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Brian P. Hackett, PhD, MD

Professor, Pediatrics
Division of Newborn Medicine
Director, Fellowship Program

Specialty Areas

Newborn Medicine - Neonatology
Neonatal/Perinatal Medicine

Board Certifications

Neonatal-Perinatal Medicine
Pediatrics

Hospital Affiliations

Barnes-Jewish Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

High-risk newborn, critical care

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: Neonatal Intensive Care Unit (NICU), 5th Floor
Office Phone: 314-454-6148
Fax: 314-454-4633

Education

Education

Fellowship: Newborn Medicine, St. Louis Children's Hospital, St. Louis, Missouri 1992
Residency: Pediatrics, St. Louis Children's Hospital, St. Louis, Missouri 1989
Ph.D.: Biology, Boston College, Chesnut Hill, Massachusetts 1984
Medical Degree: St. Louis University, St. Louis, Missouri 1986
B.A.: Middlebury College, Middlebury, Vermont 1975

Publication & Research

Publication & Research

Functional Characterization of ABCA3 Mutations from Infants with Respiratory Distress Syndrome.
Wambach JA, Yang P, Wegner DJ, Heins HB, Kaliberova LN, Kaliberov SA, Curiel DT, White FV, Hamvas A, Hackett BP, Cole FS
Am J Respir Cell Mol Biol. 2016 Jul 2;

PMID:
    27374344
    [PubMed - as supplied by publisher]
Related citations


Surfactant protein-C promoter variants associated with neonatal respiratory distress syndrome reduce transcription.
Wambach JA, Yang P, Wegner DJ, An P, Hackett BP, Cole FS, Hamvas A
Pediatr Res. 2010 Sep; 68(3)216-20. doi: 10.1203/00006450-201011001-00421.

PMID:
    20539253
    [PubMed - indexed for MEDLINE]
Related citations


Foxj1 regulates asymmetric gene expression during left-right axis patterning in mice.
Zhang M, Bolfing MF, Knowles HJ, Karnes H, Hackett BP
Biochem Biophys Res Commun. 2004 Nov 26; 324(4)1413-20.

PMID:
    15504371
    [PubMed - indexed for MEDLINE]
Related citations


Foxj1 regulates basal body anchoring to the cytoskeleton of ciliated pulmonary epithelial cells.
Gomperts BN, Gong-Cooper X, Hackett BP
J Cell Sci. 2004 Mar 15; 117(Pt 8)1329-37.

PMID:
    14996907
    [PubMed - indexed for MEDLINE]
Related citations


Progressive lung disease and surfactant dysfunction with a deletion in surfactant protein C gene.
Hamvas A, Nogee LM, White FV, Schuler P, Hackett BP, Huddleston CB, Mendeloff EN, Hsu FF, Wert SE, Gonzales LW, Beers MF, Ballard PL
Am J Respir Cell Mol Biol. 2004 Jun; 30(6)771-6.

PMID:
    14656744
    [PubMed - indexed for MEDLINE]
Related citations


Formation and malformation of the vertebrate left-right axis.
Hackett BP
Curr Mol Med. 2002 Feb; 2(1)39-66.

PMID:
    11898848
    [PubMed - indexed for MEDLINE]
Related citations


Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry.
Chen J, Knowles HJ, Hebert JL, Hackett BP
J Clin Invest. 1998 Sep 15; 102(6)1077-82.

PMID:
    9739041
    [PubMed - indexed for MEDLINE]
Related citations


Intraoperative localization of small intestinal bleeding in an infant by methylene blue injection: a case report.
Mazziotti MV, Muldowney S, Darcy M, Hackett BP, Skinner MA
J Pediatr Surg. 1998 May; 33(5)754-5.

PMID:
    9607490
    [PubMed - indexed for MEDLINE]
Related citations


A human forkhead/winged-helix transcription factor expressed in developing pulmonary and renal epithelium.
Pelletier GJ, Brody SL, Liapis H, White RA, Hackett BP
Am J Physiol. 1998 Mar; 274(3 Pt 1)L351-9.

PMID:
    9530170
    [PubMed - indexed for MEDLINE]
Related citations


Structural characterization of the mouse Hfh4 gene, a developmentally regulated forkhead family member.
Brody SL, Hackett BP, White RA
Genomics. 1997 Nov 1; 45(3)509-18.

PMID:
    9367675
    [PubMed - indexed for MEDLINE]
Related citations


Mechanisms of gene expression and cell fate determination in the developing pulmonary epithelium.
Hackett BP, Bingle CD, Gitlin JD
Annu Rev Physiol. 1996; 5851-71.

PMID:
    8815806
    [PubMed - indexed for MEDLINE]
Related citations


Role of hepatocyte nuclear factor-3 alpha and hepatocyte nuclear factor-3 beta in Clara cell secretory protein gene expression in the bronchiolar epithelium.
Bingle CD, Hackett BP, Moxley M, Longmore W, Gitlin JD
Biochem J. 1995 May 15; 308 ( Pt 1)197-202.

PMID:
    7755566
    [PubMed - indexed for MEDLINE]
Related citations


Primary structure of hepatocyte nuclear factor/forkhead homologue 4 and characterization of gene expression in the developing respiratory and reproductive epithelium.
Hackett BP, Brody SL, Liang M, Zeitz ID, Bruns LA, Gitlin JD
Proc Natl Acad Sci U S A. 1995 May 9; 92(10)4249-53.

PMID:
    7753791
    [PubMed - indexed for MEDLINE]
Related citations


5' flanking region of the Clara cell secretory protein gene specifies a unique temporal and spatial pattern of gene expression in the developing pulmonary epithelium.
Hackett BP, Gitlin JD
Am J Respir Cell Mol Biol. 1994 Aug; 11(2)123-9.

PMID:
    8049073
    [PubMed - indexed for MEDLINE]
Related citations


Cell-specific expression of a Clara cell secretory protein-human growth hormone gene in the bronchiolar epithelium of transgenic mice.
Hackett BP, Gitlin JD
Proc Natl Acad Sci U S A. 1992 Oct 1; 89(19)9079-83.

PMID:
    1409605
    [PubMed - indexed for MEDLINE]
Related citations


Clara cell secretory protein gene expression in bronchiolar epithelium.
Hackett BP, Shimizu N, Gitlin JD
Am J Physiol. 1992 Apr; 262(4 Pt 1)L399-404.

PMID:
    1566856
    [PubMed - indexed for MEDLINE]
Related citations