Patient Portal

Christopher D. Smyser, MD

Associate Professor, Neurology
Division of Pediatric Neurology

Specialty Areas

Pediatric Neurology
Neonatal Neurology
Pediatric Stroke

Board Certifications

Pediatric Neurology

Hospital Affiliations

St. Louis Children's Hospital

Areas of Clinical Interest

Neonatal neurology, pediatric stroke, cerebral palsy, CNS malformations, developmental disorders, general pediatric neurology.

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Office Phone: 314-454-6120
Fax: 314-454-2523

Education

Education

B.S.: Biomedical Engineering, University of Iowa College of Medicine, Iowa City, IA 1998
Medical Degree: University of Iowa College of Medicine, Iowa City, Iowa 2004
Residency: Child Neurology, Washington University School of Medicine/ St. Louis Children's Hospital, St. Louis, Missouri 2009
Residency: Pediatrics, University of Iowa College of Medicine, Iowa City, Iowa 2006
Chief Resident: Neurology, Washington University School of Medicine, St. Louis, Missouri 2009

Publication & Research

Publication & Research

Prenatal to postnatal trajectory of brain growth in complex congenital heart disease.
Ortinau CM, Mangin-Heimos K, Moen J, Alexopoulos D, Inder TE, Gholipour A, Shimony JS, Eghtesady P, Schlaggar BL, Smyser CD
Neuroimage Clin. 2018; 20913-922. doi: 10.1016/j.nicl.2018.09.029.

PMID:
    30308377
    [PubMed - in process]
Related citations


Social Adversity and Cognitive, Language, and Motor Development of Very Preterm Children from 2 to 5 Years of Age.
Lean RE, Paul RA, Smyser TA, Smyser CD, Rogers CE
J Pediatr. 2018 Dec; 203177-184.e1. doi: 10.1016/j.jpeds.2018.07.110.

PMID:
    30244986
    [PubMed - in process]
Related citations


Altered functional network connectivity relates to motor development in children born very preterm.
Wheelock MD, Austin NC, Bora S, Eggebrecht AT, Melzer TR, Woodward LJ, Smyser CD
Neuroimage. 2018 Dec; 183574-583. doi: 10.1016/j.neuroimage.2018.08.051.

PMID:
    30144569
    [PubMed - in process]
Related citations


Neonatal brain injury and aberrant connectivity.
Smyser CD, Wheelock MD, Limbrick DD Jr, Neil JJ
Neuroimage. 2018 Jul 27; pii: S1053-8119(18)30672-4. doi: 10.1016/j.neuroimage.2018.07.057.

PMID:
    30059733
    [PubMed - as supplied by publisher]
Related citations


Predictors of mortality for preterm infants with intraventricular hemorrhage: a population-based study.
Han RH, McKinnon A, CreveCoeur TS, Baksh BS, Mathur AM, Smyser CD, Strahle JM, Olsen MA, Limbrick DD Jr
Childs Nerv Syst. 2018 Jul 9; doi: 10.1007/s00381-018-3897-4.

PMID:
    29987373
    [PubMed - as supplied by publisher]
Related citations


Recent advances in the use of MRI to assess early human cortical development.
Neil JJ, Smyser CD
J Magn Reson. 2018 Aug; 29356-69. doi: 10.1016/j.jmr.2018.05.013.

PMID:
    29894905
    [PubMed - in process]
Related citations


Term-equivalent functional brain maturational measures predict neurodevelopmental outcomes in premature infants.
El Ters NM, Vesoulis ZA, Liao SM, Smyser CD, Mathur AM
Early Hum Dev. 2018 Apr; 11968-72. doi: 10.1016/j.earlhumdev.2018.02.010.

PMID:
    29579560
    [PubMed - in process]
Related citations


Dynamic patterns of cortical expansion during folding of the preterm human brain.
Garcia KE, Robinson EC, Alexopoulos D, Dierker DL, Glasser MF, Coalson TS, Ortinau CM, Rueckert D, Taber LA, Van Essen DC, Rogers CE, Smyser CD, Bayly PV
Proc Natl Acad Sci U S A. 2018 Mar 20; 115(12)3156-3161. doi: 10.1073/pnas.1715451115.

PMID:
    29507201
    [PubMed - indexed for MEDLINE]
Related citations


Cerebellar Functional Connectivity in Term- and Very Preterm-Born Infants.
Herzmann CS, Snyder AZ, Kenley JK, Rogers CE, Shimony JS, Smyser CD
Cereb Cortex. 2018 Feb 6; doi: 10.1093/cercor/bhy023.

PMID:
    29420701
    [PubMed - as supplied by publisher]
Related citations


Differential Rates of Perinatal Maturation of Human Primary and Nonprimary Auditory Cortex.
Monson BB, Eaton-Rosen Z, Kapur K, Liebenthal E, Brownell A, Smyser CD, Rogers CE, Inder TE, Warfield SK, Neil JJ
eNeuro. 2018 Jan-Feb; 5(1)pii: ENEURO.0380-17.2017. doi: 10.1523/ENEURO.0380-17.2017.

PMID:
    29354680
    [PubMed - in process]
Related citations


Brain growth in the NICU: critical periods of tissue-specific expansion.
Matthews LG, Walsh BH, Knutsen C, Neil JJ, Smyser CD, Rogers CE, Inder TE
Pediatr Res. 2018 May; 83(5)976-981. doi: 10.1038/pr.2018.4.

PMID:
    29320484
    [PubMed - in process]
Related citations


Intraventricular Hemorrhage in Moderate to Severe Congenital Heart Disease.
Ortinau CM, Anadkat JS, Smyser CD, Eghtesady P
Pediatr Crit Care Med. 2018 Jan; 19(1)56-63. doi: 10.1097/PCC.0000000000001374.

PMID:
    29210924
    [PubMed - in process]
Related citations


Maternal intelligence quotient (IQ) predicts IQ and language in very preterm children at age 5 years.
Lean RE, Paul RA, Smyser CD, Rogers CE
J Child Psychol Psychiatry. 2018 Feb; 59(2)150-159. doi: 10.1111/jcpp.12810.

PMID:
    28925538
    [PubMed - in process]
Related citations


Time-to-event analysis of surgically treated posthemorrhagic hydrocephalus in preterm infants: a single-institution retrospective study.
Han RH, Berger D, Gabir M, Baksh BS, Morales DM, Mathur AM, Smyser CD, Strahle JM, Limbrick DD Jr
Childs Nerv Syst. 2017 Nov; 33(11)1917-1926. doi: 10.1007/s00381-017-3588-6.

PMID:
    28884229
    [PubMed - indexed for MEDLINE]
Related citations


Cortical Functional Connectivity Evident After Birth and Behavioral Inhibition at Age 2.
Sylvester CM, Smyser CD, Smyser T, Kenley J, Ackerman JJ Jr, Shimony JS, Petersen SE, Rogers CE
Am J Psychiatry. 2018 Feb 1; 175(2)180-187. doi: 10.1176/appi.ajp.2017.17010018.

PMID:
    28774192
    [PubMed - indexed for MEDLINE]
Related citations


Assessment: The Newborn.
Lean RE, Smyser CD, Rogers CE
Child Adolesc Psychiatr Clin N Am. 2017 Jul; 26(3)427-440. doi: 10.1016/j.chc.2017.02.002.

PMID:
    28577601
    [PubMed - indexed for MEDLINE]
Related citations


Impact of brain injury on functional measures of amplitude-integrated EEG at term equivalent age in premature infants.
El Ters NM, Vesoulis ZA, Liao SM, Smyser CD, Mathur AM
J Perinatol. 2017 Aug; 37(8)947-952. doi: 10.1038/jp.2017.62.

PMID:
    28492522
    [PubMed - indexed for MEDLINE]
Related citations


Neonatal Amygdala Functional Connectivity at Rest in Healthy and Preterm Infants and Early Internalizing Symptoms.
Rogers CE, Sylvester CM, Mintz C, Kenley JK, Shimony JS, Barch DM, Smyser CD
J Am Acad Child Adolesc Psychiatry. 2017 Feb; 56(2)157-166. doi: 10.1016/j.jaac.2016.11.005.

PMID:
    28117062
    [PubMed - indexed for MEDLINE]
Related citations


Safety and Short-Term Outcomes of Therapeutic Hypothermia in Preterm Neonates 34-35 Weeks Gestational Age with Hypoxic-Ischemic Encephalopathy.
Rao R, Trivedi S, Vesoulis Z, Liao SM, Smyser CD, Mathur AM
J Pediatr. 2017 Apr; 18337-42. doi: 10.1016/j.jpeds.2016.11.019.

PMID:
    27979578
    [PubMed - indexed for MEDLINE]
Related citations


Neurologic Injury in Acidemic Term Infants.
Cahill AG, Mathur AM, Smyser CD, Mckinstry RC, Roehl KA, López JD, Inder TE, Macones GA
Am J Perinatol. 2017 Jun; 34(7)668-675. doi: 10.1055/s-0036-1597135.

PMID:
    27926973
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Project mapping structural connections within and between systems in the neonatal brain through collection and analysis of functional connectivity MRI data (2007-current).