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Carlos Bernal-Mizrachi, MD

Associate Professor, Medicine
Division of Endocrinology, Metabolism and Lipid Research

Specialty Areas

Endocrinology
Metabolism
Diabetes

Board Certifications

Internal Medicine
Endocrinology, Diabetes and Metabolism

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Endocrinology, diabetes, metabolism

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Medicine Multispecialty Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 5
Office Phone: (314) 362-3500
Fax: (314) 362-7641

Education

Education

Fellowship: Endocrinology, Washington University School of Medicine, Barnes-Jewish Hospital, St. Louis, Missouri 2002
Residency: Internal Medicine, University of Miami, Jackson Memorial Hospital, Miami, Florida 1998
Residency: Internal Medicine, Universidad del Valle School of Medicine, Cali, Colombia 1995
Medical Degree: Universidad del Valle School of Medicine, Cali, Colombia 1990

Publication & Research

Publication & Research

Vitamin D<sub>3</sub> Supplementation Decreases a Unique Circulating Monocyte Cholesterol Pool in Patients with Type 2 Diabetes.
Riek AE, Oh J, Darwech I, Worthy V, Lin X, Ostlund RE Jr, Zhang RM, Bernal-Mizrachi C
J Steroid Biochem Mol Biol. 2017 Sep 20; pii: S0960-0760(17)30259-5. doi: 10.1016/j.jsbmb.2017.09.011.

PMID:
    28941998
    [PubMed - as supplied by publisher]
Related citations


Adiposity and Cardiometabolic Risk in Children With and Without Antipsychotic Drug Treatment.
Nicol GE, de Las Fuentes L, Riek AE, Bernal-Mizrachi C, Lenze EJ, Miller JP, Schweiger JA, Yingling MD, Huang VJ, Dixon DJ, Hennekens CH, Newcomer JW
J Clin Endocrinol Metab. 2015 Sep; 100(9)3418-26. doi: 10.1210/jc.2015-2119.

PMID:
    26186300
    [PubMed - indexed for MEDLINE]
Related citations


Deletion of macrophage Vitamin D receptor promotes insulin resistance and monocyte cholesterol transport to accelerate atherosclerosis in mice.
Oh J, Riek AE, Darwech I, Funai K, Shao J, Chin K, Sierra OL, Carmeliet G, Ostlund RE Jr, Bernal-Mizrachi C
Cell Rep. 2015 Mar 24; 10(11)1872-86.

PMID:
    25801026
    [PubMed - indexed for MEDLINE]
Related citations


25(OH) vitamin D suppresses macrophage adhesion and migration by downregulation of ER stress and scavenger receptor A1 in type 2 diabetes.
Riek AE, Oh J, Darwech I, Moynihan CE, Bruchas RR, Bernal-Mizrachi C
J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A172-9. doi: 10.1016/j.jsbmb.2013.10.016.

PMID:
    24184871
    [PubMed - indexed for MEDLINE]
Related citations


The St. Louis African American health-heart study: methodology for the study of cardiovascular disease and depression in young-old African Americans.
Bruchas RR, de Las Fuentes L, Carney RM, Reagan JL, Bernal-Mizrachi C, Riek AE, Gu CC, Bierhals A, Schootman M, Malmstrom TK, Burroughs TE, Stein PK, Miller DK, Dávila-Román VG
BMC Cardiovasc Disord. 2013 Sep 8; 1366. doi: 10.1186/1471-2261-13-66.

PMID:
    24011389
    [PubMed - indexed for MEDLINE]
Related citations


Hypotension due to Kir6.1 gain-of-function in vascular smooth muscle.
Li A, Knutsen RH, Zhang H, Osei-Owusu P, Moreno-Dominguez A, Harter TM, Uchida K, Remedi MS, Dietrich HH, Bernal-Mizrachi C, Blumer KJ, Mecham RP, Koster JC, Nichols CG
J Am Heart Assoc. 2013 Aug 23; 2(4)e000365. doi: 10.1161/JAHA.113.000365.

PMID:
    23974906
    [PubMed - indexed for MEDLINE]
Related citations


Vitamin D deficiency induces high blood pressure and accelerates atherosclerosis in mice.
Weng S, Sprague JE, Oh J, Riek AE, Chin K, Garcia M, Bernal-Mizrachi C
PLoS One. 2013; 8(1)e54625. doi: 10.1371/journal.pone.0054625.

PMID:
    23349943
    [PubMed - indexed for MEDLINE]
Related citations


1,25(OH)2 vitamin D suppresses macrophage migration and reverses atherogenic cholesterol metabolism in type 2 diabetic patients.
Riek AE, Oh J, Bernal-Mizrachi C
J Steroid Biochem Mol Biol. 2013 Jul; 136309-12. doi: 10.1016/j.jsbmb.2012.12.019.

PMID:
    23333932
    [PubMed - indexed for MEDLINE]
Related citations


Vitamin D suppression of endoplasmic reticulum stress promotes an antiatherogenic monocyte/macrophage phenotype in type 2 diabetic patients.
Riek AE, Oh J, Sprague JE, Timpson A, de las Fuentes L, Bernal-Mizrachi L, Schechtman KB, Bernal-Mizrachi C
J Biol Chem. 2012 Nov 9; 287(46)38482-94. doi: 10.1074/jbc.M112.386912.

PMID:
    23012375
    [PubMed - indexed for MEDLINE]
Related citations


Endoplasmic reticulum stress controls M2 macrophage differentiation and foam cell formation.
Oh J, Riek AE, Weng S, Petty M, Kim D, Colonna M, Cella M, Bernal-Mizrachi C
J Biol Chem. 2012 Apr 6; 287(15)11629-41. doi: 10.1074/jbc.M111.338673.

PMID:
    22356914
    [PubMed - indexed for MEDLINE]
Related citations


Enhanced hepatic apoA-I secretion and peripheral efflux of cholesterol and phospholipid in CD36 null mice.
Yue P, Chen Z, Nassir F, Bernal-Mizrachi C, Finck B, Azhar S, Abumrad NA
PLoS One. 2010 Mar 26; 5(3)e9906. doi: 10.1371/journal.pone.0009906.

PMID:
    20360851
    [PubMed - indexed for MEDLINE]
Related citations


Vitamin D regulates macrophage cholesterol metabolism in diabetes.
Riek AE, Oh J, Bernal-Mizrachi C
J Steroid Biochem Mol Biol. 2010 Jul; 121(1-2)430-3. doi: 10.1016/j.jsbmb.2010.03.018.

PMID:
    20338238
    [PubMed - indexed for MEDLINE]
Related citations


Implications of vitamin D deficiency in pregnancy and lactation.
Mulligan ML, Felton SK, Riek AE, Bernal-Mizrachi C
Am J Obstet Gynecol. 2010 May; 202(5)429.e1-9. doi: 10.1016/j.ajog.2009.09.002.

PMID:
    19846050
    [PubMed - indexed for MEDLINE]
Related citations


1,25(OH)2 vitamin d inhibits foam cell formation and suppresses macrophage cholesterol uptake in patients with type 2 diabetes mellitus.
Oh J, Weng S, Felton SK, Bhandare S, Riek A, Butler B, Proctor BM, Petty M, Chen Z, Schechtman KB, Bernal-Mizrachi L, Bernal-Mizrachi C
Circulation. 2009 Aug 25; 120(8)687-98. doi: 10.1161/CIRCULATIONAHA.109.856070.

PMID:
    19667238
    [PubMed - indexed for MEDLINE]
Related citations


Respiratory uncoupling in skeletal muscle delays death and diminishes age-related disease.
Gates AC, Bernal-Mizrachi C, Chinault SL, Feng C, Schneider JG, Coleman T, Malone JP, Townsend RR, Chakravarthy MV, Semenkovich CF
Cell Metab. 2007 Dec; 6(6)497-505.

PMID:
    18054318
    [PubMed - indexed for MEDLINE]
Related citations


An afferent vagal nerve pathway links hepatic PPARalpha activation to glucocorticoid-induced insulin resistance and hypertension.
Bernal-Mizrachi C, Xiaozhong L, Yin L, Knutsen RH, Howard MJ, Arends JJ, Desantis P, Coleman T, Semenkovich CF
Cell Metab. 2007 Feb; 5(2)91-102.

PMID:
    17276352
    [PubMed - indexed for MEDLINE]
Related citations


ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome.
Schneider JG, Finck BN, Ren J, Standley KN, Takagi M, Maclean KH, Bernal-Mizrachi C, Muslin AJ, Kastan MB, Semenkovich CF
Cell Metab. 2006 Nov; 4(5)377-89.

PMID:
    17084711
    [PubMed - indexed for MEDLINE]
Related citations


PPARalpha activation elevates blood pressure and does not correct glucocorticoid-induced insulin resistance in humans.
Subramanian S, DeRosa MA, Bernal-Mizrachi C, Laffely N, Cade WT, Yarasheski KE, Cryer PE, Semenkovich CF
Am J Physiol Endocrinol Metab. 2006 Dec; 291(6)E1365-71.

PMID:
    16868225
    [PubMed - indexed for MEDLINE]
Related citations


Fast predators or fast food, the fit still survive.
Bernal-Mizrachi C, Semenkovich CF
Nat Med. 2006 Jan; 12(1)46-7; discussion 47.

PMID:
    16397564
    [PubMed - indexed for MEDLINE]
Related citations


A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes.
Finck BN, Bernal-Mizrachi C, Han DH, Coleman T, Sambandam N, LaRiviere LL, Holloszy JO, Semenkovich CF, Kelly DP
Cell Metab. 2005 Feb; 1(2)133-44.

PMID:
    16054054
    [PubMed - indexed for MEDLINE]
Related citations