Patient Portal

Barbara Joy Snider, MD, PhD

Associate Professor, Neurology
Division of Adult Neurology

Specialty Areas

Neurology - Adult
Memory Disorders and Diagnosis
Alzheimer's Disease
Dementia

Board Certifications

Neurology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Neurodegenerative disorders, specifically diagnosis and treatment of patients with dementing disorders, memory disorders, Alzheimer's disease, dementia

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Memory Diagnostic Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: (314) 286-1967
Fax: (314) 286-1985
Email: sniderj@neuro.wustl.edu

Education

Education

Residency: Neurology, Southwestern Medical School/Parkland Memorial Hospital, Dallas, Texas 1993
Ph.D.: Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 1989
Medical Degree: University Of Texas Southwestern Medical Center, Dallas, Texas 1989
B.A.: Biology, Northwestern University, Evanston, Illinois 1979

Publication & Research

Publication & Research

Effect of apolipoprotein E4 on clinical, neuroimaging, and biomarker measures in noncarrier participants in the Dominantly Inherited Alzheimer Network.
Bussy A, Snider BJ, Coble D, Xiong C, Fagan AM, Cruchaga C, Benzinger TLS, Gordon BA, Hassenstab J, Bateman RJ, Morris JC, Dominantly Inherited Alzheimer Network.
Neurobiol Aging. 2018 Oct 13; 7542-50. doi: 10.1016/j.neurobiolaging.2018.10.011.

PMID:
    30530186
    [PubMed - as supplied by publisher]
Related citations


Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease.
Roh JH, Jiang H, Finn MB, Stewart FR, Mahan TE, Cirrito JR, Heda A, Snider BJ, Li M, Yanagisawa M, de Lecea L, Holtzman DM
J Exp Med. 2014 Dec 15; 211(13)2487-96. doi: 10.1084/jem.20141788.

PMID:
    25422493
    [PubMed - indexed for MEDLINE]
Related citations


Proteasome inhibitors activate autophagy involving inhibition of PI3K-Akt-mTOR pathway as an anti-oxidation defense in human RPE cells.
Tang B, Cai J, Sun L, Li Y, Qu J, Snider BJ, Wu S
PLoS One. 2014; 9(7)e103364. doi: 10.1371/journal.pone.0103364.

PMID:
    25062253
    [PubMed - indexed for MEDLINE]
Related citations


The influence of cerebrospinal fluid (CSF) biomarkers on clinical dementia evaluations.
Gooblar J, Carpenter BD, Coats MA, Morris JC, Snider BJ
Alzheimers Dement. 2015 May; 11(5)533-540.e2. doi: 10.1016/j.jalz.2014.04.517.

PMID:
    25022536
    [PubMed - indexed for MEDLINE]
Related citations


Reductions of the components of the calreticulin/calnexin quality-control system by proteasome inhibitors and their relevance in a rodent model of Parkinson's disease.
Kuang XL, Liu F, Chen H, Li Y, Liu Y, Xiao J, Shan G, Li M, Snider BJ, Qu J, Barger SW, Wu S
J Neurosci Res. 2014 Oct; 92(10)1319-29. doi: 10.1002/jnr.23413.

PMID:
    24860980
    [PubMed - indexed for MEDLINE]
Related citations


Dominantly Inherited Alzheimer Network: facilitating research and clinical trials.
Moulder KL, Snider BJ, Mills SL, Buckles VD, Santacruz AM, Bateman RJ, Morris JC
Alzheimers Res Ther. 2013; 5(5)48. doi: 10.1186/alzrt213.

PMID:
    24131566
    [PubMed]
Related citations


"Will I get Alzheimer disease?" when cognitively normal patients ask to be tested for Alzheimer disease.
Snider BJ, Buckles VD
Continuum (Minneap Minn). 2013 Apr; 19(2 Dementia)470-4. doi: 10.1212/01.CON.0000429171.50686.07.

PMID:
    23558490
    [PubMed - indexed for MEDLINE]
Related citations


Pretreatment with proteasome inhibitors protects against oxidative injuries via PPARα-dependent and -independent pathways in ARPE-19 cells.
Cai J, Sun L, Lin B, Wu M, Qu J, Snider BJ, Wu S
Invest Ophthalmol Vis Sci. 2012 Aug 31; 53(9)5967-74. doi: 10.1167/iovs.12-10048.

PMID:
    22879419
    [PubMed - indexed for MEDLINE]
Related citations


Safety and biomarker effects of solanezumab in patients with Alzheimer's disease.
Farlow M, Arnold SE, van Dyck CH, Aisen PS, Snider BJ, Porsteinsson AP, Friedrich S, Dean RA, Gonzales C, Sethuraman G, DeMattos RB, Mohs R, Paul SM, Siemers ER
Alzheimers Dement. 2012 Jul; 8(4)261-71. doi: 10.1016/j.jalz.2011.09.224.

PMID:
    22672770
    [PubMed - indexed for MEDLINE]
Related citations


Production of lentiviral vectors for transducing cells from the central nervous system.
Li M, Husic N, Lin Y, Snider BJ
J Vis Exp. 2012 May 24; (63)e4031. doi: 10.3791/4031.

PMID:
    22664962
    [PubMed - indexed for MEDLINE]
Related citations


Translational biomarkers: from preclinical to clinical a report of 2009 AAPS/ACCP Biomarker Workshop.
Bai JP, Bell R, Buckman S, Burckart GJ, Eichler HG, Fang KC, Goodsaid FM, Jusko WJ, Lesko LL, Meibohm B, Patterson SD, Puig O, Smerage JB, Snider BJ, Wagner JA, Wang J, Walton MK, Weiner R
AAPS J. 2011 Jun; 13(2)274-83. doi: 10.1208/s12248-011-9265-x.

PMID:
    21448748
    [PubMed - indexed for MEDLINE]
Related citations


Optimal promoter usage for lentiviral vector-mediated transduction of cultured central nervous system cells.
Li M, Husic N, Lin Y, Christensen H, Malik I, McIver S, LaPash Daniels CM, Harris DA, Kotzbauer PT, Goldberg MP, Snider BJ
J Neurosci Methods. 2010 May 30; 189(1)56-64. doi: 10.1016/j.jneumeth.2010.03.019.

PMID:
    20347873
    [PubMed - indexed for MEDLINE]
Related citations


A role for the ubiquitin-proteasome system in activity-dependent presynaptic silencing.
Jiang X, Litkowski PE, Taylor AA, Lin Y, Snider BJ, Moulder KL
J Neurosci. 2010 Feb 3; 30(5)1798-809. doi: 10.1523/JNEUROSCI.4965-09.2010.

PMID:
    20130189
    [PubMed - indexed for MEDLINE]
Related citations


Translational biomarkers for accelerating drug development: From preclinical to clinical - AAPS Workshop.
Snider BJ
IDrugs. 2009 Jul; 12(7)428-31.

PMID:
    19579162
    [PubMed - indexed for MEDLINE]
Related citations


Cellular calcium deficiency plays a role in neuronal death caused by proteasome inhibitors.
Wu S, Hyrc KL, Moulder KL, Lin Y, Warmke T, Snider BJ
J Neurochem. 2009 Jun; 109(5)1225-36. doi: 10.1111/j.1471-4159.2009.06037.x.

PMID:
    19476541
    [PubMed - indexed for MEDLINE]
Related citations


Cerebrospinal fluid biomarkers and rate of cognitive decline in very mild dementia of the Alzheimer type.
Snider BJ, Fagan AM, Roe C, Shah AR, Grant EA, Xiong C, Morris JC, Holtzman DM
Arch Neurol. 2009 May; 66(5)638-45. doi: 10.1001/archneurol.2009.55.

PMID:
    19433664
    [PubMed - indexed for MEDLINE]
Related citations


Transplantation of embryonic stem cells improves nerve repair and functional recovery after severe sciatic nerve axotomy in rats.
Cui L, Jiang J, Wei L, Zhou X, Fraser JL, Snider BJ, Yu SP
Stem Cells. 2008 May; 26(5)1356-65. doi: 10.1634/stemcells.2007-0333.

PMID:
    18308951
    [PubMed - indexed for MEDLINE]
Related citations


Transient encephalopathy in a postoperative non-alcoholic female with Marchiafava-Bignami disease.
Rusche-Skolarus LE, Lucey BP, Vo KD, Snider BJ
Clin Neurol Neurosurg. 2007 Oct; 109(8)713-5.

PMID:
    17583421
    [PubMed - indexed for MEDLINE]
Related citations


Novel presenilin 1 mutation (S170F) causing Alzheimer disease with Lewy bodies in the third decade of life.
Snider BJ, Norton J, Coats MA, Chakraverty S, Hou CE, Jervis R, Lendon CL, Goate AM, McKeel DW Jr, Morris JC
Arch Neurol. 2005 Dec; 62(12)1821-30.

PMID:
    16344340
    [PubMed - indexed for MEDLINE]
Related citations


Calcium in Alzheimer's disease pathogenesis: too much, too little or in the wrong place?
Canzoniero LM, Snider BJ
J Alzheimers Dis. 2005 Nov; 8(2)147-54; discussion 209-15.

PMID:
    16308483
    [PubMed - indexed for MEDLINE]
Related citations