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Daniel Kreisel, MD, PhD

Professor, Surgery, Pathology & Immunology
Surgical Director, Lung Transplant Program
Division of Cardiothoracic Surgery

Specialty Areas

Thoracic Surgery
Lung Cancer
Lung Disease
Lung Transplantation
Thoracic Oncology

Board Certifications

General Surgery

Hospital Affiliations

Barnes-Jewish Hospital

Languages

German

Areas of Clinical Interest

General thoracic surgery, lung transplant, lung cancer, benign esophageal disease, emphysema, thoracic surgery

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Siteman Cancer Center - South County

5225 MidAmerica Plaza
St. Louis, MO 63129
Phone: 314-747-7222

Office Phone: 314-362-6021

Center for Advanced Medicine
Lung Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 8
Office Phone: 314-362-6021
Fax: 314-367-8459

Education

Education

Fellowship: Cardiothoracic Surgery, Washington University School of Medicine, St. Louis MO 2005
Chief Resident: General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 2003
Doctor of Philosophy: Immunology, Graduate Group, University of Pennsylvania, Philadelphia, Pennsylvania 2002
Residency: General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA 2002
Medical Degree: Mount Sinai School of Medicine, New York, NY 1995

Publication & Research

Publication & Research

Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1β.
Hsiao HM, Fernandez R, Tanaka S, Li W, Spahn JH, Chiu S, Akbarpour M, Ruiz-Perez D, Wu Q, Turam C, Scozzi D, Takahashi T, Luehmann HP, Puri V, Budinger GRS, Krupnick AS, Misharin AV, Lavine KJ, Liu Y, Gelman AE, Bharat A, Kreisel D
J Clin Invest. 2018 May 21; pii: 98436. doi: 10.1172/JCI98436.

PMID:
    29781811
    [PubMed - as supplied by publisher]
Related citations


Diagnosis, Pathophysiology and Experimental Models of Chronic Lung Allograft Rejection.
Gauthier JM, Ruiz-Pérez D, Li W, Hachem RR, Puri V, Gelman AE, Kreisel D
Transplantation. 2018 Apr 21; doi: 10.1097/TP.0000000000002250.

PMID:
    29683998
    [PubMed - as supplied by publisher]
Related citations


Visualization of Monocytic Cells in Regressing Atherosclerotic Plaques by Intravital 2-Photon and Positron Emission Tomography-Based Imaging-Brief Report.
Li W, Luehmann HP, Hsiao HM, Tanaka S, Higashikubo R, Gauthier JM, Sultan D, Lavine KJ, Brody SL, Gelman AE, Gropler RJ, Liu Y, Kreisel D
Arterioscler Thromb Vasc Biol. 2018 May; 38(5)1030-1036. doi: 10.1161/ATVBAHA.117.310517.

PMID:
    29567678
    [PubMed - in process]
Related citations


Immunopathogenesis of Primary Graft Dysfunction After Lung Transplantation.
Bharat A, Kreisel D
Ann Thorac Surg. 2018 Mar; 105(3)671-674. doi: 10.1016/j.athoracsur.2017.11.007.

PMID:
    29455798
    [PubMed - in process]
Related citations


Lung Focused Resuscitation at a Specialized Donor Care Facility Improves Lung Procurement Rates.
Chang SH, Kreisel D, Marklin GF, Cook L, Hachem R, Kozower BD, Balsara KR, Bell JM, Frederiksen C, Meyers BF, Patterson GA, Puri V
Ann Thorac Surg. 2018 May; 105(5)1531-1536. doi: 10.1016/j.athoracsur.2017.12.009.

PMID:
    29337122
    [PubMed - in process]
Related citations


Eosinophils promote inducible NOS-mediated lung allograft acceptance.
Onyema OO, Guo Y, Wang Q, Stoler MH, Lau C, Li K, Nazaroff CD, Wang X, Li W, Kreisel D, Gelman AE, Lee JJ, Jacobsen EA, Krupnick AS
JCI Insight. 2017 Dec 21; 2(24)pii: 96455. doi: 10.1172/jci.insight.96455.

PMID:
    29263310
    [PubMed - as supplied by publisher]
Related citations


Naive CD4<sup>+</sup> T Cells Carrying a TLR2 Agonist Overcome TGF-β-Mediated Tumor Immune Evasion.
Ibrahim M, Scozzi D, Toth KA, Ponti D, Kreisel D, Menna C, De Falco E, D'Andrilli A, Rendina EA, Calogero A, Krupnick AS, Gelman AE
J Immunol. 2018 Jan 15; 200(2)847-856. doi: 10.4049/jimmunol.1700396.

PMID:
    29212908
    [PubMed - in process]
Related citations


Office-Based Spirometry: A New Model of Care in Preoperative Assessment for Low-Risk Lung Resections.
Hudson JL, Bell JM, Crabtree TD, Kreisel D, Patterson GA, Meyers BF, Puri V
Ann Thorac Surg. 2018 Jan; 105(1)279-286. doi: 10.1016/j.athoracsur.2017.08.010.

PMID:
    29157739
    [PubMed - indexed for MEDLINE]
Related citations


Hitting the target with lung perfusion.
Gauthier JM, Puri V, Kreisel D
J Thorac Cardiovasc Surg. 2017 Nov; 154(5)1821-1822. doi: 10.1016/j.jtcvs.2017.08.009.

PMID:
    29042053
    [PubMed - in process]
Related citations


The role of C4d deposition in the diagnosis of antibody-mediated rejection after lung transplantation.
Aguilar PR, Carpenter D, Ritter J, Yusen RD, Witt CA, Byers DE, Mohanakumar T, Kreisel D, Trulock EP, Hachem RR
Am J Transplant. 2018 Apr; 18(4)936-944. doi: 10.1111/ajt.14534.

PMID:
    28992372
    [PubMed - in process]
Related citations


Mechanisms of Graft Rejection and Immune Regulation after Lung Transplant.
Gauthier JM, Li W, Hsiao HM, Takahashi T, Arefanian S, Krupnick AS, Gelman AE, Kreisel D
Ann Am Thorac Soc. 2017 Sep; 14(Supplement_3)S216-S219. doi: 10.1513/AnnalsATS.201607-576MG.

PMID:
    28945475
    [PubMed - indexed for MEDLINE]
Related citations


Endotracheal tube-induced sore throat pain and inflammation is coupled to the release of mitochondrial DNA.
Puyo CA, Peruzzi D, Earhart A, Roller E, Karanikolas M, Kollef MH, Krupnick AS, Kreisel D, Ibrahim M, Gelman AE
Mol Pain. 2017 Jan-Dec; 131744806917731696. doi: 10.1177/1744806917731696.

PMID:
    28929859
    [PubMed - in process]
Related citations


Impact of Delayed Chest Closure on Surgical Site Infection After Lung Transplantation.
Aguilar PR, Bemiss BC, Witt C, Byers DE, Kreisel D, Puri V, Meyers B, Patterson GA, Krupnick AS, Yusen RD, Trulock EP, Hachem RR
Ann Thorac Surg. 2017 Oct; 104(4)1208-1214. doi: 10.1016/j.athoracsur.2017.05.023.

PMID:
    28821338
    [PubMed - indexed for MEDLINE]
Related citations


Ex vivo lung perfusion: Perfusing less lung can yield more lungs.
Balsara KR, Puri V, Kreisel D
J Thorac Cardiovasc Surg. 2017 Nov; 154(5)e91-e92. doi: 10.1016/j.jtcvs.2017.07.007.

PMID:
    28784242
    [PubMed - in process]
Related citations


PD-1 expression on CD8<sup>+</sup> T cells regulates their differentiation within lung allografts and is critical for tolerance induction.
Takahashi T, Hsiao HM, Tanaka S, Li W, Higashikubo R, Scozzi D, Bharat A, Ritter JH, Krupnick AS, Gelman AE, Kreisel D
Am J Transplant. 2018 Jan; 18(1)216-225. doi: 10.1111/ajt.14437.

PMID:
    28730633
    [PubMed - in process]
Related citations


Donor pulmonary intravascular nonclassical monocytes recruit recipient neutrophils and mediate primary lung allograft dysfunction.
Zheng Z, Chiu S, Akbarpour M, Sun H, Reyfman PA, Anekalla KR, Abdala-Valencia H, Edgren D, Li W, Kreisel D, Korobova FV, Fernandez R, McQuattie-Pimentel A, Zhang ZJ, Perlman H, Misharin AV, Scott Budinger GR, Bharat A
Sci Transl Med. 2017 Jun 14; 9(394)pii: eaal4508. doi: 10.1126/scitranslmed.aal4508.

PMID:
    28615357
    [PubMed - indexed for MEDLINE]
Related citations


Models of Lung Transplant Research: a consensus statement from the National Heart, Lung, and Blood Institute workshop.
Lama VN, Belperio JA, Christie JD, El-Chemaly S, Fishbein MC, Gelman AE, Hancock WW, Keshavjee S, Kreisel D, Laubach VE, Looney MR, McDyer JF, Mohanakumar T, Shilling RA, Panoskaltsis-Mortari A, Wilkes DS, Eu JP, Nicolls MR
JCI Insight. 2017 May 4; 2(9)pii: 93121. doi: 10.1172/jci.insight.93121.

PMID:
    28469087
    [PubMed - as supplied by publisher]
Related citations


Adjuvant Chemotherapy Is Associated With Improved Survival in Locally Invasive Node Negative Non-Small Cell Lung Cancer.
Ahmad U, Crabtree TD, Patel AP, Morgensztern D, Robinson CG, Krupnick AS, Kreisel D, Jones DR, Patterson GA, Meyers BF, Puri V
Ann Thorac Surg. 2017 Jul; 104(1)303-307. doi: 10.1016/j.athoracsur.2017.01.069.

PMID:
    28433225
    [PubMed - indexed for MEDLINE]
Related citations


Deficiency of the adaptor protein SLy1 results in a natural killer cell ribosomopathy affecting tumor clearance.
Arefanian S, Schäll D, Chang S, Ghasemi R, Higashikubo R, Zheleznyak A, Guo Y, Yu J, Asgharian H, Li W, Gelman AE, Kreisel D, French AR, Zaher H, Plougastel-Douglas B, Maggi L, Yokoyama W, Beer-Hammer S, Krupnick AS
Oncoimmunology. 2016; 5(12)e1238543. doi: 10.1080/2162402X.2016.1238543.

PMID:
    28123874
    [PubMed]
Related citations


Defining the Ideal Time Interval Between Planned Induction Therapy and Surgery for Stage IIIA Non-Small Cell Lung Cancer.
Samson P, Crabtree TD, Robinson CG, Morgensztern D, Broderick S, Krupnick AS, Kreisel D, Patterson GA, Meyers B, Puri V
Ann Thorac Surg. 2017 Apr; 103(4)1070-1075. doi: 10.1016/j.athoracsur.2016.09.053.

PMID:
    28110809
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Transplantation immunology, tumor immunology, innate immunity and ischemia-reperfusion injury