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David A. Hunstad, MD

Associate Professor, Pediatrics
Chief, Division of Infectious Diseases
Associate Professor, Molecular Microbiology

Specialty Areas

Infectious Diseases
Pediatric Diagnostics
Pediatric Infectious Disease

Board Certifications

Pediatric Infectious Diseases
Pediatrics

Hospital Affiliations

St. Louis Children's Hospital

Areas of Clinical Interest

Pediatric infectious diseases, urinary tract infections, diagnostic medicine  

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Office Phone: 314-454-6050
Fax: 314-454-2836

Education

Education

Residency, Pediatrics: St. Louis Children's Hospital, St. Louis, MO 1998
Chief Resident, Pediatrics: St. Louis Children's Hospital, St Louis, MO 1999
Fellowship: Pediatric Infectious Diseases, Washington University School of Medicine, St. Louis MO 63110 2003
B.A.: Carleton College, Northfield, Minnesota 1991
Medical Degree: Washington University School of Medicine, St. Louis, MO 1995

Publication & Research

Publication & Research

Polymeric nanoparticles in development for treatment of pulmonary infectious diseases.
Lim YH, Tiemann KM, Hunstad DA, Elsabahy M, Wooley KL
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016 Mar 25; doi: 10.1002/wnan.1401.

PMID:
    27016134
    [PubMed - as supplied by publisher]
Related citations


Local Generation of Kynurenines Mediates Inhibition of Neutrophil Chemotaxis by Uropathogenic Escherichia coli.
Loughman JA, Yarbrough ML, Tiemann KM, Hunstad DA
Infect Immun. 2016 Apr; 84(4)1176-83. doi: 10.1128/IAI.01202-15.

PMID:
    26857571
    [PubMed - in process]
Related citations


Subversion of Host Innate Immunity by Uropathogenic Escherichia coli.
Olson PD, Hunstad DA
Pathogens. 2016 Jan 4; 5(1)pii: E2. doi: 10.3390/pathogens5010002.

PMID:
    26742078
    [PubMed]
Related citations


A Murine Model for Escherichia coli Urinary Tract Infection.
Hannan TJ, Hunstad DA
Methods Mol Biol. 2016; 1333159-75. doi: 10.1007/978-1-4939-2854-5_14.

PMID:
    26468108
    [PubMed - in process]
Related citations


Androgens Enhance Male Urinary Tract Infection Severity in a New Model.
Olson PD, Hruska KA, Hunstad DA
J Am Soc Nephrol. 2015 Oct 8; pii: ASN.2015030327.

PMID:
    26449605
    [PubMed - as supplied by publisher]
Related citations


Klebsiella pneumoniae FimK Promotes Virulence in Murine Pneumonia.
Rosen DA, Hilliard JK, Tiemann KM, Todd EM, Morley SC, Hunstad DA
J Infect Dis. 2016 Feb 15; 213(4)649-58. doi: 10.1093/infdis/jiv440.

PMID:
    26347570
    [PubMed - in process]
Related citations


Imidazolium salts as small-molecule urinary bladder exfoliants in a murine model.
Wagers PO, Tiemann KM, Shelton KL, Kofron WG, Panzner MJ, Wooley KL, Youngs WJ, Hunstad DA
Antimicrob Agents Chemother. 2015 Sep; 59(9)5494-502. doi: 10.1128/AAC.00881-15.

PMID:
    26124168
    [PubMed - indexed for MEDLINE]
Related citations


Vitamin D sufficiency and Staphylococcus aureus infection in children.
Wang JW, Hogan PG, Hunstad DA, Fritz SA
Pediatr Infect Dis J. 2015 May; 34(5)544-5. doi: 10.1097/INF.0000000000000667.

PMID:
    25860535
    [PubMed - indexed for MEDLINE]
Related citations


Molecular Epidemiology of Recurrent Cutaneous Methicillin-Resistant Staphylococcus aureus Infections in Children.
Al-Zubeidi D, Burnham CA, Hogan PG, Collins R, Hunstad DA, Fritz SA
J Pediatric Infect Dis Soc. 2014 Sep; 3(3)261-4. doi: 10.1093/jpids/pit046.

PMID:
    25844165
    [PubMed]
Related citations


Preparation and in vitro antimicrobial activity of silver-bearing degradable polymeric nanoparticles of polyphosphoester-block-poly(L-lactide).
Lim YH, Tiemann KM, Heo GS, Wagers PO, Rezenom YH, Zhang S, Zhang F, Youngs WJ, Hunstad DA, Wooley KL
ACS Nano. 2015 Feb 24; 9(2)1995-2008. doi: 10.1021/nn507046h.

PMID:
    25621868
    [PubMed - indexed for MEDLINE]
Related citations


Cathelicidin augments epithelial receptivity and pathogenesis in experimental Escherichia coli cystitis.
Danka ES, Hunstad DA
J Infect Dis. 2015 Apr 1; 211(7)1164-73. doi: 10.1093/infdis/jiu577.

PMID:
    25336727
    [PubMed - indexed for MEDLINE]
Related citations


Bacterial lysis liberates the neutrophil migration suppressor YbcL from the periplasm of uropathogenic Escherichia coli.
Lau ME, Danka ES, Tiemann KM, Hunstad DA
Infect Immun. 2014 Dec; 82(12)4921-30. doi: 10.1128/IAI.01838-14.

PMID:
    25183735
    [PubMed - indexed for MEDLINE]
Related citations


Scurvy revealed by difficulty walking: three cases in young children.
Kitcharoensakkul M, Schulz CG, Kassel R, Khanna G, Liang S, Ngwube A, Baszis KW, Hunstad DA, White AJ
J Clin Rheumatol. 2014 Jun; 20(4)224-8. doi: 10.1097/RHU.0000000000000101.

PMID:
    24847751
    [PubMed - indexed for MEDLINE]
Related citations


Quantitative assessment of human neutrophil migration across a cultured bladder epithelium.
Lau ME, Hunstad DA
J Vis Exp. 2013 Nov 7; (81)e50919. doi: 10.3791/50919.

PMID:
    24300797
    [PubMed - indexed for MEDLINE]
Related citations


A Newborn With Hydrops, Hydrocephalus, and Ophthalmologic Abnormalities.
El Feghaly RE, Hunstad DA
J Pediatric Infect Dis Soc. 2013 Dec; 2(4)391-3. doi: 10.1093/jpids/pit047.

PMID:
    26619503
    [PubMed]
Related citations


Vancomycin trough concentrations in overweight or obese pediatric patients.
Heble DE Jr, McPherson C, Nelson MP, Hunstad DA
Pharmacotherapy. 2013 Dec; 33(12)1273-7. doi: 10.1002/phar.1321.

PMID:
    23798327
    [PubMed - indexed for MEDLINE]
Related citations


A serologic correlate of protective immunity against community-onset Staphylococcus aureus infection.
Fritz SA, Tiemann KM, Hogan PG, Epplin EK, Rodriguez M, Al-Zubeidi DN, Bubeck Wardenburg J, Hunstad DA
Clin Infect Dis. 2013 Jun; 56(11)1554-61. doi: 10.1093/cid/cit123.

PMID:
    23446627
    [PubMed - indexed for MEDLINE]
Related citations


YbcL of uropathogenic Escherichia coli suppresses transepithelial neutrophil migration.
Lau ME, Loughman JA, Hunstad DA
Infect Immun. 2012 Dec; 80(12)4123-32. doi: 10.1128/IAI.00801-12.

PMID:
    22966043
    [PubMed - indexed for MEDLINE]
Related citations


Oseltamivir dosing in premature infants.
McPherson C, Warner B, Hunstad DA, Elward A, Acosta EP
J Infect Dis. 2012 Sep 15; 206(6)847-50. doi: 10.1093/infdis/jis471.

PMID:
    22807525
    [PubMed - indexed for MEDLINE]
Related citations


Induction of indoleamine 2,3-dioxygenase by uropathogenic bacteria attenuates innate responses to epithelial infection.
Loughman JA, Hunstad DA
J Infect Dis. 2012 Jun 15; 205(12)1830-9. doi: 10.1093/infdis/jis280.

PMID:
    22474038
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Work in our laboratory focuses on the interactions of pathogenic bacteria with their hosts.  We aim to elucidate the modulation of host immune responses by pathogens and to determine the mechanisms by which these bacteria present specific virulence factors on their surfaces.  Our primary goal is to discover novel targets for interventions that will prevent and treat bacterial infections of the urinary tract, gastrointestinal tract, and central nervous system.  


Hunstad Lab Web Page