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Brian P. Hackett, PhD, MD

Professor, Pediatrics
Division of Newborn Medicine
Director, Fellowship Program

Specialty Areas

Newborn Medicine - Neonatology
Neonatal/Perinatal Medicine

Board Certifications

Neonatal-Perinatal Medicine
Pediatrics

Hospital Affiliations

Barnes-Jewish Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

High-risk newborn, critical care

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: Neonatal Intensive Care Unit (NICU), 5th Floor
Office Phone: 314-454-6148
Fax: 314-454-4633

Education

Education

Fellowship: Newborn Medicine, St. Louis Children's Hospital, St. Louis, Missouri 1992
Residency: Pediatrics, St. Louis Children's Hospital, St. Louis, Missouri 1989
Ph.D.: Biology, Boston College, Chesnut Hill, Massachusetts 1984
Medical Degree: St. Louis University, St. Louis, Missouri 1986
B.A.: Middlebury College, Middlebury, Vermont 1975

Publication & Research

Publication & Research

Surfactant protein-C promoter variants associated with neonatal respiratory distress syndrome reduce transcription.
Wambach JA, Yang P, Wegner DJ, An P, Hackett BP, Cole FS, Hamvas A
Pediatr Res. 2010 Sep; 68(3)216-20. doi: 10.1203/00006450-201011001-00421.

PMID:
    20539253
    [PubMed - indexed for MEDLINE]
Related citations


Foxj1 regulates asymmetric gene expression during left-right axis patterning in mice.
Zhang M, Bolfing MF, Knowles HJ, Karnes H, Hackett BP
Biochem Biophys Res Commun. 2004 Nov 26; 324(4)1413-20.

PMID:
    15504371
    [PubMed - indexed for MEDLINE]
Related citations


Foxj1 regulates basal body anchoring to the cytoskeleton of ciliated pulmonary epithelial cells.
Gomperts BN, Gong-Cooper X, Hackett BP
J Cell Sci. 2004 Mar 15; 117(Pt 8)1329-37.

PMID:
    14996907
    [PubMed - indexed for MEDLINE]
Related citations


Progressive lung disease and surfactant dysfunction with a deletion in surfactant protein C gene.
Hamvas A, Nogee LM, White FV, Schuler P, Hackett BP, Huddleston CB, Mendeloff EN, Hsu FF, Wert SE, Gonzales LW, Beers MF, Ballard PL
Am J Respir Cell Mol Biol. 2004 Jun; 30(6)771-6.

PMID:
    14656744
    [PubMed - indexed for MEDLINE]
Related citations


Formation and malformation of the vertebrate left-right axis.
Hackett BP
Curr Mol Med. 2002 Feb; 2(1)39-66.

PMID:
    11898848
    [PubMed - indexed for MEDLINE]
Related citations


Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry.
Chen J, Knowles HJ, Hebert JL, Hackett BP
J Clin Invest. 1998 Sep 15; 102(6)1077-82.

PMID:
    9739041
    [PubMed - indexed for MEDLINE]
Related citations


Intraoperative localization of small intestinal bleeding in an infant by methylene blue injection: a case report.
Mazziotti MV, Muldowney S, Darcy M, Hackett BP, Skinner MA
J Pediatr Surg. 1998 May; 33(5)754-5.

PMID:
    9607490
    [PubMed - indexed for MEDLINE]
Related citations


A human forkhead/winged-helix transcription factor expressed in developing pulmonary and renal epithelium.
Pelletier GJ, Brody SL, Liapis H, White RA, Hackett BP
Am J Physiol. 1998 Mar; 274(3 Pt 1)L351-9.

PMID:
    9530170
    [PubMed - indexed for MEDLINE]
Related citations


Structural characterization of the mouse Hfh4 gene, a developmentally regulated forkhead family member.
Brody SL, Hackett BP, White RA
Genomics. 1997 Nov 1; 45(3)509-18.

PMID:
    9367675
    [PubMed - indexed for MEDLINE]
Related citations


Mechanisms of gene expression and cell fate determination in the developing pulmonary epithelium.
Hackett BP, Bingle CD, Gitlin JD
Annu Rev Physiol. 1996; 5851-71.

PMID:
    8815806
    [PubMed - indexed for MEDLINE]
Related citations


Role of hepatocyte nuclear factor-3 alpha and hepatocyte nuclear factor-3 beta in Clara cell secretory protein gene expression in the bronchiolar epithelium.
Bingle CD, Hackett BP, Moxley M, Longmore W, Gitlin JD
Biochem J. 1995 May 15; 308 ( Pt 1)197-202.

PMID:
    7755566
    [PubMed - indexed for MEDLINE]
Related citations


Primary structure of hepatocyte nuclear factor/forkhead homologue 4 and characterization of gene expression in the developing respiratory and reproductive epithelium.
Hackett BP, Brody SL, Liang M, Zeitz ID, Bruns LA, Gitlin JD
Proc Natl Acad Sci U S A. 1995 May 9; 92(10)4249-53.

PMID:
    7753791
    [PubMed - indexed for MEDLINE]
Related citations


5' flanking region of the Clara cell secretory protein gene specifies a unique temporal and spatial pattern of gene expression in the developing pulmonary epithelium.
Hackett BP, Gitlin JD
Am J Respir Cell Mol Biol. 1994 Aug; 11(2)123-9.

PMID:
    8049073
    [PubMed - indexed for MEDLINE]
Related citations


Cell-specific expression of a Clara cell secretory protein-human growth hormone gene in the bronchiolar epithelium of transgenic mice.
Hackett BP, Gitlin JD
Proc Natl Acad Sci U S A. 1992 Oct 1; 89(19)9079-83.

PMID:
    1409605
    [PubMed - indexed for MEDLINE]
Related citations


Clara cell secretory protein gene expression in bronchiolar epithelium.
Hackett BP, Shimizu N, Gitlin JD
Am J Physiol. 1992 Apr; 262(4 Pt 1)L399-404.

PMID:
    1566856
    [PubMed - indexed for MEDLINE]
Related citations