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Charles F. Zorumski, MD

Samuel B. Guze Professor and Head of Psychiatry
Professor of Neurobiology

Specialty Areas

Adult Psychiatry

Board Certifications

Psychiatry

Hospital Affiliations

Barnes-Jewish Hospital

Referral Information

Not Accepting New Patients

Areas of Clinical Interest

Electroconvulsive therapy, brain stimulation methods, electrophysiology, exitotoxic neuronal damage and neuropsychiatric disorders

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Barnes-Jewish Hospital (South)
Renard Hospital Building

4940 Children's Place
St. Louis, MO 63110

Suite: Room 2208
Office Phone: 314-747-2680
Fax: 314-747-2682

Education

Education

Residency: Washington University School of Medicine, St. Louis, Missouri 1982
Medical Degree: St. Louis University, St. Louis, Missouri 1978
Bachelor of Art: St. Louis University, St. Louis, Missouri 1974

Publication & Research

Publication & Research

Neuregulin and Dopamine D4 Receptors Contribute Independently to Depotentiation of Schaffer Collateral LTP by Temperoammonic Path Stimulation.
Izumi Y, Zorumski CF
eNeuro. 2017 Jul-Aug; 4(4)pii: ENEURO.0176-17.2017. doi: 10.1523/ENEURO.0176-17.2017.

PMID:
    28828402
    [PubMed - in process]
Related citations


The role of T-type calcium channels in the subiculum: to burst or not to burst?
Joksimovic SM, Eggan P, Izumi Y, Joksimovic SL, Tesic V, Dietz RM, Orfila JE, DiGruccio MR, Herson PS, Jevtovic-Todorovic V, Zorumski CF, Todorovic SM
J Physiol. 2017 Oct 1; 595(19)6327-6348. doi: 10.1113/JP274565.

PMID:
    28744923
    [PubMed - in process]
Related citations


Hippocampal slice preparation in rats acutely suppresses immunoreactivity of microtubule-associated protein (Map2) and glycogen levels without affecting numbers of glia or levels of the glutamate transporter VGlut1.
Stein LR, Zorumski CF, Izumi Y
Brain Behav. 2017 Jul; 7(7)e00736. doi: 10.1002/brb3.736.

PMID:
    28729941
    [PubMed - in process]
Related citations


Contributions of space-clamp errors to apparent time-dependent loss of Mg<sup>2+</sup> block induced by NMDA.
Sun MY, Chisari M, Eisenman LN, Zorumski CF, Mennerick SJ
J Neurophysiol. 2017 Jul 1; 118(1)532-543. doi: 10.1152/jn.00106.2017.

PMID:
    28356471
    [PubMed - in process]
Related citations


24S-hydroxycholesterol and 25-hydroxycholesterol differentially impact hippocampal neuronal survival following oxygen-glucose deprivation.
Sun MY, Taylor A, Zorumski CF, Mennerick S
PLoS One. 2017; 12(3)e0174416. doi: 10.1371/journal.pone.0174416.

PMID:
    28346482
    [PubMed - indexed for MEDLINE]
Related citations


Use of Ketamine in Clinical Practice: A Time for Optimism and Caution.
Zorumski CF, Conway CR
JAMA Psychiatry. 2017 Apr 1; 74(4)405-406. doi: 10.1001/jamapsychiatry.2017.0078.

PMID:
    28249064
    [PubMed - in process]
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High-sensitivity Cardiac Troponin Elevation after Electroconvulsive Therapy: A Prospective, Observational Cohort Study.
Duma A, Pal S, Johnston J, Helwani MA, Bhat A, Gill B, Rosenkvist J, Cartmill C, Brown F, Miller JP, Scott MG, Sanchez-Conde F, Jarvis M, Farber NB, Zorumski CF, Conway C, Nagele P
Anesthesiology. 2017 Apr; 126(4)643-652. doi: 10.1097/ALN.0000000000001531.

PMID:
    28166110
    [PubMed - indexed for MEDLINE]
Related citations


A Clickable Analogue of Ketamine Retains NMDA Receptor Activity, Psychoactivity, and Accumulates in Neurons.
Emnett C, Li H, Jiang X, Benz A, Boggiano J, Conyers S, Wozniak DF, Zorumski CF, Reichert DE, Mennerick S
Sci Rep. 2016 Dec 16; 638808. doi: 10.1038/srep38808.

PMID:
    27982047
    [PubMed - in process]
Related citations


Ketamine: NMDA Receptors and Beyond.
Zorumski CF, Izumi Y, Mennerick S
J Neurosci. 2016 Nov 2; 36(44)11158-11164.

PMID:
    27807158
    [PubMed - indexed for MEDLINE]
Related citations


24(S)-Hydroxycholesterol protects the ex vivo rat retina from injury by elevated hydrostatic pressure.
Ishikawa M, Yoshitomi T, Zorumski CF, Izumi Y
Sci Rep. 2016 Sep 22; 633886. doi: 10.1038/srep33886.

PMID:
    27653972
    [PubMed - as supplied by publisher]
Related citations


TSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model.
Ishikawa M, Yoshitomi T, Covey DF, Zorumski CF, Izumi Y
Neuropharmacology. 2016 Dec; 111142-159. doi: 10.1016/j.neuropharm.2016.09.001.

PMID:
    27596950
    [PubMed - indexed for MEDLINE]
Related citations


Effect of electrical parameters on ECT convulsive threshold and duration.
Isenberg KE, Dinwiddie S, Heath AC, Osborne V, Tepper M, Jarvis M, Spitznagel EL, Zorumski CF, North CS
Ann Clin Psychiatry. 2016 May; 28(2)105-16.

PMID:
    27285391
    [PubMed - in process]
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Short-term environmental enrichment enhances synaptic plasticity in hippocampal slices from aged rats.
Stein LR, O'Dell KA, Funatsu M, Zorumski CF, Izumi Y
Neuroscience. 2016 Aug 4; 329294-305. doi: 10.1016/j.neuroscience.2016.05.020.

PMID:
    27208617
    [PubMed - indexed for MEDLINE]
Related citations


A clickable neurosteroid photolabel reveals selective Golgi compartmentalization with preferential impact on proximal inhibition.
Jiang X, Shu HJ, Krishnan K, Qian M, Taylor AA, Covey DF, Zorumski CF, Mennerick S
Neuropharmacology. 2016 Sep; 108193-206. doi: 10.1016/j.neuropharm.2016.04.031.

PMID:
    27114255
    [PubMed - indexed for MEDLINE]
Related citations


GABA and Endocannabinoids Mediate Depotentiation of Schaffer Collateral Synapses Induced by Stimulation of Temperoammonic Inputs.
Izumi Y, Zorumski CF
PLoS One. 2016; 11(2)e0149034. doi: 10.1371/journal.pone.0149034.

PMID:
    26862899
    [PubMed - indexed for MEDLINE]
Related citations


Endogenous 24S-hydroxycholesterol modulates NMDAR-mediated function in hippocampal slices.
Sun MY, Izumi Y, Benz A, Zorumski CF, Mennerick S
J Neurophysiol. 2016 Mar; 115(3)1263-72. doi: 10.1152/jn.00890.2015.

PMID:
    26745248
    [PubMed - indexed for MEDLINE]
Related citations


Treatment-Resistant Major Depression: Rationale for NMDA Receptors as Targets and Nitrous Oxide as Therapy.
Zorumski CF, Nagele P, Mennerick S, Conway CR
Front Psychiatry. 2015; 6172. doi: 10.3389/fpsyt.2015.00172.

PMID:
    26696909
    [PubMed]
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Nampt is required for long-term depression and the function of GluN2B subunit-containing NMDA receptors.
Stein LR, Zorumski CF, Imai S, Izumi Y
Brain Res Bull. 2015 Oct; 119(Pt A)41-51. doi: 10.1016/j.brainresbull.2015.10.005.

PMID:
    26481044
    [PubMed - indexed for MEDLINE]
Related citations


Corticosterone enhances the potency of ethanol against hippocampal long-term potentiation via local neurosteroid synthesis.
Izumi Y, O'Dell KA, Zorumski CF
Front Cell Neurosci. 2015; 9254. doi: 10.3389/fncel.2015.00254.

PMID:
    26190975
    [PubMed]
Related citations


Experimentally Induced Mammalian Models of Glaucoma.
Ishikawa M, Yoshitomi T, Zorumski CF, Izumi Y
Biomed Res Int. 2015; 2015281214. doi: 10.1155/2015/281214.

PMID:
    26064891
    [PubMed - indexed for MEDLINE]
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