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Daniel C. Brennan, MD

Professor, Medicine
Division of Nephrology
Director, Transplant Nephrology
Medical Director, Pharmacoeconomic Transplant Research

Specialty Areas

Internal Medicine
Transplant Nephrology
Kidney Disease
Nephrology

Board Certifications

Internal Medicine
Nephrology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Kidney transplant, CMV disease in renal transplantation, pharmacoeconomics, islet transplantation

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Medicine Multispecialty Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 5
Office Phone: 314-362-7603
Fax: 314-361-4197

Education

Education

Fellowship: Nephrology, Transplant Immunology & Transplantation Brigham & Women's Hosp, Boston, Massachusetts 1991
Fellowship: Nephrology, Harvard Medical School Brigham and Womens Hospital, Boston, Massachusetts 1992
Residency: University of Iowa Hospitals and Clinics, Iowa City, Iowa 1988
Medical Degree: University Of Iowa, Iowa City, Iowa 1985
B.S.: Cornell College, Mount Vernon, Iowa 1981

Publication & Research

Publication & Research

Singing a New SONG: Outcomes for Clinical Trials.
Malone AF, Brennan DC
Transplantation. 2017 Apr 11; doi: 10.1097/TP.0000000000001775.

PMID:
    28403129
    [PubMed - as supplied by publisher]
Related citations


The Privilege of Induction Avoidance and Calcineurin Inhibitors Withdrawal in 2 Haplotype HLA Matched White Kidney Transplantation.
Brifkani Z, Brennan DC, Lentine KL, Horwedel TA, Malone AF, Delos Santos R, Maw TT, Alhamad T
Transplant Direct. 2017 Mar; 3(3)e133. doi: 10.1097/TXD.0000000000000645.

PMID:
    28361117
    [PubMed - in process]
Related citations


Cell-Free DNA and Active Rejection in Kidney Allografts.
Bloom RD, Bromberg JS, Poggio ED, Bunnapradist S, Langone AJ, Sood P, Matas AJ, Mehta S, Mannon RB, Sharfuddin A, Fischbach B, Narayanan M, Jordan SC, Cohen D, Weir MR, Hiller D, Prasad P, Woodward RN, Grskovic M, Sninsky JJ, Yee JP, Brennan DC, Circulating Donor-Derived Cell-Free DNA in Blood for Diagnosing Active Rejection in Kidney Transplant Recipients (DART) Study Investigators.
J Am Soc Nephrol. 2017 Mar 9; pii: ASN.2016091034. doi: 10.1681/ASN.2016091034.

PMID:
    28280140
    [PubMed - as supplied by publisher]
Related citations


Complete Genome Sequence of BK Polyomavirus Subtype Ib-1 Detected in a Kidney Transplant Patient with BK Viremia Using Shotgun Sequencing.
Ranjan R, Rani A, Brennan DC, Finn PW, Perkins DL
Genome Announc. 2017 Feb 9; 5(6)pii: e01474-16. doi: 10.1128/genomeA.01474-16.

PMID:
    28183780
    [PubMed - in process]
Related citations


Transplant Center Volume and the Risk of Pancreas Allograft Failure.
Alhamad T, Malone AF, Brennan DC, Stratta RJ, Chang SH, Wellen JR, Horwedel TA, Lentine KL
Transplantation. 2017 Jan 17; doi: 10.1097/TP.0000000000001628.

PMID:
    28099402
    [PubMed - as supplied by publisher]
Related citations


Epstein-Barr virus and renal transplantation.
Le J, Durand CM, Agha I, Brennan DC
Transplant Rev (Orlando). 2017 Jan; 31(1)55-60. doi: 10.1016/j.trre.2016.12.001.

PMID:
    28089555
    [PubMed - in process]
Related citations


Letermovir for the management of cytomegalovirus infection.
Bowman LJ, Melaragno JI, Brennan DC
Expert Opin Investig Drugs. 2017 Feb; 26(2)235-241. doi: 10.1080/13543784.2017.1274733.

PMID:
    27998189
    [PubMed - indexed for MEDLINE]
Related citations


Ureteral stent placement and immediate graft function are associated with increased risk of BK viremia in the first year after kidney transplantation.
Maliakkal JG, Brennan DC, Goss C, Horwedel TA, Chen H, Fong DK, Agarwal N, Zheng J, Schechtman KB, Dharnidharka VR
Transpl Int. 2017 Feb; 30(2)153-161. doi: 10.1111/tri.12888.

PMID:
    27862417
    [PubMed - in process]
Related citations


Polyomavirus Reactivation and Immune Responses to Kidney-Specific Self-Antigens in Transplantation.
Seifert ME, Gunasekaran M, Horwedel TA, Daloul R, Storch GA, Mohanakumar T, Brennan DC
J Am Soc Nephrol. 2017 Apr; 28(4)1314-1325. doi: 10.1681/ASN.2016030285.

PMID:
    27821629
    [PubMed - indexed for MEDLINE]
Related citations


Differential risks for adverse outcomes 3 years after kidney transplantation based on initial immunosuppression regimen: a national study.
Dharnidharka VR, Schnitzler MA, Chen J, Brennan DC, Axelrod D, Segev DL, Schechtman KB, Zheng J, Lentine KL
Transpl Int. 2016 Nov; 29(11)1226-1236. doi: 10.1111/tri.12850.

PMID:
    27564782
    [PubMed - in process]
Related citations


A Snapshot of Antibody-Mediated Rejection Goes Viral.
Lim ES, Brennan DC
Transplantation. 2017 Feb; 101(2)227. doi: 10.1097/TP.0000000000001540.

PMID:
    27779575
    [PubMed - in process]
Related citations


Introduction: Kidney Transplantation and Viral Infection.
Brennan DC
Semin Nephrol. 2016 Sep; 36(5)343. doi: 10.1016/j.semnephrol.2016.05.010.

PMID:
    27772618
    [PubMed - in process]
Related citations


Urinary microbiome of kidney transplant patients reveals dysbiosis with potential for antibiotic resistance.
Rani A, Ranjan R, McGee HS, Andropolis KE, Panchal DV, Hajjiri Z, Brennan DC, Finn PW, Perkins DL
Transl Res. 2017 Mar; 18159-70. doi: 10.1016/j.trsl.2016.08.008.

PMID:
    27669488
    [PubMed - indexed for MEDLINE]
Related citations


A diverse virome in kidney transplant patients contains multiple viral subtypes with distinct polymorphisms.
Rani A, Ranjan R, McGee HS, Metwally A, Hajjiri Z, Brennan DC, Finn PW, Perkins DL
Sci Rep. 2016 Sep 16; 633327. doi: 10.1038/srep33327.

PMID:
    27633952
    [PubMed - in process]
Related citations


Predonation Prescription Opioid Use: A Novel Risk Factor for Readmission After Living Kidney Donation.
Lentine KL, Lam NN, Schnitzler MA, Hess GP, Kasiske BL, Xiao H, Axelrod D, Garg AX, Schold JD, Randall H, Dzebisashvili N, Brennan DC, Segev DL
Am J Transplant. 2017 Mar; 17(3)744-753. doi: 10.1111/ajt.14033.

PMID:
    27589826
    [PubMed - in process]
Related citations


The Changing Financial Landscape of Renal Transplant Practice: A National Cohort Analysis.
Axelrod DA, Schnitzler MA, Xiao H, Naik AS, Segev DL, Dharnidharka VR, Brennan DC, Lentine KL
Am J Transplant. 2017 Feb; 17(2)377-389. doi: 10.1111/ajt.14018.

PMID:
    27565133
    [PubMed - in process]
Related citations


Clinical and Economic Consequences of Early Cancer After Kidney Transplantation in Contemporary Practice.
Dharnidharka VR, Naik AS, Axelrod D, Schnitzler MA, Xiao H, Brennan DC, Segev DL, Randall H, Chen J, Kasiske B, Lentine KL
Transplantation. 2017 Apr; 101(4)858-866. doi: 10.1097/TP.0000000000001385.

PMID:
    27490413
    [PubMed - indexed for MEDLINE]
Related citations


Diabetes Mellitus in Living Pancreas Donors: Use of Integrated National Registry and Pharmacy Claims Data to Characterize Donation-Related Health Outcomes.
Lam NN, Schnitzler MA, Segev DL, Hess GP, Kasiske BL, Randall HB, Axelrod D, Xiao H, Garg AX, Brennan DC, Lentine KL
Transplantation. 2017 Jun; 101(6)1276-1281. doi: 10.1097/TP.0000000000001375.

PMID:
    27482962
    [PubMed - in process]
Related citations


Selected Mildly Obese Donors Can Be Used Safely in Simultaneous Pancreas and Kidney Transplantation.
Alhamad T, Malone AF, Lentine KL, Brennan DC, Wellen J, Chang SH, Chakkera HA
Transplantation. 2017 Jun; 101(6)1159-1166. doi: 10.1097/TP.0000000000001303.

PMID:
    27428713
    [PubMed - in process]
Related citations


Pretransplant Midodrine Use: A Newly Identified Risk Marker for Complications After Kidney Transplantation.
Alhamad T, Brennan DC, Brifkani Z, Xiao H, Schnitzler MA, Dharnidharka VR, Axelrod D, Segev DL, Lentine KL
Transplantation. 2016 May; 100(5)1086-93. doi: 10.1097/TP.0000000000001113.

PMID:
    26950718
    [PubMed - indexed for MEDLINE]
Related citations