Patient Portal

Christina Tsien, MD

Professor, Radiation Oncology
Chief, Central Nervouse System (CNS) Service
Director, Clinical Research

Specialty Areas

Radiation Oncology
Brain Tumors
Gamma Knife
Neuro Oncology
Proton Therapy
Stereotactic Body Radiation Therepy
Intensity Modulated Radiation Therapy ( IMRT)

Board Certifications

Radiation Oncology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Brain tumors, gamma knife, proton therapy, stereotactic body radiation therapy

  • Location(s)
  • Education
  • Publication & Research

Location(s)

Location(s)

Center for Advanced Medicine

4921 Parkview Place
St. Louis, MO 63110

Suite: LL
Office Phone: 314-747-7236
Fax: 314-362-8521

Education

Education

Medical Degree: McGill University Faculty of Medicine, Montreal, Canada 1995
Residency, Radiation Oncology: McGill University Health Center, Montreal, Canada 2000
Fellowship, Radiation Oncology: University of Michigan, Ann Arbor, MI 2001

Publication & Research

Publication & Research

Dose-intensified chemoradiation is associated with altered patterns of failure and favorable survival in patients with newly diagnosed glioblastoma.
Kim MM, Speers C, Li P, Schipper M, Junck L, Leung D, Orringer D, Heth J, Umemura Y, Spratt DE, Wahl DR, Cao Y, Lawrence TS, Tsien CI
J Neurooncol. 2019 Apr 11; doi: 10.1007/s11060-019-03166-3.

PMID:
    30977058
    [PubMed - as supplied by publisher]
Related citations


NRG brain tumor specialists consensus guidelines for glioblastoma contouring.
Kruser TJ, Bosch WR, Badiyan SN, Bovi JA, Ghia AJ, Kim MM, Solanki AA, Sachdev S, Tsien C, Wang TJC, Mehta MP, McMullen KP
J Neurooncol. 2019 Mar 19; doi: 10.1007/s11060-019-03152-9.

PMID:
    30888558
    [PubMed - as supplied by publisher]
Related citations


Comparison of Voxel-Wise and Histogram Analyses of Glioma ADC Maps for Prediction of Early Therapeutic Change.
Chenevert TL, Malyarenko DI, Galbán CJ, Gomez-Hassan DM, Sundgren PC, Tsien CI, Ross BD
Tomography. 2019 Mar; 5(1)7-14. doi: 10.18383/j.tom.2018.00049.

PMID:
    30854437
    [PubMed]
Related citations


NCTN Assessment on Current Applications of Radiomics in Oncology.
Nie K, Al-Hallaq H, Li XA, Benedict SH, Sohn JW, Moran JM, Fan Y, Huang M, Knopp MV, Michalski JM, Monroe J, Obcemea C, Tsien CI, Solberg T, Wu J, Xia P, Xiao Y, El Naqa I
Int J Radiat Oncol Biol Phys. 2019 Jan 31; pii: S0360-3016(19)30178-6. doi: 10.1016/j.ijrobp.2019.01.087.

PMID:
    30711529
    [PubMed - as supplied by publisher]
Related citations


Phase 2 Study of Radiation Therapy Plus Low-Dose Temozolomide Followed by Temozolomide and Irinotecan for Glioblastoma: NRG Oncology RTOG Trial 0420.
Lieberman FS, Wang M, Robins HI, Tsien CI, Curran WJ Jr, Werner-Wasik M, Smith RP, Schultz C, Hartford AC, Zhang P, Mehta MP
Int J Radiat Oncol Biol Phys. 2019 Mar 15; 103(4)878-886. doi: 10.1016/j.ijrobp.2018.11.008.

PMID:
    30496882
    [PubMed - in process]
Related citations


Analysis of point mutations and copy number variation in Grade II and III meningioma.
McNulty SN, Schwetye K, Goldstein M, Carter J, Schmidt RE, Ansstas G, Tsien CI, Kim AH, Dahiya S
Exp Mol Pathol. 2018 Dec; 105(3)328-333. doi: 10.1016/j.yexmp.2018.10.007.

PMID:
    30316860
    [PubMed - indexed for MEDLINE]
Related citations


Late Effects of Radiation Prime the Brain Microenvironment for Accelerated Tumor Growth.
Duan C, Yang R, Yuan L, Engelbach JA, Tsien CI, Rich KM, Dahiya SM, Johanns TM, Ackerman JJH, Garbow JR
Int J Radiat Oncol Biol Phys. 2019 Jan 1; 103(1)190-194. doi: 10.1016/j.ijrobp.2018.08.033.

PMID:
    30171879
    [PubMed - in process]
Related citations


Radiologic Response and Disease Control of Recurrent Intracranial Meningiomas Treated With Reirradiation.
Lin AJ, Hui C, Dahiya S, Lu HC, Kim AH, Campian JL, Tsien C, Zipfel GJ, Rich KM, Chicoine M, Huang J
Int J Radiat Oncol Biol Phys. 2018 Sep 1; 102(1)194-203. doi: 10.1016/j.ijrobp.2018.05.011.

PMID:
    29970312
    [PubMed - in process]
Related citations


A rapid, computational approach for assessing interfraction esophageal motion for use in stereotactic body radiation therapy planning.
Cardenas ML, Mazur TR, Tsien CI, Green OL
Adv Radiat Oncol. 2018 Apr-Jun; 3(2)209-215. doi: 10.1016/j.adro.2017.10.003.

PMID:
    29904747
    [PubMed]
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Internal dose escalation is associated with increased local control for non-small cell lung cancer (NSCLC) brain metastases treated with stereotactic radiosurgery (SRS).
Abraham C, Garsa A, Badiyan SN, Drzymala R, Yang D, DeWees T, Tsien C, Dowling JL, Rich KM, Chicoine MR, Kim AH, Leuthardt EC, Robinson C
Adv Radiat Oncol. 2018 Apr-Jun; 3(2)146-153. doi: 10.1016/j.adro.2017.11.003.

PMID:
    29904739
    [PubMed]
Related citations


Progression of Low-Grade Glioma During Pregnancy With Subsequent Regression Postpartum Without Treatment-A Case Report.
Shah AS, Nicoletti LK, Kurtovic E, Tsien CI, Benzinger TLS, Chicoine MR
Neurosurgery. 2018 May 21; doi: 10.1093/neuros/nyy191.

PMID:
    29788426
    [PubMed - as supplied by publisher]
Related citations


Preclinical MRI: Studies of the irradiated brain.
Garbow JR, Tsien CI, Beeman SC
J Magn Reson. 2018 Jul; 29273-81. doi: 10.1016/j.jmr.2018.03.011.

PMID:
    29705034
    [PubMed - in process]
Related citations


Effect of Radiation Treatment Volume Reduction on Lymphopenia in Patients Receiving Chemoradiotherapy for Glioblastoma.
Rudra S, Hui C, Rao YJ, Samson P, Lin AJ, Chang X, Tsien C, Fergus S, Mullen D, Yang D, Thotala D, Hallahan D, Campian JL, Huang J
Int J Radiat Oncol Biol Phys. 2018 May 1; 101(1)217-225. doi: 10.1016/j.ijrobp.2018.01.069.

PMID:
    29502931
    [PubMed - indexed for MEDLINE]
Related citations


Inhibitors of HIF-1α and CXCR4 Mitigate the Development of Radiation Necrosis in Mouse Brain.
Yang R, Duan C, Yuan L, Engelbach JA, Tsien CI, Beeman SC, Perez-Torres CJ, Ge X, Rich KM, Ackerman JJH, Garbow JR
Int J Radiat Oncol Biol Phys. 2018 Mar 15; 100(4)1016-1025. doi: 10.1016/j.ijrobp.2017.12.257.

PMID:
    29485043
    [PubMed - indexed for MEDLINE]
Related citations


Completion of Gamma Knife radiosurgery for AVM treatment after unplanned interruption-technical note.
Raman HS, Santanam L, Vellimana AK, Drzymala RE, Tsien CI, Zipfel GJ
Acta Neurochir (Wien). 2018 Jul; 160(7)1343-1347. doi: 10.1007/s00701-018-3493-0.

PMID:
    29455411
    [PubMed - in process]
Related citations


Standard dose and dose-escalated radiation therapy are associated with favorable survival in select elderly patients with newly diagnosed glioblastoma.
Jackson WC, Tsien CI, Junck L, Leung D, Hervey-Jumper S, Orringer D, Heth J, Wahl DR, Spratt DE, Cao Y, Lawrence TS, Kim MM
J Neurooncol. 2018 May; 138(1)155-162. doi: 10.1007/s11060-018-2782-z.

PMID:
    29388034
    [PubMed - indexed for MEDLINE]
Related citations


Final results of a phase I dose-escalation, dose-expansion study of adding disulfiram with or without copper to adjuvant temozolomide for newly diagnosed glioblastoma.
Huang J, Campian JL, Gujar AD, Tsien C, Ansstas G, Tran DD, DeWees TA, Lockhart AC, Kim AH
J Neurooncol. 2018 May; 138(1)105-111. doi: 10.1007/s11060-018-2775-y.

PMID:
    29374809
    [PubMed - indexed for MEDLINE]
Related citations


Correction to expert consensus on re-irradiation for recurrent glioma.
Krauze AV, Attia A, Braunstein S, Chan M, Combs SE, Fietkau R, Fiveash J, Flickinger J, Grosu A, Howard S, Nieder C, Niyazi M, Rowe L, Smart DD, Tsien C, Camphausen K
Radiat Oncol. 2018 Jan 18; 13(1)8. doi: 10.1186/s13014-018-0955-8.

PMID:
    29347964
    [PubMed]
Related citations


Distant intracranial failure in melanoma brain metastases treated with stereotactic radiosurgery in the era of immunotherapy and targeted agents.
Acharya S, Mahmood M, Mullen D, Yang D, Tsien CI, Huang J, Perkins SM, Rich K, Chicoine M, Leuthardt E, Dowling J, Dunn G, Keller J, Robinson CG, Abraham C
Adv Radiat Oncol. 2017 Oct-Dec; 2(4)572-580. doi: 10.1016/j.adro.2017.07.003.

PMID:
    29204524
    [PubMed]
Related citations


Expert consensus on re-irradiation for recurrent glioma.
Krauze AV, Attia A, Braunstein S, Chan M, Combs SE, Fietkau R, Fiveash J, Flickinger J, Grosu A, Howard S, Nieder C, Niyazi M, Rowe L, Smart DD, Tsien C, Camphausen K
Radiat Oncol. 2017 Dec 1; 12(1)194. doi: 10.1186/s13014-017-0928-3.

PMID:
    29195507
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Glioblastoma radiation therapy treatment. Imaging biomarkers to improve tumor response assessment and to reduce normal tissue toxicity. Translational research for brain metastases and recurrent glioblastoma.