 2008 Feb; 6(2)162-8.

PMID:
    18157153
    [PubMed - indexed for MEDLINE]
Related citations


Salmonella ovarian abscess in an adolescent.
Miller AS, Hunstad DA
Pediatr Infect Dis J. 2007 Jun; 26(6)548-9.

PMID:
    17529879
    [PubMed - indexed for MEDLINE]
Related citations


Filamentation by Escherichia coli subverts innate defenses during urinary tract infection.
Justice SS, Hunstad DA, Seed PC, Hultgren SJ
Proc Natl Acad Sci U S A. 2006 Dec 26; 103(52)19884-9.

PMID:
    17172451
    [PubMed - indexed for MEDLINE]
Related citations


Histoplasmosis in a child with JRA on low-dose methotrexate.
Hunstad DA, French AR
Rheumatology (Oxford). 2007 Jan; 46(1)177-8.

PMID:
    17114804
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Work in our laboratory focuses on the interactions of pathogenic bacteria with their hosts.  We aim to elucidate the modulation of host immune responses by pathogens and to determine the mechanisms by which these bacteria present specific virulence factors on their surfaces.  Our primary goal is to discover novel targets for interventions that will prevent and treat bacterial infections of the urinary tract, gastrointestinal tract, and central nervous system.  


Hunstad Lab Web Page