Patient Portal

David A. Hunstad, MD

Associate Professor, Pediatrics
Chief, Division of Infectious Diseases
Associate Professor, Molecular Microbiology

Specialty Areas

Infectious Diseases
Pediatric Diagnostics
Pediatric Infectious Disease

Board Certifications

Pediatric Infectious Diseases
Pediatrics

Hospital Affiliations

St. Louis Children's Hospital

Areas of Clinical Interest

Pediatric infectious diseases, urinary tract infections, diagnostic medicine  

  • Maps & Directions
  • Education
  • Publication & Research
  • Financial Disclosures

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Office Phone: 314-454-6050
Fax: 314-454-2836

Education

Education

Residency, Pediatrics: St. Louis Children's Hospital, St. Louis, MO 1998
Chief Resident, Pediatrics: St. Louis Children's Hospital, St Louis, MO 1999
Fellowship: Pediatric Infectious Diseases, Washington University School of Medicine, St. Louis MO 63110 2003
B.A.: Carleton College, Northfield, Minnesota 1991
Medical Degree: Washington University School of Medicine, St. Louis, MO 1995

Publication & Research

Publication & Research

Carriage of the Toxic Shock Syndrome Toxin Gene by Contemporary Community-Associated Staphylococcus aureus Isolates.
Parrish KL, Wylie KM, Reich PJ, Hogan PG, Wylie TN, Kennedy CR, Lainhart W, Hunstad DA, Burnham CD, Fritz SA
J Pediatric Infect Dis Soc. 2018 Oct 4; doi: 10.1093/jpids/piy098.

PMID:
    30285124
    [PubMed - as supplied by publisher]
Related citations


Correction: Renal scar formation and kidney function following antibiotic-treated murine pyelonephritis (doi: 10.1242/dmm.030130).
Olson PD, McLellan LK, Liu A, Briden KE, Tiemann KM, Daugherty AL, Hruska KA, Hunstad DA
Dis Model Mech. 2018 Sep 13; 11(9)pii: dmm036798. doi: 10.1242/dmm.036798.

PMID:
    30213794
    [PubMed - in process]
Related citations


Androgen exposure potentiates formation of intratubular communities and renal abscesses by Escherichia coli.
Olson PD, McLellan LK, Hreha TN, Liu A, Briden KE, Hruska KA, Hunstad DA
Kidney Int. 2018 Sep; 94(3)502-513. doi: 10.1016/j.kint.2018.04.023.

PMID:
    30041870
    [PubMed - in process]
Related citations


A Vinyl Ether-Functional Polycarbonate as a Template for Multiple Postpolymerization Modifications.
Cho S, Heo GS, Khan S, Huang J, Hunstad DA, Elsabahy M, Wooley KL
Macromolecules. 2018 May 8; 51(9)3233-3242. doi: 10.1021/acs.macromol.8b00047.

PMID:
    29915431
    [PubMed]
Related citations


Mass spectrometric measurement of urinary kynurenine-to-tryptophan ratio in children with and without urinary tract infection.
Yarbrough ML, Briden KE, Mitsios JV, Weindel AL, Terrill CM, Hunstad DA, Dietzen DJ
Clin Biochem. 2018 Jun; 5683-88. doi: 10.1016/j.clinbiochem.2018.04.014.

PMID:
    29679555
    [PubMed - indexed for MEDLINE]
Related citations


Goblet cell associated antigen passages are inhibited during Salmonella typhimurium infection to prevent pathogen dissemination and limit responses to dietary antigens.
Kulkarni DH, McDonald KG, Knoop KA, Gustafsson JK, Kozlowski KM, Hunstad DA, Miller MJ, Newberry RD
Mucosal Immunol. 2018 Jul; 11(4)1103-1113. doi: 10.1038/s41385-018-0007-6.

PMID:
    29445136
    [PubMed - in process]
Related citations


High Levels of Cyclic Di-GMP in Klebsiella pneumoniae Attenuate Virulence in the Lung.
Rosen DA, Twentyman J, Hunstad DA
Infect Immun. 2018 Feb; 86(2)pii: e00647-17. doi: 10.1128/IAI.00647-17.

PMID:
    29158434
    [PubMed - indexed for MEDLINE]
Related citations


Renal scar formation and kidney function following antibiotic-treated murine pyelonephritis.
Olson PD, McLellan LK, Liu A, Briden KE, Tiemann KM, Daugherty AL, Hruska KA, Hunstad DA
Dis Model Mech. 2017 Nov 1; 10(11)1371-1379. doi: 10.1242/dmm.030130.

PMID:
    28882930
    [PubMed - indexed for MEDLINE]
Related citations


Synthesis, characterization, in vitro SAR and in vivo evaluation of N,N'bisnaphthylmethyl 2-alkyl substituted imidazolium salts against NSCLC.
DeBord MA, Southerland MR, Wagers PO, Tiemann KM, Robishaw NK, Whiddon KT, Konopka MC, Tessier CA, Shriver LP, Paruchuri S, Hunstad DA, Panzner MJ, Youngs WJ
Bioorg Med Chem Lett. 2017 Feb 15; 27(4)764-775. doi: 10.1016/j.bmcl.2017.01.035.

PMID:
    28126518
    [PubMed - indexed for MEDLINE]
Related citations


Urinary Tract Infection: Pathogenesis and Outlook.
McLellan LK, Hunstad DA
Trends Mol Med. 2016 Nov; 22(11)946-957. doi: 10.1016/j.molmed.2016.09.003.

PMID:
    27692880
    [PubMed - indexed for MEDLINE]
Related citations


Polymeric nanoparticles in development for treatment of pulmonary infectious diseases.
Lim YH, Tiemann KM, Hunstad DA, Elsabahy M, Wooley KL
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016 Nov; 8(6)842-871. doi: 10.1002/wnan.1401.

PMID:
    27016134
    [PubMed - indexed for MEDLINE]
Related citations


Local Generation of Kynurenines Mediates Inhibition of Neutrophil Chemotaxis by Uropathogenic Escherichia coli.
Loughman JA, Yarbrough ML, Tiemann KM, Hunstad DA
Infect Immun. 2016 Apr; 84(4)1176-1183. doi: 10.1128/IAI.01202-15.

PMID:
    26857571
    [PubMed - indexed for MEDLINE]
Related citations


Subversion of Host Innate Immunity by Uropathogenic Escherichia coli.
Olson PD, Hunstad DA
Pathogens. 2016 Jan 4; 5(1)pii: E2. doi: 10.3390/pathogens5010002.

PMID:
    26742078
    [PubMed]
Related citations


A Murine Model for Escherichia coli Urinary Tract Infection.
Hannan TJ, Hunstad DA
Methods Mol Biol. 2016; 1333159-75. doi: 10.1007/978-1-4939-2854-5_14.

PMID:
    26468108
    [PubMed - indexed for MEDLINE]
Related citations


Androgens Enhance Male Urinary Tract Infection Severity in a New Model.
Olson PD, Hruska KA, Hunstad DA
J Am Soc Nephrol. 2016 Jun; 27(6)1625-34. doi: 10.1681/ASN.2015030327.

PMID:
    26449605
    [PubMed - indexed for MEDLINE]
Related citations


Klebsiella pneumoniae FimK Promotes Virulence in Murine Pneumonia.
Rosen DA, Hilliard JK, Tiemann KM, Todd EM, Morley SC, Hunstad DA
J Infect Dis. 2016 Feb 15; 213(4)649-58. doi: 10.1093/infdis/jiv440.

PMID:
    26347570
    [PubMed - indexed for MEDLINE]
Related citations


Imidazolium salts as small-molecule urinary bladder exfoliants in a murine model.
Wagers PO, Tiemann KM, Shelton KL, Kofron WG, Panzner MJ, Wooley KL, Youngs WJ, Hunstad DA
Antimicrob Agents Chemother. 2015 Sep; 59(9)5494-502. doi: 10.1128/AAC.00881-15.

PMID:
    26124168
    [PubMed - indexed for MEDLINE]
Related citations


Vitamin D sufficiency and Staphylococcus aureus infection in children.
Wang JW, Hogan PG, Hunstad DA, Fritz SA
Pediatr Infect Dis J. 2015 May; 34(5)544-5. doi: 10.1097/INF.0000000000000667.

PMID:
    25860535
    [PubMed - indexed for MEDLINE]
Related citations


Molecular Epidemiology of Recurrent Cutaneous Methicillin-Resistant Staphylococcus aureus Infections in Children.
Al-Zubeidi D, Burnham CA, Hogan PG, Collins R, Hunstad DA, Fritz SA
J Pediatric Infect Dis Soc. 2014 Sep; 3(3)261-4. doi: 10.1093/jpids/pit046.

PMID:
    25844165
    [PubMed]
Related citations


Preparation and in vitro antimicrobial activity of silver-bearing degradable polymeric nanoparticles of polyphosphoester-block-poly(L-lactide).
Lim YH, Tiemann KM, Heo GS, Wagers PO, Rezenom YH, Zhang S, Zhang F, Youngs WJ, Hunstad DA, Wooley KL
ACS Nano. 2015 Feb 24; 9(2)1995-2008. doi: 10.1021/nn507046h.

PMID:
    25621868
    [PubMed - indexed for MEDLINE]
Related citations

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians and health professionals are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians and health professionals work collaboratively with pharmaceutical, medical device or other medical care related companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our physicians and health professionals have an ownership or potential ownership interest in a commercial company; and/or are paid by a commercial company to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians or health professionals must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this website, physicians and health professionals earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following financial interests during calendar year 2017:

Company Name: Bioversys

Royalties:

Equity: Yes

Consulting/Advisory Board:

Speaker Fees:

Reporting Date: May 01, 2018

Areas of Research Interest

Work in our laboratory focuses on the interactions of pathogenic bacteria with their hosts.  We aim to elucidate the modulation of host immune responses by pathogens and to determine the mechanisms by which these bacteria present specific virulence factors on their surfaces.  Our primary goal is to discover novel targets for interventions that will prevent and treat bacterial infections of the urinary tract, gastrointestinal tract, and central nervous system.  


Hunstad Lab Web Page